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http://jsu.eagle-i.net/i/0000012b-d4be-703e-3bf4-a80880000000

Core facility that provides the following services: Computational access service. The Computational Modeling Core is part of the CREST Interdisclipinary Center for Nanotoxicity, aka the Center for Applied Computational Sciences.

Proper citation: JSU Computational Modeling Core Laboratory (RRID:SCR_009891) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a0c0-39f6-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30, 2023. Core facility that provides the following services: Microscopy consultation services, Technical microscopy service, Microscopy training services, Conventional immunofluorescence microscopy service, Confocal microscopy service, Live-cell imaging service, Conventional electron microscopy service, EM immunogold labeling service, Tissue sectioning service, Tissue fixation, Computer based image analysis and quantification.

Proper citation: MGH PMB Microscopy Core (RRID:SCR_009928) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012e-5936-2dc1-0e5d-6ffe80000000

Core facility that provides the following services: Fragment (microsatellite) analysis service, Enumeration of polymorphisms (SNPs), DNA sequencing.

The DNA Sequencing Lab is the longest-established lab in the Gene Profiling Core, providing DNA sequence analysis to investigators involved in research utilizing molecular biology techniques. The lab uses capillary electrophoresis sequencing technology and is built around the ABI 3130xl Gene Analyzer (16-capillary) and associated software for DNA sequence analysis.

Proper citation: MSM DNA Sequencing Laboratory (RRID:SCR_009929) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-edef-166a-b2b9-4d8780000000

Core facility that provides the following services: Magnetic Resonance Spectroscopy Service, Magnetic Resonance Imaging Service.

The Musculoskeletal Imaging Research Core (MIRC) offers specialized imaging techniques including quantitative computed tomography (QCT), magnetic resonance (MR) spectroscopy of muscle and high-resolution soft tissue MR imaging. QCT is a technique widely employed for studies evaluating body composition and bone mineral density. MR spectroscopy is a technique that allows non-invasive quantification of metabolites in human tissues.

Proper citation: MGH Musculoskeletal Imaging Research Core (RRID:SCR_009926) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-2508-4b59-43fb-601a80000000

The core laboratory facility has the necessary equipment to provide each study with the initial specimen processing and handling required for shipping to a reference laboratory and for storage and maintenance at a sample repository. Laboratory procedures provided by the core laboratory are intended for research use only,and not for diagnostic; it may provide other specialized services for specific protocols on a case by case basis.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Core Laboratory (RRID:SCR_009922) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5961-f9b9-55da-381e80000000

Core facility that provides the following services: Flow cytometric analysis and cell sorting. The cell sorting and analysis lab provides access to the most sophisticated flow cytometers presently available. The core is able to analyze and physically separate cells based upon features detectable with fluorescently labeled monoclonal antibodies. This facilities has two locations: the Simches site and the Charlestown Navy Yard (CNY) site.

Proper citation: MGH Flow Cytometry Core Facility (RRID:SCR_009887) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-b800-0461-d807-77a880000000

Core facility that provides the following services: Fresh hepatocytes in suspension, Plated hepatocytes, Cryopreserved hepatocytes, Custom hepatocyte isolations, Decellularized whole rat livers. The mission of the Cell Resource Core (CRC) is to provide high quality primary cells and tissues to researchers reliably and affordably. Leveraging a new MGH technology that significantly increases the viable yield of high quality hepatocytes from human and animal donor livers, we are initially offering hepatocytes to the research community.

Proper citation: MGH Cell Tissue and Organ Resource Core (RRID:SCR_009920) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012a-2505-c6a1-b307-36d480000000

Core facility that provides the following services: Statistical design and analysis. Applied statistical methodologies and data analysis techniques are critical under-girding factors in research and knowledge advancement. Appropriate experimental design lays foundation of sound research plans; sample size determines the power of significance and efficient utilization of scarce resources; and adequate data analysis generate results that are valid and true representative of the population in question. The Biostatistical Support Unit (BSU) provides statistical services and research support to RCMI investigators, other faculty, as well as to graduate and undergraduate students.(http://www.jsums.edu/cset/rcmi/bsu.htm)

Proper citation: JSU BSU-RCMI Biostatistics Core Laboratory (RRID:SCR_009888) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-9652-3f24-55da-381e80000000

Core facility that provides the following services: Double- and triple-labeling experiments, Acquisition of high-resolution images: 2048 x 2048 pixels, Single molecule visualization, allowing dynamic observation and functional analyses of both in vivo and living cells, Total internal reflection fluorescence experiments (TIRF).

This Core consists of a Zeiss LSM 5 Pascal laser confocal microscope with a Zeiss RGB vario laser module and Nikon C1 Confocal/TIRF System with 3 PMT. A Zeiss Axiovert 200 fully motorized light microscope is available with fluorescence, bright-field, phase-contrast and Nomarski (DIC) capabilities. Image acquisition and analyses are performed using Zeiss LSM 5 Pascal Confocal Microscopy Software (Release 3.2) on 2 workstations. Zeiss Physiology software is available also. Live cell imaging is available using a Zeiss temperature controller with custom chamber and heating stage. The Nikon C1 Confocal/TIRF System fully motorized Nikon Eclipse Ti microscope is available with fluorescence, bright-field and TIRF capabilities. Imaging acquisition and analyses are performed using EZ-C1 and NIC-Elements Software.

Proper citation: MGH Confocal Microscope Core (RRID:SCR_009921) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bc-22cd-3984-bcfb80000000

Core facility that provides the following services: Animal husbandry service. The Animal Care Facility (ACF) is one of the essential units of support and service to the biomedical research at Jackson State University. Its long term goal is to develop a state-of-the-art infrastructure as well as to provide technical and logistic support to RCMI investigators and other JSU faculty and students to conduct a high quality of animal research, in compliance with the guidelines and policies set for by accrediting and regulatory agencies, especially as they relate to IACUC protocol development, animal husbandry, food and water supply, veterinary care, quarantine and euthanasia, sanitation procedures, environmental monitoring, and record keeping. ACF provides accommodation for long-term storage of animals and maintains them in accordance with and in compliance with the PHS Policy on the Humane Care and Use of Laboratory Animals and the Animal Welfare Act, as described in the 2002 Guide for the Care and Use of Laboratory Animals.

Proper citation: JSU Animal Core Facility (RRID:SCR_009886) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a183-b053-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core provides the following services: Trypsinization service. Core provides a full range of services to the Joslin research community spanning from consulting on proteomic experimental design to data acquisition and analysis. The core operates a high throughput nano liquid chromatography, nanospray ionization, LTQ 2D ion trap tandem mass spectrometer system. This system is used for two routine proteomic services, including Targeted Protein Analysis and Protein Inventory. Targeted Protein Analysis is used to identify and provide in depth characterization, including phosphorylation site mapping, of proteins isolate by SDS-PAGE. Protein Inventory is used to catalogue the protein composition in a sample separated by 1D SDS-PAGE. This service provides information on protein identification, molecular weight (gel mobility), and spectral/peptide counts, a semi-quantitative measure of protein abundance. In addition, the Core works with investigators on specialized analyses involving tandem mass spectrometry, including specialized enzymatic digests (peptide preparation), selective reaction monitoring (SRM), and targeted peptide detection. The Proteomic Core provides in house database resources and analysis tools and also coordinates with Joslin's Bioinformatics Core to provide further assistance with data organization and interpretation. The Core hosts seminars on proteomic topics and provides instruction on practical and theoretical aspects of mass spectrometry-based proteomics.

Proper citation: Joslin Diabets Center Proteomics Core Facility (RRID:SCR_009883) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-97ab-90a0-55da-381e80000000

Core facility that provides the following services: Custom mutation detection and DNA sequencing services, Custom genotyping service.

This resource provides custom genotyping (microsatellite, SNP, other) in human and mouse, mutation detection/DNA sequencing, dosage analysis and related services to further the CHGR mission of promoting the use of genetic strategies in basic and clinical research.

Proper citation: MGH CHGR Genotyping Resource (RRID:SCR_009919) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-ee0d-d869-b2b9-4d8780000000

Core facility that provides the following services: DNA sequencing service, High volume DNA sequencing, Plasmid verification and primer walking service, PCR purification service, Microsatellite analysis.

The DNA Sequencing Core at the Massachusetts General Hospital functions both as a small-scale sequencing facility and a high-throughput center for large-scale sequencing projects.

Proper citation: MGH CCIB DNA Sequencing Core (RRID:SCR_009915) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000135-7dbd-9133-9658-54ab80000000

The Molecular Biology Core Facility at Meharry Medical College is a multi-functional facility that provides to faculty, students, and staff of the college the primary service of DNA sequencing but also provides access to shared equipment housed in a centralized location and facilitates convenient and rapid access to frequently used molecular biological reagents.RRRRR RRRRR The Molecular Biology Core houses a number of shared items of research instrumentation. The core also maintains an Invitrogen Supply Center that stocks many routinely used reagents for molecular biological research. RRRRR RRRRR The major service activities of the Molecular Biology Core are to provide training and technical assistance with the use of shared equipment housed in the core and provide convenient access to molecular biological reagents. Training in the proper use of equipment is provided by the Laboratory Coordinator and also as needed by vendor technical personnel. The core maintains in-house freezers and supply cabinets stocked with many commonly used molecular biological reagents from Invitrogen. In-house reagents are ordered online from Invitrogen and picked up from stocks housed in the core. Invitrogen items not stocked in the core can be ordered online without shipping charges.

Proper citation: Meharry Molecular Biology Core Facility (RRID:SCR_009953) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013d-1e69-de33-6d01-360380000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The mission of the Investigator Support and Integration Services (ISIS) program is to facilitate clinical and translational research at OHSU and the Portland VA Medical Center. ISIS works with these institutional partners to streamline study start-up and management processes and related administrative and compliance processes and provide pre-award and regulatory services to investigators. ISIS administers the Human Subjects Protection Program of the Clinical and Translational Research Center (CTRC) to maximize the protection of human subjects involved in OCTRI projects. The OHSU Clinical Trials Office, a unit within ISIS, provides study start-up services and negotiation of contracts for OHSU industry-sponsored clinical trials.

Proper citation: OHSU Investigator Support and Integration Services (RRID:SCR_009951) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000134-a542-2d86-9658-54ab80000000

Core facility that provides the following services: Immunohistochemistry service, Routine histology service, Tissue procurement service. The Human Tissue & Pathology Core provides tissue collection and storage services and access to human tissue, histology services, and specialized equipment. The Core collects human tissues prospectively from routine surgical resections and autopsies for use in basic, translational, and clinical research. Only remnant tissue samples not needed for diagnostic purposes are collected. Tissues are available fresh, snap frozen, or in a variety of fixatives, and normal, neoplastic, and other diseased tissues are available. Histology services include paraffin embedding, paraffin sectioning, automated Hematoxylin and Eosin staining, frozen sectioning, special stains, immunohistochemistry and other specialized processing and sectioning services.

Proper citation: Meharry Human Tissue Acquistion and Pathology Core (RRID:SCR_009952) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000135-2fb3-d3f3-9658-54ab80000000

Core facility that provides the following services: Flow cytometry service. The FACS Core provides a state-of-the-art multi parameter flow cytometry and biosafty level 3 facility on the Meharry Medical College campus. The facility performs flow cytometry analysis, provides expertise in implementing and developing technologies for cell analysis, and provides training to investigators in the use of the instrumentation and in the interpretation of data analysis

Proper citation: Meharry Flow Cytometry and BSL3 Core (RRID:SCR_009950) Copy   

•   Source: SciCrunch Registry

http://montana.eagle-i.net/i/0000012b-00bd-ecd1-df3b-3fdc80000000

Core facility that provides the following services: Macromolecular crystal structure analysis, Macromolecular crystallization.

The Montana State University Macromolecular Crystallography Facility provides modern facilities for macromolecular crystallization and structural analysis.

Proper citation: MSU X-ray Crystallography Core Laboratory (RRID:SCR_009947) Copy   

•   Source: SciCrunch Registry

http://montana.eagle-i.net/i/0000012b-00be-96b8-df3b-3fdc80000000

Core facility that provides the following services: MicrOTOF (access), GCMS (access), MALDI (access), XCT ion trap (access), MicrOTOF high resolution (facility run), MicrOTOF low res (facility run), MALDI (facility run), GCMS (facility run), HPLC-micrOTOF (facility run), 2-D gel (access), 2-D gel (facility run).

The mission of the Mass Spectrometry and Proteomics Facility is to seed mass spectrometry and proteomics technology to research labs at Montana State University and affiliated programs.

Proper citation: MSU Proteomics Core Laboratory (RRID:SCR_009944) Copy   

•   Source: SciCrunch Registry

http://montana.eagle-i.net/i/0000012a-2501-c6be-f94c-e32480000000

Core facility that provides the following services: NMR-based metabolite profiling, MS-based metabolite profiling service.

Lab performs services related to Metabolomics and Metabolite Profiling.

Proper citation: MSU Metabolomics Core Facility (RRID:SCR_009942) Copy   

•   Source: SciCrunch Registry