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https://nbcc.lunenfeld.ca/facilities/flow-cytometry

Core provides flow cytometry analyzers and cell sorters, with specialty in image-based flow cytometry and cell sorting.Services include unassisted and full-service cell sorting, training on theory and on instruments, consultation on experiment design, protocol development, data analysis, manuscript preparation and grant submission. Applications include image-based analysis powered by machine learning on the Amnis ImageStream; image-based cell sorting using the BD BACS Discover S8; cell sorting for a variety of applications including multi-color sort for bulk culture, indexed cell sort into 96-well plates, cell cycle phase sort and primary tissue sorting for RNA or DNA analysis.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Flow Cytometry Core Facility (RRID:SCR_025384) Copy   

•   Source: SciCrunch Registry

https://nbcc.lunenfeld.ca/facilities/next-gen-sequencing

Core provides both short and long read sequencing capabilities for analysis of gene function and expression.Facility specializes in functional genomics and single cell biology. Services include consultation, sample preparation (especially for spatial and single cell applications), quality control, sequencing analysis, bioinformatics support, and assistance with grant and publication writing related to the services. Applications include:gene function analysis - pooled CRISPR screening, multiplexed barcode screens; whole genome sequencing - both short- and long-read sequencing; bulk gene expression profiling; single cell biology (single cells and single nuclei); spatial profiling; pathogen detection and profiling.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Next-Generation Sequencing Core Facility (RRID:SCR_025385) Copy   

•   Source: SciCrunch Registry

https://sites.dartmouth.edu/cqb/projects-and-cores/data-analytics-core/

Core offers statistical analysis of genomics data. Provides suite of standardized analysis pipelines for common data types like RNA-seq, ATAC-seq, and genome assembly. For more complex datasets, such as single-cell genomics, provides tailored analysis solutions. Core team assists with all project stages, from experimental design to publication support and data management. GDSC hosts several multi-day bioinformatics workshops designed to introduce fundamental concepts for analysis of genomics data.

Proper citation: Dartmouth Genomic Data Sciences Core Facility (RRID:SCR_025383) Copy   

•   Source: SciCrunch Registry

https://genomics.ed.ac.uk

Core is staffed and equipped to provide secure receipt, processing, archiving and analysis of biological samples. Our team can provide support for your clinical research from sample collection to genetic analysis, working to the principles of Good Clinical Practice for Laboratories.Facility provides access to genomic technologies and services including next-generation sequencing (Illumina), third-generation sequencing (PacBio and Oxford Nanopore), bespoke bioinformatics analysis, and genomics and bioinformatics training.

Proper citation: University of Edinburgh Genomics Core Facility (RRID:SCR_025433) Copy   

•   Source: SciCrunch Registry

https://nbcc.lunenfeld.ca/facilities/high-throughput-screening

Provides instrumentation and expertise for the automation of laboratory processes. Facility has automated screening platforms and accessory equipment to enable flexible and scalable in vitro and in vivo assays including organoids. Services include access to chemical and genome-wide siRNA libraries, assay development and implementation, and data analysis. Applications include drug discovery and lead validation; ELISA-based assays for immune surveillance; protein biomarker discovery using OLINK proteomics technology; multiplexed barcode screening assays.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre High-Throughput Screening Core Facility (RRID:SCR_025390) Copy   

•   Source: SciCrunch Registry

https://hillman.upmc.com/cancer-care/imcpl

Core operates 12 clean rooms and focuses on IND manufacturing under cGMP/cGTP. Operations are monitored 24/7 by expert staff. Specializes in and collaborates on preclinical research development involving process conceptualization, technology transfer and testing implementation on human cell-based drugs for clinical trials. Immunological monitoring services are available to support clinical trials. The facility is a FACT-, CLIA-, CAP-, and FDA-accredited laboratory.

Proper citation: University of Pittsburgh Hillman Cancer Center Immunologic Monitoring and Cellular Products Laboratory Core Facility (RRID:SCR_025362) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/in-vivo-imaging/

Provides novel quantitative imaging techniques that trace biomarkers of molecular events associated with effective cancer therapy.

Proper citation: University of Pittsburgh Hillman Cancer Center In Vivo Imaging Core Facility (RRID:SCR_025360) Copy   

•   Source: SciCrunch Registry

https://bioinformatics.sph.harvard.edu/

Provides single point of contact for Harvard researchers interested in bioinformatics support, applying genomic approaches together with established and developing methodologies from epidemiology, environmental health, biostatistics and bioinformatics to improve human health.Services include analysis all types of next-generation sequencing data from RNA-seq and single cell RNA-seq to variant sequencing (exome or whole genome), to ChIP-seq or bisulfite sequencing. Offers bioinformatics training program for Harvard researchers interested in learning basic data skills and analysis of high-throughput sequencing data.

Proper citation: Harvard University Chan School of Public Health Bioinformatics Core Facility (RRID:SCR_025373) Copy   

•   Source: SciCrunch Registry

https://mriresearch.med.ubc.ca/

Facility consist of Philips 3.0 Tesla MRI scanner for studies on humans, Bruker small bore 9.4 Tesla MRI scanner, and computing facility for image archival and analysis. Scanners are entirely dedicated to research, and MR scanning is carried out on cost recovery basis. The scanners were selected to cater to a very broad range of in vivo applications and the Imaging Centre staff is trained to support any research projects that the scanners can accommodate.

Proper citation: University of British Columbia MRI Research Core Facility (RRID:SCR_025374) Copy   

•   Source: SciCrunch Registry

https://www.ncl.ac.uk/bioimaging/

Light microscopy core facility at Newcastle University based in the Faculty of Medical Sciences, providing services, access, training and support for light microscopy.

Proper citation: Newcastle University Bioimaging Unit Core Facility (RRID:SCR_025354) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/biostatistics/

Provides statistical and computational methods for design, execution, analysis, and reporting of cancer-related research studies and trials including biomarker analysis and grant development.

Proper citation: University of Pittsburgh Hillman Cancer Center Biostatistics Core Facility (RRID:SCR_025355) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cancer-genomics/

Supports genomics and transcriptomics platforms including nucleic acid extraction, sample QC, next-generation library preparation and sequencing. Specializes in paraffin-embedded tissue samples.

Proper citation: University of Pittsburgh Hillman Cancer Center Cancer Genomics Core Facility (RRID:SCR_025357) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cancer-pharmacokinetics-and-pharmacodynamics/

Provides bioanalytical, pharmacokinetic and pharmacology research services that support preclinical and clinical research programs focused on oncology. Resources include HPLC-UV/fluorescence, ICP-MS, LC-MS/MS, LSC, ELISA, and in vivo rodent procedures, as well as advanced PK software suites and expertise for preclinical and clinical projects.

Proper citation: University of Pittsburgh Hillman Cancer Center Cancer Pharmacokinetics Pharmacodynamics Core Facility (RRID:SCR_025358) Copy   

•   Source: SciCrunch Registry

https://animalbehavior.indiana.edu/lab-resources/our-lab.html

Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.

Proper citation: Indiana University Bloomington CISAB Mechanisms of Behavior Laboratory Core Facility (RRID:SCR_025540) Copy   

•   Source: SciCrunch Registry

https://cryoem.bio.purdue.edu/

Facility provides access to instrumentation enabling users to collect data for high-resolution single particle reconstructions and tomographic studies of cells and larger complexes.

Proper citation: Purdue University Cryo-Electron Microscopy Core Facility (RRID:SCR_025545) Copy   

•   Source: SciCrunch Registry

https://crc.nd.edu/

CRC houses two complementary resources: the High-Performance Computing section, providing over 35,000 cores of computational power with the associated support infrastructure for both hardware and installed software, and the Cyberinfrastructure section, empowering Faculty and industry partners to develop research software and environments that support advanced data and information processing services including acquisition, storage, management, integration, mining

Proper citation: Purdue University Center for Research Computing Core Facility (RRID:SCR_025536) Copy   

•   Source: SciCrunch Registry

https://cancer.iu.edu/research/shared-facilities/cpac.html

Core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.

Proper citation: Indiana University School of Medicine Clinical Pharmacology Analytical Core Facility (RRID:SCR_025539) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/flow/index.php

Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.

Proper citation: Purdue University Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_025547) Copy   

•   Source: SciCrunch Registry

https://geneticslab.medicine.iu.edu/

Clinical testing lab that performs targeted metabolomics analyses designed to diagnose and manage patients with inherited metabolic disease.Services include Quantitative Acylcarnitine panel,Quantitative Amino acid panel,Quantitative Methylmalonic acid,Quantitative Free and Total Carnitine Analysis,Semi-Quantitative Urine Organic Acid Profile,Blood Spot Analyte Quantification,Custom Development of Quantitative Metabolite Assays.

Proper citation: Indiana University School of Medicine Biochemical Genetics Laboratory Core Facility (RRID:SCR_025523) Copy   

•   Source: SciCrunch Registry

https://indianactsi.org/servicecores/core/95/

Core collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. Facility comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL).

Proper citation: Indiana University School of Medicine Cell and Gene Therapy Manufacturing Core Facility (RRID:SCR_025531) Copy   

•   Source: SciCrunch Registry