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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.uab.edu/medicine/cysticfibrosis/about/cell-model-core
Core that assists with patch clamp and single channel analysis relevant to ion channel gating. The core also provides primary murine airway epithelial cells.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cell Model and Evaluation Core (RRID:SCR_015395) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mucuscore
Core that provides a service to quantify the concentration of given mucus samples for both total mucus concentration and the absolute relative contributions of each secreted mucin. It also provides quantitation of extracellular DNA. The mucus biphysics subcore component, provides core users with information on the biophysical properties of the mucus layer and its interaction with the cell surface.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mucus and Mucin Biochemistry and Biophysics Core (RRID:SCR_015393) Copy
http://www.umassmed.edu/umpc/cores/analytical/
Core that provides analysis of hormones, cytokines, chemokines, metabolites, and electrolytes across multiple platforms (serum, tissues, homogenates, and cells) as well as liver function analysis through instrumentation.
Proper citation: MMPC-University of Massachusetts Medical School Analytical Core (RRID:SCR_015365) Copy
http://www.uc.edu/labs/mmpc/select-test/lipid-metabolism.html
Core that provides services based on the testing and analysis of fat lipids, intestinal lipid absorption, and cholesterol in tissues.
Proper citation: MMPC-University of Cincinnati Medical Center Lipid Lipoprotein and Glucose Metabolism Core (RRID:SCR_015363) Copy
http://depts.washington.edu/cfrtc/clinical/
Core that aims to provide preclinical support for novel therapeutics, work with other biomedical cores to enhance and support bacterial and human specimen repositories, and support developmental research and training.
Proper citation: Cystic Fibrosis Center - University of Washington Clinical Core (RRID:SCR_015402) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=34
Core which provides services and facilities for stable, biocontainment housing, husbandry, and health care of mice. The Core manages transfer of mice from the user's institution and testing of mice for the quarantine process.
Proper citation: MMPC-University of Massachusetts Medical School Animal Care Core (RRID:SCR_015368) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=45
Core responsible for oversight and coordination of all aspects of the scientific and administrative operations of the MMPC-UCD. This includes providing full customer support services, overseeing management and operation of the Center, and foster interactions and synergism among cores and research projects. The ultimate goal of the Core is to ensure that the Center effectively and efficiently delivers services to its users.
Proper citation: MMPC-University of California Davis Administrative Core (RRID:SCR_015362) Copy
http://sph.unc.edu/norc/research-partnerships/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 23,2019. Center that provides bioinformatics and metabolomics support to UNC members for nutrition and obesity-related clinical and translational research.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Research Facilitation Program (RRID:SCR_015480) Copy
http://www.uc.edu/labs/mmpc/select-test/cardiovascular-services.html
Core that offers services in testing animal physiological variables such as blood pressure, heart rate, pulse pressure and activity after inserting a PA-C10 telemetry device in them.
Proper citation: MMPC-University of Cincinnati Medical Center Cardiovascular and Renal Function Core (RRID:SCR_015360) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/assay-core
Core that provides Ussing chamber capabilities and expertise for testing vectoral anion transport in polarized airway epithelial monolayers, and florescent dye-based methods for evaluating CFTR activity in cells grown on coverslips. The core also performs immunolocalization for proteins relevant to cystic fibrosis pathogenesis.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Assay Core (RRID:SCR_015407) Copy
http://depts.washington.edu/cfrtc/inflammation/
Core whose objective is to obtain information on relevant parameters of the host response that is unique to cystic fibrosis using a variety of techniques, including in vivo and in vitro imaging, immunohistochemistry, imaging and image analysis, cells and bacteria in tissues, and quantification of chemokines, cytokines, and other factors with ELISA.
Proper citation: Cystic Fibrosis Center - University of Washington Host Response Core (RRID:SCR_015405) Copy
http://depts.washington.edu/cfrtc/administrative-core/
Core that manages and oversees the UW CFRTC and its cores and pilot and feasibility programs.
Proper citation: Cystic Fibrosis Center - University of Washington Administrative and Enrichment Core (RRID:SCR_015408) Copy
http://umassmed.edu/umpc/cores/cardiovascular/
Core that provides phenotyping of cardiovascular system in mouse models of metabolic disease and an easily accessible cardiovascular disease model pipeline. It services include 2D and M-mode echocardiography in lightly-anesthetized mice to non-invasively assess cardiac structure and function using state-of-the-art high-frequency, high-resolution in vivo digital imaging platform as well as Transverse Aortic Constriction (TAC) model to investigate pressure-overload hypertrophy, congestive heart failure, and aortic stenosis.
Proper citation: MMPC-University of Massachusetts Medical School Cardiovascular Core (RRID:SCR_015375) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=50
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2025. Core whose mission is to provide analytical tools to investigators to permit determination of the structure of the microbiome in mouse models of disease and assistance in the cultivation of microbes that will permit hypothesis testing in murine models including the germfree animals that are available in the Animal Care Core.
Proper citation: MMPC-University of Michigan Medical School Microbiome Core (RRID:SCR_015378) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core
Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.
Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy
https://labnodes.vanderbilt.edu/resource/view/id/10820/community_id/1418
Core that consists of three subcores: Hormone Assay and Analytical Services, Lipids, Lipoproteins, and Atherosclerosis, and Mouse Pathology. The Hormone Assay and Analytical Services provides analyses that facilitate research in diabetic, cardiovascular, and obese animal models. Lipids and Lipoproteins Subcore provides quantitative and qualitative measurements of plasma and tissue lipids and lipoproteins to researchers who use mice to study atherosclerosis, dyslipidemia, diabetes, obesity, hypertension, and other metabolic diseases. Mouse Pathology services include standard pathology testing in hematology, clinical chemistry, parasitology, microbiology, serology, molecular diagnostics, necropsy, and research histology and pathology expertise and counseling.
Proper citation: MMPC-Vanderbilt University School of Medicine Analytical Resources Core (RRID:SCR_015379) Copy
http://www.uc.edu/labs/mmpc/select-test/energy-balance.html
Core that specializes in total body/carcass analysis, measurement of oxygen consumption and carbon dioxide production, meal pattern analysis, and feeding mass/bouts, drinking volume, VO2 and VCO2.
Proper citation: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core (RRID:SCR_015371) Copy
http://www.med.umich.edu/mgpc/cores/vivo.htm
Core facility that consists of the following 4 distinct programs: In Vivo Small Animal Studies Program, Organoid/Enteroid Modeling Program, Biospecimens Banking Service, and Clinical Design and Statistics.
Proper citation: University of Michigan Center for Gastrointestinal Research In Vivo Animal and Human Studies Core (RRID:SCR_015608) Copy
http://www.uchicagoddrcc.org/research-cores/tissue-and-cell-analysis-core
Core whose services include anatomic pathology review of human and experimental animal tissues as well as consultation in the best approaches for such analyses, cost-effective and high quality processing and staining of formalin-fixed paraffin-embedded tissues, and making collections of human tissue and imaging technologies available to researchers.
Proper citation: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core (RRID:SCR_015607) Copy
Ratings or validation data are available for this resource
A collaborative research project that supports nPOD approved diabetes investigators by freely providing rare and difficult-to-obtain tissues from type 1 and type 2 diabetes donors. Interested researchers are encouraged to apply to obtain nPOD tissues, or to request access to analyze cases in the nPOD Online Pathology site. Interested donors can contact nPOD directly for more information.
Proper citation: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641) Copy
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