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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scienceexchange.com/facilities/stem-cell-core-facility-usc
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. USC Stem Cell Core facility is a CIRM funded comprehensive support center and central hub for the provision of knowledge, resources and state of the art technology to researchers working with stem cells. Our primary aims are to facilitate stem cell and biomedical research at USC and the LA area and to develop new technologies for working with pluripotent stem cells. We offer a wide range of services in the following areas: Cells and Reagents Reproducibility in experimental science is dependent on homogeneity and consistency. One of the primary aims of the USC Stem Cell Core is to standardize stem cell research by providing quality controlled cells and reagents. Equipment The USC Stem Cell Core is a shared laboratory space housing communal cell culture workstations, a state of the art imaging core, spectral karyotyping facilities, a Q-PCR machine, fully equipped molecular biology work stations and a variety of equipment for performing histological analysis. Flow cytometry and high content screening equipment are made available through the FACS core. Laboratory Space As a shared research facility we offer communal laboratory space for investigators to conduct collaborative or start up research involving stem cells. Our goal is to expand stem cell research in the LA area and to encourage collaboration between novice and seasoned researchers. Technical Assistance The USC Stem Cell Core is staffed with a team of highly experienced technicians, boasting a combined technical expertise of over 60 years. We provide comprehensive assistance, which includes a biobanking and histology service. Training and Education Training and education are pivotal to the advancement of Stem Cell Research. The USC Stem Cell Core offers a broad range of educational services including technical protocols, one on one customized training and a week long course covering human pluripotent stem cell culture techniques. Research and Development The USC Stem Cell Core Research and Development program was established with two main aims: 1) to develop and centralize new technologies for working with human pluripotent stem cells, 2) to support researchers embarking on collaborative and pilot projects.
Proper citation: USC Stem Cell Core Facility (RRID:SCR_012628) Copy
Alliance Protein Laboratories is a contract research and consulting firm specializing in biophysical analysis. We offer a broad and unique range of biophysical characterization services, as well as contract purification services (research scale) A.P.L. is a spin-off from the Protein Chemistry department at Amgen. It was founded in 1998 by Drs. Tsutomu Arakawa and John Philo. Our laboratory is located in San Diego, CA. Our clients include over 250 companies in North America, Europe, Asia, and Australia as well as major universities and non-profit institutes.
Proper citation: CSUCI Alliance Protein Laboratories (RRID:SCR_012592) Copy
http://www.scienceexchange.com/facilities/institute-for-biomolecular-design
The IBD provides a range of mass spectrometry and proteomic services such as protein identification and molecular weight determination. Additionally we also perform Amino Acid Analysis and Peptide Synthesis.
Proper citation: UAlberta Institute for Biomolecular Design (RRID:SCR_012591) Copy
http://www.scienceexchange.com/facilities/bioanalytical-service-laboratory
The BioAnalytical Service Laboratory at the Institute of Marine and Environmental Technology assists researchers by providing state-of-the-art instrumentation and training to conduct routine analytical, synthetic and separation projects.
Proper citation: UMD BioAnalytical Service Laboratory (RRID:SCR_012594) Copy
Provides or assists with docking and virtual screening of small molecule ligands against protein targets of interest, molecular dynamics simulation and modeling of small/macro molecules, proteins, and biomolecular systems, analysis of structure-activity relationships, visualization and graphics of biomolecules and biomolecular systems, and custom algorithm/software development along with databases and web applications.
Proper citation: University of Kansas Molecular Graphics and Modeling Laboratory Core Facility (RRID:SCR_012595) Copy
Nuclear Magnetic Resonance Laboratory is responsible for maintaining the high field NMR spectrometers, training users, providing spectra on a service basis, and assisting users with design, execution, and interpretation of NMR experiments. Our capabilities extend from small molecules to isotopically enriched proteins, semisolids, and flow samples. We are part of the Molecular Structures Group (MSG) at KU, a campuswide facility encompassing NMR, MS, X-ray Crystallography, Biochemical Service, and Molecular Graphics and Modeling Laboratories.
Proper citation: University of Kansas Nuclear Magnetic Resonance Laboratory Core Facility (RRID:SCR_012510) Copy
Core facility aides ISU investigators in the areas of molecular genetics, microbiology, developmental biology, physiology, anatomy, neurobiology, molecular evolution and systematics, phylogenetics, population genetics, bioinformatics, comparative and computational genetics, and pharmaceutical sciences. In addition the MRCF also serves the DNA sequencing and genotyping needs of an increasing number of investigators at other institutions throughout the state and the nation. Routine activities in the MRCF include automated DNA sequencing and microsatellite analysis (Genotyping), PCR, electrophoresis, and gel documentation and analysis.
Proper citation: Idaho State University Molecular Research Core Facility (RRID:SCR_012598) Copy
The High Throughput Gene Expression/Biomarker Core Laboratory run by Drs. Tanriverdi and Freedman provides High Throughput/Rapid Gene Expression and Complete miRNA profiling analysis by using gold standard qRT-PCR with the combination of custom Integrated Fluidic Circuit (IFC) technology from Fluidigm (South San Francisco, CA). Also, high-throughput SNP and multi-plate immunoassay services are available. The core lab is located in a modular class 10,000 clean room.
Proper citation: UMass Medical School High Throughput Gene Expression/Biomarker Core Laboratory (RRID:SCR_012631) Copy
http://www.scienceexchange.com/facilities/protein-core-facility-columbia
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Columbia University Protein Core Facility provides a range of services to all Columbia researchers and to outside users, including mass spectrometry, protein sequencing, and DNA sequencing. Mass Spectrometry: Services available include protein identification from gel bands or spots by MALDI-TOF and ESI-LC-MS/MS, post-translational modification identification, and mass analysis of intact proteins. Mass spectrometry is used to identify interacting partners in protein complexes that have been purified by immunoprecipitation and other methods. The Core also routinely provides structural confirmation of expressed proteins and protein fragments for structural biology studies. Protein Sequencing: N-terminal sequencing of proteins in solution or blotted to PVDF membranes is available. DNA Sequencing: The core offers high quality, fast turnaround DNA sequencing of various types DNA - plasmids, PCR products, GC-rich templates, cosmids, and BACs. DNA sequencing results are distributed through a secure network server with automated email notification.
Proper citation: Columbia University Protein Core Facility (RRID:SCR_012597) Copy
http://www.scienceexchange.com/facilities/flow-cytometry-core-lab-umass
The Flow Cytometry Facility, located at UMass Medical School in Worcester, provides a wide variety of cytometry services for internal and external investigators with state-of-the-art sorting and analyzing capabilities. For analysis we currently have three 4-color FACSCaliburs, a 2 laser LSR II, a 4 laser LSRII and a 5 laser LSRII. Our cell sorters include a 3 laser Beckman Coulter MoFlo XDP hi-speed cell sorter, an all digital 3 laser 11 color FACSVantage DE DiVa sorter, a 19 parameter, 5 laser FACSAria, and a 14 parameter, 4 laser FACSAria dedicated to BSL3 cell sorting. Two LSR II''s and one Calibur are dedicated for investigator self use, after training is completed. We encourage all investigators to come to the main lab at S5-322 and learn how flow cytometry can be applied to your research. Rates are based per hour and billed in 15 minute increments. Training rates are based per person, per hour. Sorting includes a 1 hour setup fee unless there is a second sort on that instument that day, in which case each sort is billed 30 minutes for setup. BSL3 Sorting is billed 30 minutes for setup in all cases
Proper citation: UMass Medical School Flow Cytometry Core Lab (RRID:SCR_012630) Copy
http://www.scienceexchange.com/facilities/gene-microarray-shared-resource-gmsr-ohsu
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The OHSU Gene Microarray Shared Resource (GMSR) functions as a full-service genomics facility serving research scientists and clinicians with DNA microarray services for RNA expression profiling and DNA variation analysis on two microarray platforms, Affymetrix and Illumina. Support for RNA isolation and RNA/DNA quality assessment also available
Proper citation: OSHU Gene Microarray Shared Resource (RRID:SCR_012512) Copy
http://www.scienceexchange.com/facilities/nicholson-lab
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15, 2024. Molecular physio-chemical processes in metabolism and medicine. Development of novel spectroscopic and chemometric tools for investigating human disease and toxicological mechanisms. Metabolism-driven top-down systems biology and modelling of complex system failure. Personalised healthcare through metabolic phenotyping. Surgical metabonomics, real-time diagnostics and integrative patient modelling.
Proper citation: Imperial College London Nicholson Lab (RRID:SCR_012511) Copy
http://www.scienceexchange.com/facilities/small-molecule-screening-facility-smsf-umass
Screening facility assists researchers in developing high-throughput screening assays, performs HT screens of chemical libraries to identify new small molecules that can be used to probe biological processes of interest. Facility coordinates screening efforts of UMass Chan researchers, providing access to diverse chemical libraries and state-of-the art instruments including robotic compound transfer, liquid-handling equipment, imagers and plate readers.
Proper citation: University of Massachusetts Medical School Small Molecule Screening Core Facility (RRID:SCR_012632) Copy
http://www.scienceexchange.com/facilities/electron-microscopy-core-facility-umass
The electron microscopy core facility provides services and expertise in all aspects of transmission and scanning electron microscopy. Services include conventional fixation and sectioning of cells and tissues, negative staining of organelles and macromolecular assemblies, shadowing of isolated protein molecules, freeze-fracture, immunolabeling, etc. Cryo-sectioning and cryo-electron microscopy are also available. Expert consultation on all aspects of experimental planning and micrograph interpretation is provided by the facility manager, Greg Hendricks.
Proper citation: UMass Medical School Electron Microscopy Core Facility (RRID:SCR_012634) Copy
http://www.scienceexchange.com/facilities/micro-nano-and-semiconductor-patterning
The ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.
Proper citation: ANFF Micro Nano and Semiconductor Patterning (RRID:SCR_012637) Copy
http://www.scienceexchange.com/facilities/nanoracks-u-s-national-lab
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 10th,2023. NanoRacks provides microgravity research facilities and currently includes NanoLab Platforms, NanoRacks Plate Reader, NanoRacks Microscope and NanoRacks MixStix.
Proper citation: NanoRacks (RRID:SCR_012608) Copy
Core facility that provides the following services: Microarray and other genomic data analysis, MiSeq. The Center provides broad-based support for the generation, analysis, and interpretation of genomic and other large-scale data in the context of basic, clinical and translational research. The CCCB has three primary elements. * The CCCB sequencing facility offers a wide range of services to assist in the design and execution of next-generation sequencing projects. Utilizing the Illumina (Solexa) sequencing technology, they currently support a number of applications inlcuding ChIP-Seq, RNA-Seq, whole genome, whole exome, and targeted re-sequencing. * The analytical services and support platform aims to provide state-of-the-art assistance in the collection, management, analysis, and interpretation of large-scale data with a focus on data generated using ''''omic technologies. In addition, they offer software, services, and training designed to assist investigators in advancing their research. * The CCCB research program is focused on development of new methods for improving analysis and interpretation of genomic data through integration of diverse data types with the goal of creating open-source software tools to be made freely-available to the research community.
Proper citation: DFCI Center for Cancer Computational Biology (RRID:SCR_012688) Copy
http://www.ohri.ca/stemcore/Default.aspx
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.
Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy
http://www.scienceexchange.com/facilities/specialist-device-fabrication
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. The ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.
Proper citation: ANFF Specialist Device Fabrication (RRID:SCR_012689) Copy
http://www.scienceexchange.com/facilities/high-resolution-plant-phenomics-centre-hrppc-csiro
The High Resolution Plant Phenomics Centre (HRPPC) is the Canberra node of the Australian Plant Phenomics Facility and is located in Canberra at CSIRO Plant Industry and the Australian National University. This centre focuses on _������_deep phenotyping_���� (delving into metabolism and physiological processes within the plant) and _������_reverse phenomics_���� (dissecting traits to discover their mechanistic basis). Next generation research tools are applied to probe plant function and performance, under controlled conditions and in the field. Recent advances in robotics, imaging and computing are used in applying these technologies and scaling them from the single plant to the ecosystem level. Two levels of service are provided in the HRPPC. First, projects can be housed in the _������_Research Hotel_���� environment where screening systems can be developed using facility staff and resources then deployed in the facility and in the user''''s home institution. Second, users_������_ material can be screened for specific attributes using one or more of the modules housed at CSIRO or the ANU. The HRPPC''''s focus is on flexibility from cereals to dicots and woody perennials at all stages of development.
Proper citation: CSIRO High Resolution Plant Phenomics Centre (RRID:SCR_012570) Copy
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