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https://biointerfaces.umich.edu/facility/nanotechnicum/

Nanotechnicum is a Biointerfaces Institute core facility providing Nanoparticle Size analysis and Zeta Potential characterization, Chiral materials spectroscopy, Material Pore Size and Porosity characterization, Materials Thermal analysis, and Biomolecular Binding characterization instrumentation and services. The Biointerfaces Institute offers instrumentation to the University of Michigan’s research community, fellow academic institutions, and industry.

Proper citation: University of Michigan Biointerfaces Institute Nanotechnicum Core Facility (RRID:SCR_026717) Copy   

•   Source: SciCrunch Registry

https://pharmacy.umich.edu/research-and-practice/research-cores/biochemical-nuclear-magnetic-resonance/

Provides full-service consultation, sample processing and results. After running your samples, we will process your data using Mestranova and give you access to the raw data via email or Dropbox.

Proper citation: University of Michigan College of Pharmacy Biochemical Nuclear Magnetic Resonance Lab Core Facility (RRID:SCR_026716) Copy   

•   Source: SciCrunch Registry

https://sites.lsa.umich.edu/bio-mass-spec/

Facility provides specialized MS services. The major areas of focus of the lab are Analysis of intact proteins, multi-protein complexes, and protein structure; Identification and purification of compounds from complex mixtures coupled with quantitative analysis.; Purification using mass directed autopurification liquid chromatography. Users can be trained on the instruments for walk-up use or samples can be submitted for analysis.

Proper citation: University of Michigan Biological Mass Spectrometry Core Facility (RRID:SCR_026718) Copy   

•   Source: SciCrunch Registry

https://lsa.umich.edu/rmc/resources/ct-scanner.html

Core allows researchers to generate high resolution tomographic data of bone, fossils, and contrast enhanced tissues. These data can include 3D surface visualizations of anatomy and morphology, that can facilitate morphometric studies, phylogenetics analysis, and biomechanics modelling.

Proper citation: University of Michigan MicroCT Scanning Laboratory Core Facility (RRID:SCR_026773) Copy   

•   Source: SciCrunch Registry

https://morphomicanalysisgroup.org/index.html

Core identifies bio-markers using medical imaging that provides insight into disease processes, treatment options, and outcome variability.

Proper citation: University of Michigan Morphomic Analysis Core Facility (RRID:SCR_026774) Copy   

•   Source: SciCrunch Registry

https://diabetes.med.umich.edu/partners/michigan-diabetes-research-center-mdrc/cores/clinical/chemistry-laboratory

Core supports investigators interested in assays related to diabetes, heart disease, and hypertension. Analytical methods include general blood chemistry, chemiluminescence, immunoassay, radioimmunoassay, multiplexing, and ELISA.

Proper citation: University of Michigan MDRC Chemistry Laboratory Core Facility (RRID:SCR_026768) Copy   

•   Source: SciCrunch Registry

https://lsa.umich.edu/mcdb/resources/mcdb-imaging-facility.html

MCDB Imaging Facility in the Biological Sciences Building provides microscopes available to any University of Michigan researcher. Access to scope time granted after appropriate training. Provides microscope equipment, image capture systems, software to assist researchers with their sample imaging.

Proper citation: University of Michigan LSA MCDB Imaging Core Facility (RRID:SCR_026767) Copy   

•   Source: SciCrunch Registry

https://primate.wisc.edu/homepage/our-services/animal-services/pathology-services/

Pathology Services Core is essential to nonhuman primate colony health and research at the WNPRC. PSU team consists of pathologists with ACVP and/or ACLAM board certification, research program manager, and research specialists. Unit works with clinical veterinary staff to provide rapid diagnosis and effective monitoring and interpretation of acute and chronic conditions affecting colony animals as well as subjects assigned to research studies. Core offers services including clinical pathology testing; cytology evaluation; surgical biopsy evaluation; gross post mortem examination, specialized sample collections; and histology with unbiased interpretation of lesions in reference to spontaneous disease, experimental questions, and research goals. PSU is responsible for collection, banking, and distribution of NHP samples through both Nonhuman Primate Biological Materials Distribution core and National Institute on Aging Nonhuman Primate Tissue Bank.

Proper citation: Wisconsin National Primate Research Center Pathology Services Core Facility (RRID:SCR_026782) Copy   

•   Source: SciCrunch Registry

https://www.waisman.wisc.edu/idd-models/

Models Core in Waisman Center provides resources including mouse models of human conditions, along with behavioral testing capabilities to characterize these models and test new therapies; stem cell technologies to support creation of induced pluripotent stem cell lines for IDD conditions as well as specialized genome editing services; microscopy technology and expertise for characterization of both stem cell and mouse models of IDD conditions.

Proper citation: University of Wisconsin-Madison Intellectual and Developmental Disabilities Models Core Facility (RRID:SCR_026781) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/electronics/

Electronics Core is electronics design, development and repair facility which specializes in proof-of-concept design and prototyping, and early stage development of medical devices and laboratory research instrumentation. Services include system design, schematic capture, printed circuit board layout, board fabrication, assembly and testing.

Proper citation: Cleveland Clinic Lerner Research Institute Electronics Core Facility (RRID:SCR_026870) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/lifesciences-faculty/laboratory-molecular-cell-biology/research/platforms-and-facilities/light-microscopy

Core provides imaging systems for advanced microscopy including confocal, multi-photon and super-resolution modalities, enabling users to address research questions in living systems across temporal and spatial scales. Staff offers training to use equipment, expertise about experimental strategy, design, image processing and analysis.

Proper citation: University College London Light Microscopy Imaging Core Facility (RRID:SCR_026871) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/functional-genomics-screening-unit.php

Core specializes in high-throughput CRISPR screening using pooled or arrayed libraries in diverse cellular models. This technology assesses the effects of thousands of genetic perturbations at single-cell resolution with CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa). It also utilizes base and prime editing to investigate specific mutations, such as those relevant to cancer development and progression.

Proper citation: Cancer Research Institute IFOM FGS Functional Genomic Screening Core Facility (RRID:SCR_026867) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/imaging.php

Core Facility provides technological platforms in the field of light microscopy. A team of highly qualified and experienced professionals supports IFOM's research activities, assisting in sample preparation and acquisition, data post-processing and image analysis.

Proper citation: Cancer Research Institute IFOM ALM Advanced Light Microscopy Core Facility (RRID:SCR_026866) Copy   

•   Source: SciCrunch Registry

https://syntheticbiology.northwestern.edu/research/biofoundry/

Core facility for synthetic biology experimentation including pilot-scale fermentation, high throughput automation, biological sample analysis, and cell-free protein synthesis.

Proper citation: Northwestern University SynBio Foundry Core Facility (RRID:SCR_026869) Copy   

•   Source: SciCrunch Registry

https://facs.iq.msu.edu/

Core provides access to analytical flow cytometry instrumentation and cell sorting services, as well as training and experimental consultation.

Proper citation: Michigan State University Flow Cytometry Core Facility (RRID:SCR_026903) Copy   

•   Source: SciCrunch Registry

https://medresearch.umich.edu/office-research/about-office-research/our-units/central-biorepository

Core provides annotated biospecimens for basic, clinical, and translational research. Helps researchers access, collect, manage, and protect biospecimens using automated processes and quality control. Offers safe and monitored management of biospecimens including temperature-controlled storage, preparation of derivatives from these specimens, aliquoting, distribution, and production of specimen collection kits.

Proper citation: University of Michigan Medical School Central Biorepository Core Facility (RRID:SCR_026845) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/biorobotics/

Core provides biomechanical testing of biological structures and biomaterials. Allows investigators to conduct research of mechanical properties of existing biological structures and constructs, as well as to quantify potential for new technologies and clinical advancements. Robotic simulators are built around the simVITRO software platform and are designed for in vitro simulation of major joints including knee, spine, foot, ankle, hip, shoulder, elbow, wrist and more. Provides testing capabilities for range of biomechanical modalities and will offer expert advice and support for development of new test protocols, innovative techniques for instrumentation and data collection. Modalities include tissues, joints, and multi-articular units, such as foot or spine segments.

Proper citation: Cleveland Clinic Lerner Research Institute BioRobotics and Mechanical Testing Core Facility (RRID:SCR_026849) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/eppley/cmtdd/cores/scst.html

Core offers spatial omics processing on many different tissue types. Facility provides instrumnets including Bruker's GeoMx DSP ready for launch with anticipated launch of 10x Visium. Offers expert collaboration from project design to data handoff. Core has established workflows with additional shared resources on UNMC campus to allow for expertise throughout entire project.

Proper citation: University of Nebraska Medical Center Single Cell and Spatial Transcriptomics Core Facility (RRID:SCR_026860) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/electron-microscopy.php

Core performs routine transmission and scanning Electron Microscopy and all kinds of immune Electron Microscopy, correlative light electron microscopy, three-dimensional EM (3DEM), quantitative stereological evaluation of data and more.

Proper citation: Cancer Research Institute IFOM EMCT Electron Microscopy Cells & Tissues Core Facility (RRID:SCR_026863) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/mechanomedicine.php

Core focuses on development of innovative biomedical technologies and devices for cancer research as well as biomedical applications using microfabrication and 3D printing.

Proper citation: Cancer Research Institute IFOM CERD Cancer Engineering R&D Core Facility (RRID:SCR_026862) Copy   

•   Source: SciCrunch Registry