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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
sSeq
 
Resource Report
Resource Website
10+ mentions
sSeq (RRID:SCR_001719) sSeq software resource Software package to discover the genes that are differentially expressed between two conditions in RNA-seq experiments. Gene expression is measured in counts of transcripts and modeled with the Negative Binomial (NB) distribution using a shrinkage approach for dispersion estimation. The method of moment (MM) estimates for dispersion are shrunk towards an estimated target, which minimizes the average squared difference between the shrinkage estimates and the initial estimates. The exact per-gene probability under the NB model is calculated, and used to test the hypothesis that the expected expression of a gene in two conditions identically follow a NB distribution. rna-seq, differential expression is listed by: OMICtools
has parent organization: Bioconductor
PMID:23589650 Free, Available for download, Freely available OMICS_01962 SCR_001719 sSeq - Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size 2026-02-07 02:05:34 46
RNASeqBias
 
Resource Report
Resource Website
RNASeqBias (RRID:SCR_001739) RNASeqBias software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10th,2023. An R software package for detecting and correcting biases in RNA-Sequencing data. rna-seq is listed by: OMICtools
has parent organization: Yale School of Medicine; Connecticut; USA
THIS RESOURCE IS NO LONGER IN SERVICE. OMICS_01957 SCR_001739 2026-02-07 02:05:42 0
pairedBayes
 
Resource Report
Resource Website
1+ mentions
pairedBayes (RRID:SCR_001738) pairedBayes software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10th,2023. An R code for Bayesian modeling of paired RNA-seq experiments. r, rna-seq is listed by: OMICtools
has parent organization: Yale School of Medicine; Connecticut; USA
THIS RESOURCE IS NO LONGER IN SERVICE. OMICS_01958 SCR_001738 2026-02-07 02:05:35 1
DNACLUST
 
Resource Report
Resource Website
1+ mentions
DNACLUST (RRID:SCR_001771) software resource Software program for clustering large number of short similar DNA sequences. It was originally designed for clustering targeted 16S rRNA pyrosequencing reads. cluster, dna sequence, gene, 16s rrna pyrosequencing read, microbiome is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
has parent organization: SourceForge
PMID:21718538
DOI:10.1186/1471-2105-12-271
Free, Available for download, Freely available OMICS_01955 https://sources.debian.org/src/dnaclust/ SCR_001771 DNAClust 2026-02-07 02:05:36 9
InterMine
 
Resource Report
Resource Website
10+ mentions
InterMine (RRID:SCR_001772) software resource An open source data warehouse system built for the integration and analysis of complex biological data that enables the creation of biological databases accessed by sophisticated web query tools. Parsers are provided for integrating data from many common biological data sources and formats, and there is a framework for adding data. InterMine includes a user-friendly web interface that works "out of the box" and can be easily customized for specific needs, as well as a powerful, scriptable web-service API to allow programmatic access to data. mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Cambridge; Cambridge; United Kingdom
Wellcome Trust PMID:24753429 Free, Freely available OMICS_03840, biotools:intermine https://github.com/intermine/intermine
https://bio.tools/intermine
http://intermine.github.io/intermine.org/ SCR_001772 2026-02-07 02:05:43 21
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-02-07 02:05:35 0
rlsim
 
Resource Report
Resource Website
rlsim (RRID:SCR_001703) rlsim software resource Software package for simulating RNA-seq library preparation with parameter estimation. rna-seq is listed by: OMICtools
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01965 SCR_001703 rlsim - a package for simulating RNA-seq library preparation with parameter estimation 2026-02-07 02:05:42 0
RSVSim
 
Resource Report
Resource Website
10+ mentions
RSVSim (RRID:SCR_001777) software resource A software package for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. SV breakpoints can be placed uniformly accross the whole genome, with a bias towards repeat regions and regions of high homology (for hg19) or at user-supplied coordinates. unix/linux, mac os x, windows, r, sequencing, structural variation is listed by: OMICtools
has parent organization: Bioconductor
PMID:23620362 Free, Available for download, Freely available OMICS_03822 SCR_001777 RSVSim: an R/Bioconductor package for the simulation of structural variations 2026-02-07 02:05:43 16
TCC
 
Resource Report
Resource Website
1+ mentions
TCC (RRID:SCR_001779) TCC software resource An R package that provides a series of functions for differential expression analysis from RNA-seq count data using robust normalization strategy (called DEGES). The basic idea of DEGES is that potential differentially expressed genes or transcripts (DEGs) among compared samples should be removed before data normalization to obtain a well-ranked gene list where true DEGs are top-ranked and non-DEGs are bottom ranked. This can be done by performing a multi-step normalization strategy (called DEGES for DEG elimination strategy). A major characteristic of TCC is to provide the robust normalization methods for several kinds of count data (two-group with or without replicates, multi-group/multi-factor, and so on) by virtue of the use of combinations of functions in other sophisticated packages (especially edgeR, DESeq, and baySeq). rna-seq, differential expression, high throughput sequencing is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: University of Tokyo; Tokyo; Japan
PMID:23837715 Free, Available for download, Freely available OMICS_01952 SCR_001779 Tag Count Comparison, TCC: Differential expression analysis for tag count data with robust normalization strategies 2026-02-07 02:05:35 8
CCAT
 
Resource Report
Resource Website
50+ mentions
CCAT (RRID:SCR_001843) CCAT software resource THIS RESOURCE IS OUT OF SERVICE, documented on April 5, 2017, A software package for the analysis of ChIP-seq data with negative control., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Genome Institute of Singapore; Singapore; Singapore
PMID:20371496 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00428, biotools:ccat https://bio.tools/ccat SCR_001843 Control based ChIP-Seq Analysis Tools 2026-02-07 02:05:45 76
Alt Event Finder
 
Resource Report
Resource Website
Alt Event Finder (RRID:SCR_001846) Alt Event Finder software resource Software tool for deriving data-driven alternative splicing (AS) events from RNA-seq data. It analyses the transcripts built by Cufflinks or Scripture and outputs AS event annotations which is compatible with MISO. It can be used for annotating novel AS events from a well-annotated species such as human. It can also be used for species of which known AS event annotation is not available. The current release (v0.1) supports skipped exon events only. alternative splicing, rna-seq, alternative splicing event, transcript, annotation, splicing regulation is listed by: OMICtools
is related to: Cufflinks
is related to: Scripture
has parent organization: Indiana University; Indiana; USA
PMID:23281921 Free, Freely available OMICS_01941 SCR_001846 Alt Event Finder: A tool for extracting alternative splicing events from RNA-seq data 2026-02-07 02:05:37 0
ExpressionPlot
 
Resource Report
Resource Website
1+ mentions
ExpressionPlot (RRID:SCR_001904) expressionplot software resource Software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, and a web-based front end, which offers a biologically centered interface to browse, visualize, and compare different data sets. analysis, rna-seq, microarray, gene expression, affymetrix, prototype is listed by: OMICtools PMID:21797991 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01939 SCR_001904 2026-02-07 02:05:37 9
S-MART
 
Resource Report
Resource Website
10+ mentions
S-MART (RRID:SCR_001908) S-MART software resource Software toolbox that manages your RNA-Seq and ChIP-Seq data and also produces many different plots to visualize your data. It performs several tasks that are usually required during the analysis of mapped RNA-Seq and ChIP-Seq reads, including data selection and data visualization. It includes the selection (or the exclusion) of the data that overlaps with a reference set, clustering and comparative analysis. It also provides many ways to visualize data: size of the reads, density on the genome, distance with respect to a reference set, and the correlation of two data sets (with cloud plots). A computer science background is not required to run it through a graphical interface and it can be run on any personal computer, yielding results within an hour for most queries. high throughput sequencing, rna-seq, chip-seq, python, linux, ms windows, mac, short-read, selection, visualization, bio.tools, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:21998740 Free, Available for download, Freely available OMICS_01937, biotools:mapperanalyzer, biotools:s-mart https://bio.tools/s-mart
https://bio.tools/mapperanalyzer
SCR_001908 2026-02-07 02:05:37 23
THetA
 
Resource Report
Resource Website
100+ mentions
THetA (RRID:SCR_001860) software resource An algorithm that estimates the tumor purity and clonal / subclonal copy number aberrations directly from high-throughput DNA sequencing data. standalone software is listed by: OMICtools
has parent organization: Brown University; Rhode Island; USA
PMID:23895164 Free, Available for download, Freely available OMICS_03562 http://compbio.cs.brown.edu/projects/theta/ SCR_001860 THetA: Tumor Heterogeneity Analysis, Tumor Heterogeneity Analysis, Tumor Heterogeneity Analysis (THetA) 2026-02-07 02:05:45 203
SamSPECTRAL
 
Resource Report
Resource Website
1+ mentions
SamSPECTRAL (RRID:SCR_001858) software resource Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample. software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Cancer, HIV PMID:20667133 Free, Available for download, Freely available OMICS_05638, biotools:samspectral https://bio.tools/samspectral SCR_001858 SamSPECTRAL - Identifies cell population in flow cytometry data 2026-02-07 02:05:37 4
RchyOptimyx
 
Resource Report
Resource Website
1+ mentions
RchyOptimyx (RRID:SCR_001889) software resource Software that constructs a hierarchy of cells using flow cytometry for maximization of an external variable (e.g., a clinical outcome or a cytokine response). software package, mac os x, unix/linux, windows, r, flow cytometry is listed by: OMICtools
has parent organization: Bioconductor
PMID:23044634 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05637 SCR_001889 RchyOptimyx - Optimyzed Cellular Hierarchies for Flow Cytometry, RchyOptimyx: Optimyzed Cellular Hierarchies for Flow Cytometry 2026-02-07 02:05:46 3
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-02-07 02:05:43 6
PoissonSeq
 
Resource Report
Resource Website
10+ mentions
PoissonSeq (RRID:SCR_001784) PoissonSeq software resource Software package that implements a method for normalization, testing, and false discovery rate estimation for RNA-sequencing data. normalization, testing, false discovery rate, rna-seq is listed by: OMICtools
has parent organization: Stanford University; Stanford; California
PMID:22003245 Free, Available for download, Freely available OMICS_01950 http://cran.r-project.org/web/packages/PoissonSeq/index.html SCR_001784 PoissonSeq: Significance analysis of sequencing data based on a Poisson log linear model 2026-02-07 02:05:35 32
miRprimer
 
Resource Report
Resource Website
1+ mentions
miRprimer (RRID:SCR_000480) miRprimer software resource Software tool for automatic design of primers for PCR amplification of microRNAs using the method miR-specific RT-qPCR (Balcells, I., Cirera, S., and Busk, P.K. (2011). Specific and sensitive quantitative RT-PCR of miRNAs with DNA primers. BMC Biotechnol. 11, 70). ruby, primer, microrna, rt-qpcr, ms windows, pcr amplification is listed by: OMICtools
has parent organization: SourceForge
PMID:24472427 Free, Available for download, Freely available OMICS_02311 SCR_000480 miRprimer - Automatic design of primers for miR-specific RT-qPCR 2026-02-07 02:05:23 3
pyQPCR
 
Resource Report
Resource Website
pyQPCR (RRID:SCR_000471) pyQPCR software resource A GUI application written in python that deals with quantitative PCR (QPCR) raw data. Using quantification cycle values extracted from QPCR instruments, it uses a proven and universally applicable model to give finalized quantification resu quantitative pcr, python, qt is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_02326 SCR_000471 2026-02-07 02:05:20 0

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