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https://bsp.web.unc.edu/

Centralized, quality controlled facility and biorepository for processing, storage and disbursement of human specimens.Offers high throughput processing of human biospecimens, with specific emphasis on DNA and RNA isolation and purification.Provides laboratory support for investigator initiated large scale clinical, epidemiologic, and other studies.Functions as human specimen biorepository resource for clinicians who wish to store and study samples from unusual or potentially important patients.Biorepository is managed by custom LIMS, with sample accessioning, tracking and audits at each step.Provides scientific resource for investigators seeking advice or consultation on study design including specimen collection and storage methods, and human subject issues. Core staff act as liaison to other UNC core facilities and outside collaborators.

Proper citation: University of North Carolina at Chapel Hill Biospecimen Processing Core Facility (RRID:SCR_021290) Copy   

•   Source: SciCrunch Registry

https://pennstatehealthnews.org/topics/cryo-em/

Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.

Proper citation: Penn State Hershey College of Medicine cryo-EM Core Facility (RRID:SCR_021178) Copy   

•   Source: SciCrunch Registry

http://dnaseq.med.harvard.edu

Core offers high throughput Sanger sequencing for any number of samples with 24 hour turn around time,PCR cleanups and mini-preps as well as sample prep from colonies or pellets.Provides large plasmid repository with over 300,000 constructs.Provides ORFs from MGC, Yeast, Xenopus, Drosophila, mouse, as well as several many other organisms including bacterial species. Accept deposits.

Proper citation: Harvard Medical School DNA Resource Core Facility (RRID:SCR_021292) Copy   

•   Source: SciCrunch Registry

https://cancer.dartmouth.edu/scientists-researchers/molecular-biology-resource

Genomics Section provides services and instrumentation that enable DNA/RNA extraction and quality control, next-generation Illumina and Nanopore sequencing, epigenetic profiling, and microarray analysis on a whole-genome scale, from the level organisms to single cells. Molecular Biology Section provides DNA fragment analysis qPCR, Sanger sequencing and NanoString Technology.

Proper citation: Dartmouth Genomics and Molecular Biology Shared Resource (GMBSR) (RRID:SCR_021293) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/compchem/index.html

Core offers wide variety of services, including access to the Schrodinger platform and high-throughput computing. Services include examining molecular structures and mechanisms in atomic detail and provide graphically rich analysis suitable for inclusion in publications and grants.

Proper citation: University of Nebraska Medical Center Computational Chemistry Core Facility (RRID:SCR_021023) Copy   

•   Source: SciCrunch Registry

https://miap.eu/miap-unit/life-imaging-center/

Central core facility open to members of all faculties and the university clinic. Consists of 14 rooms in the Center for Integrative Signalling Analysis with 9 microscopy rooms with 20 microscope set-ups (3D-STED, confocal FLIM, two 2-photon confocal microscopes, 4 conventional confocal microscopes, lightsheet microscope, 4 high-end widefield ratio-imaging set-ups, 4 fluorescence stereo microscopes, 3 special set-ups for screening. LIC microscopes are hosted in Biosafety level S2 and S1 environments, connected to a large wet lab area and a cell culture room, both Biosafety level S2 classified. Additionally, the LIC offers a large computer lab with 12 high-end workstations for image processing and analysis. The LIC also covers two additional rooms, hosting 3 LSM systems in a neighboring building of the Signalling Campus Freiburg (SCF).

Proper citation: University of Freiburg Life Imaging Center Core Facility (RRID:SCR_020968) Copy   

•   Source: SciCrunch Registry

https://www.cityofhope.org/patients/departments-and-services/pathology

Department of Pathology at City of Hope combines state-of-the-art laboratories equipped with the latest diagnostic techniques and advanced instrumentation with superior investigative skills to accurately and rapidly identify even the rarest and most complex diseases. Our experts provide comprehensive services, from initial diagnosis to monitoring of prognostic indicators throughout the treatment process.

Proper citation: City of Hope Department of Pathology Core Facility (RRID:SCR_020974) Copy   

•   Source: SciCrunch Registry

http://www.bioimaging.ubc.ca

Provides optical and electron microscope infrastructure for live cell imaging, multi photon imaging, advanced sample preparation including cryo-preparation for electron microscopy, routine SEM and TEM, Cryo-TEM, TEM tomography, and Correlative Light and Electron Microscopy (CLEM). Equipped with 4 electron microscopes (1 SEM and 3 TEMs), 2 advanced fluorescence microscopes (confocal/multi-photon and spinning disk), cryo-fixation (High pressure freezer, Vitrobot) and EM processing equipment (Microwave, critical point dryer, coaters).Provides microscopy access, training and service.

Proper citation: University of British Columbia Vancouver Bioimaging Core Facility (RRID:SCR_021304) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/light-microscopy

Core provides resources for imaging model organisms, tissue, cells, biomaterials, and artificial structures and houses equipment including almost every light microscopy imaging modality presently available. Cell culture facilities are also available nearby as well as other routine items necessary for biological imaging and material imaging. This facility has been designated Nikon Centers of Excellence, thus providing unique opportunity for training, demonstration, instrument development, and research.We excel in use of telemicroscopy through use of remote imaging sessions, remote control of all instruments, and remote data analysis sessions available to all users.Provides training to all users that plan to conduct experimentation. Following an initial consultation in which experimental requirements, expected outcomes, and careful scrutiny of feasibility, training and/or access is arranged through the Director.

Proper citation: University of Massachusetts Light Microscopy Core Facility (RRID:SCR_021148) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/cemrc/

Offers new cryo-electron microscopy tools available to University researchers, allowing for visualization of three-dimensional structures of molecules and macromolecular complexes in solution.

Proper citation: Rockefeller University Cryo Electron Microscopy Resource Center Core Facility (RRID:SCR_021146) Copy   

•   Source: SciCrunch Registry

https://www.bmh.manchester.ac.uk/research/facilities/electron-microscopy/

Offers expertise and equipment tailored for biological samples mostly. Houses four electron microscopes.Preparation laboratory includes range of specialised room temperature and cryo sample preparation equipment, ultramicrotomes and suite of computer workstations for image processing.Electron microscopy staff are available to train and assist.

Proper citation: University of Manchester Electron Microscopy Core Facility (RRID:SCR_021147) Copy   

•   Source: SciCrunch Registry

https://htrc.uchicago.edu

Coordinated, centralized, and dedicated program for procuring, processing, dispersing and assessing all types of biospecimens together with downstream histology services. CAP Accredited.

Proper citation: University of Chicago Human Tissue Resource Center Core Facility (RRID:SCR_019199) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/confocal/

Offers microscopy imaging, including bright field color and DIC, fluorescence multi-dimension,TIRFM including bleaching, ablation, FLIM and high resolution, highspeed, high sensitivity, confocal, and physiologic techniques, STED, GSD3D, lightsheet selective plane illumination and lattice lightsheet structured illumination super resolution microscopy.

Proper citation: University of Chicago Integrated Light Microscopy Core Facility (RRID:SCR_019197) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/cryo-electron-microscopy-laboratory/

Shared resource hosting advanced cryo–electron microscopes fitted with direct detectors as well as equipment for sample preparation.

Proper citation: New York University School of Medicine Langone Health Cryo-Electron Microscopy Laboratory Core Facility (RRID:SCR_019202) Copy   

•   Source: SciCrunch Registry

https://www.uvm.edu/research/imf

Core specializes in design and development of prototypes to advance research. Design engineers complete product development in Solidworks and testing in Labview. Machine shop exists to turn variety of materials into functional prototypes.

Proper citation: University of Vermont Innovate Model Fabricate Labs Core Facility (RRID:SCR_021355) Copy   

•   Source: SciCrunch Registry

https://www.chemistry.ucsc.edu/research/facilities/index.html

Shared research facility dedicated to improving human health by finding next generation of therapeutic agents against wide variety of diseases. The CSC is driving innovation in drug discovery by bringing together experts in drug screening with cell and molecular biologists engaged in disease research. Has assembled diverse collection of compounds derived from marine organisms, setting our facility apart as a leader in the discovery of therapeutic natural products.

Proper citation: University of California, Santa Cruz Chemical Screening Center Core Facility (RRID:SCR_021114) Copy   

•   Source: SciCrunch Registry

https://www.centreforbrainhealth.ca/biobank

Centralized resource for collection, storage, and distribution of pre and post mortem biospecimen and tissue at Djavad Mowafaghian Centre for Brain Health.Biobank facility also provides vast range of specimen processing and storage services to other research groups.

Proper citation: University of British Columbia Borgland Brain DNA and Tissue Bank Core Facility (RRID:SCR_021356) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/flow-cytometry/

Offers Flow Cytometry analysis, Cell sorting, Flow Imaging analysis.Available cytometers include 4-color BD FACSCalibur,10-color BD FACSCanto 10-color Amnis ImageStream X Mk II imaging cytometer,Special-order 16-color BD LSR II,16-color BD LSR Fortessa,17-color BD FACS Aria SORP high-performance cell sorter,23-color BD FACSSymphony.

Proper citation: Penn State Hershey College of Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_021134) Copy   

•   Source: SciCrunch Registry

https://research.utk.edu/oried/core-facilities/bsmmsc/

Mass Spectrometry Core provides metabolomics, lipidomics, and small molecule analyses to researchers both on campus and in our affiliated local and other institutions.

Proper citation: University of Tennessee Knoxville Biological and Small Molecule Mass Spectrometry Core Facility (RRID:SCR_021368) Copy   

•   Source: SciCrunch Registry

http://bcm.edu/oivm

Core provides instrumentation, imaging and image analysis tools.Ddicated to vital and intravital imaging of cellular processes within cells, intact tissue explants, developing embryos and functioning organs within the live animal. Our users are focused on a variety of applications such as understanding cell migration, optimizing angiogenic therapies, how blood flow influences development and cancer, immune cell recruitment, stem cell-niche interactions and cancer metastasis.

Proper citation: Baylor College of Medicine Optical Imaging and Vital Microscopy Core Facility (RRID:SCR_019297) Copy   

•   Source: SciCrunch Registry