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http://www.utsouthwestern.edu/research/core-facilities/obrien-kidney/core-services/animal-core.html
Core that generates and distributes several kidney-specific Cre recombinase and tetracycline-inducible activator and repressor lines to be crossed to floxed or tet responder lines provided by co-investigators.
Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Animal Models Core (RRID:SCR_015292) Copy
http://www.kidneycenter.pitt.edu/cores/biostatistics.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented on Feb 16, 2022. Core that offers biostatistical analysis to users of the Pittsburgh Center for Kidney Research. Available to the Pittsburgh Center for Kidney Research community.
Proper citation: Pittsburgh Center for Kidney Research Biostatistical Analysis Services (RRID:SCR_015290) Copy
Core that provides measurement of serum and or urine Creatinine by Capillary Electrophoresis, measurement of serum and urine citrate by capillary electrophoresis, Microanalysis of serum and urine electrolytes by: Flame photometry, Atomic absorption or Ion-Selective Electrode, and Klotho IP-IB Assay.
Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Physiology Core (RRID:SCR_015266) Copy
http://www.dukekidneycenter.org/cores/animal-models-core
Core facility that provides access to a range of experimental models of kidney, heart and vascular diseases. It also provides comprehensive phenotyping services for kidney functions, blood pressure and other cardiovascular functions.
Proper citation: Duke O'Brien Center for Kidney Research Animal Models Core (RRID:SCR_015267) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/center-of-excellence/cores
Core aims include to empower the Nephrology Center of Excellence investigators by providing access to integrated state of the art gene expression technologies with which to apply genomics methods to accelerate molecular nephrology research, educate, assist, and improve the use of global genomics approaches, infrastructure and specialized tools for the enhancement of research productivity and discovery by the Nephrology Center of Excellence investigators, and develop and disseminate specialized data sets and the use of advanced analytic techniques and/or protocols to facilitate translation of research data to accelerate basic and applied research and its translation to improved clinical care.
Proper citation: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Gene Expression Core (RRID:SCR_015301) Copy
https://digestivediseasescenters.org/content/ddrc-uab-genetically-defined-microbe-core
Core composed of the Viral Unit, which provides labeled andn unlabeled viral components, and Bacterial Unit, which provides bacteria and bacterial proteins for research. The retroviral unit focues on the viral components of the retrovirus HIV-1.
Proper citation: Mucosal HIV and Immunobiology Center Genetically-Defined Microbe Core (RRID:SCR_015262) Copy
Core facility which generates and provides gnotobiotic and genetically engineered mice to research projects. It also provides specialized breeding, marker-assisted genotyping, and histopathologic evaluation services for studies using these mice.
Proper citation: Mucosal HIV and Immunobiology Center Gnotobiotic and Genetically-Engineered Mouse Core (RRID:SCR_015263) Copy
http://www.mayo.edu/research/centers-programs/molecular-genetics-proteomics-core/overview
Core services include mutation screening of cell lines derived from ADPKD patients, mutation screening of large, typical ADPKD populations, genetic screening of atypical PKD families, cystic Kidney and Liver Disease Biobank (CKLBB) from ADPKD patients, and urine collection and fractionation.
Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core (RRID:SCR_015308) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/center-of-excellence/cores
Core that provides quantitation and identification of protein changes by 2D gel-based methods and isotope tagging and nanoLC-MS/MS, identification of protein biomarkers detected from biofluids in the Biomarker Core, and provision of dedicated and expert Biostatistical and Bioinformatic support for data analysis.
Proper citation: Cincinnati Children's Hospital Pediatric Center of Excellence (RRID:SCR_015306) Copy
http://medicine.iupui.edu/neph/obrien/administration
Core facility which manages and directs the activities of the O'Brien Center, facilitates interactions and collaborations among the research base, ensures quality control of the core services and promotes scientific development and enrichment on the IU SOM campus.
Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Administration Core (RRID:SCR_015277) Copy
http://www.uab.edu/medicine/hrfdcc/cores/b
Core whose goals include Generation of New Animal and Cell Models of HRFDs, to establish In Vivo Biosensors to Study Signaling Pathways Involved in HRFD Ciliopathies, and to generate and distribute HRFD Related Biologicals to the Center?s Investigator Base.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Engineered Models Resource (RRID:SCR_015310) Copy
https://www.uab.edu/medicine/obriencenter/cores/pre-clinical-studies-of-aki
Core that provides services such as expertise in development and training in the use of rodent models of AKI, specifically in the setting of ischemia/reperfusion (I/R) injury, sepsis and renal transplantation, gamma-ray imaging (gamma camera, microSPECT/CT, microPET/CT), metabolic assessments of kidney O2 consumption, and technical expertise in isolation of primary renal and vascular cell in culture.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Pre-Clinical Studies of AKI (RRID:SCR_015278) Copy
http://medicine.iupui.edu/NEPH/OBRIEN/EDUCATIONCORE
Core faciltiy which provides instructional workshops, a visiting speakers program, and a web resource for the dissemination of methods, educational materials and software relating to imaging technologies.
Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Education Core (RRID:SCR_015275) Copy
https://www.uab.edu/medicine/obriencenter/center-overview/administration
Core facility which coordinates the various activities of the center. Its various duties include facilitating interactions and collaboration among the researchers of the center, promoting scientific development through education and Pilot funding, organizing and supporting seminars, journal clubs and symposia, and maintaining communication with members.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Administrative Core (RRID:SCR_015279) Copy
http://www.mayo.edu/research/centers-programs/model-systems-core/overview
Core that makes available PKD model systems and technologies to PKD researchers at Mayo and at other institutions. Its services include C. elegans PKD-targeted services, Zebrafish PKD-targeted services, and Rodent PKD-targeted services.
Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core (RRID:SCR_015312) Copy
http://medicine.iupui.edu/neph/obrien/intravital
Core facility which primarily provides service, animal models, consultation training and intravital optical microscopy customized to kidney and urologic research. It also develops and characterizes novel biosensor probes and in vivo delivery methods for these probes, as well as intravital multiphoton microscopy technologies.
Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Intravital Microscopy Core (RRID:SCR_015273) Copy
http://www.massgeneral.org/csibd/cores/immunology.aspx
Core whose focus is on modern approaches to the study of the human immune system and their application to the study of IBD and related disorders. Its services include routine immunology tools, specialized immunology services, and education and training services.
Proper citation: Center for the Study of Inflammatory Bowel Disease Immunology Core (RRID:SCR_015239) Copy
https://ddrcc.wustl.edu/scientific-cores/biobank-core/
Core facility that collects and provides specimens and longitudinal clinical data from patients with digestive diseases. Specimens collected and processed by the core currently include blood, surgical resections, endoscopic biopsies, and stool. Clinical information is stored in a database and linked to specimens and data obtained from these specimens.
Proper citation: Washington University Digestive Diseases Research Core Center Biobank Core (RRID:SCR_015256) Copy
https://ddrcc.wustl.edu/scientific-cores/administrative-resource-access-core/
Core facility which provides DDRCC members facilitated access to technology and assistance for genetic profiling of clinical and experimental samples.
Proper citation: Washington University Digestive Diseases Research Core Center Administrative and Resource Access Core (RRID:SCR_015253) Copy
https://ddrcc.wustl.edu/scientific-cores/advanced-imaging-tissue-analysis-core/
Core facility which provides comprehensive histologic and immunohistochemical support, advanced microscopic imaging and image analysis services to digestive disease researchers. The Tissue Analysis Component performs animal and human tissue embedding, sectioning, routine and special staining, and immunohistochemical analyses, and provides training in all services while the Advanced Image Analysis Component provides access to and training in routine light, fluorescent and inverted fluorescent microscopy and quantitative image analysis.
Proper citation: Washington University Digestive Diseases Research Core Center Advanced Imaging and Tissue Analysis Core (RRID:SCR_015254) Copy
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