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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Polysolver
 
Resource Report
Resource Website
10+ mentions
Polysolver (RRID:SCR_022278) data analysis software, software resource, data processing software, software application Software tool for HLA typing based on whole exome sequencing data and infers alleles for three major MHC class I genes. Enables accurate inference of germline alleles of class I HLA-A, B and C genes and subsequent detection of mutations in these genes using inferred alleles as reference. HLA typing, whole exome sequencing data, accurate inference of germline alleles, high precision HLA-typing, alleles of class I HLA-A, B and C genes, detection of mutations, inferred alleles has parent organization: Broad Institute Blavatnik Family Foundation ;
NHLBI 1RO1HL103532;
NCI 1R01CA155010;
AACR
PMID:26372948 Free, Available for download, Freely available SCR_022278 POLYmorphic loci reSOLVER, POLYSOLVER 2026-02-14 02:04:42 30
SigCom LINCS
 
Resource Report
Resource Website
1+ mentions
SigCom LINCS (RRID:SCR_022275) data access protocol, software resource, web service Web server that serves over million gene expression signatures processed, analyzed, and visualized from LINCS, GTEx, and GEO. Data and metadata search engine for gene expression signatures. FAIR data, data and metadata search engine, gene expression signatures, gene expression signature processed, analyzed, and visualized, LINCS, GTEx, GEO, gene expression signatures, NHLBI U54HL127624;
NIDDK R01DK131525;
NIH Office of the Director OT2OD030160
PMID:35524556 Free, Freely available https://github.com/MaayanLab/sigcom-lincs SCR_022275 SigCom Library of Integrated Network-based Cellular Signatures 2026-02-14 02:04:38 7
sei
 
Resource Report
Resource Website
1+ mentions
sei (RRID:SCR_022571) data access protocol, software resource, web service Web server for systematically predicting sequence regulatory activities and applying sequence information to human genetics data. Provides global map from any sequence to regulatory activities, as represented by sequence classes, and each sequence class integrates predictions for chromatin profiles like transcription factor, histone marks, and chromatin accessibility profiles across wide range of cell types. systematically predicting sequence regulatory activities, applying sequence information, human genetics data, sequence class predictions National Science Foundation Graduate Research Fellowship Program ;
NHGRI R01HG005998;
NHLBI U54HL117798;
NIGMS R01GM071966
PMID:35817977 Free, Available for download, Freely available https://hb.flatironinstitute.org/sei SCR_022571 2026-02-14 02:05:02 6
Appyters
 
Resource Report
Resource Website
1+ mentions
Appyters (RRID:SCR_021245) software resource, web application Collection of web-based software applications that enable users to execute bioinformatics workflows without coding. Turns Jupyter notebooks into fully functional standalone web-based bioinformatics applications. Each Appyter application introduces data entry form for uploading or fetching data, as well as for selecting options for various settings. Once user presses Submit, Appyter is executed in cloud and user is presented with Jupyter Notebook report that contain results. Report includes markdown text, interactive and static figures, and source code. Appyter users can share the link to the output report, as well as download the fully executable notebook for execution on other platforms. Jupyter Notebooks, data-driven web apps collection, Jupyter Notebook results report is used by: Hypothesis Center
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
NCI U24 CA224260;
NHLBI U54 HL127624;
NIH Office of the Director OT2 OD030160
DOI:10.1016/j.patter.2021.100213 Free, Available for download, Freely available https://github.com/MaayanLab/appyter
https://github.com/MaayanLab/appyter-catalog
SCR_021245 2026-02-14 02:04:12 9
TopDom
 
Resource Report
Resource Website
10+ mentions
TopDom (RRID:SCR_016964) TOPDOM data processing software, data analysis software, software toolkit, software application, software resource Software tool to identify Topological Domains, which are basic builiding blocks of genome structure. Detects topological domains in a linear time., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. identify, topological, domain, genome, structure, linear, time, data, analysis has parent organization: University of Southern California; Los Angeles; USA
works with: CCTOP
NHLBI U01 HL108634;
NIDDK U54 DK107981;
NSF CAREER 0747475;
NSF CAREER 1150287;
Arnold and Mabel Beckman foundation ;
Pew Charitable Trusts
PMID:26704975 THIS RESOURCE IS NO LONGER IN SERVICE SCR_016964 TOPological DOMains, Topological Domains, TopDom_v0.0.2, TopDom_v0.0.1 2026-02-14 02:03:21 10
exRNA Atlas
 
Resource Report
Resource Website
10+ mentions
exRNA Atlas (RRID:SCR_017221) ontology, data repository, storage service resource, application programming interface, data analysis service, expression atlas, portal, analysis service resource, consortium, data or information resource, production service resource, organization portal, service resource, controlled vocabulary, atlas, data access protocol, software resource, database Software tool as data and metadata repository of Extracellular RNA Communication Consortium. Atlas includes small RNA sequencing and qPCR derived exRNA profiles from human and mouse biofluids. All RNAseq datasets are processed using version 4 of exceRpt small RNAseq pipeline. Atlas accepts submissions for RNAseq or qPCR data. Differential, expression, RNA, sequencing, qPCR, data, visualization, extracellular, exRNA, atlas, repository, dataset is recommended by: National Library of Medicine
has parent organization: Baylor College of Medicine; Houston; Texas
has parent organization: exRNA
gastric cancer, colon carcinoma, colorectal cancer, prostate carcinoma, pancreatic carcinoma, multiple sclerosis, glioblastoma multiforme, ulcerative colitis, Alzheimer's disease, ischemic stroke, intraparenchymal hemorrhage of brain, asthma, cardiovascular disorder, myocardial infarction, lupus, nephrotic syndrome, transplanted kidney present, liver disease, transplanted liver present, pre-eclampsia, Parkinson disease, intraventricular brain hemorrhage, subarachnoid hemorrhage NIDA U54 DA036134;
NCI R01 CA163849;
NIGMS R25 GM056929;
NCATS UH3 TR000906;
NCI U19 CA179512;
NIDDK P30 DK63720;
NHLBI K23 HL127099;
NHLBI R01 HL136685;
NIA R01 AG059729;
NCATS UH3 TR000943;
NCI R35 CA209904;
NCI CA217685;
NHLBI R01 HL122547;
American Cancer Society ResearchProfessor Award ;
Frank McGraw Memorial Chair in CancerResearch
PMID:30951672 Restricted SCR_017221 2026-02-14 02:03:10 24
star-for-criu
 
Resource Report
Resource Website
1+ mentions
star-for-criu (RRID:SCR_016294) data processing software, alignment software, software application, software resource, image analysis software Software as an Hot Start software container for STAR alignment using CRIU (Checkpoint Restore in Userspace) tool to freeze the running container. Can be deployed to align RNA sequencing data. Used in the processing of biomedical big data for better reproducibility and reliability. hot, start, container, star, aligner, sequencing, data, processing, biomedical, cloud, reproducibility, RNA, analysis, computing, environment is related to: Systems Transcriptional Activity Reconstruction NHLBI U54 HL127624;
AMEDD Advanced Medical Technology Initiative ;
NIGMS R01 GM126019
Free, Freely available, Available for download https://github.com/paizhang/Hotstarting-For-STAR-Alignment SCR_016294 2026-02-14 02:03:14 1
Sleep Heart Health Study
 
Resource Report
Resource Website
50+ mentions
Sleep Heart Health Study (RRID:SCR_016559) SHHS disease-related portal, data or information resource, portal, topical portal Portal for a multi-cohort study focused on sleep-disordered breathing and cardiovascular outcomes implemented by the National Heart Lung and Blood Institute. Recorded signals are: EEG, ECG, EOG, SaO2, HR, EOG, EMG, respiratory inductance plethysmography, respiration (thermistor), position, light. dataset, analysis, sleep, apnea, breathing, disorder, cardiovascular, disease, EEG, ECG, respiration, PSG is listed by: National Sleep Research Resource (NSRR) sleep disorder, sleep apnea, cardiovascular disease NHLBI U01 HL53916;
NHLBI U01 HL53931;
NHLBI U01 HL53934;
NHLBI U01 HL53937;
NHLBI U01 HL64360;
NHLBI U01 HL53938;
NHLBI U01 HL53941
PMID:9493915 Free, Freely available, Registration required for membership SCR_016559 Sleep Heart Health Study 2026-02-14 02:03:14 76
SINCERA Pipeline
 
Resource Report
Resource Website
1+ mentions
SINCERA Pipeline (RRID:SCR_016563) SINCERA data processing software, data analysis software, data analytics software, software application, software resource Software tool implemented in R S4 as an analytic pipeline for processing single-cell RNA-seq data from a whole organ or sorted cells. Used for Single Cell RNA-Seq profiling analysis. single, cell, RNA seq, data, sorted, whole, organ, profiling, analysis NHLBI U01 HL110964;
NHLBI U01 HL122642;
NHLBI R01 HL105433
PMID:26600239 Free, Available for download, Freely available https://research.cchmc.org/pbge/sincera.html SCR_016563 SINCERA, SINgle CEll RNA seq profiling Analysis 2026-02-14 02:03:14 5
Drug Gene Budger
 
Resource Report
Resource Website
Drug Gene Budger (RRID:SCR_016489) DGB data access protocol, software resource, web service, service resource Web based application to assist researchers with identifying drugs and small molecules that are predicted to maximally influence expression of mammalian gene of interest. Used to identify drugs and small molecules to regulate expression of target genes for research purpose only. Application for ranking drugs to modulate specific gene based on transcriptomic signatures. identify, drug, small, molecule, predict, influence, expression, mammalian, gene, regulate, target is related to: LINCS Project
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
works with: CMAP
works with: Gene Expression Omnibus (GEO)
BD2K-LINCS Data Coordination and Integration Center Mount Sinai Knowledge Management Center for IDG ;
NHLBI U54 HL127624;
NCI U24 CA224260
PMID:30169739 Restricted SCR_016489 Drug Gene Budger 2026-02-14 02:03:05 0
Apnea, Bariatric surgery, and CPAP study
 
Resource Report
Resource Website
Apnea, Bariatric surgery, and CPAP study (RRID:SCR_016575) ABC study disease-related portal, data or information resource, portal, topical portal Portal for randomized controlled trial to compare effectiveness of bariatric surgery versus continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea. Signals included in the polysomnography (PSG) montage are EEG, EMG, EOG, ECG, SpO2, airflow, CPAP pressure, CPAP flow, plethysmography, position, pulse, light, respiratory effort, snore. dataset, bariatric, surgery, continuous, positive, airway, pressure, therapy, sleep, apnea, obesity II is listed by: National Sleep Research Resource (NSRR) class II obesity, obstructive sleep apnea NHLBI R01 HL106410;
NHLBI K24 HL127307
DOI:10.1164/rccm.201708-1637LE Free, Available for public download, Registration required SCR_016575 and Cpap study, Bariatric surgery, Apnea 2026-02-14 02:03:06 0
Best Apnea Interventions for Research (BestAIR) sleep study
 
Resource Report
Resource Website
1+ mentions
Best Apnea Interventions for Research (BestAIR) sleep study (RRID:SCR_016583) BestAIR disease-related portal, data or information resource, portal, topical portal Portal for sleep study to address challenges in conducting future large-scale trials of sleep apnea treatment. Includes data from sleep apnea patients with cardiovascular disease or risk factors. Signals included in the polysomnography (PSG) montage are ECG, SpO2, airflow, nasal pressure, position, pulse, respiratory effort, snore, tidal volume. data, analysis, sleep, apnea, treatment, cardiovascular, disease, risk, factor, polysomnography, ECG, SpO2 is listed by: National Sleep Research Resource (NSRR) sleep apnea, cardiovascular disease ResMed Foundation ;
Philips Respironics ;
NHLBI U34 HL105277
DOI:10.5665/sleep.4266 SCR_016583 bestair, , Best Apnea Interventions for Research, Bestair 2026-02-14 02:03:17 2
Drugmonizome
 
Resource Report
Resource Website
1+ mentions
Drugmonizome (RRID:SCR_024821) data or information resource, database Database with search engine for querying annotated sets of drugs and small molecules for performing drug set enrichment analysis. annotated sets of drugs and small molecules, searching of annotated sets of drugs and small molecules, drugs, small molecules, NCI U24CA224260;
NHLBI U54HL127624;
NIH Office of the Director OT2OD030160
PMID:33787872 Free, Freely available SCR_024821 2026-02-14 02:08:46 1
STARNET
 
Resource Report
Resource Website
1+ mentions
STARNET (RRID:SCR_025238) STARNET data access protocol, software resource, source code, web service Web interactive browser to visualize data and perform gene set enrichment analysis along with gene and SNP lookup. Web interface used to query STARNET datasets and downstream analysis which includes RNAseq from 7 tissues: blood, free internal mammary artery (MAM), atherosclerotic aortic root (AOR), subcutaneous fat (SF), visceral abdominal fat (VAF), skeletal muscle (SKLM), and liver (LIV). Paired SNP genotyping data is included and utilized for tissue expression quantitative trait loci (eQTL), CAD heritability (H2), co-expression networks and gene regulatory networks. cross-tissue co-expression analysis, STARNET multitissue gene expression data, cardiovascular disease patients, NHLBI R01HL125863;
American Heart Association ;
Swedish Research Council ;
Heart Lung Foundation ;
AstraZeneca ;
European Union ;
Federal German Ministries ;
ModulMax ;
NHLBI R01HL130423;
NHLBI R01HL135093;
NHLBI R01HL148167;
New South Wales health ;
NHLBI R01 HL144651;
NHLBI R01 HL147883;
NHLBI PO1 HL28481;
NIDDK R01 DK117850;
NHLBI HL138193
PMID:36276926 Free, Freely available https://github.com/skoplev/starnet SCR_025238 Stockholm-Tartu Atherosclerosis Reverse Networks Engineering Task 2026-02-14 02:08:59 5
MRQy
 
Resource Report
Resource Website
1+ mentions
MRQy (RRID:SCR_025779) data analysis software, software resource, data processing software, software application Software quality assurance and checking tool for quantitative assessment of magnetic resonance imaging and computed tomography data. Used for quality control of MR imaging data. quantitative assessment, magnetic resonance imaging, computed tomography, imaging data, NCI U24CA199374;
NCI R01CA202752;
NCI R01CA208236;
NCI R01CA216579;
NCI R01CA220581;
NCI 1U01CA239055;
NCI 1F31CA216935;
NCI 1U01CA248226;
NHLBI R01HL15127701A1;
NIBIB 1R43EB028736;
NCRR 1C06RR12463
PMID:33176026 Free, Available for download, Freely available SCR_025779 2026-02-14 02:09:06 1
SpaGCN
 
Resource Report
Resource Website
SpaGCN (RRID:SCR_025978) software resource, source code, software application Software graph convolutional network to integrate gene expression and histology to identify spatial domains and spatially variable genes. SpaGCN integrates information from gene. Integrating gene expression and histology, graph convolutional network, identify spatial domains, identify spatially variable genes, NIGMS R01GM125301;
NEI R01EY030192;
NEI R01EY031209;
NHLBI R01HL113147;
NHLBI R01HL150359;
NIA P01AG066597
PMID:34711970 Free, Available for download, Freely available SCR_025978 2026-02-14 02:09:08 0
Collaborative Cohort of Cohorts for COVID-19 Research
 
Resource Report
Resource Website
1+ mentions
Collaborative Cohort of Cohorts for COVID-19 Research (RRID:SCR_026322) C4R portal, data or information resource, disease-related portal, topical portal Portal provides information about nationwide study of more than 50,000 individuals to determine factors that predict disease severity and long-term health impacts of COVID-19. nationwide study, determine factors, predict disease severity, long-term health impacts, COVID-19 COVID-19 NHLBI ;
NINDS ;
NIA
SCR_026322 2026-02-14 02:09:38 1
Conos
 
Resource Report
Resource Website
1+ mentions
Conos (RRID:SCR_026381) software resource, source code, software toolkit Software R package for joint analysis of multiple single-cell RNA-seq datasets. Used to wire together large collections of single-cell RNA-seq datasets, which allows for both identification of recurrent cell clusters and propagation of information between datasets in multi-sample or atlas-scale collections. joint analysis of multiple single-cell RNA-seq datasets, multiple single-cell RNA-seq datasets, identification of recurrent cell clusters, propagation of information between datasets, multi-sample, atlas-scale collections, NHLBI R01HL131768;
NSF ;
Zimin Foundation
DOI:10.1038/s41592-019-0466-z Free, Available for download, Freely available SCR_026381 2026-02-14 02:09:13 6
Metabolic Subphenotype Predictor
 
Resource Report
Resource Website
1+ mentions
Metabolic Subphenotype Predictor (RRID:SCR_027192) software resource, source code Software repository contains code for Inference of T2D metabolic subphenotypes (MuscleIR, Beta-cell Function, Incretin Effect, Hepatic IR), Identification of dominant metabolic subphenotype, Feature extraction from glucose tiemseries, Extraction of reduced representation of glucose tiemseries,Visualization of metabolic phenotypes based on various glucose-related metrics,Concordance between CGM and Venous glucose values from at home and at clinical setting, Classification of metabolic subphenotypes. Inference of T2D metabolic subphenotypes, identification of dominant metabolic subphenotype, extraction from glucose tiemseries, visualization of metabolic phenotypes, classification of metabolic subphenotype, s NIDDK R01 DK110186;
Stanford PHIND award ;
Stanford Diabetes Research Center ;
Wellcome Trust ;
NIDDK U01 DK105535;
NIDDK U01 DK085545;
NIDDK UM1DK126185;
NHLBI 2T32HL09804911
PMID:39715896 Free, Available for download, Freely available SCR_027192 2026-02-14 02:09:56 1
T Cell ExTRECT
 
Resource Report
Resource Website
T Cell ExTRECT (RRID:SCR_027742) software resource, source code, software toolkit Software R package to calculate T cell fractions from WES data from hg19 or hg38 aligned genomes. T-cell, T cell receptor excision circle, WES data, hg19 or hg38 aligned genomes, NHLBI U54HL108460;
NCATS UL1TR000100;
NCI R21CA177519;
NCI P30CA023100;
NCI U01CA196406;
NLM T15LM011271;
NIH Office of the Director DP5OD017937;
NSF
PMID:34497419 Free, Available for download, Freely available SCR_027742 , T cell exome TREC, T cell exome T cell Receptor Excision Circle 2026-02-14 02:09:59 0

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