Tools   Select Another Resource Report Type

http://www.scienceexchange.com/facilities/electron-microprobe-laboratory

An electron microprobe is an electron microscope designed for the non-destructive x-ray microanalysis and imaging of solid materials. It is capable of high spatial resolution (1 micron beam size) and relatively high analytical sensitivity. The analytical facilities'''' JEOL JXA-8600 can acquire digital secondary-electron and backscattered-electron images as well as elemental x-ray maps. It is equipped with 4 wavelength-dispersive spectrometers and an energy-dispersive spectrometer. Most of the periodic table can in principle be analyzed (Be through U), subject to several important considerations. The quality of analyses performed depends essentially on the quality of sample preparation, character of the sample material, and availability of appropriate primary and secondary calibration standards for the desired elements. A precision usually less than 0.5% relative depending on element abundance, and accuracy as good as 1-2% can be obtained with this instrument. The analytical sensitivity ranges from a low of ~50 parts per million for optimum cases, to a typical detection limit of several hundred ppm, but can be as high as several weight percent for problem elements. The volume sampled is typically a few cubic microns, corresponding to a weight of a few picograms.

Proper citation: CU Boulder Electron Microprobe Laboratory (RRID:SCR_012321) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/embryonic-stem-cell-core

The Murine Embryonic Stem Cell Core has been created to help you create mutations in murine embryonic stem cells. The core has several missions including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. The core utilizes quality-controlled cells developed here at Washington University.

Proper citation: WUSTL School of Medicine Embryonic Stem Cell Core (RRID:SCR_012441) Copy   

•   Source: SciCrunch Registry

http://cancer.dartmouth.edu/res/transgenics_genetic.html

Core facility that provides the following services: Cigarette smoke exposure analysis service, Oocyte injection for transgenic animal production, Transgenic mice consultation, Generation of chimeric mice from ES cells, Transgenic lines establishment, Genotyping service, Tail biopsies and other services, Humanized mice production. The mission of the TGCSR is to support the generation and utilization of genetically modified mice by members of the Dartmouth research community. The support starts with intellectual support in planning and designing transgenic experiments provided by consultation with the TGCSR director. The TGCSR is now able to offer not only assistance with design of genetic constructs but also the production of genetic constructs for use in transgenic animal production through recombineering in either yeast or E. coli. TGCSR provides a full range of ES cell manipulation services. The tasks of manipulating the mouse embryo are fully provided by the TGCSR either in house or through an established relationship with the University of Vermont. Jackson labs is now providing cryopreservation services to protect and preserve valuable transgenic mouse lines. The TGCSR can also provide genotyping and mouse husbandry services. As currently organized, the TGCSR can provide the full range of services required to design, generate and maintain transgenic mouse lines. TGCSR currently maintains two specialized transgenic lines that express Cre or Flp in the germline for genetic manipulation of transgene/knockouts in vivo. TGCSR has a fully equipped embryo manipulation laboratory in the Borwell animal facility and an adjoining 4 room suite of mouse husbandry rooms.

Proper citation: Dartmouth Transgenics and Genetic Constructs Shared Resource (RRID:SCR_012443) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/histopathology-and-tissue-shared-resource-georgetown

The HTSR offers a full complement of histology services through our combined Human Tissue Bank, histology, and IHC departments. The Human Tissue Bank supports tissue procurement and the retrieval of fresh frozen and archival paraffin blocks. The Histology laboratory provides processing, embedding and microtomy services both for fresh frozen and fixed tissues. The Histology lab also provides numerous routine and non-routine histological stains. The Immunohistochemistry (IHC) laboratory supports colorimetric and fluorescent IHC staining for established antibodies as well as the development of protocols for new antibodies. The IHC lab also supports TUNEL labeling and novel labeling techniques.

Proper citation: Georgetown Histopathology and Tissue Shared Resource (RRID:SCR_012489) Copy   

•   Source: SciCrunch Registry

https://rtsf.natsci.msu.edu/genomics/gene-expression-analysis/index.aspx

RTSF Genomics Core offers services for investigators looking to utilize gene expression for their research. Our range of applications includes solutions for quantifying gene expression levels in nearly any species regardless of sample size. Services include Next Generation Sequencing using Illumina instruments, qPCR using the ABI QuantStudio 7 Flex Real-Time PCR System, and gene expression using NanoString nCounter system.

Proper citation: Michigan State University RTSF Genomics Core Facility (RRID:SCR_012406) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/experimental-pathology-core-laboratory-uark

The Experimental Pathology Shared Resource Laboratory is a non-profit laboratory that provides investigators with centralized, comprehensive histological services. The laboratory currently works with over 70 investigators at the University of Arkansas, regionally, and nationally. By providing a centralized laboratory, we offer convenient access to all services within one facility, save costs for investigators and the institution, increase efficiency of sample processing, eliminate duplication of services and equipment, and maintain stringent quality control standards. The laboratory director, consultants, and technicians have extensive experience in routine histology and immunohistochemistry involving both human and animal tissues.

Proper citation: UAMS Experimental Pathology Core Laboratory (RRID:SCR_012373) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genoseq-core-facility-ucla

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Core is involved in a broad range of scientific research. Medical research performed at the GenoSeq Core includes studies of human neurological disorders, such as: autism, bipolar disorder, and epilepsy; cancers of breast, colon, lung, and prostate; cardiac disease; and digestive disorders. Core also carries out studies of the genetics of non-human organisms. The GenoSeq Core is closely linked to the UCLA Bioinformatics Core in Gonda Center, which provides the computing power and sophisticated software needed to analyze and interpret the unprecedented volume of genetic data being generated with modern laboratory automation.

Proper citation: University of California Los Angeles GenoSeq Core Facility (RRID:SCR_012411) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/microarray-resource-core-bu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Microarray Resource Core offers the full line of microarray products available from Affymetrix. This includes expression profiling, miRNA, exon, genotyping, resequencing, and tiling arrays. As part of our standard service, the resource provides assistance with experimental design and data analysis. Arrays for other organisms are available; please contact us for with specific requests.

Proper citation: Boston University Microarray Resource Core (RRID:SCR_012491) Copy   

•   Source: SciCrunch Registry

https://genomics.umn.edu/

Provides genomic technologies and services to researchers and clinicians. Services include Next Generation Sequencing, Epigenomics, SARS-CoV-2 services, GBS, Third Generation Sequencing, NGS Library Creation, Sanger Sequencing, DNA and RNA Extraction, Gene Expression.

Proper citation: University of Minnesota Genomics Center Core Facility (RRID:SCR_012413) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/animal-and-food-sciences-department-udel

We offer a wide range of disciplines including virology, physiology, nutrition, microbiology, immunology, molecular biology, engineering, and genomics. Our research addresses contemporary and future scientific challenges by using cutting edge technologies with the goal of assisting stakeholders in the poultry, livestock, and food industries.

Proper citation: UD Animal and Food Sciences Department (RRID:SCR_012415) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-of-biomedical-analysis-tsinghua-university

The center of biomedical analysis (CBA) is a multiple discipline platform. CBA is bound to provide the best services and support to our investigators in all research fields. We welcome any suggestions and recommendations. In consultation with the Advisory Committee for each facility, the facility manager sets up the fee structures and makes decision on equipment purchase and upgrade.

Proper citation: Tsinghua University Center of Biomedical Analysis (RRID:SCR_012382) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-biophysical-sciences-and-engineering-cbse

Since 1986, The Center for Biophysical Sciences and Engineering (CBSE) has integrated our strengths to become a leading structural biology center capable of embracing the _������������_genes to drug_���� paradigm. We are one of the world''''s largest Structure Based Drug Discovery facilities with over 110 employees, including 15 Ph.D. level crystallographers. The CBSE is centered on a suite of integrated high throughput laboratories allowing us to offer a cost-effective platform of discovery services designed to increase the efficiency and success for drug discovery projects with industry, academic and government partners.

Proper citation: UAB Center for Biophysical Sciences and Engineering (RRID:SCR_012509) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-core-facility-uchicago

Flow Cytometry Facility at the University of Chicago is committed to providing the highest quality services to all its investigators.

Proper citation: UChicago Flow Cytometry Core Facility (RRID:SCR_012508) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-microarray-core-facility-duke

The Duke Microarray Facility provides services for the analysis of gene expression. The facility is operated jointly with the Duke Cancer Institute and provides: Affymetrix Microarrays Agilent Microarrays Real-Time PCR RNA Quality Check with Agilent Bioanalyzer The Microarray Facility also maintains a comprehensive database server to manage the massive amounts of data generated by microarray analysis. The facility provides data analysis support through various software packages as well as gene annotation support.

Proper citation: Duke DNA Microarray Core Facility (RRID:SCR_012629) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/w-m-keck-biomedical-mass-spectrometry-laboratory-virginia

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. W.M. Keck Biomedical Mass Spectrometry Laboratory within the Biomolecular Research Facility identifies and analyzes proteins from gels and solution using current mass spectrometry techniques. There are techniques to compare samples which have different amounts of the same proteins. Analyses available: - Protein identification and sequencing from gel or solution by either peptide mass fingerprinting or ESI-LC/MS/MS at the low femtomole level. - Analysis of protein mixtures such as tissue and media analysis of tissue samples prepared by Laser Capture Microdissection - Proteomics, comparison of proteins in tissue samples using chemical/isotopic labels or label free analysis - Absolute quantitation of proteins using labeled peptides and selective reaction monitoring - Identification of phosphorylation sites using titanium dioxide enrichment - Identification of post-translational modifications (deamination, ubiquitination, etc) - De Novo (manual) sequence analysis of novel proteins to obtain sufficient sequence data for cloning - High resolution, high mass accuracy measurements of peptides and small proteins - Confirmation of peptide identity by MALDI mass measurements - Identification of binding partners Equipment Our current mass spectrometers: - Thermo Scientific LTQ Orbitrap Velos for high accuracy, high sensitivity analysis - Bruker Microflex for mass analysis by MALDI - Thermo Scientific TSQ Quantum Access MAX triple quadrupole instrument Sample types analyzed: - gel bands, stained with Coomassie, silver, fluorescent stains - proteins in solution - tissue samples - media - Laser Capture Microdissection tissue samples.

Proper citation: UVa W.M. Keck Biomedical Mass Spectrometry Laboratory (RRID:SCR_012589) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/advanced-optical-microscopy-facility

The Advanced Optical Microscopy Facility (AOMF) is centrally located in the Discovery District in Toronto, Ontario, serving University Health Network as well as external academic and industrial users. It is the largest microscopy facility in Canada with instruments at Princess Margaret Hospital and Toronto General Hospital. With over 30 instruments and 4 staff members, the AOMF is equipped to help you with nearly any optical microscopy application including: confocal, multiphoton, FRAP, FRET, live-cell, timelapse, spectral unmixing, in-vivo bioluminescence and fluorescence, whole-slide scanning, 3D rendering, colocalization and more. We offer: Free consultations to determine which microscopes would best suit your application Comprehensive training and support on our various instruments Full-service image capture and analysis (a great way to get started quickly) High-resolution whole slide scanning service for histology slides Practical courses on microscopy, including one-on-one hands-on sessions (eg: Fundamentals of Microscopy) and larger workshops tailored to your group''''s applications Software and training for image processing and quantification

Proper citation: UHN Advanced Optical Microscopy Facility (RRID:SCR_012622) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/MSF/Proteomics/

The University of Massachusetts Medical School Proteomics and Mass Spectrometry Facility is an analytical laboratory resource offering state-of-the-art proteomic, lipid, and small molecule mass spectrometric analyses to both the academic and external scientific community. This includes resources for study design, sample preparation and cleanup, sample fractionation, instrumentation, informatics, data interpretation, and publication assistance.

Proper citation: UMMS Proteomics and Mass Spectrometry Facility (RRID:SCR_012500) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-microarray-core-facility-ualbany

Core provides microarray services for Affymetrix GeneChip arrays, Agilent microarrays, NimbleGen microarrays and custom-produced spotted cDNA microarrays. Projects developed through DNA Microarray Center have made use of arrays from variety of genomes, eukaryotic, prokaryotic, and plant. Core services includes RNA/DNA isolation, gene expression, miRNA, Chip-chip, Rip-chip and DNA methylation services. Provides bioinformatics tools for further analysis of results of expression experiments.

Proper citation: University at Albany Center for Functional Genomics DNA Microarray Core Facility (RRID:SCR_012502) Copy   

•   Source: SciCrunch Registry

https://www.mcgill.ca/cian/

Core facility at Biology Department in McGill Faculty of Science. Expertise in Light Microscopy and Image Analysis. Provides light microscopes, ranging from Point Scanning and Spinning Disc Confocals to Multi-Photon, TIRF, Light Sheet and Super-Resolution microscopes. Provides services in Automation/High throughput screening (liquid handler, pinning robot), Protein expression and antibody production. Users get training.

Proper citation: McGill Cell Imaging and Analysis Network Core Facility (RRID:SCR_012623) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cellular-and-molecular-biology-core-uvm

This is a free facility for everyone at the University of Vermont; however, preference will be given to the principle investigators listed on the COBRE grant, followed by members of the neuroscience community and finally, the university as a whole. Check in advance when planning experiments to determine space and equipment availability.

Proper citation: UVM Cellular and Molecular Biology Core (RRID:SCR_012505) Copy   

•   Source: SciCrunch Registry