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https://centers.louisville.edu/brown-cancer-center/core-facilities/medicinal-chemistry

Core Facility provides essential medicinal and organic chemistry support for drug discovery. The core specializes in the lead optimization of an initial lead compound to improve biological activity and drug-like properties, and to elucidate structure activity relationships. Other services include the design and synthesis of fluorescent and isotopic probes, compound scale up (1 – 5 grams), and custom synthesis.

Proper citation: University of Louisville Medicinal Chemistry Core Facility (RRID:SCR_026397) Copy   

•   Source: SciCrunch Registry

https://prisme.institutducerveau.org/

Core facility dedicated to the study of human cognition and normal and pathological human behavior either via computer tests or in simulations, including using virtual reality.

Proper citation: Paris Brain Institute PRISME Core Facility (RRID:SCR_026394) Copy   

•   Source: SciCrunch Registry

https://ephys.institutducerveau.org/

Core develops solutions to meet your needs in electrophysiology data. Provides electrophysiology services to the neuroscience scientific community. Core has standard recording equipment such as patch clamp techniques or electroencephalographic (EEG) recordings.

Proper citation: Paris Brain Institute Electrophysiology Core Facility (RRID:SCR_026412) Copy   

•   Source: SciCrunch Registry

https://touchstonelabs.org/metabolic-phenotyping-core

Academic core facility provides analytical and phenotypical measures to the scientific community. Provides services related to metabolic disorders (diabetes and obesity), cancer, aging neurological disorders, etc. Provides letters of support for grant proposals and research applications.

Proper citation: University of Texas Southwestern Medical Center Dallas Metabolic Phenotyping Core Facility (RRID:SCR_026404) Copy   

•   Source: SciCrunch Registry

https://okinbre.ouhsc.edu/Core-Facilities#Bioinformatics

Core provides data science analysis support, training and promotion of data science education for undergraduate and high school students in the state of Oklahoma. Services include 1) Global analysis of gene expression data using custom spotted microarrays and commercial Affymetrix and Combimatrix arrays to examine gene expression patterns in mice, adenovirus-infected cells, and a variety of bacterial systems. 2) Genome annotation and comparative genomics analysis, including studies on several bacterial and viral pathogens important for human and agricultural disease. Informatics support for genome sequencing projects, annotation support, and post-sequence studies. Bioinformatics educational include analysis of laboratory data for DNA barcoding, instructional materials for protein structure analyses and phylogenetic analyses, and microbial and viral genome sequence annotation and analysis, career counseling to undergraduate students, both individually and in large groups, supervision of undergraduate summer interns and high school interns to enhance interest in pursuing bioinformatics as a career path, providing instructional materials for high school teachers interested in incorporating bioinformatics into their lesson plans.

Proper citation: University of Oklahoma Health Sciences Center OK INBRE Data Science Core Facility (RRID:SCR_026422) Copy   

•   Source: SciCrunch Registry

https://nuance.northwestern.edu/facilities/spid/index.html

SPID provides imaging instrumentation and support facilities for atomic to molecular imaging. Supports broad range of nanoscale science and technology characterization needs at nanoscale by providing resources coupled with expert staff. Research at SPID encompasses physical and chemical sciences, engineering and life sciences, and has a strong inter-disciplinary emphasis.

Proper citation: Northwestern University NUANCE SPID Core Facility (RRID:SCR_026380) Copy   

•   Source: SciCrunch Registry

https://my.ilabsolutions.com/service_center/show_external/3232/

Core provides access to technology, experience, and expertise in molecular biology methods.Offers expertise in bioinformatics needed to acquire, analyze, and visualize data generated from high throughput technologies used in genomics research. Services include Illumina sequencing,Bioinformatics and statistical analysis,PacBio sequencing,Oxford Nanpore sequencing,High-throughput DNA and RNA library preparation,Double-barcoded amplicon sequencing. GBRC also participates in many of the bioinformatic analyses from the projects including De novo genome and transcriptome assembly, RNAseq differential expression analysis, SNP calling, RAD sequence analysis, Dual-barcoded amplicon community analysis, Phylogenetic analysis, CRISPR transformant profiling,Speed congenics, Novel agriculture virus detection and assembly.

Proper citation: University of Idaho IIDS Genomics and Bioinformatics Resource Core Facility (RRID:SCR_026416) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/immune-monitoring/

Core provides services in Assay Development, Assays Experimental Design, Immune Monitoring, Cytokine Assays, ELISA, multiplex Flow based and Luminex based Bead Arrays, Project Based Flow Cytometry and Data Analysis.

Proper citation: Augusta University Georgia Cancer Center Immune Monitoring Shared Resource Core Facility (RRID:SCR_026590) Copy   

•   Source: SciCrunch Registry

https://centers.louisville.edu/brown-cancer-center/core-facilities/nmr

Core Facility houses 600 MHz Bruker Avance Neo NMR spectrometer available for both collaborative and fee-for-service use. The facility is equipped with a 14.1 T Bruker system and a nitrogen-cooled Prodigy probe, enabling a range of 3D experiments on isotopically labeled biomolecules with enhanced sensitivity for challenging samples. Services include biomolecular structure determination, characterization of biomolecular motions, and stable isotope-resolved metabolomics for studying metabolic pathways.

Proper citation: University of Louisville Nuclear Magnetic Resonance Spectroscopy Core Facility (RRID:SCR_026517) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/imagingcore

Core is multi-user facility located on the 4th floor in the Translational Research Building (TRB) at A4-110. It houses microscopes and image data analysis computers to provide imaging for wide range of samples, including cell structures in tissue sections, and subcellular structures and 3D morphologies of single cells. A full-time technician provides training, consultation, and guidance to researchers, from sample preparation to data analysis.

Proper citation: University of British Columbia BCCHR Imaging Core Facility (RRID:SCR_026573) Copy   

•   Source: SciCrunch Registry

https://tetramer.yerkes.emory.edu

Core produces and distributes of MHC/peptide tetramers and related reagents. Production and distribution to the research community of major histocompatibility complex (MHC) tetramers and related reagents for detection of T cell responses to viruses, bacteria, parasites, tumors, auto-antigens, and other model antigens. Reagents are provided to qualified investigators at no cost, except for shipping and handling fees and in cases where investigator is asked to provide the TCF with peptide or other appropriate ligands.

Proper citation: Emory University NIH Tetramer Core Facility (RRID:SCR_026557) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/proteomics-metabolomics/

Core provides advanced mass-spectrometric instrumentation and for both proteomics and metabolomic experiments. Performs qualitative and quantitative analysis of proteins and post-translationally modified peptides and both targeted and untargeted LC/GC-MS based metabolomics.

Proper citation: Cleveland Clinic Lerner Research Institute Proteomics and Metabolomics Core Facility (RRID:SCR_026563) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/flowcore

Facility provides equipment for flow cytometric analysis and full-service cell sorting, as well as flow cytometry training and education for new users.

Proper citation: University of British Columbia BCCHR Flow Cytometry Core Facility (RRID:SCR_026601) Copy   

•   Source: SciCrunch Registry

https://www.mayo.edu/research/core-facilities/overview

Core is equipped with instrumentation in mass spectrometry, sample preparation, and automation technology. Bruker timsTOF Ultra 2 ultra-high speed and sensitivity mass spectrometer for single cell and other low input proteomics methods. It comes equipped with the Bruker nanoElute 2 UHPLC and the alternative EvosepOne HPLC for high throughput applications. Sample preparation can be automated using the Opentrons Flex liquid handling robot.

Proper citation: Mayo Clinic Florida Multi-Omics Mass Spectrometry Core Facility (RRID:SCR_026559) Copy   

•   Source: SciCrunch Registry

https://www.txgen.tamu.edu/

Core provides services including Sequencing, Library preparation, Bioinformatics Analysis and Processing. Experienced staff provide expertise to users.

Proper citation: Texas A and M University System Genomics and Bioinformatics Service Core Facility (RRID:SCR_026632) Copy   

•   Source: SciCrunch Registry

https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/vector-core

Vector Core produces gene transfer vectors that facilitate transfer of specific genes into either normal or aberrant cells. Provides intellectual and technical advice to researchers regarding the optimal use of these systems.

Proper citation: University of Michigan Medical School BRCF Vector Core Facility (RRID:SCR_026696) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/research/research-resources/core-facilities/advanced-microscopy-core.html

Core provides microscopy services to departments at MD Anderson in high resolution and multispectral fluorescence microscopy for users from divisions including Basic Research, Cancer Medicine, Diagnostic Imaging, Surgery, Internal Medicine Pediatrics and Radiation Oncology, among others. Offers microscopy resources and expertise in fluorescence imaging to spatially and dynamically assess cells, tissues and their requisite contents across scales.

Proper citation: University of Texas MD Anderson Cancer Center Advanced Microscopy Core Facility (RRID:SCR_026611) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/metabolomics

Analytical Core for Metabolomics and Nutrition (ACMaN) is located on the first floor of the Varity Building. ACMaN allows researchers to analyze and track biological compounds, such as nutrients to track how these small molecules change during course of disease or treatment to better understand the disease itself and to develop new diagnostic tools and therapies. ACMaN plays role in research on metabolic diseases, hormones, and the effects of nutrition on childhood development.

Proper citation: University of British Columbia BCCHR Analytical Core for Metabolomics and Nutrition Core Facility (RRID:SCR_026603) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/microbial-sequencing/

Core provides services, from DNA and RNA extraction from diverse sample types such as tissue, stool, and bacterial isolates to next-generation sequencing, including whole-genome sequencing, total RNA-seq, metatranscriptomics, and dual RNA-seq, along with expert bioinformatics support. Core expertise spans 16S rRNA amplicon sequencing, shotgun metagenomics, metatranscriptomics, meta-omics analysis of dual RNA-seq, and single-cell RNA-seq data. Core also assists with experimental design and power calculations to ensure statistically robust results, offering consultation at every stage, from experimental design to data interpretation and troubleshooting.

Proper citation: Cleveland Clinic Lerner Research Institute Microbial Sequencing and Analytics Core Facility (RRID:SCR_026609) Copy   

•   Source: SciCrunch Registry

https://obc.bio.uci.edu/

Shared resource facility to provide researchers access to resources, including state of the art instrumentation and technical support, to conduct biomedical research. Provides access to light microscopes (confocal, mesoscale lightsheet, and Super Resolution), as well as software for 3D and 4D analysis.

Proper citation: University of California at Irvine Optical Biology Core Facility (RRID:SCR_026614) Copy   

•   Source: SciCrunch Registry