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https://www.itmat.upenn.edu/cnsc/

Provides expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, nanoparticle production and surface functionalization, and site-specific antibody labeling. Our chemists provide custom, problem specific support for researchers in medical, chemical, and materials science fields. Specific services include consultation and assistance with the design of chemical/medicinal compounds, in house synthesis of chemical/medicinal compounds, custom nanoparticle design and synthesis, custom nanoparticle surface functionalization, polymer and dendrimer synthesis, and site specific antibody labeling.

Proper citation: University of Pennsylvania Perelman School of Medicine Chemical and Nanoparticle Synthesis Core Facility (RRID:SCR_022390) Copy   

•   Source: SciCrunch Registry

https://wiki.umontreal.ca/spaces/plateformes/pages/189568061/Core+Facilities+-+CI2B

Offers instruments and services to support research in microscopy.

Proper citation: University of Montreal BioImaging Platform Core Facility (RRID:SCR_022311) Copy   

•   Source: SciCrunch Registry

https://hostmicrobe.org/

Provides services in disciplines of genomics, microbiology and immunology. We engage in collaborative projects that benefit from close interactions with veterinarians and human clinicians alike.

Proper citation: University of Pennsylvania School of Veterinary Medicine Center for Host Microbial Interactions Core Facility (RRID:SCR_022310) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cbica/

Offers development and application of advanced computational and analytical techniques that quantify morphology and function from biomedical images, as well as on relating imaging phenotypes to genetic and molecular characterizations, and on integrating this information into diagnostic and predictive tools in era of personalized medicine. Computational methods can contribute significantly to automated, reproducible and quantitative interpretations of biomedical images. Translates advanced computational and analytical imaging methods to clinic, by providing forum in which interactions between researchers and clinicians facilitate bidirectional flow of ideas, algorithms and data between laboratory and clinic.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Biomedical Image Computing and Analytics Core Facility (RRID:SCR_022397) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CAMIPM/

Core dedicated to development and application of innovative, novel magnetic resonance and optical imaging techniques. Provides research and computing resources for projects with focus on developing instrumentation, methodologies, and data analysis techniques for quantitative assessment of functional, structural, and metabolic parameters in humans with use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Metabolic Imaging in Precision Medicine Core Facility (RRID:SCR_022396) Copy   

•   Source: SciCrunch Registry

https://pennbrain.upenn.edu/

Provides infrastructure support for research on human cognition, perception, affect, disordered cognition, and extension to preclinical models. By consolidating methodological expertise in these domain areas as services, center seeks to facilitate cutting edge research using largely shared set of methods and tools for elucidating brain behavior relationships in health and disease.

Proper citation: University of Pennsylvania Perelman School of Medicine Brain Science Service Center Core Facility (RRID:SCR_022394) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/drc/cores/rodent.html

Core (RMPC, formerly MPPMC) is metabolic core. Offers technology and phenotyping services to allow investigators to study metabolism in pre-clinical rodent models. Services include measurements of body composition (fat and lean mass) using NMR and DEXA, energy balance (food intake, locomotor activity, energy expenditure) using indirect calorimetry in either Columbus Instruments CLAMS system or Sable Systems Promethion System (with optional gas analyzer), and other in vivo metabolic phenotyping services (glucose clamps, insulin and glucose tolerance tests, telemetric monitoring of blood glucose or blood pressure, bomb calorimetry).

Proper citation: University of Pennsylvania Perelman School of Medicine Rodent Metabolic Phenotyping Core Facility (RRID:SCR_022427) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ipsccore/

Provides resources for disseminating human pluripotent stem cell technology within UPenn and surrounding research communities. �Our services include derivation of patient specific iPSCs, genome engineering of stem cell lines using CRISPR/Cas9 technology, and lineage specific differentiation of iPSCs/hESCs in 2D and 3D organoid culture.�Core has large collection of patient derived iPSC lines and cell lines of gastrointestinal tract (esophageal, pancreatic and intestinal) available to users.�Committed to training investigators in stem cell culture techniques and providing quality tested stem cell reagents to users.

Proper citation: University of Pennsylvania Perelman School of Medicine Induced Pluripotent Stem Cell Core Facility (RRID:SCR_022426) Copy   

•   Source: SciCrunch Registry

https://qb3.berkeley.edu/facility/ctaf-htsf/

Facility provides expert staff for training, services, and cell culturing space for HT automated cell seeding, liquid handling equipment, multi label plate reader and high content automated confocal imaging for any type of multi well, multi conditional mammalian cell experiments.

Proper citation: University of California at Berkeley QB3 High Throughput Screening CoreFacility (RRID:SCR_022304) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ris/

Shared resource machine shop serving various University of Pennsylvania Schools and Departments. Assists researchers to design and construct both laboratory and clinical instruments.

Proper citation: University of Pennsylvania Perelman School of Medicine Research Instrumentation Shop Core Facility (RRID:SCR_022424) Copy   

•   Source: SciCrunch Registry

https://it.hms.harvard.edu/rc/core

Promotes deeper collaboration across Harvard biomedical research ecosystem.This includes improved capabilities and performance by establishing more transparent and sustainable IT services for our research community.

Proper citation: Harvard Medical School Research Computing Core Facility (RRID:SCR_022289) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/

Provides Becton Dickinson LSR II flow cytometer equipped with four lasers.Blue laser can be used to detect forward and side scatter and 4 colors (eg., FITC/Alexa 488, PE, PerCP-CY55, PE-CY7), red laser can be used to detect 2 colors (e.g., APC and APC-CY7), violet laser can be used to detect 2 colors (e.g., Pacific blue, Am cyan) and a UV laser which can also be used to detect 2 colors (e.g., INDO1 blue, Indo1-violet/DAPI). The instrument is located in Room 330 in the Levy Building (240 South 40th Street).

Proper citation: University of Pennsylvania Penn Dental Medicine Flow Cytometry Core Facility (RRID:SCR_022443) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/polymeric-and-optical-materials-characterization-shared-facility

Facility specializes in material characterization of polymers, hydrogels, liquid crystals, and composites.

Proper citation: University of Colorado Boulder Polymeric and Optical Materials Characterization Shared Core Facility (RRID:SCR_022288) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models

Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�

Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy   

•   Source: SciCrunch Registry

https://www.abdn.ac.uk/ims/facilities/cytometry/

Provides services and expertise in flow cytometry to government agencies, industry, educational and private individuals.

Proper citation: University of Aberdeen Iain Fraser Cytometry Centre Core Facility (RRID:SCR_022315) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/flow-image-cytometry

Provides advanced flow cytometric and morphology services at cellular and subcellular levels of resolution.Services include investigator access to equipment, education and consultation, comprehensive sample processing, data acquisition and data analysis, luminex cytokine, chemokine and growth factor quantification, and core flow cytometry services for investigator and biotech sponsored clinical trials.

Proper citation: Roswell Park Cancer Institute Flow and Image Cytometry Shared Resource Core Facility (RRID:SCR_022313) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/electronmicroscopyresourcelab/

Training and service facility dedicated to providing both conventional transmission electron microscopy of cells and tissues and state of the art cryo-electron microscopy and cryo-electron tomography for structural investigation of macromolecules and cells.

Proper citation: University of Pennsylvania Perelman School of Medicine Electron Microscopy Resource Lab Core Facility (RRID:SCR_022375) Copy   

•   Source: SciCrunch Registry

https://bioinfo.med.upenn.edu/

Core provides bioinformatics services that include data analysis and consultation and building of efficient pipelines that handle various biomedical data including Next-Generation Sequencing (NGS) data.

Proper citation: University of Pennsylvania Perelman School of Medicine Bioinformatics Core Facility (RRID:SCR_022374) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cdbmicroscopycore/

Core provides personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to assistance with image data analysis. Facility houses confocal microscopes, Bruker Vutara 352 super resolution system, Zeiss Z.1 Lightsheet system, three widefield light microscopes, and several computers dedicated to image processing and analysis. Offers scanning electron microscope sample preparation and imaging.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Developmental Biology Microscopy Core Facility (RRID:SCR_022373) Copy   

•   Source: SciCrunch Registry