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https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models

Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�

Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy   

•   Source: SciCrunch Registry

https://www.cshl.edu/research/cancer/flow-cytometry/

Resource provides equipment, training, and operating assistance for cell sorting and analysis. Facility staff oversees equipment maintenance, trains new users, and assists with assay development and operation of equipment.

Proper citation: Cold Spring Harbor Laboratory Flow Cytometry Shared Resource Core Facility (RRID:SCR_022164) Copy   

•   Source: SciCrunch Registry

https://www.abdn.ac.uk/ims/facilities/cytometry/

Provides services and expertise in flow cytometry to government agencies, industry, educational and private individuals.

Proper citation: University of Aberdeen Iain Fraser Cytometry Centre Core Facility (RRID:SCR_022315) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/flow-image-cytometry

Provides advanced flow cytometric and morphology services at cellular and subcellular levels of resolution.Services include investigator access to equipment, education and consultation, comprehensive sample processing, data acquisition and data analysis, luminex cytokine, chemokine and growth factor quantification, and core flow cytometry services for investigator and biotech sponsored clinical trials.

Proper citation: Roswell Park Cancer Institute Flow and Image Cytometry Shared Resource Core Facility (RRID:SCR_022313) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/electronmicroscopyresourcelab/

Training and service facility dedicated to providing both conventional transmission electron microscopy of cells and tissues and state of the art cryo-electron microscopy and cryo-electron tomography for structural investigation of macromolecules and cells.

Proper citation: University of Pennsylvania Perelman School of Medicine Electron Microscopy Resource Lab Core Facility (RRID:SCR_022375) Copy   

•   Source: SciCrunch Registry

https://bioinfo.med.upenn.edu/

Core provides bioinformatics services that include data analysis and consultation and building of efficient pipelines that handle various biomedical data including Next-Generation Sequencing (NGS) data.

Proper citation: University of Pennsylvania Perelman School of Medicine Bioinformatics Core Facility (RRID:SCR_022374) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cdbmicroscopycore/

Core provides personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to assistance with image data analysis. Facility houses confocal microscopes, Bruker Vutara 352 super resolution system, Zeiss Z.1 Lightsheet system, three widefield light microscopes, and several computers dedicated to image processing and analysis. Offers scanning electron microscope sample preparation and imaging.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Developmental Biology Microscopy Core Facility (RRID:SCR_022373) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cfar/virus-reservoirs.html

Facility provides comprehensive viral and molecular support in area of basic, translational and clinical HIV research, consultation, training, and mentoring.Is available to develop customized viral and molecular support services as needed. Offers deep sequencing support and single genome amplification services.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for AIDS Research Virus and Reservoirs Core Facility (RRID:SCR_022403) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/chps/

CHPS is comprised of several Clinical Research Cores designed to facilitate research process. Provides resources, environment, operations, and training to support and promote high quality clinical and translational research by qualified investigators.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Human Phenomic Science (CHPS) (RRID:SCR_022402) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/cear.html

Core aims to facilitate and build capacity for community based research and community engagement, while enhancing translation of research and technological developments to key public health and community stakeholders. Offers consultation on community engagement, training in participatory research methods, and assistance with development, implementation, and evaluation of community translation activities. Core is part of the Penn Institute for Translational Medicine and Therapeutics (ITMAT).

Proper citation: University of Pennsylvania Perelman School of Medicine Community Engagement and Research Core Facility (RRID:SCR_022408) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/tcmf/

Facility provides centralized service to efficiently produce genetically altered mice for basic research.� They include transgenic, chimeric and genome edited mice carrying transgenes or gene knockout and Knockin of specific interest.�Core also provides embryo and sperm cryopreservation as well as in vitro fertilization and re-derivation of live and cryopreserved lines, along with long-term storage of cryopreserved samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Transgenic and Chimeric Mouse Core Facility (RRID:SCR_022388) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/OCRCBioTrust/

Provides specimens including gynecologic cancer specimens such as fresh and frozen tissues, plasma, serum, peripheral blood mononuclear cells, blood, formalin fixed paraffin embedded (FFPE) samples, and Tissue Microarrays (TMAs). All samples collected have clinical annotation including demographic patient profiles, pathological and clinical notations, treatment history, and detail disease information, etc. We are building and maintaining centralized research database according to HIPPA specifications and Penn IRB standards.

Proper citation: University of Pennsylvania Perelman School of Medicine Ovarian Cancer Research Center Tumor BioTrust Collection Core Facility (RRID:SCR_022387) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/NBTC.html

Core provides equipment and services to investigate behavior phenotypes of models related to neurological and other disorders. Core is utilized by scientists across disciplines that are interested in behavioral consequences of unique physiological disruptions (e.g., metabolic, drugs etc.). Provides assessment of many domains of behavior including sensory, motor, social, communication, affect related behaviors and learning and memory. NTC was established in 2012 through generous startup funds from the Penn School of Medicine, the Institute for Translational Medicine and Therapeutics (ITMAT), Center for Sleep and Circadian Neurobiology (CSCN) and Penn Medicine Neuroscience Center (PMNC).

Proper citation: University of Pennsylvania Perelman School of Medicine Neurobehavior Testing Core Facility (RRID:SCR_022386) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/saif-small-animal-imaging-facility

Core provides comprehensive suite of imaging modalities including magnetic resonance imaging (MRI), spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US). In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of SAIF are devoted to radiochemistry and image analysis.

Proper citation: University of Pennsylvania Perelman School of Medicine Small Animal Imaging Core Facility (RRID:SCR_022385) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/genomic-analysis-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 8th,2024. Facility offers sequencing services on three platforms, gold standard Sanger sequencing on ABI capillary sequencers, next generation sequencing (NGS) on Ion Torrent PGM and S5 and, Illumina MiSeq along with experimental design and data analysis.NGS service includes library preparation for multiple applications including targeted sequencing, RNA-Seq and Exome-Seq. Capillary sequencers also enable microsatellite genotyping and fragment analysis for VNTR, SNaPshot and Human Cell Line Authentication. Molecular biological services include PCR, cloning, subcloning, mutagenesis, construct preparation and, plasmid DNA preps at different scales.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis DNA Sequencing Core Facility (RRID:SCR_022383) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/fmch/mixed-methods-research-lab

Fosters the use of qualitative and mixed methods research methodologies with focus on integrating key stakeholder perspectives and goals into research designs. Collaborates with investigators to address timely, pressing questions across diverse disciplines and works with investigators to provide conceptual as well as technical support for broad research programs, including clinical, community based, and implementation science research questions.

Proper citation: University of Pennsylvania Perelman School of Medicine Mixed Methods Research Lab Core Facility (RRID:SCR_022418) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-microbial-culture-and-metabolomics-core

Provides equipment for aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well as targeted metabolomic services of amino, bile, and short chain fatty acids. Offers training and usage for culture equipment; consultation regarding experimental design, and; anaerobic culture services. Examples of culture studies include isolation of microbial taxa from mammalian samples; interrogation of the physiology of microbial strains under different conditions (e.g., anaerobic/microaerobic/aerobic, differing nutrient limitations) using isolated strains or strains obtained from culture collections (another service offered by the core); co-culturing of defined microbial consortia to investigate microbe-microbe interactions, and; preparation of microbial products (live bacteria, heat-killed bacteria, bacterial supernatants) from single or defined-mixed microbial cultures for use in mammalian cell culture and/or animal model systems.

Proper citation: University of Pennsylvania Perelman School of Medicine Microbial Culture and Metabolomics Core Facility (RRID:SCR_022417) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/jf/bsbcore/index.html

Provides unique equipment and expertise to facilitate modern biophysical characterization and structural analysis of proteins and other biomolecules., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Johnson Foundation Biophysical and Structural Biology Core Facility (RRID:SCR_022414) Copy   

•   Source: SciCrunch Registry