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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Genomics core facility with goal to use instrumentation and innovative technical expertise in order to provide investigators with genomic data from comprehensive range of genomic services in timely manner. Services include Next-Generation Sequencing, Sanger Sequencing Single Cell Sequencing, Microarray Services, Fluorescent Fragment Length Analysis, nanoString nCounter Analysis, Bionano Optical Genome Mapping, Spatial Transcriptomics, Nanopore Sequencing.
Proper citation: University of Texas MD Anderson Advanced Technology Genomics Core Facility (RRID:SCR_026261) Copy
https://www.cancer.columbia.edu/research/shared-resources/confocal-and-specialized-microscopy
Advanced microscope systems for multidimensional optical imaging of living and fixed cells and tissues. Microscopy technologies include confocal, super-resolution (Airyscan and SMLM), TIRF, and wide-field microscopy as well as plate reading and laser capture microdissection. Analysis workstation and software are available, with custom pipeline development for processing, analysis, and visualization.
Proper citation: Columbia University Confocal and Specialized Microscopy Shared Resource Core Facility (RRID:SCR_026353) Copy
https://www.research.uky.edu/mass-spectrometry-and-proteomics-core
Mass spectrometry core lab performing proteomics, small molecule, and lipidomic analyses. Provides access to advanced analytical equipment for quantitation and structural analysis. Offers assistance in sample preparation, method development, acquisition, and data analysis.
Proper citation: University of Kentucky Research Mass Spectrometry and Proteomics Core Facility (RRID:SCR_026359) Copy
Facility dedicated to study of degraded and low DNA yield samples, such as environmental DNA, historical DNA, or ancient DNA. Offers positive pressure lab spaces that follow strict decontamination procedures to prevent human, bacterial, and fungal contamination. It is physically isolated from tissue samples or polymerase chain reaction (PCR) products to avoid contamination from samples with higher DNA concentration and quality. The space has dedicated equipment necessary for DNA extraction and PCR-free sample preparation.
Proper citation: Field Museum of Natural History Biomolecular Clean Laboratory Core Facility (RRID:SCR_026364) Copy
https://www.nuance.northwestern.edu/facilities/keck-ii/index.html
Core facilitates research, collaboration, education and outreach in all science from soft biological matter to hard physical matter, specializing in surface analysis and nano-scale characterization. Instruments include Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS), X-ray Photoelectron Spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FT-IR), Confocal Raman System, High Resolution Stylus Profilometer, 3D Optical Microscope, Spectroscopic Ellipsometer, and Zetasizer.Staff provides hand-on training, collaboration and assistance.
Proper citation: Northwestern University Keck Interdisciplinary Surface Science Core Facility (RRID:SCR_026360) Copy
https://nextgen.mgh.harvard.edu/Pricing.html
Core offers sequencing, upstream library construction (bulk RNA/DNA, single-cell), and post-sequencing analysis. Core uses Illumina NextSeq 2000 sequencers (and a MiSeq). Single-cell (fresh, frozen, FFPE) libraries (3' & 5' RNA-Seq, CITE-Seq, ATAC-Seq, Multiome, FLEX) are made with 10X Chromium X.
Proper citation: Massachusetts General Hospital NGS Core Facility (RRID:SCR_026362) Copy
Micro and nanofabrication facility that offers range of processing and packaging capabilities including lithography, wet and dry etching, thin film deposition, dicing, wire bonding, metrology, and inspection.
Proper citation: Montana State University Montana Microfabrication Core Facility (RRID:SCR_026333) Copy
https://www.montana.edu/geospatial/what-we-do/index.html
Provides equipment and team support to the workflow of all things geo-spatial from primary data collection using suite of different sensors and platforms to analysis that includes:Advanced mapping and geo-spatial analysis that leverage Uncrewed Aerial Vehicle (UAV) or drone-based sensors that use LiDAR, hyperspectral, thermal, orthoimagery, and Structure from Motion; High precision mapping and analysis using GPS and GNSS; Acoustic Doppler Profiles of rivers, reservoirs, and lakes;Data visualization and cartography;Remote sensing using active and passive sensors;Geo-spatial analysis, data development, and management;High Performance Computing infrastructure that leverages all of the above using open source and proprietary software.
Proper citation: Montana State University Geospatial Core Facility (RRID:SCR_026332) Copy
https://www.montana.edu/nmrcorefacility/
Core provides open access availability to NMR spectroscopy instrumentation, training and sample preparation. Facility can be accessed individually or as full service center. NMR Facility has a total space of ~2,500 sq ft. divided among 3 rooms fully constructed with considerations for cooling, in-place floor dampening infrastructure and space for wet lab/sample preparation. Facility specializes in small molecule structure determination, small molecule characterization, biomolecular/protein structure determination, qualitative and quantitative NMR analysis, and small molecule purification from wide variety of sample sources.
Proper citation: Montana State University Nuclear Magnetic Resonance Core Facility (RRID:SCR_026334) Copy
https://www.benaroyaresearch.org/our-research/core-labs/cell-and-tissue-analysis-group
Core offers flow cytometry, imaging, and histology resources.Provides expertise in the fields of imaging, histology, and flow cytometry, physical space and instruments, critical support through the whole process, from hands-on training to experiment design and data analysis.
Proper citation: Benaroya Research Institute Cell and Tissue Analysis Group Core Facility (RRID:SCR_026327) Copy
Facility provides diverse range of equipment, expertise and training in field of biochemistry, molecular, structural and cellular biology. Facility consists of several research laboratories and support areas.
Proper citation: University College London Darwin Research Core Facility (RRID:SCR_026345) Copy
https://mcw.ilab.agilent.com/service_center/5443/?tab=about
Institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy. OCAM-EM encompasses both Light and Electron Microscopy services.
Proper citation: Medical College of Wisconsin Oxford Instruments Center for Advanced Microscopy Electron Microscopy Core Facility (RRID:SCR_026315) Copy
https://sites.google.com/ualberta.ca/phhl/home
Core to advance understanding of mechanism of vascular dysfunction in chronic disease, identify how vascular dysfunction contributes to exercise intolerance, evaluate how exercise training improves vascular dysfunction and exercise intolerance using innovative clinical trial designs.
Proper citation: University of Alberta Precision Human Health Laboratory Core Facility (RRID:SCR_026314) Copy
https://www.unmc.edu/chvr/research/core-facilities/bioassay-core.html
Core provides equipment, personnel, and protocols for routine and advanced cellular and molecular assays for research.
Proper citation: University of Nebraska Medical Center Bioassay Core Facility (RRID:SCR_026270) Copy
https://www.brandeis.edu/science/resources/electron-microscope/index.html
Facility offers preparation and visualization ranging from standard 2D EM methods to high resolution 3D cryo-EM. Instruments, training and assisted use are available for Brandeis faculty, staff, and lab members, as well as members of the broader scientific community, including other academic institutions and for-profit organizations.
Proper citation: Brandeis University Louise Mashal Gabbay Cellular Visualization Center Electron Microscopy Core Facility (RRID:SCR_026272) Copy
https://site.research.utexas.edu/cbrs/
Facility provides access to and operational support for easy-to-operate equipment for sample preparation and analysis, including gel imagers, plate readers, and qPCRs. They provide training on instrument operation and grant access for independent use after completed training.
Proper citation: University of Texas at Austin Shared Instrumentation Facility (RRID:SCR_026271) Copy
https://www.seattlechildrens.org/research/resources/behavioral-phenotyping-core/
Core dedicated to the protocol driven collection, analysis, and reporting of behavioral data using a blend of classic and innovative assays. Supports neuroscience, psychology, pharmacology, genetics, cancer, and development by providing advanced tools and expertise for the precise measurement and interpretation of behavior.
Proper citation: Seattle Childrens Research Institute Behavioral Phenotyping Core Facility (RRID:SCR_026371) Copy
https://www.augusta.edu/research/core/therapeutics-core.php
Core offers services including assay development, FDA-drug library screening, unbiased compound screening, high-content imaging and screening. Facility can empower researchers to repurpose existing FDA-approved drugs and discover new compounds for drug development. Provides affordable platform for discovering therapeutic targets and interventions, supporting drug development from target identification to screening and validation. Features HTS facilities, including Biomek i7 Liquid Handling system, Pherastar FSX plate reader, ImageXpress Micro Confocal, and Pala cell sorter.
Proper citation: Augusta University Therapeutics Core Facility (RRID:SCR_026475) Copy
https://cvvr.hms.harvard.edu/cvvr-research-program/#hiv-1-neutralizing-antibody-core
Core provides in vitro HIV-1 neutralizing antibody assay services. Serves as resource for assessing breadth and potency of HIV-1 neutralizing antibodies, and for characterizing neutralization phenotype of HIV-1 isolates. Investigators send monoclonal antibodies or serum samples from vaccinated or HIV-1-infected individuals to the core for in vitro testing using the validated TZM.bl neutralizing antibody assay. The core also has the capability to phenotype primary HIV-1 isolates for sensitivity to broadly neutralizing antibodies. GCLP-compliant, In vitro testing of monoclonal antibodies or seurm samples, Validated TZM.bl neutralizing antibody assay, Phenotoyping of primary HIV-1 isolates.
Proper citation: Harvard University School of Medicine BIDMC HIV-1 Neutralizing Antibody Core Facility (RRID:SCR_026484) Copy
Provides services and instrumentation including Illumina Next-Generation Sequencing, Single Cell Analysis and Spatial Transcriptomics. These techniques are developed and optimized by our lab scientists to deliver the highest-possible quality sequencing data from a wide variety of sample types such as peripheral blood, bone marrow, fresh frozen tissue and FFPE-derived tumor samples.
Proper citation: University of Texas Institute for Personalized Cancer Therapy Cancer Genomics Laboratory Core Facility (RRID:SCR_026469) Copy
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