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http://harvard.eagle-i.net/i/0000012c-e1a8-0ec0-2162-17a280000000

Core facility that provides the following services: Introduction to the GE In Cell Analyzer 1000 for High Content Analysis (HCA). In collaboration with GE Healthcare Bio-sciences, the NeuroDiscovery Center has established a program centered around the IN Cell Analyzer 1000 - a flexible and easy to use sub-cellular analysis system suitable for medium-throughput screening, assay development and basic research. Based in the NeuroDiscovery Laboratory for Drug Discovery in Neurodegeneration, the IN Cell Analyzer 1000 is available for use by NeuroDiscovery members. (While priority is given to members investigating neurodegenerative diseases and the central nervous system, we welcome enquiries from all investigators.)

Proper citation: Harvard NeuroDiscovery Center - Cell-based Assays Core (RRID:SCR_009852) Copy   

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http://harvard.eagle-i.net/i/0000012c-e198-9f3f-2162-17a280000000

High quality statistical support is important in the preparation of grant applications or study protocols for clinical trials. Such support typically is not readily available to investigators who are new to clinical trials. To address this weakness, the NeuroDiscovery Center provides consulting and collaborative services to its members who are engaged in clinical research applicable to neurodegenerative disease.

Proper citation: Harvard NeuroDiscovery Center - Biostatistics Consultation (RRID:SCR_009850) Copy   

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http://harvard.eagle-i.net/i/0000012b-00c4-8067-db6e-7a3f80000000

Core facility that provides the following services: Transgene microinjection service, Embryonic stem cell gene targeting service, Blastocyst injection service, Cryopreservation of embryos and sperm, Genotyping service, Mouse consulting service. The Genome Modification Facility (GMF) provides transgenic, gene targeting, and other services to investigators of Harvard University and its affiliated institutions, as well as to investigators within the US and abroad. The GMF performs microinjections of DNA into fertilized embryos to generate transgenic mice, DNA transfection into ES cells for the creation of recombinant ES cell clones, injection of gene-targeted ES cells into host blastocysts to generate gene knock-out or knock-in mice, teratoma formation studies, and other related ES cell-based services. Other services include cryopreservation of mouse sperm and embryos, in vitro fertilization (IVF), recovery of cryopreserved mouse sperm and embryos, rederivation of pathogen free mouse lines, and derivation ES cell lines from wild type and mutant mice with a variety of genetic backgrounds. Our staff provides general consultations on experimental designs and vectors for gene modification-related projects, DNA preparation, recombinant ES clones, mouse genotyping, colony breeding and husbandry. We can also customize services as requested to support development of animal models of human diseases.

Proper citation: Harvard Genome Modification Facility Harvard University (RRID:SCR_009849) Copy   

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http://harvard.eagle-i.net/i/0000012e-021d-e404-b2b9-4d8780000000

Core facility that provides the following services: ABI Prism Taqman Allelic Discrimination Assay, OpenArray SNP genotyping, Illumina genotyping, Custom Illumina GoldenGate genotyping, Illumina Infinium genotyping analysis, Illumina methylation analysis. The Partners Genotyping Facility, part of the Partners HealthCare Center for Personalized Genetic Medicine (PCPGM), provides flexible, high quality, high-throughput SNP genotyping to the Harvard-Partners research community, including Harvard Medical School, hospitals in the Partners HealthCare network, investigators in the Dana-Farber-/ Harvard Cancer Center, and the Harvard School of Public Health. The portfolio of Genotyping methods at PCPGM now includes Illumina, TaqMan and TaqMan OpenArrays. Note: DF/HCC members will receive the DF/HCC discount on both genotyping and sequencing services from our facility

Proper citation: Harvard PCPGM Genotyping Facility (RRID:SCR_009846) Copy   

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http://harvard.eagle-i.net/i/0000012b-00bf-9941-db6e-7a3f80000000

Core facility that provides the following services: Macromolecular X-ray diffraction service, Charge density analysis, Single-Crystal service, Crystal mounting service, Cambridge structural database access, Inorganic crystal structure database access. The X-ray diffraction facility in Harvard University offers single crystal X-ray data collection, structure solution and refinement of small molecule structures.

Proper citation: Harvard FAS Center for Crystallographic Studies (RRID:SCR_009843) Copy   

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http://harvard.eagle-i.net/i/0000012f-e9e7-e67c-de5a-673e80000000

Core facility that provides the following services: Access to fabrication lab. Technological advances hold a key to greater understanding of the structure and function of complex neural circuits. Neuroengineering is a core facility that provides customized engineering solutions to neuroscience problems faced by our members. Assistance with experimental design, electronics, machining, and software development, are all services provided.

Proper citation: Harvard FAS Center for Brain Science - Neuroengineering Core Facility (RRID:SCR_009841) Copy   

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http://harvard.eagle-i.net/i/0000012d-edfa-7bc7-b2b9-4d8780000000

Core facility that provides the following services: 96-well plasmid preparation service.

The Center for Computational and Integrative Biology (CCIB) Automation Core provides the greater Partners research community with high-throughput automation services as well as special automation project design and implementation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: MGH CCIB Automation Core (RRID:SCR_009914) Copy   

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http://ohsu.eagle-i.net/i/0000012e-5e3a-7084-4106-535b80000000

In cooperation with the Data and Clinical Cores at the Layton Center, the Biomarkers and Genetics Core generates and maintains biomarker data for select biomarkers which have established roles in the characterization of subjects with or at risk of dementia. Biological markers of brain aging, dementia risk, and neurodegeneration have the potential to accelerate the identification of disease mechanisms and treatment strategies. Biomarkers may include genes, proteins, or other metabolites, and may be identified in DNA, cerebrospinal fluid (CSF), or plasma. Apolipoprotein E (APOE) genotype is generated for all research subjects. Sub-groups of subjects have other types of biomarker data. Many subjects have had genome-wide SNP data generated. In order to foster collaborative research as well as expand resources and expertise, samples (DNA, CSF, and plasma) and data are distributed to qualified investigators worldwide. Most of these researchers are pursuing the causes and modifiers of dementia. Data and samples are collected from well characterized research subjects including the healthy elderly and dementia patients.

Proper citation: Layton Alzheimers Disease Center Biomarkers and Genetics Core Lab (RRID:SCR_009911) Copy   

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http://ohsu.eagle-i.net/i/0000012e-5e56-c3be-4106-535b80000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6th,2022. The Oregon Alzheimer?s Disease Center?s (OADC) Clinical Core program, directed by Dr. Jeffrey Kaye, performs longitudinal studies of the natural history of brain aging and Alzheimer''s disease in patients and healthy control volunteers. These studies which are performed through standardized neurological, neuro-psychological, and brain-imaging assessments are carried out in the Alzheimer''s Disease and Memory Assessment Clinics as well as through community-based assessments conducted in the homes of study volunteers. The Layton Center Neuroimaging Lab conducts brain-imaging MRI brain scans to assist in diagnosis of brain disease. Typically, MRI images are taken from three different planes. These planes are known as the coronal plane, sagittal plane and the axial plane. Each series of MRI images is named after the plane from which they were obtained. The Clinical Core?s research is focused on preclinical and early Alzheimer?s disease (AD) yet is also poised to participate in other relevant new research as it arises. The OADC Clinical Core recruits, assesses and follows individuals from population groups at high risk for dementia such as: the healthy ?oldest old?, subjects with family history of AD, and subjects with Mild Cognitive Impairment (MCI). Research with underserved populations The Oregon Alzheimer?s Disease Center also maintains two Satellite programs to enhance understanding of underserved populations: The Klamath Exceptional Aging Project (KEAP) is a community-based study of brain aging being conducted in Klamath Falls. The African American Dementia and Aging Project (AADAPt) s a Portland-based cohort of 100 African American seniors.

Proper citation: Layton Alzheimers Disease Center Clinical Core (RRID:SCR_009912) Copy   

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http://harvard.eagle-i.net/i/0000012f-0d5e-aceb-cb22-be8c80000000

Implements and maintains specialized computer facilities required by the DERC investigators. A major emphasis of JoslinResearch.org is to provide dynamic web applications that serve essential informational needs of the research community at the Joslin Diabetes Center. These applications provide such functions as automating media provisioning services to DERC laboratories, distributing DERC event schedule information, providing access to troubleshooting information, fully-searchable call schedules with contact information, text messaging services, and access to information about Section, Investigator and Fellow projects and affiliations. All applications adhere to the JoslinResearch.org paradigm of distributed administration without requiring knowledge of web design or web programming. For DERC use only.

Proper citation: JDC Computer Resource (RRID:SCR_009877) Copy   

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http://hunter-cuny.eagle-i.net/i/00000136-7e06-6aac-949b-425080000000

The Flow-Cytometry (FACS) facility is located on the ninth floor of the Hunter North building. This facility provides analyses of up to 7 parameters in eukaryotic cell populations and sorts cells under sterile conditions. These analyses can be used to identify and isolate rare cell populations, determine chromosome ploidy in individual cells, study apoptosis, and study cell-signaling among other applications.

Proper citation: Hunter Flow Cytometry Facility (RRID:SCR_009870) Copy   

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http://xula.eagle-i.net/i/00000135-67c4-1e5a-77e4-a45080000000

Core facility that provides the following services: Microscopy, Imaging, and Analysis, Routine Histopathology, Specialized Histopathology. The purpose of this core laboratory is to assist investigators requiring detection, imaging, and morphometric analysis of gene and protein expression in any type of cell and tissue. Services, expertise and state-of -the-art biomedical imaging services will be provided with the hope of broadening and streamlining all morphological research.

Proper citation: LCRC Morphology and Imaging Core (RRID:SCR_009908) Copy   

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http://ohsu.eagle-i.net/i/0000012e-5dd8-5be1-4106-535b80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5th,2022. The Education and Information Core of the Layton Aging & Alzheimer?s Disease Center develops and carries out a wide range of educational programs to: * Increase public awareness and understanding of Alzheimer''s Disease research, * Aid in the recruitment of subjects for research studies, and * Improve care and quality of life for persons with dementia and support their family caregivers. Our educational activities include: * Training for health care professionals which include seminars and lectures and we also provide ?hands-on? experiences for medical students, * Community education on Alzheimer''s disease and related dementia disorders, * Workshops on doctor ? patient communication for families and caregivers, * Collaboration with community organizations and groups to promote awareness of the disease and publicize research activities, a particular focus is underserved populations including rural communities and minority groups, * Collaboration with other organizations that serve patients and families, e.g., the Alzheimer?s Association and other state and local agencies that serve the elderly and the loved ones who care for them, and * Distribution of printed material that provides topical information on a variety of subjects related to Alzheimer?s disease and dementia and how best to provide quality of life to those with the disease. * A newsletter, Aging & Alzheimer''s Update, which is published twice per year. The Education Core administers the Oregon Income Tax Check-off Alzheimer''s Research Fund in collaboration with The Oregon Partnership for Alzheimer''s Research, a community advisory committee.

Proper citation: Layton Aging and Alzheimers Disease Center Education Core (RRID:SCR_009909) Copy   

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http://xula.eagle-i.net/i/00000135-1b74-64ae-77e4-a45080000000

Core facility that provides the following services: FACS service, Flow cytometry analysis service, Data archival. The Cell Analysis & Immunology Core Facility is a customer oriented service dedicated to supporting the research needs of the investigators of the Louisiana Cancer Research Consortium (LCRC). It provides state-of-art instrumentation and expertise for addressing experimental issues related to single cells, nuclei and chromosomes. In addition to instrumentation, the Facility intends to collaborate with the investigators and contribute to all aspects of the research process. This includes consultation in experimental design, technical assistance in the operation of instruments, trouble shooting, data analysis and storage, interpretation of results and preparation and production of presentation graphics. The Facility is also communicating with investigators in other institutions and is devoted to introducing and developing new applications on our flow cytometers. In this way, investigators are provided with unlimited possibilities to answer questions regarding nature and function of cells by flow cytometry.

Proper citation: LCRC Cell Analysis and Immunology Core Facility (RRID:SCR_009905) Copy   

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http://hunter-cuny.eagle-i.net/i/00000136-8336-80a6-949b-425080000000

Core facility that provides the following services: Bio-imaging instrumentation training, Bio-Imaging data analysis service. The Bio-Imaging facility currently provides optical and video microscopy services.The facility is equiped with two confocal microscopes, a Leica TCS SP2, and a Perkin Elmer UltraVIEW ERS Spinning Disc confocal . In addtion to confocal microscopy the facility is also equipped for bright field, phase contrast, modulation contrast and epi fluorescence microscopy. The facility has two separate wide field image analysis stations. A Nikon Optiphot microscope equipped with a color video system and Compix imaging software, and a Nikon Eclipse TE200 inverted scope. This inverted scope in specially configured to perform calcium ratio imaging is equipped with Molecular Devices Meta Fluor software The facility has recently expanded with the aquisition of a JEOL JEM-100C/CX Transmission Electron Microscope. The facility also is equiped with Typhoon 9410 scanner for the quantitation and localization of sub cellular fluorescent and radioactive molecules. In addition a Densitometer allows for the analysis of 1 and 2 D gels, Southern, northern and western blots and RFPL gels. The facility is also equipped with color and B&W laser printers for the production of publication quality graphics and presentation materials.

Proper citation: Hunter Bio-Imaging Facility (RRID:SCR_009869) Copy   

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http://howard.eagle-i.net/i/00000134-a517-1426-bf4c-ca4080000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core for bioinformatics consultation and software access. Laboratory of Molecular Computations and Bioinformatics (LMCB) is a resource facility dedicated to the support of computational biomedical research at Howard University. Provides molecular modeling, molecular dynamics, bioinformatics, and computational quantum chemistry capabilities and support to a variety of research projects at Howard University.

Proper citation: Howard University Center for Computational Biology and Bioinformatics Core Facility (RRID:SCR_009864) Copy   

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http://harvard.eagle-i.net/i/00000139-4a28-1319-4d8e-943b80000000

The Partners Research Computing Core was created by Enterprise Research Infrastructure & Services (ERIS) to offer dedicated services, consultation, and support within the teaching hospitals. Please check the service catalog as new services are added, or contact us if you need a consultation. Initial discussion is at no charge.

Proper citation: Harvard Partners Research Computing Core (RRID:SCR_009861) Copy   

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http://montana.eagle-i.net/i/0000012b-00be-16ed-df3b-3fdc80000000

Core facility that provides the following services: Lab animal technician services, Animal husbandry service.

The Mission of the Animal Resources Center is to provide healthy animals for use in IACUC-approved research, educational and testing protocols at Montana State University,ensure that University research animals are cared for in a humane and appropriate manner by the provision of modern, well maintained facilities, trained personnel, technical support, veterinary care and monitoring of animal care and use, provide resources, technical assistance, and information for University researchers and educators in meeting the requirements of animal-related protocols, and ensure observance of ethical standards and federal regulations pertaining to the care and use of animals for research, education and testing at Montana State University.

Proper citation: MSU Animal Resource Center (RRID:SCR_009936) Copy   

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http://msm.eagle-i.net/i/0000012b-00c2-e053-353c-df7f80000000

The Analytical Chemistry and Protein Profiling Core is comprised of three primary labs: * Analytical Chemistry * Protein Profiling/2D Gel * 2D Gel Electrophoresis Lab

Proper citation: MSM Analytical Chemistry and Protein Profiling Core (RRID:SCR_009933) Copy   

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http://msm.eagle-i.net/i/0000012b-00c2-b0bd-353c-df7f80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 25, 2019. Core focuses on integration of MSM and affiliated health information systems into an interoperable repository. The long-term goal is to establish an integrated standards-based informatics platform to support MSM clinical and translational research investigators in their own work and in sharing research information with collaborators and other investigators in parallel fields.

Proper citation: Morehouse School of Medicine Biomedical Informatics Unit (RRID:SCR_009934) Copy   

•   Source: SciCrunch Registry