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http://xula.eagle-i.net/i/00000139-25f8-4557-8dd7-9ade80000000

Core facility that provides the following services: Drug Dosage Form Development. The center is focused on understanding and overcoming barriers to efficient oral, colonic, parenteral, pulmonary and vaginal delivery of drugs in the hopes of developing new treatments for chronic diseases such as cancer. Numerous new technologies are coming out of the Center as relationships have been formed with small, advanced technology businesses.

Proper citation: XULA Center for Nanomedicine and Drug Delivery (RRID:SCR_010215) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000134-fc0b-ad1d-77e4-a45080000000

Core facility that provides the following services: X-ray crystallography service. A Molecular Structure and Modeling Core laboratory has been established to provide technical services to support faculty researchers involved in cancer research and drug design at Xavier University. Drug design methods use molecular structure information and modeling methods to determine structure patterns among active and inactive compounds, identify and compare potential active sites, and screen databases to identify new leads. X-ray crystallography provides structure coordinates for druglike, organic compounds and small peptides. The goal of this core laboratory is to provide small molecule X-ray crystallographic services as well as to support ligand-based and structure-based drug design projects at any stage. The long term goal is to develop resources in order to enhance cancer related biomedical research capability at Xavier University. To achieve this goal, the Molecular Structure and Modeling Core Laboratory has set the following specific aims: 1. To provide salary support for a Core Scientist to provide molecular modeling services and training in support of Xavier faculty research projects 2. To establish new collaborations with faculty at other local and RCMI institutions who might benefit from molecular modeling services 3. To provide small molecule x-ray crystallography services 4. To provide support and maintenance costs for equipment in the MSM Core

Proper citation: XULA RCMI Molecular Structure and Modeling Core (RRID:SCR_010219) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-3637-992d-dacb-da6080000000

Core facility that provides the following services: Cytometric Bead Array, Meso Scale Discovery''s Multi-Array��, Cytometry protein measurements, Elispot Assays, Phenotypic analysis with flow cytometry, Multifunctional/Polychromatic flow cytometry (7-14 color), Cell proliferation assays, Tetramer/pentamer staininng, Influenza hemagglutination inhibition assay, Bordetella pertussis ELISA IgG / IgA, Commercial ELISA. The Immunology Core provides assistance to investigators with sample processing, storage, shipping, documentation, assay design, assay development and evaluation of immune responses. It is the goal of the core to monitor immune responses during clinical trials using the latest advances in technology and provide practical applications of this technology to evaluating immune responses. We continue to develop new immune monitoring technology with industry and academic collaborators. The Immunology Core has extensive experience in assay development and optimization, and will assist in the selection of appropriate assays and antigens during the protocol/developmental phase of a study or trial.

Proper citation: Vanderbilt Human Immunology Core Laboratory (RRID:SCR_010182) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c63a-c759-b341-4bb480000000

The mission of the Innovative Translational Research Shared Resource (ITR) is to advance the translation of basic and clinical research into improved clinical therapies by facilitating clinical discoveries and managing laboratory and clinical data exchange between researchers. The ITR has partnered with the Personalized Cancer Medicine Initiative (PCMI) and the Vanderbilt-Ingram Cancer Center (VICC) to characterize the molecular changes present in tumors. With a focus in clinical sample preparation and tumor genetic analyses, the ITR uses the most advanced laboratory techniques to uncover the genetic uniqueness of each patient''s tumor for research. This knowledge will lead to improved clinical therapies and a more personalized cancer care that will save lives and improve patient outcomes. The ITR gives scientific and technical assistance to clinical and laboratory researchers interested in experimentation using human tumor tissues or cell lines. In addition to our expertise in genetic analyses, the ITR is also interested in partnering with clinical investigators to study clinical phenotypes in a research laboratory. These studies are tailored to the needs of the clinical investigator.

Proper citation: Vanderbilt Innovative Translational Research Shared Resource (RRID:SCR_010183) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-7bc7-c4a0-480b-864680000000

The Vanderbilt Institute of Nanoscale Science and Engineering (VINSE) is a University institute focused on new science and technology based on nanoscale materials. We carry out frontier science and technology by teaming locally and globally, and providing an environment where physicists, chemists, biologists, and all engineers may collaboratively solve forefront problems and create new scientific understanding.

Proper citation: Vanderbilt Institute of Nanoscale Science and Engineering (RRID:SCR_010187) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-b69c-150b-b341-4bb480000000

Mass spectrometry is used to analyze the complex array of lipids in cellular membranes in an effort to dissect precursor-product relationships in lipid signaling networks.

Proper citation: Vanderbilt Lipidomics Core Laboratory (RRID:SCR_010188) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-114b-ebaa-dacb-da6080000000

Core facility that provides the following services: Assay Design and Development, High Throughput Screening and automated data analysis. The biology and screening team is responsible for developing, adapting, and automating the HTS assay from the benchtop assay provided by the collaborator. We work closely with the providing researcher to insure that the assay is rapidly moved into high-throughput screening. Once the assay has been validated, the screening of the small molecule library begins. Generally, the screen is expanded to accommodate the full compound library; however, structure-specific searches can be made if the required reagents are limited or costly.

Proper citation: Vanderbilt High Throughput Screening Facility (RRID:SCR_010180) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-5f47-d5a9-d7c8-cf3780000000

This laboratory houses an impressive collection of high-end microscopes including one of the most powerful transmission electron microscopes in the world. The microscope is kept in a specially designed space that inhibits intrusive vibrations. Its atomic resolution is propelling world-class research in nanotechnology, biology, chemistry, geology, engineering and medicine. The laboratory''s microscopes are accessible to trained collaborators from other institutions.

Proper citation: UTSA Kleberg Advanced Microscopy Laboratory (RRID:SCR_010146) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-2f42-aa68-d7c8-cf3780000000

Core facility that provides the following services: Computational systems biology data analysis assistance, Biological computational software installation service. The objective of the Computational Systems Biology Core facility (CSBC) is to provide computational support for basic and translational health research at UTSA with the following specific aims: - Build the computational infrastructure to support modeling and simulation of biological systems - Live cell imaging - Protein Biomarker research

Proper citation: UTSA RCMI Computational Systems Biology Core (RRID:SCR_010148) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-f9ee-8ac6-3c2e-1e5380000000

The mission of The Neurostatistics Core is to promote the use of the most effective and current biostatistical methods among Neuroscience faculty and students, and to make these methods more generally available. It is designed to overcome the communication gap between experimental neuroscientists and statisticians by integrating statistical experts, in the form of Applied Biostatistics PhD students, directly into the laboratories of SNRP Project Investigators.

Proper citation: UTSA SNRP Neurostatistics Core (RRID:SCR_010153) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/0000013d-037f-b425-afc0-9aeb80000000

VANTAGE (Vanderbilt Technologies for Advanced Genomics) is a genomics core laboratory consolidation initiated by an $8.6 million ARRA funded NIH grant award to Vanderbilt University Medical Center, with an overall goal of creating a new collaborative shared resource that accelerates discovery in genome sciences and personalized medicine, providing state-of-the art research shared resource facilities and technology.

Proper citation: VANTAGE (RRID:SCR_010155) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a235-587c-b4bd-8a1180000000

The Informatics Shared Resource catalyzes the research productivity of VICC investigators by providing a flexible physical and electronic infrastructure for acquiring, storing, communicating and analyzing data arising from wet bench, translational, and clinical cancer research as well as senior staff and faculty level assistance in the interpretation of research datasets using state-of-the-art analysis.

Proper citation: VICC Research Informatics (RRID:SCR_010156) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-114e-e025-dacb-da6080000000

Core facility that provides the following services: Custom Polyclonal Antibody Services, Monoclonal antibody isotyping, Hybridoma Services, Antigen production and purification, Peptide Synthesis, Peptide conjugation to protein carriers (ex. KLH, BSA), Recombinant Protein Expression and Purification Services, Kinetic Analyses for Protein:Protein and Protein:Small Molecule Interactions, Sample Lysis and Preparation. The Vanderbilt Antibody and Protein Resource (VAPR) partners both with scientists locally and from across the country to design and develop reagents for research, diagnostics, and large-molecule therapeutics.

Proper citation: Vanderbilt Antibody and Protein Resource (RRID:SCR_010158) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c62b-0ffa-b341-4bb480000000

Core facility that provides the following services: Biospecimen processing and analysis, DNA/RNA extraction and banking, Genotyping. The Molecular Epidemiology Laboratory provides genotyping and other lab services for large-scale studies to Vanderbilt investigators related to biological specimen collection and storage, as well as biomarker and genetic marker assays.

Proper citation: Vanderbilt Biospecimen Shared Resource (RRID:SCR_010162) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-1124-673f-dacb-da6080000000

The Center for Molecular Neuroscience (CMN) at the Vanderbilt University School of Medicine supports interdisciplinary research and training in cellular and molecular neurobiology. Internationally recognized faculty approach the intricacies of neurogenesis, neural signaling and synaptic plasticity using leading-edge techniques in state-of-the-art research facilities.

Proper citation: Vanderbilt Center for Molecular Neuroscience Cores (RRID:SCR_010166) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-547c-89f8-0b67-095480000000

The Pharmaceutical Sciences Research Support Unit responds directly to the Chair of the Pharmaceutical Sciences Department. Its mission is to promote research by making available to offering our investigators instruments such as HPLCs, GC-MSs, NMR, among others and facilitating physical complementary spaces.

Proper citation: UPR Pharmaceutical Science Research Support Unit (RRID:SCR_010131) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250d-df05-43fb-601a80000000

The Translational Proteomics Center provides training, resources, and tools for new and established investigators seeking to use innovative approaches of proteomics to their research, as well as to undergraduate and graduate students in the biomedical field. The Center fosters collaborations and partnerships among researchers aiming to reduce health disparities, including infectious diseases, cancer, and neurological/neurodegenerative diseases. Currently located at the second floor of the Comprehensive Cancer Center, Laboratory # 5.

Proper citation: UPR RCMI Translational Proteomics Center (RRID:SCR_010133) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-9dd1-fddf-95a5-371e80000000

Core facility that provides the following services: Necropsy. The Sabana Seca Field Station (SSFS) is the administrative headquarters for the Caribbean Primate Research Center, or CPRC. This area contains offices, a clinic, and laboratories for reproductive biology and bone densitometry, necropsy and maintenance buildings. It houses rhesus monkeys from the CS colony or from the CS genetic line.

Proper citation: UPR Sabana Seca Field Station Caribbean Primate Research Center (RRID:SCR_010134) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-2bf2-d33a-5b95-f21080000000

Core facility that provides the following services: RNA extraction, Immunofluoresence assay, Dendritic cell immunophenotyping, ELISA, Polymerase chain reaction service, Florescence activated cell sorting service, Western blot analysis service. Research interests include: immunogenicity and protective efficacy of multi-clade consensus ENV SHIV virus-like particle vaccine, cellular innate activation as a tactic to prevent HIV-1 transmission, molecular changes after serial DV infections in macaques, and immunization of rhesus macaques with a dengue vaccine candidate based on a Venezuelan Equine Encephalitis (VEE) replicon vector.

Proper citation: UPR Virology Laboratory (RRID:SCR_010136) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-aa21-2db4-bfc0-fe9780000000

Core facility that provides the following services: Confocal microscope access, Flow cytometry analyzer access, FACS Cell Sorting, Cell culture technique training, Cryopreservation of cultured cells, Cell culture analysis assistance, Preparation of high titer viral stock, Flow cytometry for cytotoxicity assay, Viral plaque assay, Real-time imaging of cell cultures, Mycoplasma testing, Treatment of cell lines contaminated with mycoplasma, Provide SF-9 cell suspension, Establishment of seed stocks, AnnexinV-FITC/PI assay. The Cell Culture and High Throughput Screening (HTS) Core Facility is a comprehensive research cell-culturing and cytometry facility established in 2007, as part of the Border Biomedical Research Center (BBRC). This facility was conceived to provide investigators, students and other researchers access to state-of-the-art technology for conducting experiments related to cellular, immune and physiological responses to stress, infectious agents, and toxicants. The laboratory also provides assistance and training related to cell culture techniques and equipment operation . The 1,756 sq ft core facility includes 6 individual cell culture suites that are available 24/7 to any researchers that have completed in-house training. The core also provides customized project support for experimental design and data analysis. The integration of the Cell Culture and HTS Core Laboratories has allowed investigators to screen a large number of compounds for their therapeutic potential against pathogens, cancer, and other diseases.

Proper citation: UTEP Cell Culture and High Throughput Screening Core Facility (RRID:SCR_010140) Copy   

•   Source: SciCrunch Registry