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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SNP HITLINK
 
Resource Report
Resource Website
SNP HITLINK (RRID:SCR_013340) SNP HITLINK software application, software resource Software program providing a useful pipeline to directly connect SNP data and linkage analysis program. SNP HiTLink currently supports the data from SNP chips provided by Affymetrix (Mapping 100k/500k array set, Genome-Wide Human SNP array 5.0/6.0) and Illumina (recently supported), carrying out typical linkage analysis programs of MLINK (FASTLINK/ LINKAGE package), Superlink, Merlin and Allegro. (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154644, biotools:snp_hitlink https://bio.tools/snp_hitlink SCR_013340 SNP HIgh-Throughput LINKage analysis system 2026-02-15 09:20:43 0
SGS
 
Resource Report
Resource Website
SGS (RRID:SCR_013460) SGS software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, visualbasic, ms-windows, (95/98/00/nt) is listed by: Genetic Analysis Software nlx_154054 SCR_013460 2026-02-15 09:20:28 0
MCLEEPS
 
Resource Report
Resource Website
MCLEEPS (RRID:SCR_013062) software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, c++, unix, macos is listed by: Genetic Analysis Software nlx_154469 SCR_013062 Monte Carlo Likelihood Estimation of Effective Population Size PANGAEA 2026-02-15 09:20:40 0
AUTOSCAN
 
Resource Report
Resource Website
10+ mentions
AUTOSCAN (RRID:SCR_013510) AUTOSCAN software application, software resource A helper program to automate the tedious process of the creation of input files from genotype data of genome-wide scans (entry from Genetic Analysis Software) gene, genetic, genomic, c and unix-shell (bourne), unix, (solaris/dec-unix) is listed by: Genetic Analysis Software nlx_154235 SCR_013510 2026-02-15 09:20:42 18
PROGENY
 
Resource Report
Resource Website
100+ mentions
PROGENY (RRID:SCR_006647) Progeny software application, software resource, commercial organization, data management software Fully customizable, comprehensive genetic pedigree and clinical data management software including a multi-user relational database with an integrated pedigree drawing component to manage genetic and pedigree data in one database. Manage Pedigrees, Individuals, SNPs, STRs, Samples, Plates, Genotypes and exports to multiple analysis platforms. (entry from Genetic Analysis Software) * LIMS software, providing advanced sample tracking and management (including functionality to generate and record barcodes) and configurable workflows for your specific environment. * Full genotype management gives users the ability to track not only family-based studies, but Whole Genome Association studies containing 1000''s of samples with large arrays. gene, genetic, genomic, c++, active x control, ms-windows, pedigree, clinical, genotype, data management, drawing, family history, questionnaire, sample, lab management, FASEB list is listed by: OMICtools
is listed by: Genetic Analysis Software
nlx_154553, OMICS_00216 SCR_006647 Progeny Software LLC, Progeny Software 2026-02-16 09:46:46 407
LDHEATMAP
 
Resource Report
Resource Website
100+ mentions
LDHEATMAP (RRID:SCR_006312) software application, software resource Software application that plots measures of pairwise linkage disequilibria for SNPs (entry from Genetic Analysis Software) gene, genetic, genomic, r is listed by: Genetic Analysis Software nlx_154424, SCR_009347, nlx_154561 http://stat-db.stat.sfu.ca:8080/statgen/research/LDheatmap SCR_006312 R/LDHEATMAP 2026-02-16 09:46:41 160
HCLUST
 
Resource Report
Resource Website
1000+ mentions
HCLUST (RRID:SCR_009154) HCLUST software application, software resource Software application that is a simple clustering method that can be used to rapidly identify a set of tag SNP's based upon genotype data (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, r, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:h-clust, SCR_009102, nlx_154195, nlx_154331 https://bio.tools/h-clust SCR_009154 R/HCLUST 2026-02-16 09:47:21 1459
SOAP
 
Resource Report
Resource Website
100+ mentions
SOAP (RRID:SCR_000689) SOAP, data processing software, software application, software resource Software package that provides full solution to next generation sequencing data analysis consisting of an alignment tool (SOAPaligner/soap2), a re-sequencing consensus sequence builder (SOAPsnp), an indel finder ( SOAPindel ), a structural variation scanner ( SOAPsv ), a de novo short reads assembler ( SOAPdenovo ), and a GPU-accelerated alignment tool for aligning short reads with a reference sequence. (SOAP3/GPU)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, next generation sequencing, alignment, short read, bio.tools lists: SOAPfusion
lists: SOAPfuse
lists: SOAPnuke
lists: GapCloser
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: BGI; Shenzhen; China
is parent organization of: SOAP3
is parent organization of: SOAPaligner/soap2
PMID:18227114 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154652, biotools:soap https://bio.tools/soap SCR_000689 SOAP: short oligonucleotide alignment program, Short Oligonucleotide Analysis Package 2026-02-16 09:45:19 402
GATK
 
Resource Report
Resource Website
10000+ mentions
GATK (RRID:SCR_001876) GATK software application, data processing software, software toolkit, data analysis software, software library, software resource A software package to analyze next-generation resequencing data. The toolkit offers a wide variety of tools, with a primary focus on variant discovery and genotyping as well as strong emphasis on data quality assurance. Its robust architecture, powerful processing engine and high-performance computing features make it capable of taking on projects of any size. This software library makes writing efficient analysis tools using next-generation sequencing data very easy, and second it's a suite of tools for working with human medical resequencing projects such as 1000 Genomes and The Cancer Genome Atlas. These tools include things like a depth of coverage analyzers, a quality score recalibrator, a SNP/indel caller and a local realigner. (entry from Genetic Analysis Software) gene, genetic, genomic, next-generation resequencing, bio.tools is used by: Halvade Somatic
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SnpEff
has parent organization: Broad Institute
PMID:21478889 Free, Available for download, Freely available nlx_154324, OMICS_00286, biotools:gatk http://www.broadinstitute.org/gsa/wiki/index.php/The_Genome_Analysis_Toolkit
https://bio.tools/gatk
SCR_001876 Genome Analysis ToolKit 2026-02-16 09:45:36 16663
SNAP - SNP Annotation and Proxy Search
 
Resource Report
Resource Website
100+ mentions
SNAP - SNP Annotation and Proxy Search (RRID:SCR_002127) SNAP software application, data analysis service, analysis service resource, software resource, production service resource, service resource A computer program and web-based service for the rapid retrieval of linkage disequilibrium proxy single nucleotide polymorphism (SNP) results given input of one or more query SNPs and based on empirical observations from the International HapMap Project and the 1000 Genomes Project. A series of filters allow users to optionally retrieve results that are limited to specific combinations of genotyping platforms, above specified pairwise r2 thresholds, or up to a maximum distance between query and proxy SNPs. SNAP can also generate linkage disequilibrium plots gene, genetic, genomic, r, oracle, single nucleotide polymorphism, linkage disequilibrium, genotypeing array, physical distance, membership, proxy, plot is listed by: OMICtools
is listed by: Genetic Analysis Software
is related to: International HapMap Project
is related to: 1000 Genomes: A Deep Catalog of Human Genetic Variation
has parent organization: Broad Institute
NHLBI N01-HC-65226 PMID:18974171 Free, Freely Available OMICS_01927, nlx_154638 http://www.broad.mit.edu/mpg/snap/ SCR_002127 SNAP (SNP Annotation and Proxy Search), SNAP 2, SNP Annotation and Proxy Search 2026-02-16 09:45:44 144
VAAST
 
Resource Report
Resource Website
10+ mentions
VAAST (RRID:SCR_002179) VAAST, VAAST 2 software application, data processing software, sequence analysis software, data analysis software, software resource, standalone software A probabilistic search tool for identifying damaged genes and their disease-causing variants in personal genome sequences. VAAST combines elements of phylogenetic conservation, amino acid substitution, and aggregative approaches to variant prioritization into a single unified likelihood-framework that allows users to accurately identify damaged genes and deleterious variants. The software can score both coding (SNV, indel and splice site) and non-coding variants (SNV), evaluating the cumulative impact of both types of variants simultaneously. It can identify rare variants causing rare genetic diseases and can also use both rare and common variants to identify genes responsible for common diseases. sequence analysis software, genetic, variant classifier, amino acid substitution, disease, genome interpretation, variant prioritization, disease gene prioritization, genomic variation, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: Opal Research
has parent organization: Yandell Lab Portal
PMID:23836555
PMID:21700766
Free, Freely available nlx_154686, SciRes_000138, biotools:vaast, OMICS_02134 https://bio.tools/vaast SCR_002179 Variant Annotation Analysis and Search Tool, Variant Annotation Analysis & Search Tool 2026-02-16 09:45:42 30
QGene
 
Resource Report
Resource Website
100+ mentions
QGene (RRID:SCR_003209) QGene software application, data processing software, data analysis software, source code, software resource, simulation software A free, open-source, computationally efficient Java program for comparative analyses of QTL mapping data and population simulation that runs on any computer operating system. (entry from Genetic Analysis Software) It is written with a plug-in architecture for ready extensibility. The software accommodates line-cross mating designs consisting of any arbitrary sequence of selfing, backcrossing, intercrossing and haploid-doubling steps that includes map, population, and trait simulators; and is scriptable. Source code is available on request. gene, genetic, genomic, java, qtl mapping, trait analysis, trait, population, simulation, map, quantitative trait locus, comparison, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Kansas State University; Kansas; USA
NSF DBI 0109879;
USDA-NRI Applied Plant Genomics Program 2004-35317-14867
PMID:18940826 Free, Available for download, Freely available biotools:qgene, nif-0000-31383 https://bio.tools/qgene http://coding.plantpath.ksu.edu/qgene SCR_003209 QGene - Software for QTL data exploration 2026-02-16 09:46:02 126
ARP.GEE
 
Resource Report
Resource Website
1+ mentions
ARP.GEE (RRID:SCR_013134) software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software application that simultaneously estimates a trait-locus position and its genetic effects for affected relative pairs (ARP) by one of two methods. Either allow a different trait-locus effect for each ARP type, or constrain the trait-locus effects according to the marginal effect of a single susceptibility locus. We include a goodness of fit statistic for the constrained model. (entry from Genetic Analysis Software) gene, genetic, genomic, r/s-plus is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154206, nlx_154232, SCR_009108 SCR_013134 R/ARP.GEE 2026-02-16 09:48:25 7
PolyPhen: Polymorphism Phenotyping
 
Resource Report
Resource Website
1000+ mentions
PolyPhen: Polymorphism Phenotyping (RRID:SCR_013189) PolyPhen, PolyPhen-2, POLYPHEN software application, data processing software, data analysis software, software resource, simulation software Software tool which predicts possible impact of amino acid substitution on structure and function of human protein using straightforward physical and comparative considerations. PolyPhen-2 is new development of PolyPhen tool for annotating coding nonsynonymous SNPs. annotate, nonsynonymous, SNP, predict, coding, damaging, effect, missense, mutation, sequence, variant, phenotype, genetic, disease, exon, protein, coding, fraction, genome, bio.tools is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is related to: OMICtools
has parent organization: Harvard University; Cambridge; United States
PMID:20354512
PMID:23315928
SCR_013200, OMICS_00136, nlx_154540, nif-0000-21329, biotools:polyphen, SCR_013238 https://bio.tools/polyphen http://www.bork.embl-heidelberg.de/PolyPhen/ SCR_013189 PolyPhen, POLYPHEN, PolyPhen-2, Polymorphism Phenotyping, Polymorphism Phenotyping v2 2026-02-16 09:48:26 4151
SIFT
 
Resource Report
Resource Website
10000+ mentions
SIFT (RRID:SCR_012813) SIFT web service, data analysis service, analysis service resource, data access protocol, software resource, source code, production service resource, service resource Data analysis service to predict whether an amino acid substitution affects protein function based on sequence homology and the physical properties of amino acids. SIFT can be applied to naturally occurring nonsynonymous polymorphisms and laboratory-induced missense mutations. (entry from Genetic Analysis Software) Web service is also available. gene, genetic, genomic, amino acid, substitution, protein function, coding region, single nucleotide variant, coding indel, deletion, insertion, sequence, protein, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SIFT 4G
has parent organization: Genome Institute of Singapore; Singapore; Singapore
has parent organization: J. Craig Venter Institute
Agency for Science Technology and Research ;
NIGMS GM29009
PMID:19561590
PMID:12824425
PMID:11337480
DOI:10.1038/nprot.2009.86
Non-commercial biotools:sift, OMICS_00137, nlx_154618 http://sift.jcvi.org/
https://bio.tools/sift
https://sources.debian.org/src/sift/
http://sift.bii.a-star.edu.sg/SIFT.html SCR_012813 Sorting Intolerant From Tolerant 2026-02-16 09:48:13 10223
ALLELIX
 
Resource Report
Resource Website
1+ mentions
ALLELIX (RRID:SCR_009115) ALLELIX software application, data analysis service, analysis service resource, software resource, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 23, 2013. Software application / data analysis service where one can enter the alleles of commonly used STR by clicking the mouse. The algorithm calculates the paternity index and the Essen-Moeller probability of kinship for the deficiency- and the trio case. Everybody can use the network-software online after registering. The usage on the internet is free. Academic users can ask me to unlock an option to display the details (formulas/frequencies etc.) and to have an export-funktion to MS Word. The program is in German and (non-professional) English. An expansion to other languages is easy, if somebody helps us with the translation. For those who are interested to have the software running on their own intranet (for database security reasons) an individual agreement can be found. (entry from Genetic Analysis Software) (German version is: http://www.allelix.de) gene, genetic, genomic, c++, java script, ms-windows, (2000 &iis/me & personal webserver) is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154216 SCR_009115 Allelix - Paternity Linkage Analysis Online 2026-02-16 09:47:20 2
CMAP
 
Resource Report
Resource Website
100+ mentions
CMAP (RRID:SCR_009034) CMap software application, data processing software, data analysis software, software resource Web-based tool that allows users to view comparisons of genetic and physical maps. The package also includes tools for curating map data. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, unix, solaris, freebsd, linux, sequence, FASEB list is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SoftCite
has parent organization: Generic Model Organism Database Project
works with: Drug Gene Budger
PMID:19648141 GNU General Public License nlx_153998, OMICS_00933 https://sourceforge.net/projects/gmod/files/cmap/ http://www.gmod.org/cmap/, http://gmod.org/wiki/Cmap SCR_009034 , GMOD Comparative Mapping (CMap) tool, Comparative Mapping tool, genetic and comparative maps 2026-02-16 09:47:20 413
Haploview
 
Resource Report
Resource Website
5000+ mentions
Haploview (RRID:SCR_003076) Haploview data processing software, software application, source code, software resource A Java based software tool designed to simplify and expedite the process of haplotype analysis by providing a common interface to several tasks relating to such analyses. Haploview currently allows users to examine block structures, generate haplotypes in these blocks, run association tests, and save the data in a number of formats. All functionalities are highly customizable. (entry from Genetic Analysis Software) * LD & haplotype block analysis * haplotype population frequency estimation * single SNP and haplotype association tests * permutation testing for association significance * implementation of Paul de Bakker's Tagger tag SNP selection algorithm. * automatic download of phased genotype data from HapMap * visualization and plotting of PLINK whole genome association results including advanced filtering options Haploview is fully compatible with data dumps from the HapMap project and the Perlegen Genotype Browser. It can analyze thousands of SNPs (tens of thousands in command line mode) in thousands of individuals. Note: Haploview is currently on a development and support freeze. The team is currently looking at a variety of options in order to provide support for the software. Haploview is an open source project hosted by SourceForge. The source can be downloaded at the SourceForge project site. linkage disequilibrium, haplotype, genotype, visualization, analysis, single nucleotide polymorphism, gene, genetic, genomic, java is listed by: Genetic Analysis Software
is listed by: SoftCite
is related to: International HapMap Project
is related to: PLINK
has parent organization: Broad Institute
PMID:15297300
PMID:21356869
PMID:20147036
Free, Available for download, Freely available nif-0000-30472 http://www.broad.mit.edu/personal/jcbarret/haploview/ SCR_003076 2026-02-16 09:45:55 6933
SIMM
 
Resource Report
Resource Website
1+ mentions
SIMM (RRID:SCR_000849) software application, software resource, simulation software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 6th,2023. Gene dropping simulation software. The program is a gzip'ed tar archive and is designed to run under UNIX/Linux operating system. gene, genetic, genomic, software is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154626 http://mlemire.freeshell.org/software.html SCR_000849 SimM 2026-02-16 09:45:21 2
SVA
 
Resource Report
Resource Website
10+ mentions
SVA (RRID:SCR_002155) SVA software application, software resource, commercial organization Software package to annotate, visualize, and analyze the genetic variants identified through next-generation sequencing studies, including whole-genome sequencing (WGS) and exome sequencing studies. SVA aims to provide the research community with a user-friendly and efficient tool to analyze large amount of genetic variants, and to facilitate the identification of the genetic causes of human diseases and related traits. gene, genetic, genomic, annotate, visualize, genetic variant, next-generation sequencing, whole-genome sequencing, exome, sequencing, genome, disease, trait, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Duke University School of Medicine; North Carolina; USA
PMID:21624899 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154666, OMICS_00190, biotools:sequencevariantanalyzer http://www.svaproject.org/
https://bio.tools/sequencevariantanalyzer
SCR_002155 Sequence Variant Analyzer, SVA: Sequence Variant Analyzer 2026-02-16 09:45:39 16

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