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https://joslinresearch.org/drc-cores/Enrichment-Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Six component core which facilitates the exchange of research information and discussions among investigators, fellows and students within the Joslin Diabetes Center, as well as between Joslin Staff and outside researchers with similar interests.
Proper citation: Joslin Diabetes Center Enrichment Core (RRID:SCR_015094) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/gene-editing.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in Gene Editing Expertise Using CRISPR/CAS9, Conventional Transgenic Mouse Generation, Conventional Knockout, Knock-In Mouse Generation, and Cryopereservation of Sperm, Oocytes and Embryos.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Gene Editing Core (RRID:SCR_015091) Copy
Core that offers support for data-driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.
Proper citation: Joslin Diabetes Center Bioinformatics and Biostatistics Core (RRID:SCR_015092) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8, 2024. Core with main goal to steer investigators through introductory discovery lipidomics and proteomics experiments toward statistically powered, targeted experiments aimed at measuring biological pathways relevant to diabetes and metabolism.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Targeted Pathway Analysis Core Facility (RRID:SCR_015098) Copy
https://diabetescenters.org/cores/ucsd-ucla-transgenic-and-knockout-mouse-core
Core that provides and produces transgenic mice. Services and methodologies include pronuclear microinjection and blastocyst microinjection for creation of new mouse cell lines as well as archival services like embryo and sperm freezing.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Transgenic and Knockout Mouse Core Facility (RRID:SCR_015096) Copy
http://www.cure.med.ucla.edu/cores/animal-models
Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.
Proper citation: CURE - Digestive Diseases Research Center Animal Models Core (RRID:SCR_015217) Copy
http://cihd.cores.utah.edu/administration/
Core facility which oversees the operational and financial functioning of the CIHD. It aims include periodically reviewing current membership and selecting new members, monitoring administrative and scientific activities of the CIHD, and selecting projects to be funded through the Pilot and Feasibility Program.
Proper citation: Center for Iron and Heme Disorders at the University of Utah Administrative Core (RRID:SCR_015338) Copy
https://www.bcm.edu/research/centers/digestive-disease/core-facilities/administrative
Core that provides governance, financial and operational management, and strategic planning functions for the DDC. This core is also responsible for coordinating the annual Pilot Feasibility Awards program, as well as the weekly GI Research Forum and the annual Frontiers in Digestive Medicine Symposium.
Proper citation: Texas Medical Center Digestive Diseases Center Administrative Core (RRID:SCR_015222) Copy
https://ww2.mc.vanderbilt.edu/DDRC/6916
Core that aims to further digestive disease research by providing services including identification of oxidized lipids by GC/MS and HR-LC/MS, proteomics for identification and characterization of proteins by MudPIT and LC-MS/MS techniques, quantification of protein expression by LC-MS/MS, interpretation and analysis of mass spectrometry data, and quantification of trace elements in physiologic fluids by ICP-MS.
Proper citation: Vanderbilt Digestive Disease Research Center Bioanalytical Mass Spectrometry and Proteomics Core (RRID:SCR_015223) Copy
http://chicagodiabetesresearch.org/cores/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides support to investigators in designing and carrying out translational studies assessing outcomes for patients with diabetes, or populations at risk.
Proper citation: Chicago Center for Diabetes Translation Research Outcomes Improvement Core (RRID:SCR_015221) Copy
http://www.cancer.iu.edu/research-trials/facilities/in-vivo-core/index.shtml
Core facility which maintains on-site breeding colonies of mouse strains essential for study of murine and human hematopoietic cells in vivo. It also provides specialized core services and consultation to CHSCC investigators and serves as an educational resource for CHSCC laboratories.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Experimental Mouse Resources Core (RRID:SCR_015342) Copy
Core whose services include designing, constructing and validating custom plasmids and other DNA vectors, making custom genome engineering reagents, including TALENs, transposons, bacterial artificial chromosomes and CRISPRs, and providing consults and training on a variety of topics, including rodent and zebrafish transgenic and knockout model development support.
Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Gene Editing and Cell Engineering Core (RRID:SCR_015226) Copy
https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/
Core that provides instrumentation (confocal and fluorescence microscopy) and technical support for cell biology and pathophysiology studies.
Proper citation: USC Liver Transplant Program and Center for Liver Disease Cell and Tissue Imaging Core (RRID:SCR_015234) Copy
https://cdtr.wustl.edu/our-cores/dissemination-and-implementation/
Core facility whose services include consultion for further dissemination of diabetes research and assistance with design methods for early dissemination of results.
Proper citation: Washington University Center for Diabetes Translation Research Dissemination and Implementation in Diabetes Research Core (RRID:SCR_015230) Copy
http://www.baltimorepkdcenter.org/antibody/index.shtml
Core which supports the work of the Baltimore Polycystic Kidney Disease research center by providing antibody validation services and vectors to researchers.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core (RRID:SCR_015318) Copy
http://www.baltimorepkdcenter.org/mouse/index.shtml
Core facility which provides mouse models and a biobank of tissues and other materials for research.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank (RRID:SCR_015319) Copy
http://www.uab.edu/medicine/hrfdcc/cores/c
Core whose goals include to characterize mouse models of HRFD in vivo, establish mTERT and hTERT immortalized cell lines, and the physiological and molecular characterization of HFRD cell lines.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Cellular Physiology Resource (RRID:SCR_015316) Copy
http://medicine.yale.edu/labmed/ycceh/cores/core_a/index.aspx
Core facility which provides emerging technologies in hematology and relevant training for junior investigators. Its services include in vitro hematopoiesis assays services, automated complete blood counts, morpholoigcal analyses, CRISPR based genomic editing, and FACsorting and analysis.
Proper citation: Yale Cooperative Center of Excellence in Hematology Cell Preparation and Analysis Core (RRID:SCR_015317) Copy
http://sharedresources.fredhutch.org/core-facilities/antibody-technology
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides custom designed monoclonal antibodies made in mice, rats and rabbits. Services include design of antigens, immunization and screening strategies; hybridoma cell line production and optimization; and custom designed antibodies for biomarker discovery.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Antibody Technology (RRID:SCR_015322) Copy
http://medicine.yale.edu/labmed/ycceh/cores/core_b/index.aspx
Core facility which provides access to and training and consultation for imaging technology and platforms for hematology research.
Proper citation: Yale Cooperative Center of Excellence in Hematology Imaging Core (RRID:SCR_015325) Copy
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