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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A database designed for plant comparative and functional genomics based on complete genomes. It comprises complete proteome sequences from the major phylum of plant evolution. The clustering of these proteomes was performed to define a consistent and extensive set of homeomorphic plant families. Based on this, lists of gene families such as plant or species specific families and several tools are provided to facilitate comparative genomics within plant genomes. The analyses follow two main steps: gene family clustering and phylogenomic analysis of the generated families. Once a group of sequences (cluster) is validated, phylogenetic analyses are performed to predict homolog relationships such as orthologs and ultraparalogs.
Proper citation: GreenPhylDB (RRID:SCR_002834) Copy
http://www.bioinformatics.nl/cgi-bin/primer3plus/primer3plus.cgi
A web interface to the Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3.
Proper citation: Primer3Plus (RRID:SCR_003081) Copy
http://www.fmrib.ox.ac.uk/fsl/
Software library of image analysis and statistical tools for fMRI, MRI and DTI brain imaging data. Include registration, atlases, diffusion MRI tools for parameter reconstruction and probabilistic taractography, and viewer. Several brain atlases, integrated into FSLView and Featquery, allow viewing of structural and cytoarchitectonic standard space labels and probability maps for cortical and subcortical structures and white matter tracts. Includes Harvard-Oxford cortical and subcortical structural atlases, Julich histological atlas, JHU DTI-based white-matter atlases, Oxford thalamic connectivity atlas, Talairach atlas, MNI structural atlas, and Cerebellum atlas.
Proper citation: FSL (RRID:SCR_002823) Copy
http://bibiserv.techfak.uni-bielefeld.de/dialign/
Tool for multiple sequence alignment using various sources of external information that is particularly useful to detect local homologies in sequences with low overall similarity. While standard alignment methods rely on comparing single residues and imposing gap penalties, DIALIGN constructs pairwise and multiple alignments by comparing entire segments of the sequences. No gap penalty is used. This approach can be used for both global and local alignment, but it is particularly successful in situations where sequences share only local homologies. Several versions of DIALIGN are available online at GOBICS, http://dialign.gobics.de/
Proper citation: DIALIGN (RRID:SCR_003041) Copy
https://github.com/WorkflowConversion/CTDopts
Software gives your command-line tools a CTD-compatible interface. Module for enabling tools with CTD reading/writing, argument parsing, validating and manipulating capabilities.
Proper citation: CTDopts (RRID:SCR_023997) Copy
https://github.com/jkbonfield/htscodecs/
Software repository implements the custom CRAM codecs used for "EXTERNAL" block types.Custom compression for CRAM custom algorithm written to compress the BAM file format for DNA sequencing data.
Proper citation: Htscodecs (RRID:SCR_024034) Copy
https://github.com/conda/conda-package-handling
Software to create and extract conda packages of various formats.
Proper citation: conda-package-handling (RRID:SCR_023991) Copy
http://www.cbcb.umd.edu/software/ELPH/index.shtml
Software tool as general purpose Gibbs sampler for finding motifs in set of DNA or protein sequences.Takes as input a set containing sequences, and searches through them for the most common motif, assuming that each sequence contains one copy of the motif. Used to find patterns such as ribosome binding sites (RBSs) and exon splicing enhancers (ESEs).
Proper citation: ELPH (RRID:SCR_024011) Copy
https://github.com/PacificBiosciences/unanimity
Software to generate highly accurate single molecule consensus reads.
Proper citation: CCS (RRID:SCR_024379) Copy
https://github.com/cancerit/alleleCount
Software package to prevent code duplication. Support code for NGS copy number algorithms. Generates count of coverage of each allele ACGT at that location given any filter settings.
Proper citation: alleleCount (RRID:SCR_023961) Copy
https://github.com/mateidavid/fast5
Software C++ library for accessing Oxford Nanopore Technologies sequencing data.
Proper citation: Fast5 Library (RRID:SCR_024023) Copy
Software provides command line interface and Python API for working with Biological Observation Matrix files.
Proper citation: python-biom-format (RRID:SCR_024193) Copy
http://sourceforge.net/projects/bait/
Software to create strand inheritance plots in data derived from the Strand-Seq sequencing protocol. The software is designed to be flexible with a range of species, and basic template folders can called to read in species-specific data.
Proper citation: BAIT (RRID:SCR_000511) Copy
http://www.atgc-montpellier.fr/mpscan/
Web tool for index free mapping of multiple short reads on a genome.
Proper citation: MPscan (RRID:SCR_000587) Copy
A tool for creating logos representing both sequence alignments and profile hidden Markov models. The interactive logos enable scrolling, zooming, and inspection of underlying values. Skylign can avoid sampling bias in sequence alignments by down-weighting redundant sequences and by combining observed counts with informed priors. It also simplifies the representation of gap parameters, and can optionally scale letter heights based on alternate calculations of the conservation of a position.
Proper citation: Skylign (RRID:SCR_001176) Copy
http://ccb.jhu.edu/software/sim4cc/
Software tool as cross species spliced alignment program.Heuristic sequence alignment tool for comparing cDNA sequence with genomic sequence containing homolog of gene in another species.
Proper citation: sim4cc (RRID:SCR_001204) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/bsseq.html
R package with tools for analyzing and visualizing bisulfite sequencing data.
Proper citation: bsseq (RRID:SCR_001072) Copy
https://omictools.com/splitseek-tool
THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data.
Proper citation: SplitSeek (RRID:SCR_001012) Copy
http://sourceforge.net/projects/autoassemblyd/
Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers.
Proper citation: AutoAssemblyD (RRID:SCR_001087) Copy
http://www.well.ox.ac.uk/happy/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package for Multipoint QTL Mapping in Genetically Heterogeneous Animals (entry from Genetic Analysis Software) The method is implemented in a C-program and there is now an R version of HAPPY. You can run HAPPY remotely from their web server using your own data (or try it out on the data provided for download).
Proper citation: Happy (RRID:SCR_001395) Copy
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