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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core facility is equipped with instrumentation to support proteomic and metabolomic research, as well as equipment for materials characterization. Key instruments include a Bruker 700MHz NMR, two Bruker XRDs (Powder and Crystal), and Bruker Micro ToF mass spectrometer.
Proper citation: Claflin University Molecular Science Research Center Core Facility (RRID:SCR_018836) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_041850.pdf
Automated peptide synthesizer for chain assembly steps in solid phase peptide synthesis or FastMoc chemistry. Data is based on conductance or ultraviolet UV absorbance of reagent, solutions, and solvents in the synthesis cycle.
Proper citation: Applied Biosystems 433A Peptide Sequencer (RRID:SCR_018440) Copy
http://www.umass.edu/ials/mass-spectrometry
Core offers instrumentation for characterizing elements and compounds across the entire mass range. Specialized mass spectrometers encompass variety of ionization techniques and separation devices to cover wide range of analytical capabilities.Facility accepts samples and will perform requested analysis.Offers training to conduct experimentation. Instruments include Bruker SolariX FT-ICR,Bruker MicroTOF II ESI,Bruker MicroFLEX MALDI,JEOL MStation sector with EI and FAB sources.
Proper citation: UMass Amherst Mass Spectrometry Core Facility (RRID:SCR_019063) Copy
http://www.pasteur.fr/biophysics
Provides services and instrumentation for characterization of biological macromolecules with technical and methodological expertise. Provides characterization of macromolecules including shape, folding, stability auto-association,and they interactions including stoichiometry,thermodynamic and kinetic parameters.
Proper citation: Pasteur Institute Biophysics of Macromolecules and their Interactions Core Facility (RRID:SCR_018267) Copy
Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.
Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy
https://animalcare.umich.edu/business-services/ulam-pathology-core/
Our core is affiliated with the Unit for Laboratory Animal Medicine (ULAM) at the University of Michigan-Ann Arbor. We provide animal pathology services in support of non-GLP preclinical, translational, or basic science studies. Services include histology preparation, immunohistochemistry, animal hematology and serum chemistry assays, digital slide scanning/image analysis, and pathology interpretation by board-certified veterinary pathologists. Our core mission is to reduce bias and increase rigor within non-GLP animal research by providing high quality, documented, pathology support that may not be otherwise accessible within individual laboratories. Our laboratory maintains internal SOPs, documented quality control practices, and accountability/chain-of-custody records for all submissions. Additionally, we participate in an external quality control program through the Veterinary Laboratory Association.
Proper citation: University of Michigan ULAM Pathology Core Facility (RRID:SCR_018823) Copy
https://childrenshospital.corefacilities.org/service_center/show_external/3145
Core with advanced instrumentation in Light and Electron Microscopy.Core provides confocal, multiphoton microscopy,electron microscopy,image analysis.
Proper citation: Harvard Medical School PCMM Microscopy Core Facility (RRID:SCR_018822) Copy
Assists researchers and clinicians with molecular and morphologic characterization of normal and disease tissues of interest in support of biomarker discovery and translational research. Offers both routine and advanced histology immunohistochemistry, in situ and whole slide scanning services.
Proper citation: New York University School of Medicine Center for Biospecimen Research and Development Histology Core Facility (RRID:SCR_018304) Copy
Core helps researchers investigate interactions between small molecules and biological systems by providing medicinal chemistry and chemical biology expertise and organic synthesis support.
Proper citation: Oregon Health and Science University Medicinal Chemistry Core Facility (RRID:SCR_019048) Copy
https://dentistry.musc.edu/research/gcohr
Core offers investigators opportunity to address research questions that require use of gnotobiotic animals. Standard services provide germ free mice (e.g. BALB/c, C57BL/6), deriving new strains of mice into germ free state by caesarean section, tissue collection and/or fluid from mice that have not received treatment or manipulations, exporting germ free mice in sterile transporters to other institutions. Non-Standard Services include maintaining and breeding newly derived germ free mice, administration of specialized diets, administration of compounds as therapeutic or disease-inducing agents, tissue collection and/or fluid from mice that have received treatment or manipulations.
Proper citation: Medical University of South Carolina College of Dental Medicine Gnotobiotic Animal Core Facility (RRID:SCR_018884) Copy
https://www.colorado.edu/lab/biocore/
Purpose is to connect MCDB, EBIO, and IPHY researchers to campus research resources.
Proper citation: University of Colorado Boulder BioCore Core Facility (RRID:SCR_019302) Copy
Fully equipped (U-Th)/He thermochronology facility.
Proper citation: University of Colorado Boulder CU Thermochronology Research and Instrumentation Lab Core Facility (RRID:SCR_019303) Copy
Designed to measure relative abundance of stable isotopes of light elements and molecules.
Proper citation: University of Colorado Boulder Earth Systems Stable Isotope Lab Core Facility (RRID:SCR_019300) Copy
https://www.coresri.org/facilities?facility_id=16
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Core offers contemporary imaging, molecular biology, histology, flow cytometry, cell sorting, and real-time gene expression. Provides technologies and training including specialized microscope facility.
Proper citation: Brown Alpert Medical School Women and Infants Hospital of Rhode Island Kilguss Research Institute Molecular Biology and Imaging Core Facility (RRID:SCR_021348) Copy
https://research.med.psu.edu/core-facilities/transmission-electron-microscopy/
Provides consultation and training in TEM imaging of biological, chemical, and materials science samples.
Proper citation: Penn State Hershey College of Medicine Transmission Electron Microscopy Core Facility (RRID:SCR_021200) Copy
https://mcgill.ca/cftrc/platforms/primary-airway-cell-biobank-pacb
Nonprofit facility providing researchers worldwide with standardized, high-quality primary airway cells from normal and large variety of airway diseased donors with different genetic backgrounds, are essential for improving our understanding of CF and other respiratory diseases and for translational research to develop new therapeutic agents.The PACB is certified by the UBC Office of Biobank Education and Research Biobank Certification Program.
Proper citation: McGill University Primary Airway Cell Biobank Core Facility (RRID:SCR_020998) Copy
https://www.feinberg.northwestern.edu/sites/cam/
Core offers instrumentation and services for study of biological processes at whole animal, tissue, cellular and subcellular levels. Services include electron microscopy, super resolution microscopy, fluorescent laser scanning and spinning disk microscopy, fluorescent lifetime imaging, automated high throughput tissue cytometry, atomic force microscopy, laser capture microdissection, mutliphoton imaging, and whole animal bioluminescent and fluorescent imaging. Additionally we provide microinjection equipment, chambers for stable live cell observation, and anesthesia equipment. Provides training on numerous different instrument platforms, consultation on experiment design, as well as digital image processing and image analysis. We are a reference site for several companies including TissueGnostics. CAM is one of three Nikon Imaging Centers in the US, allowing us access and excellent support from Nikon to develop innovative solutions for the cutting edge imaging needs of users. This relationship has allowed our users to push super-resolution technologies to permit multi-color, 3D and live-cell applications. Additionally, we have been working together with Nikon to add confocal laser scanning to a low magnification upright dissection microscope, which is particularly useful to researchers interested in visualizing thick samples (such as epidermal raft cultures) at increased cellular resolution. We are also currently expanding our full service electron microscopy offerings. We currently support TEM and SEM sample preparation, immunogold labeling, platinum replicas, and CLEM.
Proper citation: Northwestern University Feinberg School of Medicine Center for Advanced Microscopy Nikon Imaging Center Core Facility (RRID:SCR_020996) Copy
Center composes network of core imaging facility locations for advanced optical imaging and basic electron microscopy located within the AHC/Medical School (1-151 Jackson Hall, Minneapolis) and College of Biological Sciences (23 Snyder Hall, St. Paul) on the University of Minnesota Twin Cities Campus.UIC cores serve internal and external research clients in design of imaging experiments, choice of and training on suitable imaging systems, and subsequent image processing, visualization and analysis.Provides advanced imaging systems including macro spectral confocal microscopy,wide-field light and fluorescence microscopy, spinning disk confocal, laser-scanning confocal microscopes, multi photon/Second Harmonic Generation microscopes, total internal reflectance microscope, laser capture micro-dissection, live cell imaging systems, scanning and transmission electron microscopy, whole animal fluorescence, bioluminescence and chemiluminescence imagers, gel, print and film scanners,poster printers, full sample preparation capabilities.
Proper citation: University of Minnesota University Imaging Centers Core Facility (RRID:SCR_020997) Copy
https://medicine.tamu.edu/imil
Core supports research progress and grant development by encouraging researchers to explore advanced imaging modalities and to incorporate them into their existing research programs.Provides technical expertise and cutting edge microscope systems to support research of faculty and staff of Texas A&M University Health Science Center, Texas A&M University, and all other campuses.IMIL includes six microscopy rooms, supporting facilities, and image processing station.Technical staff is available to train and assist with design, implementation, and analysis of experiments as well as assist in troubleshooting.
Proper citation: Texas A&M Health Science Center Integrated Microscopy and Imaging Laboratory Core Facility (RRID:SCR_021637) Copy
https://www.colorado.edu/chbe/instrument-shop
Provides mechanical and electrical design and fabrication services at CU Boulder.Provides solutions for instructional and research needs for any department or college. Collectively comprised of machine shop and electronics shop, both of which are located in basement level of Jennie Smoly Caruthers Biotechnology Building.
Proper citation: University of Colorado Boulder Chemical and Bio. Engineering instrument and electronics Core Facility (RRID:SCR_019298) Copy
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