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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
DichroWeb
 
Resource Report
Resource Website
50+ mentions
DichroWeb (RRID:SCR_018125) web service, data analysis service, analysis service resource, data access protocol, software resource, production service resource, service resource Web server for analysis of protein circular dichroism spectra. Provides access to circular dichroism secondary structure calculation algorithms and reference databases. Used in analysis of protein secondary structures. Analysis, protein, circular dichroism spectra, secondary structure, reference database, algorithm, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of London; London; United Kingdom
BBSRC PMID:17896349
PMID:15215473
Restricted biotools:dichroweb https://bio.tools/dichroweb SCR_018125 2026-02-16 09:49:23 62
Human Experimental/FunctionAL MaPper: Providing Functional Maps of the Human Genome
 
Resource Report
Resource Website
Human Experimental/FunctionAL MaPper: Providing Functional Maps of the Human Genome (RRID:SCR_003506) HEFalMp service resource, data or information resource, database HEFalMp (Human Experimental/FunctionAL MaPper) is a tool developed by Curtis Huttenhower in Olga Troyanskaya's lab at Princeton University. It was created to allow interactive exploration of functional maps. Functional mapping analyzes portions of these networks related to user-specified groups of genes and biological processes and displays the results as probabilities (for individual genes), functional association p-values (for groups of genes), or graphically (as an interaction network). HEFalMp contains information from roughly 15,000 microarray conditions, over 15,000 publications on genetic and physical protein interactions, and several types of DNA and protein sequence analyses and allows the exploration of over 200 H. sapiens process-specific functional relationship networks, including a global, process-independent network capturing the most general functional relationships. Looking to download functional maps? Keep an eye on the bottom of each page of results: every functional map of any kind is generated with a Download link at the bottom right. Most functional maps are provided as tab-delimited text to simplify downstream processing; graphical interaction networks are provided as Support Vector Graphics files, which can be viewed using the Adobe Viewer, any recent version of Firefox, or the excellent open source Inkscape tool. human, map, gene, functional, pathway, disease, genomic, analysis, microarray, dna, protein, sequence has parent organization: Princeton University; New Jersey; USA New Jersey Commission on Cancer Research ;
PhRMA Foundation 2007RSGl9572;
NIGMS R01 GM071966;
NSF DBI-0546275;
NSF IIS-0513552;
NHGRI T32 HG003284;
NIGMS P50 GM071508
PMID:19246570 nif-0000-37186 SCR_003506 Human Experimental / FunctionAL MaPper, Human Experimental/FunctionAL MaPper 2026-02-16 09:46:02 0
Exonic Splicing Enhancer Finder
 
Resource Report
Resource Website
50+ mentions
Exonic Splicing Enhancer Finder (RRID:SCR_002835) production service resource, service resource, data analysis service, analysis service resource A web-based analysis service for identifying exonic splicing enhancers in eukaryotic genes. ESEfinder accept sequences in the FASTA format. A typical mammalian gene is composed of several relatively short exons that are interrupted by much longer introns. To generate correct mature mRNAs, the exons must be identified and joined together precisely and efficiently, in a process that requires the coordinated action of five small nuclear (sn)RNAs (U1, U2, U4, U5 and U6) and more than 60 polypeptides. The inaccurate recognition of exon/intron boundaries or the failure to remove an intron generates aberrant mRNAs that are either unstable or code for defective or deleterious protein isoforms. Exonic enhancers are thought to serve as binding sites for specific serine/arginine-rich (SR) proteins, a family of structurally related and highly conserved splicing factors characterized by one or two RNA-recognition motifs (RRM) and by a distinctive C-terminal domain highly enriched in RS dipeptides (the RS domain). The RRMs mediate sequence-specific binding to the RNA, and so determine substrate specificity, whereas the RS domain appears to be involved mainly in protein-protein interactions. SR proteins bound to ESEs can promote exon definition by directly recruiting the splicing machinery through their RS domain and/or by antagonizing the action of nearby silencer elements. Sponsors: ESEfinder is supported by the Cold Spring Harbor Laboratory. element, enhancer, eukaryotic, exon, exonic, gene, analysis, arginine, boundary, c-terminal, dipeptide, intron, isoform, mammalian, mrna, nuclear, polypeptide, protein, recognition, rna, serine, service, snrna, splice has parent organization: Cold Spring Harbor Laboratory Free, Freely available nif-0000-25204 SCR_002835 ESEfinder 2026-02-16 09:45:51 66
BiSearch: Primer Design and Search Tool
 
Resource Report
Resource Website
50+ mentions
BiSearch: Primer Design and Search Tool (RRID:SCR_002980) BiSearch production service resource, service resource, data analysis service, analysis service resource BiSearch is a primer-design algorithm for DNA sequences. It may be used for both bisulfite converted as well as for original not modified sequences. You can search various genomes with the designed primers to avoid non-specific PCR products by our fast ePCR method. This is especially recommended when primers are designed to amplify the highly redundant bisulfite treated sequences. It has the unique property of analyzing the primer pairs for mispriming sites on the bisulfite-treated genome and determines potential non-specific amplification products with a new search algorithm. The options of primer-design and analysis for mispriming sites can be used sequentially or separately, both on bisulfite-treated and untreated sequences. In silico and in vitro tests of the software suggest that new PCR strategies may increase the efficiency of the amplification. dna, sequence, primer, design, algorithm, analysis, priming, bisulfite, genome, amplification, in vitro, in silico, amplification, epcr, cytosines has parent organization: Hungarian Academy of Sciences; Budapest; Hungary PXE International Inc. GVOP-3.1.1-2004-05-0143/3.0;
Boolyai Janos Scholarship ;
OTKA T34131;
OTKA D42207
PMID:17022803
PMID:15653630
nif-0000-30170 SCR_002980 2026-02-16 09:45:53 50
Babelomics
 
Resource Report
Resource Website
100+ mentions
Babelomics (RRID:SCR_002969) Babelomics production service resource, service resource, data analysis service, analysis service resource An integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling. Version 4 of Babelomics integrates primary (normalization, calls, etc.) and secondary (signatures, predictors, associations, TDTs, clustering, etc.) analysis tools within an environment that allows relating genomic data and/or interpreting them by means of different functional enrichment or gene set methods. Such interpretation is made not only using functional definitions (GO, KEGG, Biocarta, etc.) but also regulatory information (from Transfac, Jaspar, etc.) and other levels of regulation such as miRNA-mediated interference, protein-protein interactions, text-mining module definitions and the possibility of producing de novo annotations through the Blast2GO system . Babelomics has been extensively re-engineered and now it includes the use of web services and Web 2.0 technology features, a new user interface with persistent sessions and a new extended database of gene identifiers. In this release GEPAS and Babelomics have integrated into a unique web application with many new features and improvements: * Data input: import and quality control for the most common microarray formats * Normalization and base calling: for the most common expression, tiling and SNP microarrays (Affymetrix and Agilent). * Transcriptomics: diverse analysis options that include well established as well as novel algorithms for normalization, gene selection, class prediction, clustering and time-series analysis. * Genotyping: stratification analysis, association, TDT. * Functional profiling: functional enrichment and gene set enrichment analysis with functional terms (GO, KEGG, Biocarta, etc.), regulatory (Transfac, Jaspar, miRNAs, etc.), text-mining, derived bioentities, protein-protein interaction analysis. * Integrative analysis: Different variables can be related to each other (e.g. gene expression to gnomic copy number) and the results subjected to functional analysis. Platform: Online tool platform, analysis, transcriptomics, proteomics, genomics, normalization, clustering, gene, mirna, protein, interaction, text mining, genotyping, bioentity, functional profiling, statistical analysis, functional annotation, regulatory motif, microarray, fatigo, biclustering, networkminer, gepas, gene expression, FASEB list is listed by: OMICtools
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: BioCarta Pathways
is related to: KEGG
is related to: TRANSFAC
is related to: JASPAR
has parent organization: CIPF Bioinformatics and Genomics Department
Spanish Ministry of Science and Innovation BIO2008-04212;
Spanish Ministry of Science and Innovation CEN-2008-1002;
Red Temtica de Investigacion Cooperativa en Cancer RD06/0020/1019;
Instituto de Salud Carlos III
PMID:20478823
PMID:18515841
PMID:16845052
PMID:14990455
PMID:15980512
PMID:17478504
Free for academic use, Account required OMICS_00748, nif-0000-30144 http://www.fatigo.org/
http://www.gepas.org/
http://babelomics3.bioinfo.cipf.es
http://www.babelomics.org SCR_002969 Babelomics 4: Gene Expression and Functional Profiling Analysis Suite, Babelomics 4 2026-02-16 09:45:53 136
STRAP
 
Resource Report
Resource Website
100+ mentions
STRAP (RRID:SCR_005675) STRAP data processing software, software application, software resource Software program that automatically annotates a protein list with information that helps in the meaningful interpretation of data from mass spectrometry and other techniques. It takes protein lists as input, in the form of plain text files, protXML files (usually from the TPP), or Dat files from MASCOT search results. From this, it generates protein annotation tables, and a variety of GO charts to aid individual and differential analysis of proteomics data. It downloads information from mainly the Uniprot and EBI QuickGO databases. STRAP requires Windows XP or higher with at least version 3.5 of the Microsoft .NET Framework installed. Platform: Windows compatible protein, gene, annotation, mass spectrometry, proteomics, visualization, browser, differential analysis, analysis, ontology or annotation browser, ontology or annotation visualization, differential analysis of proteomics data sets, windows, protein annotation, data visualization, c#, pathway, FASEB list is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: UniProt
is related to: QuickGO
has parent organization: Boston University School of Medicine; Massachusetts; USA
NHLBI contract N01 HV28178;
NCRR P41 RR10888
PMID:19839595 Open unspecified license, Acknowledgement requested OMICS_02277, nlx_149115 SCR_005675 Software Tool for Rapid Annotation of Proteins, STRAP for GO Annotation, STRAP - Software Tool for Rapid Annotation of Proteins 2026-02-16 09:46:31 120
CellProfiler Image Analysis Software
 
Resource Report
Resource Website
1000+ mentions
CellProfiler Image Analysis Software (RRID:SCR_007358) data processing software, software application, software resource, image analysis software Software tool to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically. It counts cells and also measures the size, shape, intensity and texture of every cell (and every labeled subcellular compartment) in every image. It was designed for high throughput screening but can perform automated image analysis for images from time-lapse movies and low-throughput experiments. CellProfiler has an increasing number of algorithms to identify and measure properties of neuronal cell types. high-throughput, high content imaging, software, image, cell, phenotype, measurement, subcellular, intensity, size, shape, analysis, algorithm is listed by: Debian
is related to: CellProfiler Analyst
has parent organization: Broad Institute
NIGMS R01 GM089652;
NIGMS RC2 GM092519;
NHGRI RL1 HG004671
PMID:21349861
PMID:17076895
PMID:19014601
PMID:19188593
Free, Available for download, Freely available SCR_010649, nlx_66812, nif-0000-00280 https://sources.debian.org/src/cellprofiler/ SCR_007358 Cell Profiler, CellProfiler - cell image analysis software 2026-02-16 09:46:57 3265
MarsBaR region of interest toolbox for SPM
 
Resource Report
Resource Website
1000+ mentions
MarsBaR region of interest toolbox for SPM (RRID:SCR_009605) MarsBaR data processing software, software application, software resource, software toolkit A toolbox for SPM which provides routines for region of interest analysis. Features include region of interest definition, combination of regions of interest with simple algebra, extraction of data for regions with and without SPM preprocessing (scaling, filtering), and statistical analyses of ROI data using the SPM statistics machinery. analyze, linear, matlab, magnetic resonance, nifti, os independent, regression, statistical operation, region of interest, spm, analysis is used by: BetA-Series COrrelation
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: SPM
has parent organization: SourceForge
GNU General Public License nlx_155806 http://www.nitrc.org/projects/marsbar SCR_009605 MARSeille Boite A Region dInteret, MARSeille Boite a Region dInteret 2026-02-16 09:47:27 1266
Gene Expression Profile Analysis Suite
 
Resource Report
Resource Website
10+ mentions
Gene Expression Profile Analysis Suite (RRID:SCR_008341) data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. An integrated packages of tools for microarray data analysis. GEPAS provides a web-based interface that offers diverse analysis options from the early step of preprocessing (normalization of Affymetrix and two-color microarray experiments and other preprocessing options), to the final step of the functional profiling of the experiment (using Gene Ontology, pathways, PubMed abstracts etc.), which include different possibilities for clustering, gene selection, class prediction and array-comparative genomic hybridization management. expression, gene, analysis, genomic, microarray, microarray platform, prediction, data set is listed by: 3DVC
has parent organization: Principe Felipe Research Centre; Valencia; Spain
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25201 SCR_008341 Gepas 2026-02-16 09:47:10 20
CURRY
 
Resource Report
Resource Website
100+ mentions
CURRY (RRID:SCR_009546) CURRY data processing software, software application, software resource Processing software for multimodal neuroimaging centered on combining functional data such as EEG and MEG with imaging data from MRI and CT to optimize source reconstruction. They are now combining Curry's strength with the acquisition and signal processing features of the SCAN software for a comprehensive EEG acquisition, data analysis, source localization and source imaging package. multimodal, atlas, application, connectivity, analysis, computed, tomography, database, eeg, meg, electrocorticography, modeling, finite, element, format, conversion, forward, inverse, image, reconstruction, meg, mesh, generation, model, magnetic resonance, pet, spect, segmentation, simulation, spatial, transformation, volumetric, neuroimaging, FASEB list is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial license nlx_155726 http://www.nitrc.org/projects/curry_7 SCR_009546 CURRY Scan 7 Neuroimaging Suite, CURRY 8, CURRY 7, CURRY Neuroimaging Suite 2026-02-16 09:47:26 160
Template Based Rotation
 
Resource Report
Resource Website
1+ mentions
Template Based Rotation (RRID:SCR_012157) TBR data processing software, software application, software resource, image analysis software A tool for functional connectivity analysis of fcMRI data that maps functional data from individual sessions onto a priori spatial components from group level parcellations. functional connectivity, analysis, fmri, fcmri, parcellation, map, template, resting state, matlab Aging NIA P01AG036694 DOI:10.1016/j.neuroimage.2014.08.022 GNU General Public License v3 rid_000095 http://nmr.mgh.harvard.edu/harvardagingbrain/People/AaronSchultz/Aarons_Scripts.html SCR_012157 Template Based Rotation (TBR) 2026-02-16 09:48:06 1
Open Babel
 
Resource Report
Resource Website
50+ mentions
Open Babel (RRID:SCR_014920) data processing software, software application, software resource, data analytics software Software toolbox that is used to convert, analyze, or store data from molecular modeling, chemistry, biochemistry and other related areas. This software is used to read, write, and convert into over 110 chemical file formats. toolbox, conversion, analysis, molecular model, chemistry, biochemistry, chemical file, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:open_babel https://bio.tools/open_babel SCR_014920 2026-02-16 09:48:39 81
Center for Computational Biology at JHU
 
Resource Report
Resource Website
1+ mentions
Center for Computational Biology at JHU (RRID:SCR_016680) CCB at JHU data or information resource, organization portal, portal Center for Computational Biology as a joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences. Multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis. center, computational, biology, genomics, genetics, DNA, RNA, sequence, technology, analysis has parent organization: Johns Hopkins University; Maryland; USA
is parent organization of: Centrifuge Classifier
SCR_016680 CCB at Johns Hopkins University, CCB at JHU, Center for Computational Biology at JHU, Center for Computational Biology at Johns Hopkins University 2026-02-16 09:49:05 1
ReproNim: A Center for Reproducible Neuroimaging Computation
 
Resource Report
Resource Website
10+ mentions
ReproNim: A Center for Reproducible Neuroimaging Computation (RRID:SCR_016001) ReproNim data or information resource, organization portal, portal Center to help neuroimaging researchers to find and share data in FAIR fashion, to describe their data and analysis workflows in replicable fashion, to manage their computational resource options so that outcomes of neuroimaging research are more reproducible. Neuroimaging, share, data, FAIR, analysis, manage, reproducible is related to: ABCD-ReproNim Course
is related to: SVNTest
is parent organization of: ReproIn: The ReproNim image input management system (featuring DataLad)
NIBIB P41 EB019936 Restricted SCR_016005 http://repronim.org SCR_016001 2026-02-16 09:48:55 12
Oufti
 
Resource Report
Resource Website
10+ mentions
Oufti (RRID:SCR_016244) data processing software, software application, software resource, image analysis software Software designed for analysis of microscopy data. It performs sub-pixel precision detection, quantification of cells and fluorescence signals, as well as other image analysis functions. microscopy, data, imaging, image, analysis, pixel, fluorescent, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM065835 PMID:26538279 biotools:oufti https://bio.tools/oufti SCR_016244 outfi 2026-02-16 09:49:00 13
SegAN
 
Resource Report
Resource Website
1+ mentions
SegAN (RRID:SCR_016215) data processing software, software application, software resource, image analysis software Image analysis software for medical image segmentation. The software is fueled by an end-to-end adversarial neural network that generates segmentation label maps. neural, network, segmentation, pixel, spatial, image, medical, analysis, labelling, loss function, segmentor NIH ;
NLM ;
LHNCBC HHSN276201500692P
Free, Available for download SCR_016215 Semantic Segmentation with Adversarial Learning (SegAN), Semantic Segmentation with Adversarial Learning, SegAN: Semantic Segmentation with Adversarial Learning 2026-02-16 09:48:59 4
cryoSPARC
 
Resource Report
Resource Website
1000+ mentions
cryoSPARC (RRID:SCR_016501) data processing software, software application, software resource, image analysis software Software integrated platform used for obtaining 3D structural information from single particle cryo-EM data. Enables automated, high quality and high-throughput structure discovery of proteins, viruses and molecular complexes for research and drug discovery. Structura Biotechnology Inc., data, processing, analysis, image, single, particle, cryo-EM, structure, discovery, automated, protein, virus, molecular, complex is related to: University of Toronto; Ontario; Canada PMID:28165473 Available free of charge for academic users with a valid institutional email address, Trail available SCR_016501 2026-02-16 09:49:02 2480
Whole Tale
 
Resource Report
Resource Website
1+ mentions
Whole Tale (RRID:SCR_017537) data or information resource, project portal, portal Platform for reproducible research. Code base for publishing data. For merging science and cyberinfrastructure pathways. Data Infrastructure Building Block (DIBBS) initiative to build scalable, open source, web-based, multi-user platform for reproducible research enabling creation, publication, and execution of tales – executable research objects that capture data, code, and complete software environment used to produce research findings. To enable researchers to define and create computational environment to manage complete conduct of computational experiments and expose them for analysis and reproducibility. Reproducible, data, merging, science, cyberinfrastructure, pathway, tale, capture, code, finding, analysis NSF 1541450 DOI:10.1016/j.future.2017.12.029 Free, Freely available https://github.com/whole-tale/wt-design-docs//blob/stable/README.rst SCR_017537 2026-02-16 09:49:15 1
BZ-H3A analyzer software
 
Resource Report
Resource Website
10+ mentions
BZ-H3A analyzer software (RRID:SCR_017375) data processing software, software application, software resource, image analysis software Software tool as analysis application BZ-H3A by Keyence, Osaka, Japan for fluorescence microscope BZ-X series. Analysis, Keyence, Japan, fluorescence, microscope, BZ-X SCR_017375 2026-02-16 09:49:13 10
Sniffles
 
Resource Report
Resource Website
50+ mentions
Sniffles (RRID:SCR_017619) data processing software, software application, software resource Software tool as structural variation caller using third generation sequencing (PacBio or Oxford Nanopore). It detects all types of SVs (10bp+) using evidence from split-read alignments, high-mismatch regions, and coverage analysis. Used to avoid single molecule long read sequencing high error rates. Structural, variation, caller, third, generation, sequencing, SV, split, read, alignment, mismatch, region, analysis, error, bio.tools is listed by: bio.tools
is listed by: Debian
NHGRI R01 HG006677;
NHGRI UM1 HG008898
PMID:29713083 Free, Available for download, Freely available biotools:sniffles https://bio.tools/sniffles SCR_017619 2026-02-16 09:49:16 59

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