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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Web Game for Collaborative Labeling
 
Resource Report
Resource Website
1+ mentions
Web Game for Collaborative Labeling (RRID:SCR_006685) Web Game for Collaborative Labeling software resource Web game that provides an innovative infrastructure for labeling to enable an alternative to expert raters for medical image labeling through statistical analysis of the collaborative efforts of many, minimally-trained raters. Statistical atlases of regional brain anatomy have proven to be extremely useful in characterizing the relationship between the structure and function of the human nervous system. Typically, an expert human rater manually examines each slice of a three-dimensional volume. This approach can be exceptionally time and resource intensive, so cost severely limits the clinical studies where subject-specific labeling is feasible. Methods for improved efficiency and reliability of manual labeling would be of immense benefit for clinical investigation into morphological correlates of brain function. magnetic resonance, labeling, crowdsourcing is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) GNU Lesser General Public License nlx_156019 http://www.nitrc.org/projects/webmill SCR_006685 2026-02-14 02:01:20 2
SoftSearch
 
Resource Report
Resource Website
1+ mentions
SoftSearch (RRID:SCR_006683) SoftSearch software resource A sensitive structural variant (SV) detection software tool for Illumina paired-end next-generation sequencing data. It simultaneously utilizes soft-clipping and read-pair strategies for detecting SVs to increase sensitivity. Soft clips are proxies for split-reads that indicate part of the read maps to the reference genome, but the other part is not localized at the same place (e.g. breakpoint spanning reads). Discordant read-pairs refer to a read and its mate, where the insert size is greater (or less than) the expected distribution of the dataset ? or ? where the mapping orientation of the reads is unexpected (e.g. both on the same strand). SoftSearch looks for areas with soft-clipping in the genome that have discordant read pairs supporting the anomaly. Once areas with both these conditions are identified, the read and mate information is extracted directly from the BAM file containing the discordant reads, obviating the need for time-consuming and error-prone complex alignment strategies. Only a small number of soft-masked bases discordant read-pairs are necessary to identify an SV, which on their own would not be sufficient to make an SV call, thus highlighting SoftSearch?s improved sensitivity. SoftSearch is well suited to be ?plugged in? to most sequence analysis workflows, since it requires standard file inputs, such as a BAM file using almost any aligner and a reference genome FASTA file. Because SoftSearch requires soft-masked bases, the only requirement is that the aligner must have this functionality, which is usually turned on by default by many standard aligners (e.g. BWA, Novoalign, etc). illumina, structural variant, next-generation sequencing, perl, academic is listed by: OMICtools
has parent organization: Google Code
GNU General Public License, v2 OMICS_00322 SCR_006683 SoftSearch - Detecting Structural Variations Using Split Reads and Discordant Read Pairs 2026-02-14 02:01:11 5
GREC Corpus
 
Resource Report
Resource Website
1+ mentions
GREC Corpus (RRID:SCR_006719) GREC training set A semantically annotated corpus of 240 MEDLINE abstracts (167 on the subject of E. coli species and 73 on the subject of the Human species) intended for training information extraction (IE) systems and/or resources which are used to extract events from biomedical literature. The corpus has been manually annotated with events relating to gene regulation by biologists. Each event is centered on either a verb (e.g. transcribe) or nominalized verb (e.g. transcription) and annotation consists of identifying, as exhaustively as possible, the structurally-related arguments of the verb or nominalized verb within the same sentence. Each event argument is then assigned the following information: * A semantic role from a fixed set of 13 roles which are tailored to the biomedical domain. * A biomedical concept type (where appropriate). The corpus in available for download in 2 formats: * A standoff format, based on the BioNLP'09 Shared Task format * An XML format, based on the GENIA event annotation format annotation, information extraction, text mining, semantic role, semantic search, gene, computational linguistics, gene regulation is listed by: FORCE11
is related to: MEDLINE
has parent organization: National Centre for Text Mining
JISC PMID:19852798 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported, For Copyright of abstracts refer to PubMed. nif-0000-06688 SCR_006719 Gene Event Regulation Corpus 2026-02-14 02:01:12 3
InnateDB
 
Resource Report
Resource Website
100+ mentions
InnateDB (RRID:SCR_006714) InnateDB data or information resource, database Publicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralized resource. The database can be mined as a knowledgebase or used with the integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response. Although InnateDB curation focuses on innate immunity-relevant interactions and pathways, it also incorporates detailed annotation on the entire human, mouse and bovine interactomes by integrating data (178,000+ interactions & 3,900+ pathways) from several of the major public interaction and pathway databases. InnateDB also has integrated human, mouse and bovine orthology predictions generated using Ortholgue software. Ortholgue uses a phylogenetic distance-based method to identify possible paralogs in high-throughput orthology predictions. Integrated human and mouse conserved gene order and synteny information has also been determined to provide further support for orthology predictions. InnateDB Capabilities: * View statistics for manually-curated innate immunity relevant molecular interactions. New manually curated interactions are submitted weekly. * Search for genes and proteins of interest. * Search for experimentally-verified molecular interactions by gene/protein name, interaction type, cell type, etc. * Search genes/interactions belonging to 3,900 pathways. * Visualize interactions using an intuitive subcellular localization-based layout in Cerebral. * Upload your own list of genes along with associated gene expression data (from up to 10 experimental conditions) to interactively analyze this data in a molecular interaction network context. Once you have uploaded your data, you will be able to interactively visualize interaction networks with expression data overlaid; carry out Pathway, Gene Ontology and Transcription Factor Binding Site over-representation analyses; construct orthologous interaction networks in other species; and much more. * Access curated interaction data via a dedicated PSICQUIC webservice. gene, immune response, pathway, protein, signaling pathway, interaction, immune, signaling response, gene, orthology prediction, orthology, ortholg, annotation, interactome, gene expression, molecule, protein-protein interaction, molecular interaction, visualization, nucleic acid-protein, nucleic acid, network, web service, transcription factor binding site, software resource, FASEB list is listed by: re3data.org
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: PSICQUIC Registry
is related to: Gene Ontology
is related to: IntAct
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: University of British Columbia; British Columbia; Canada
works with: IMEx - The International Molecular Exchange Consortium
Microbial infection, Allergy, Asthma Michael Smith Foundation for Health Research ;
AllerGen 12ASI1;
AllerGen 12B&B2;
Teagasc RMIS6018;
European Union PSIMEx project contract FP7-HEALTH-2007-223411
PMID:23180781
PMID:18766178
Free, Freely available nif-0000-20808, r3d100010676 https://doi.org/10.17616/R36S43 SCR_006714 A Knowledge Resource for Innate Immunity Interactions and Pathways, InnateDB: Systems Biology of the Innate Immune Response, InnateDB - A Knowledge Resource for Innate Immunity Interactions and Pathways 2026-02-14 02:01:14 496
Grants.gov
 
Resource Report
Resource Website
10+ mentions
Grants.gov (RRID:SCR_002661) funding resource A source to FIND and APPLY for federal grants. The U.S. Department of Health and Human Services is proud to be the managing partner for Grants.gov, an initiative that is having an unparalleled impact on the grant community. All discretionary grants offered by the 26 federal grant-making agencies can be found on Grants.gov. Grants.gov was established as a governmental resource named the E-Grants Initiative, part of the President's 2002 Fiscal Year Management Agenda to improve government services to the public. The concept has its origins in the Federal Financial Assistance Management Improvement Act of 1999, also known as Public Law 106-107. Public Law 106-107 has since sunset and is now known as the Grants Policy Committee (GPC). For more information on the Grants Policy Committee, click here. Today, Grants.gov is a central storehouse for information on over 1,000 grant programs and provides access to approximately $500 billion in annual awards. You may find information on *What is a Grant? *Who is Eligible for a Grant? *Program highlights and accomplishments *Grants.gov in the News (Articles, press releases, milestones and events) *Program Status (Detailed information about our relationship with partner federal agencies, financial contributions, grant opportunities, fiscal reports, planning strategies and statistics.) grant, funding, award, database, opportunity is used by: NIF Data Federation
is used by: Aging Portal
is used by: NIDDK Information Network (dkNET)
Free, Freely available nif-0000-22393 SCR_002661 2026-02-14 02:00:29 36
NiBabel
 
Resource Report
Resource Website
100+ mentions
NiBabel (RRID:SCR_002498) NiBabel software resource A Python package for reading and writing a variety of medical and neuroimaging file formats. This includes: ANALYZE (plain, SPM99, SPM2), NIfTI1, as well as MINC. NiBabel is the successor of PyNIfTI. magnetic resonance, python, neuroimaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: PyNIfTI
is related to: MNE software
has parent organization: Neuroimaging in Python
Free, Available for download, Freely available nlx_155896 http://www.nitrc.org/projects/nibabel SCR_002498 NIPY File IO 2026-02-14 02:00:25 122
Pythagorean Displacement and Motion Regressors
 
Resource Report
Resource Website
1+ mentions
Pythagorean Displacement and Motion Regressors (RRID:SCR_002525) Pythagorean Displacement and Motion Regressors software resource Matlab script that uses the Pythagorean Theorem to calculate head motion and position, while preserving degrees of freedom. The motion parameters output by SPM (rp*.txt) estimate head position relative to the first volume in 3D translation and 3D rotation, which are often entered as a nuisance regressor during individual-level statistics. Regressing the total displacement and relative position can potentially explain more variance in voxel-level BOLD signals that is related to head movement during an fMRI experiment. algorithm, magnetic resonance, matlab, pythagorean theorem, head, motion, position, fmri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155931 SCR_002525 2026-02-14 02:00:26 5
Signed Differential Mapping
 
Resource Report
Resource Website
100+ mentions
Signed Differential Mapping (RRID:SCR_002554) SDM software resource Statistical method and software for conducting image- and coordinate-based meta-analysis of neuroimaging studies investigating differences in brain activity (e.g. BOLD response in fMRI, metabolism in PET) or structure (e.g. gray matter volume in VBM, voxel-based or TBSS white matter fractional anisotropy in DTI, etcetera). magnetic resonance, pet, spect, fmri, vbm, meta-analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155962 http://www.nitrc.org/projects/sdm SCR_002554 2026-02-14 02:00:27 150
MBASED
 
Resource Report
Resource Website
10+ mentions
MBASED (RRID:SCR_002584) software resource Software package containing functions for allele-specific gene expression (ASE) analysis using meta-analysis based allele-specific expression detection. software package, unix/linux, mac os x, windows, r, gene expression, sequencing, transcription is listed by: OMICtools
has parent organization: Bioconductor
PMID:25315065 Free, Available for download, Freely available OMICS_05502 http://www.bioconductor.org/packages/release/bioc/html/MBASED.html SCR_002584 Meta-analysis Based Allele-Specific Expression Detection, MBASED - Package containing functions for ASE analysis using Meta-analysis Based Allele-Specific Expression Detection 2026-02-14 02:00:17 17
pymzML
 
Resource Report
Resource Website
10+ mentions
pymzML (RRID:SCR_002500) software resource Python module to parse mzML data in Python based on cElementTree. It is an extension to Python that offers (i) an easy access to mass spectrometry (MS) data that allows the rapid development of tools, (ii) a very fast parser for mzML data and (iii) a set of functions to compare or handle spectra., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: mzML
has parent organization: University of Munster; North Rhine-Westphalia; Germany
PMID:22302572 Free, Available for download, Freely available biotools:pymzml, OMICS_03355 https://bio.tools/pymzml SCR_002500 2026-02-14 02:00:17 18
ESTHER
 
Resource Report
Resource Website
100+ mentions
ESTHER (RRID:SCR_002621) ESTHER data or information resource, database Database and tools for analysis of protein and nucleic acid sequences belonging to superfamily of alpha/beta hydrolases homologous to cholinesterases. Covers multiple species, including human, mouse caenorhabditis and drosophila., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. alpha hydrolase, beta hydrolase, cholinesterase, protein, protein superfamily, blast, gene, protein binding, protein-protein interaction, nucleotide, nucleotide sequence, enzyme, genetics, genome, genomics, mutation, disease, gene expression, peptide, chromosome is listed by: re3data.org
is related to: UniProtKB
is related to: AceDB
has parent organization: INRA - French National Institute for Agricultural Research; Paris; France
PMID:23193256 Free, Available for download, Freely available nif-0000-30526, SCR_008479, nif-0000-02817, r3d100010542 https://doi.org/10.17616/R33K77 SCR_002621 ESTerases and alpha/beta-Hydrolase Enzymes and Relatives, ESTHER Database, ESTerases and alpha / beta-hydrolase Enzymes and Relatives 2026-02-14 02:00:18 134
University of Auckland; Auckland; New Zealand
 
Resource Report
Resource Website
1+ mentions
University of Auckland; Auckland; New Zealand (RRID:SCR_002615) university Public university in New Zealand that offers degrees in areas such as the arts, business, education, medical and health science, and law. public university system, new zealand, degree program is related to: University of Auckland Biomedical Imaging Research Unit Molecular Devices ImageXpress Micro XLS
is parent organization of: CellML
is parent organization of: BEAST2
is parent organization of: ApiNATOMY
Free nlx_28115 SCR_002615 2026-02-14 02:00:18 2
Triangle BioSystems
 
Resource Report
Resource Website
10+ mentions
Triangle BioSystems (RRID:SCR_002603) TBSI commercial organization THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. A biomedical device company focused on developing and manufacturing neural hardware solutions for application in medical research using animals when bio-monitoring, recording and stimulation functions are needed. * Neural Recording Equipment * Neural Stimulation Equipment * Data Acquisition Hardware and Software computational neuroscience, eeg, eeg, meg, electrocorticography, hardware, other software resource, physiological recording, software is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) THIS RESOURCE IS NO LONGER IN SERVICE nlx_156006 http://www.nitrc.org/projects/tbsi SCR_002603 Triangle BioSystems International 2026-02-14 02:00:28 11
TetraMetrix
 
Resource Report
Resource Website
1+ mentions
TetraMetrix (RRID:SCR_002601) TetraMetrix software resource An open-source software project for distributed Tetrahedral Mesh Modeling and Analysis (TMMA) of multidimensional data. Tetrahedra are 3D, space filling, geometric objects that can be used to form representations and partitions of objects like volumes and shapes obtained from biomedical images (e.g., 3D MRI brain images). Tetrahedra are a natural extension of lines (1D) and surface triangulations (2D) which enable finite element analysis of irregular shapes, and permit a greater range of morphometric characterization of multidimensional objects. A beta version of the program is available for download. Please see the very brief instructions on the "Docs" tab on the left. magnetic resonance, 3d, mri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Laboratory of Neuro Imaging
Free, Available for download, Freely available nlx_156004 SCR_002601 2026-02-14 02:00:27 1
University of Athens; Athens; Greece
 
Resource Report
Resource Website
1+ mentions
University of Athens; Athens; Greece (RRID:SCR_002607) UoA university Public university in Athens, Greece that offers degree programs in health sciences, law and economics, and theology. public university in greece is related to: EARIP
is related to: ORBITO
is related to: International AMD Genetics Consortium
is parent organization of: Digital Repository Infrastructure Vision for European Research
is parent organization of: University of Athens Biophysics and Bioinformatics Laboratory
Free ISNI:0000 0001 2155 0800, grid.5216.0, Wikidata:Q547867, Crossref funder ID:501100005187, nlx_94434 https://ror.org/04gnjpq42 SCR_002607 University of Athens, National and Kapodistrian University of Athens 2026-02-14 02:00:28 4
Open Journal Systems
 
Resource Report
Resource Website
1+ mentions
Open Journal Systems (RRID:SCR_002642) OJS software resource Open source software made freely available to journals worldwide for the purpose of making open access publishing a viable option for more journals, as open access can increase a journal's readership as well as its contribution to the public good on a global scale. OJS assists with every stage of the refereed publishing process, from submissions through to online publication and indexing. Through its management systems, its finely grained indexing of research, and the context it provides for research, OJS seeks to improve both the scholarly and public quality of refereed research. OJS Features # OJS is installed locally and locally controlled. # Editors configure requirements, sections, review process, etc. # Online submission and management of all content. # Subscription module with delayed open access options. # Comprehensive indexing of content part of global system. # Reading Tools for content, based on field and editors' choice. # Email notification and commenting ability for readers. # Complete context-sensitive online Help support. journal management, publishing system, publication is listed by: FORCE11 Free, Available for download, Freely available nlx_156071 SCR_002642 2026-02-14 02:00:18 1
PeptideShaker
 
Resource Report
Resource Website
100+ mentions
PeptideShaker (RRID:SCR_002520) software resource Software providing a search engine independent platform for visualization of peptide and protein identification results from multiple search engines, currently supporting X!Tandem, MS-GF+, MS Amanda, OMSSA, MyriMatch, Comet, Tide, Mascot and mzIdentML. By combining the results from multiple search engines, while re-calculating PTM localization scores and redoing the protein inference, PeptideShaker attempts to give you the best possible understanding of your proteomics data. standalone software, proteomics, mass spectrometry, java, search engine, omssa, xtandem, mascot, ms-gf, msamanda, myrimatch, comet, tide is listed by: OMICtools
is related to: MS Amanda
has parent organization: Google Code
PMID:34709836 Free, Available for download, Freely available OMICS_03347 http://peptide-shaker.googlecode.com SCR_002520 2026-02-14 02:00:26 160
Memento
 
Resource Report
Resource Website
10+ mentions
Memento (RRID:SCR_002634) Memento software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. An extension for Chrome to see a version of a resource as it existed at some date in the past, by entering that URI in your browser and by specifying the desired date in a browser plug-in. Or you can actually browse the Web of the past by selecting a date and clicking. Whatever you land upon will be versions of Web resources as they were around the selected date. (This will only work if previous versions are available somewhere on the Web.) versioning, chrome, firefox, bookmarklet is listed by: FORCE11
has parent organization: Los Alamos National Laboratory
has parent organization: Old Dominion University; Virginia; USA
Library of Congress THIS RESOURCE IS NO LONGER IN SERVICE nlx_156058 SCR_002634 2026-02-14 02:00:25 38
PennCNV
 
Resource Report
Resource Website
100+ mentions
PennCNV (RRID:SCR_002518) PennCNV software resource A free software tool for Copy Number Variation (CNV) detection from SNP genotyping arrays. Currently it can handle signal intensity data from Illumina and Affymetrix arrays. With appropriate preparation of file format, it can also handle other types of SNP arrays and oligonucleotide arrays. PennCNV implements a hidden Markov model (HMM) that integrates multiple sources of information to infer CNV calls for individual genotyped samples. It differs form segmentation-based algorithm in that it considered SNP allelic ratio distribution as well as other factors, in addition to signal intensity alone. In addition, PennCNV can optionally utilize family information to generate family-based CNV calls by several different algorithms. Furthermore, PennCNV can generate CNV calls given a specific set of candidate CNV regions, through a validation-calling algorithm. imaging genomics, copy number variation, snp, genotyping array, array, oligonucleotide, hidden markov model, genotype, genome is listed by: OMICtools
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: VegaMC
is related to: OpenBioinformatics.org
has parent organization: University of Pennsylvania; Philadelphia; USA
NIMH MH604687 PMID:17921354 Free OMICS_00729, nlx_155921 http://www.openbioinformatics.org/penncnv/
http://www.neurogenome.org/cnv/penncnv SCR_002518 PennCNV: copy number variation detection 2026-02-14 02:00:26 349
OEI fMRI compatible olfactometer
 
Resource Report
Resource Website
1+ mentions
OEI fMRI compatible olfactometer (RRID:SCR_002507) OEI fMRI compatible olfactometer instrument resource A computerized, odor delivery device that can be used for basic research applications including mapping olfactory centers, cognitive / learning research, neuro-marketing among other uses. Additional products including tests for odor threshold, odor identification, odor discrimination and odor memory. experiment control, hardware, magnetic resonance, stimulus presentation, odor, olfactory, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial License nlx_155907 http://www.nitrc.org/projects/oei
http://www.osmicenterprises.com/docs/OsmicFMRIOlfactomterManual%207-1-13.pdf
SCR_002507 2026-02-14 02:00:26 4

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