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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GADMA
 
Resource Report
Resource Website
1+ mentions
GADMA (RRID:SCR_017680) GADMA software application, data processing software, data analysis software, software resource Software tool to implement methods for automatic inferring joint demographic history of multiple populations from genetic data. Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data. Inferring, demographic, history, population, genetic, data, allele, frequency, spectrum, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1101/407734 Free, Available for download, Freely available biotools:GADMA https://bio.tools/GADMA SCR_017680 Genetic Algorithm for Demographic Model Analysis 2026-02-15 09:22:05 3
shinyGEO
 
Resource Report
Resource Website
shinyGEO (RRID:SCR_017605) software resource, web application, service resource, production service resource, analysis service resource Web based tool to download gene expression datasets from GEO in order to perform differential expression and survival analysis for gene of interest. Produces publication ready graphics and generates R code ensuring that all analyses are reproducible. Web based application for analyzing gene expression omnibus datasets. Gene, expression, dataset, GEO, differencial, analysis, gene, graphic, omnibus, data, bio.tools uses: Shiny
is listed by: Debian
is listed by: bio.tools
has parent organization: Eastern Connecticut State University; Connecticut; United States
works with: Gene Expression Omnibus (GEO)
Google Summer of Code PMID:27503226 Free, Available for download, Freely available biotools:shinygeo https://gdancik.github.io/shinyGEO/
https://bio.tools/shinygeo
SCR_017605 2026-02-15 09:22:04 0
refgenie
 
Resource Report
Resource Website
1+ mentions
refgenie (RRID:SCR_017574) data management software, software application, service resource, software resource Software tool to organize, retrieve, and share genome analysis resources. Reference genome assembly asset manager. In addition to genome indexes, can manage any files related to reference genomes, including sequences and annotation files. Includes command line interface and server application that provides RESTful API, so it is useful for both tool development and analysis. Organize, retrive, share, genome, analysis, reference, assembly, asset, manager, sequence, annotation, file, command, line, interface, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/698704 Free, Available for download, Freely available biotools:Refgenie https://bio.tools/Refgenie SCR_017574 reference genome manager 2026-02-15 09:22:08 6
CRISPy-web
 
Resource Report
Resource Website
10+ mentions
CRISPy-web (RRID:SCR_017970) web service, data access protocol, software resource Web tool to design sgRNAs for CRISPR applications. Web tool based on CRISPy to design sgRNAs for any user-provided microbial genome. Implemented as standalone web application for Cas9 target prediction. Design, sgRNA, CRISP, microbial, genome, Cas9, target, prediction, data, guide, single, editing, bio.tools is listed by: bio.tools
is listed by: Debian
Novo Nordisk Foundation PMID:29062934 Free, Freely available biotools:crispy https://bio.tools/crispy SCR_017970 single guide RNA desing 2026-02-15 09:22:09 25
PAFScaff
 
Resource Report
Resource Website
1+ mentions
PAFScaff (RRID:SCR_017976) software application, sequence analysis software, data processing software, software resource, data analysis software Software as Pairwise mApping Format reference based Scaffold anchoring and super scaffolding tool. Dsigned for mapping genome assembly scaffolds to closely related chromosome level reference genome assembly. Pairwise, mapping, reference, scaffold, genomics, scaffolding, assembly, genome, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:PAFScaff https://github.com/slimsuite/pafscaff/blob/master/PAFScaff.md
https://slimsuite.github.io/pafscaff/
https://bio.tools/PAFScaff
SCR_017976 Pairwise mApping Format reference-based Scaffold 2026-02-15 09:21:30 4
CandiMeth
 
Resource Report
Resource Website
1+ mentions
CandiMeth (RRID:SCR_017974) CandiMeth software application, data processing software, software resource, service resource, production service resource, analysis service resource, data analysis software Software tool for visualisation and quantification of DNA methylation at candidate features. DNA, methylation, candidate feature, visualisation, quantification, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
Medical Research Council ;
ESRC/BBSRC
Free, Freely available biotools:CandiMeth http://bit.do/candimeth
https://usegalaxy.org/u/sarajayne-thursby/w/candimeth-8
https://bio.tools/CandiMeth
SCR_017974 CANDIdate feature METHylation 2026-02-15 09:22:09 2
fineSTRUCTURE
 
Resource Report
Resource Website
10+ mentions
fineSTRUCTURE (RRID:SCR_018170) software application, data processing software, data analysis software, software resource Software tool as algorithm for identifying population structure using dense sequencing data. Can perform model based Bayesian clustering on large datasets, including full resequencing data. Identifying population structure, dense sequencing data, Bayesian clustering, large dataset, data, analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:finestructure https://bio.tools/finestructure SCR_018170 FineSTRUCTURE version 2 2026-02-15 09:22:11 23
ChiCMaxima
 
Resource Report
Resource Website
1+ mentions
ChiCMaxima (RRID:SCR_018178) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling. Chromatin loop, CHi-C promoter, data, Hi-C visualization, interaction calling, data, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31118054 Free, Freely available biotools:ChiCMaxima https://bio.tools/ChiCMaxima SCR_018178 2026-02-15 09:22:11 2
SnpHub
 
Resource Report
Resource Website
1+ mentions
SnpHub (RRID:SCR_018177) web application, software resource Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data. Genomic, data, data visualization, data analysis, data retrieving, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31701415;
National Key Research and Development Program of China 2018YFD0100803;
National Key Research and Development Program of China 2016YFD0100801
Free, Available for download, Freely available biotools:SnpHub http://guoweilong.github.io/SnpHub/
https://bio.tools/SnpHub
SCR_018177 2026-02-15 09:22:11 1
SpydrPick
 
Resource Report
Resource Website
1+ mentions
SpydrPick (RRID:SCR_018176) software application, data processing software, data analysis software, software resource Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree. Direct coupling analysis, aligned categorical datasets, analysis, genome, bacteria, phylogenetic signal, correction, phylogenetic tree, data, bio.tools is listed by: Debian
is listed by: bio.tools
COIN Center of Excellence ;
Academy of Finland ;
Wellcome Trust ;
European Research Council
PMID:31361894 Free, Available for download, Freely available biotools:SpydrPick https://anaconda.org/bioconda/spydrpick
https://bio.tools/SpydrPick
SCR_018176 2026-02-15 09:22:19 2
CRISPRdirect
 
Resource Report
Resource Website
100+ mentions
CRISPRdirect (RRID:SCR_018186) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Software for designing CRISPR/Cas guide RNA with reduced off target sites. Used for rational design of CRISPR/Cas target. Web server for selecting rational CRISPR/Cas targets from input sequence. Server currently incorporates genomic sequences of human, mouse, rat, marmoset, pig, chicken, frog, zebrafish, Ciona, fruit fly, silkworm, Caenorhabditis elegans, Arabidopsis, rice, Sorghum and budding yeast. CRISP/Cas guide RNA, reduced off target site, design of CRISP/Cas target, selecting rational target, sequence, genomic sequence, RNA, bio.tools is listed by: Debian
is listed by: bio.tools
Japan Science and Technology Agency ;
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan
PMID:25414360 Free, Freely available biotools:CRISPRdirect https://bio.tools/CRISPRdirect SCR_018186 2026-02-15 09:22:11 452
Fcirc
 
Resource Report
Resource Website
1+ mentions
Fcirc (RRID:SCR_018090) Fcirc workflow software, software application, data processing software, software resource Software Python pipeline for linear and circular RNAs of known fusions exploration. Pipeline for exploring linear transcripts and circRNAs of known fusions based on RNA-Seq data. Known fusion genes are from multiple databases like COSMIC, ChimerDB, TicDB, FARE-CAFE and FusionCancer or user-added gene-pairs. Fusion gene, linear and circular RNA, fusion exploration, RNAseq data, linear transcript, circRNA, gene, data, pipeline, bio.tools uses: HISAT2
uses: SAMTOOLS
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31771469 ;
National Natural Science Foundation of China 31571363 ;
National Natural Science Foundation of China 81573023 ;
National Key Research and Development Program 2017YFC0908500
Free, Available for download, Freely available biotools:Fcirc https://bio.tools/Fcirc SCR_018090 Comprehensive Pipeline for Exploration of Fusion Linear and Circular RNAs 2026-02-15 09:21:31 2
HingeProt
 
Resource Report
Resource Website
1+ mentions
HingeProt (RRID:SCR_018136) web service, data access protocol, service resource, software resource Web server for predicting rigid protein parts and flexible hinge regions connecting them in native topology of protein chains by employing elastic network (EN) models. Automated prediction of hinges in protein structures. Predicting protein hinges, flexible hinge region, native topology, rigid protein part, elastic network model, protein structure, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:17847101 Free, Available for download, Freely available biotools:hingeprot https://bio.tools/hingeprot SCR_018136 2026-02-15 09:22:10 4
GPS-SUMO
 
Resource Report
Resource Website
1+ mentions
GPS-SUMO (RRID:SCR_018261) portal, software resource, data access protocol, web service, service resource, data or information resource Web service for prediction of SUMOylation sites and SUMO-interaction motifs in proteins by CUCKOO Workgroup. Small ubiquitin like modifier, SUMOs, sumoylation, covalently modified protein, group prediction system, site prediction, interaction motif in protein, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
National Basic Research Program ;
Guangdong Natural Science Funds for Distinguished Young Scholar ;
Zhujiang Nova Program of Guangzhou ;
International Science and Technology Cooperation Program of China
PMID:24880689 Restricted biotools:gps-sumo http://sumosp.biocuckoo.org/online.php
https://bio.tools/gps-sumo
SCR_018261 Group-based Prediction System -Small Ubiquitin-like MOdifiers, Small Ubiquitin-like MOdifiers sp, GPS-SUMO 2.0, SUMOsp, GPS Small Ubiquitin-like MOdifiers, Group-based Prediction System-SUMO 2026-02-15 09:22:12 2
VEnCode
 
Resource Report
Resource Website
1+ mentions
VEnCode (RRID:SCR_018024) VEnCode software application, data processing software, data analysis software, software resource Software tool to perform intersectional genetics-related operations to find VEnCodes using databases provided by FANTOM5 consortium, namely CAGE enhancer and transcription start site (TSS) databases. FANTOM5 consortium, data, CAGE enhancer, transcription site database, intersectional genetics, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/552984 Free, Available for download, Freely available BioTools:VEnCode, biotools:VEnCode https://bio.tools/VEnCode
https://bio.tools/VEnCode
https://bio.tools/VEnCode
SCR_018024 Versatile Entry Codes 2026-02-15 09:22:18 1
Warp
 
Resource Report
Resource Website
1+ mentions
Warp (RRID:SCR_018071) software application, data processing software, software resource, data acquisition software, data analysis software Software tool that automates all preprocessing steps of cryo-EM data acquisition and enables real-time evaluation. Corrects micrographs for global and local motion, estimates local defocus and monitors key parameters for each recorded micrograph or tomographic tilt series in real time. Software includes deep-learning-based models for accurate particle picking and image denoising. Automating preprocessing step, cryo EM data acquisition, micrograph correction, particle picking, image denoising, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/s41592-019-0580-y Free, Available for download, Freely available BioTools:Warp, biotools:Warp https://bio.tools/Warp
https://bio.tools/Warp
https://bio.tools/Warp
SCR_018071 2026-02-15 09:22:18 7
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) software application, software resource, data access protocol, web service, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-15 09:22:10 149
CLIP-Explorer
 
Resource Report
Resource Website
1+ mentions
CLIP-Explorer (RRID:SCR_018128) software application, data visualization software, data processing software, software resource, service resource, data analysis software Webserver to process, analyse and visualise CLIP-Seq data. Software tools to process and visualise RNA protein interactions. CLIP-Seq data analysis in Galaxy. Galaxy CLIP-Explorer can process large CLIP-Seq data of eCLIP, iCLIP, and with simple changes to iCLIP workflows also FLASH, and uvCLAP. CLIP-seq data, RNA protein interaction, Galaxy, data analysis, eCLIP, iCLIP, FLASH, uvCLAP, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
is related to: FLASH
Restricted SCR_018130, biotools:CLIP-Explorer https://bio.tools/CLIP-Explorer SCR_018128 2026-02-15 09:22:10 2
NanoSim
 
Resource Report
Resource Website
10+ mentions
NanoSim (RRID:SCR_018243) software application, simulation software, software resource Software tool as Nanopore sequence read simulator based on statistical characterization. Oxford Nanopore Technology sequence simulator written in Python and R. Benefits development of scalable next generation sequencing technologies for long nanopore reads, including genome assembly, mutation detection, and metagenomic analysis software. Nanopore sequence read, sequence simulator, Oxford Nanopore Technology, next generation sequencing, long nanopore read, genome assembly, mutation detection, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
NHGRI R01 HG007182;
Genome Canada ;
Genome British Columbia ;
British Columbia Cancer Foundation ;
University of British Columbia
DOI:10.1093/gigascience/gix010 Free, Available for download, Freely available biotools:trans-nanosim, biotools:nanosim https://www.bcgsc.ca/resources/software/nanosim
https://bio.tools/nanosim
https://bio.tools/Trans-NanoSim
SCR_018243 2026-02-15 09:22:12 18
PlotTwist
 
Resource Report
Resource Website
10+ mentions
PlotTwist (RRID:SCR_018331) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Web application for plotting and annotating continuous data. Open source web app for plotting and annotating time series data. Used to inspect data and generate publication quality visualizations. Available options for plotting include lineplot, small multiples and heatmap, summary statistics and inferential statistics. Plotting continuous data, annotating continuous data, data visualization, time series data, line plot, small multiples, heatmap, statistic, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31929523 Free, Freely available biotools:Plottwist, BioTools:PlotTwist https://github.com/JoachimGoedhart/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
SCR_018331 PlotTwist Shiny 2026-02-15 09:22:12 10

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