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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://pfind.ict.ac.cn/software/pBuild/index.html
A software tool that can compare several search engines' results and combine them together.
Proper citation: pBuild (RRID:SCR_002929) Copy
http://cran.r-project.org/src/contrib/Archive/aCGH.Spline/
An R package for array comparative genomic hybridization (aCGH) dye bias normalization.
Proper citation: aCGH.Spline (RRID:SCR_002927) Copy
https://github.com/GiBacci/StreamingTrim/
A DNA reads trimming software, written in Java, with which researchers are able to analyse the quality of DNA sequences in fastq files and to search for low-quality zones in a very conservative way.
Proper citation: StreamingTrim (RRID:SCR_002922) Copy
http://pfind.ict.ac.cn/software/pLabel/index.html
Mass spectral peak labeling software developed for proteomics research., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: pLabel (RRID:SCR_002923) Copy
https://github.com/itojal/hot_scan
A free software to detect genomic regions unusually rich in translocation breakpoints. More generally, it may be used to detect a region that is unusually rich in a given character of a binary sequence.
Proper citation: hot scan (RRID:SCR_002840) Copy
A fast and versatile Open Source docking software program that can be used to dock small molecules against proteins and nucleic acids.
Proper citation: rDock (RRID:SCR_002838) Copy
http://www.bioconductor.org/packages/release/bioc/html/Basic4Cseq.html
An R/Bioconductor package for basic filtering, analysis and subsequent near-cis visualization of 4C-seq data. Virtual fragment libraries can be created for any BSGenome package, and filter functions for both reads and fragments and basic quality controls are included. Fragment data in the vicinity of the experiment's viewpoint can be visualized as a coverage plot based on a running median approach and a multi-scale contact profile.
Proper citation: Basic4Cseq (RRID:SCR_002836) Copy
https://github.com/PacificBiosciences/SMRT-Analysis/
Open-source bioinformatics software suite for analyzing single molecule, real-time DNA sequencing data. Users can choose from a variety of analysis protocols that utilize PacBio and third-party tools. Analysis protocols include de novo genome assembly, cDNA mapping, DNA base-modification detection, and long-amplicon analysis to determine phased consensus sequences.
Proper citation: SMRT-Analysis (RRID:SCR_002942) Copy
http://www.bioconductor.org/packages/release/bioc/html/mzR.html
Software that provides a unified API to the common file formats and parsers available for mass spectrometry data. It comes with a wrapper for the ISB random access parser for mass spectrometry mzXML, mzData and mzML files.
Proper citation: mzR (RRID:SCR_002856) Copy
http://www.bioconductor.org/packages/release/bioc/html/BiGGR.html
Software package that provides an interface to simulate metabolic reconstruction from the BiGG database and other metabolic reconstruction databases. The package facilitates flux balance analysis (FBA) and the sampling of feasible flux distributions. Metabolic networks and estimated fluxes can be visualized with hypergraphs.
Proper citation: BiGGR (RRID:SCR_002854) Copy
http://www.bioconductor.org/packages/release/bioc/html/PAPi.html
An R package for predicting the activity of metabolic pathways based solely on a metabolomics data set containing a list of metabolites identified and their respective abundances in different biological samples. PAPi generates hypothesis that improves the final biological interpretation.
Proper citation: PAPi (RRID:SCR_002857) Copy
http://www.ebi.ac.uk/arrayexpress/
International functional genomics data collection generated from microarray or next-generation sequencing (NGS) platforms. Repository of functional genomics data supporting publications. Provides genes expression data for reuse to the research community where they can be queried and downloaded. Integrated with the Gene Expression Atlas and the sequence databases at the European Bioinformatics Institute. Contains a subset of curated and re-annotated Archive data which can be queried for individual gene expression under different biological conditions across experiments. Data collected to MIAME and MINSEQE standards. Data are submitted by users or are imported directly from the NCBI Gene Expression Omnibus.
Proper citation: ArrayExpress (RRID:SCR_002964) Copy
http://cran.r-project.org/web/packages/CNVassoc/
Software package that carries out association analysis of common copy number variants in population-based studies. It includes functions for analysing association under a series of study designs (case-control, cohort, etc), using several dependent variables (class status, censored data, counts) as response, adjusting for covariates and considering various inheritance models. It also includes functions for inferring copy number (CNV genotype calling). Various classes and methods for generic functions (print, summary, plot, anova, ... ) have been created to facilitate the analysis.
Proper citation: CNVassoc (RRID:SCR_002901) Copy
http://chiulab.ucsf.edu/surpi/
Software providing a computational pipeline for pathogen identification from complex metagenomic next-generation sequencing (NGS) data generated from clinical samples.
Proper citation: SURPI (RRID:SCR_003071) Copy
Database that provides a resource to store DNA methylation data and to make these data readily available to the public. Future development of the database will focus on environmental effects on DNA methylation. No restriction applies on the type of data, i.e. as well as global estimations (e.g. HPLC) as data from high resolution analysis (i.e. sequencing) can be stored. As much background information as possible should be provided by the users. This includes the origin of the sample, phenotype, expression of the related gene, etc..
Proper citation: MethDB (RRID:SCR_003108) Copy
http://sourceforge.net/projects/fas-dpd/
Software program to design degenerate primers for PCR.
Proper citation: FAS-DPD (RRID:SCR_003068) Copy
A software package for the analysis of nucleotide polymorphism from aligned DNA sequence data. DnaSP can estimate several measures of DNA sequence variation within and between populations (in noncoding, synonymous or nonsynonymous sites, or in various sorts of codon positions), as well as linkage disequilibrium, recombination, gene flow and gene conversion parameters. DnaSP can also carry out several tests of neutrality: Hudson, Kreitman and Aguad (1987), Tajima (1989), McDonald and Kreitman (1991), Fu and Li (1993), and Fu (1997) tests. Additionally, DnaSP can estimate the confidence intervals of some test-statistics by the coalescent. The results of the analyses are displayed on tabular and graphic form.
Proper citation: DnaSP (RRID:SCR_003067) Copy
http://compbio.berkeley.edu/proj/juncbase/Home.html
Software used to identify and classify alternative splicing events from RNA-Seq data. JuncBASE also uses read counts to quantify the relative expression of each isoform and identifies splice events that are significantly differentially expressed across two or more samples.
Proper citation: JuncBASE (RRID:SCR_003103) Copy
http://pfind.ict.ac.cn/software/pFind/index.html
A search engine system for automated peptide and protein identification from tandem mass spectra.
Proper citation: pFind (RRID:SCR_003011) Copy
http://igenomed.stanford.edu/~junhee/JETTA/rnaseq.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented July 6, 2017. Software to detect alternatively spliced exons between two conditions, for example, between two groups of treated and untreated patients in a typical clinical study.
Proper citation: JETTA (RRID:SCR_003091) Copy
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