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http://www.bioconductor.org/packages/devel/bioc/html/DMRforPairs.html
Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance.
Proper citation: DMRforPairs (RRID:SCR_005702) Copy
The Pr��ncipe Felipe Research Centre (CIPF), which was inaugurated by their Royal Highnesses the Prince and Princess of Asturias on 17th March 2005, is a centre dedicated to biomedical research, with the aim of taking on new challenges in the field of basic research and encouraging scientific works of excellence. The construction of the Centre was carried out thanks to the Regional Development Funds from the European Union, and from the Regional Government (Generalitat Valenciana) through its Ministry of Health. The current financing of the CIPF comes mainly from the investment made by the Generalitat Valenciana through the Ministry of Health, as well as the Regenerative Medicine Programme, the fruit of an agreement between the Institute of Health Carlos III and the Ministry of Health for basic and translation research in this field. The CIPF takes the research tradition from the then Valencian Cytological Research Institute and the Valencian Biomedical Research Foundation, with the aim of consolidating and expanding this research. Therefore the activity in the CIPF can be divided into three main strategic work areas: The Regenerative Medicine area focuses its research on cellular therapy and interdisciplinary research in human embryonic and adult stem cells, with the aim of regenerating damaged organs to improve human health. The Chemical and Quantative Biology area aims to understand, through the application of (bio) chemical, genetic, and bioinformatic methods, to understand the molecular mechanisms that control the biological processes and alterations that lead to pathological conditions. The Biomedicine area focuses on understanding the molecular bases of human pathologies that require new diagnostic and clinical procedures for their identification and treatment, pathologies such as cancer, neurological pathologies and rare illnesses.
Proper citation: Principe Felipe Research Centre; Valencia; Spain (RRID:SCR_005691) Copy
http://www.vicbioinformatics.com/software.vague.shtml
An open-source de novo genome assembly software tool, which is run from the Unix command line, providing a multi-platform graphical front-end for the Velvet de novo assembler. VAGUE is implemented in JRuby and targets the Java Virtual Machine.
Proper citation: VAGUE (RRID:SCR_005607) Copy
http://www.bioinformatics.babraham.ac.uk/projects/bismark/
Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step.
Proper citation: Bismark (RRID:SCR_005604) Copy
https://code.google.com/p/jmhc/
Software for analyzing and visualization of the results of deep amplicon sequencing.
Proper citation: jMHC (RRID:SCR_005605) Copy
http://genome-www.stanford.edu/TMA/combiner/
A Simple Software Tool to Permit Analysis of Replicate Cores on Tissue Microarrays., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: TMA-Combiner (RRID:SCR_005600) Copy
http://tmaj.pathology.jhmi.edu/
Open-source software to support information and images related to tissue micro-arrays. It contains support for multiple organ systems, multiple users, image analysis, and is designed to be compliant with HIPPA regulations. Patients, specimens, blocks, slides, cores, images, and scores can all be stored and viewed. Features include advanced security, custom dynamic fields, and an image analysis program.
Proper citation: TMAJ (RRID:SCR_005601) Copy
http://agbase.msstate.edu/cgi-bin/tools/goprofiler_select.pl
Service that provides a summary of GO annotations available for each species. The user provides a taxon id and GOProfiler displays the number of GO associations and the number of annotated proteins for that species. The results are listed by evidence code and a separate list of unannotated proteins is also provided.
Proper citation: GOProfiler (RRID:SCR_005683) Copy
http://www.eie.gr/index-en.html
The National Hellenic Research Foundation (NHRF) is a multidisciplinary Research Centre established by Royal Decree on 9th October 1958. Its purpose is the organisation, finance and support of high-level research projects in the humanities and the natural sciences. The Humanities Institute cover a wide spectrum of study and research fields in Greek history and culture, contributing substantially and critically to the knowledge and promotion of Greek identity. The Natural Sciences Institutes perform basic and applied research in leading edge areas of science such as health, pharmaceuticals, environment, biotechnology and new materials. They develop innovative methods for solving complex problems facing Greek industry and they provide specialised services and know-how both to the public and private sector. The NHRF is governed by the Board of Directors and the Central Administration under the Director/Chairman of the Board.
Proper citation: National Hellenic Research Foundation (RRID:SCR_005719) Copy
http://genome-www.stanford.edu/TMA/
Software Tools for High-Throughput Analysis and Archiving of Immunohistochemistry Staining Data Obtained with Tissue Microarrays.
Proper citation: Stanford TMA Software (RRID:SCR_005598) Copy
http://www.compbio.dundee.ac.uk/downloads/oxbench/
A suite of programs aimed at developers of alignment methods rather than end-users to assess the accuracy of multiple sequence alignment methods. It includes a reference database of protein multiple sequence alignments that were generated by consideration of protein three-dimensional structure.
Proper citation: OXBench (RRID:SCR_005591) Copy
http://staden.sourceforge.net/
A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows.
Proper citation: Staden Package (RRID:SCR_005629) Copy
http://mesquiteproject.org/packages/chromaseq/
A software package in Mesquite that processes chromatograms, makes contigs, base calls, etc., using in part the programs Phred and Phrap.
Proper citation: Chromaseq (RRID:SCR_005587) Copy
The Burroughs Wellcome Fund is an independent private foundation dedicated to advancing the biomedical sciences by supporting research and other scientific and educational activities. Within this broad mission, BWF has two primary goals: * To help scientists early in their careers develop as independent investigators * To advance fields in the basic biomedical sciences that are undervalued or in need of particular encouragement BWF''s financial support is channeled primarily through competitive peer-reviewed award programs. * BWF''s endowment: $586.8 million at the end of FY 2009 * BWF approved $26.4 million in grants during FY 2009 BWF makes grants primarily to degree-granting institutions on behalf of individual researchers, who must be nominated by their institutions. To complement these competitive award programs, BWF also makes grants to nonprofit organizations conducting activities intended to improve the general environment for science. A Board of Directors comprising distinguished scientists and business leaders governs BWF. BWF was founded in 1955 as the corporate foundation of the pharmaceutical firm Burroughs Wellcome Co. In 1993, a generous gift from the Wellcome Trust in the United Kingdom, enabled BWF to become fully independent from the company, which was acquired by Glaxo in 1995. BWF has no affiliation with any corporation.
Proper citation: Burroughs Wellcome Fund (RRID:SCR_005772) Copy
http://www.cancer.fi/syoparekisteri/en/
The Finnish Cancer Registry maintains a nation-wide database on all cancer cases in Finland going back to 1953. It is also an internationally active institute for statistical and epidemiological cancer research. The Mass Screening Registry is a department of the Finnish Cancer Registry, and is responsible of planning and evaluating national cancer screening programs in Finland. The site contains information on cancer research and up to date statistics on the prevalence of different types of cancer in Finland, the Nordic countries and on a global level. The web pages include information for participants in cancer screening and for professionals involved in organizing such screening.
Proper citation: Finnish Cancer Registry (RRID:SCR_005881) Copy
http://snp-magma.sourceforge.net
Software that utilizes a multiobjective evolutionary algorithm for genetic mapping. It is based on a the ECJ evolutionary software package written by Sean Luke and includes the Strength Pareto Evoluationary Algorithm Version 2 changes for multiobjective analysis. The code runs on any platform with Java Version 2. A genetic mapping project, typically implemented during a search for genes responsible for a disease, requires the acquisition of a set of data from each of a large number of individuals. This data set includes the values of multiple genetic markers. These genetic markers occur at discrete positions along the genome, which is a collection of one or more linear chromosomes. Typing the value of a marker in an individual carries a cost; one seeks to minimize the number of markers typed without excessively jeopardizing the probability of detecting an association between a marker and a disease phenotype. MAGMA is a project which employ''s a multiobjective evolutionary algorithm to solve this problem.
Proper citation: MAGMA (RRID:SCR_005757) Copy
Icahn School of Medicine at Mount Sinai, formerly Mount Sinai School of Medicine, is graduate medical school in Manhattan, New York City. Leader in medical and scientific training and education, biomedical research and patient care.
Proper citation: Icahn School of Medicine at Mount Sinai; New York; USA (RRID:SCR_005793) Copy
http://www.ibridgenetwork.org/wustl/splinter
Software that detects and quantifies short IN/DELs as well as single nucleotide substitutions in pooled-DNA samples.
Proper citation: SPLINTER (RRID:SCR_005826) Copy
http://www.patternlabforproteomics.org/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented July 5, 2018. Gene Ontology Explorer (GOEx) combines data from protein fold changes with GO over-representation statistics to help draw conclusions in proteomic experiments. It is tightly integrated within the PatternLab for Proteomics project and, thus, lies within a complete computational environment that provides parsers and pattern recognition tools designed for spectral counting. GOEx offers three independent methods to query data: an interactive directed acyclic graph, a specialist mode where key words can be searched, and an automatic search. A recent hack included in GOEx is to load the sparse matrix index file directly into GOEx, instead of going through the report generation using the AC/T-fold methods. This makes it easy for GOEx to analyze any list of proteins as long as the list follows the index file format (described in manuscript) . Please note that if using this alternative strategy, there will be no protein fold information. Platform: Windows compatible
Proper citation: GOEx - Gene Ontology Explorer (RRID:SCR_005779) Copy
https://www.applichem.com/home/
An Antibody supplier
Proper citation: AppliChem (RRID:SCR_005814) Copy
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