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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.dana.org/resources/brainweb/
BrainWeb provides information and links to validated sites about brain diseases and disorders. These include outside resources reviewed by scientific advisers, as well as articles in Dana publications. Sites listed in BrainWeb detail common brain diseases and disorders, and include general neuroscience and health resources. They offer descriptions of conditions, frequently asked questions, organization contacts, and sources for more information. BrainWeb and its links are suitable for lay readers, including students and educators, as well as people with brain disorders, their families, and caregivers.
Proper citation: Dana Foundation: BrainWeb (RRID:SCR_007996) Copy
http://www.scripps.edu/np/inia/index.html
Consortium set out to identify the molecular, cellular, and behavioral neuroadaptations that occur in the brain reward circuits associated with the extended amygdala and its connections. It is hypothesized that genetic differences and/or neuroadaptations in this circuitry are responsible for the individual differences in vulnerability to the excessive consumption of alcohol. Chronic exposure to alcohol results in neuroadaptive phenomena, including tolerance, sensitization, dependence, withdrawal, loss of control of drinking, and relapse that contribute to the development of excessive alcohol consumption. The INIA has the following goals: 1) To establish animal models to study specific neurobiological targets for vulnerability that lead to excessive consumption of alcohol at the molecular, cellular and neural circuit level of analysis, 2) To identify specific clusters of genes whose expression is regulated by alcohol and which are responsible for any given model of excessive alcohol consumption using gene expression arrays, differential display, mutagenesis directed at specific brain areas, and the development of new informatics tools to analyze and interpret gene expression, cellular circuitry and brain circuitry data with the use of transgenic and knockout approaches, and 3) To attract new and innovative investigators to the field of alcohol research by recruiting individuals for development of U01 grants and pilot projects and by developing online interactive capacity among INIA scientists and others, and by making the neuroinformatics integrated data sets accessible, searchable and interactive with other databases for all scientists interested in alcoholism research. The structure of INIA is envisioned as two domains, Dependence-induced drinking and Binge drinking, comprised of multiple U01 research grants. The flow of information within each domain moves from molecular, to cellular, to neurocircuitry levels of analysis. These U01s share information with the core facilities, which act as data depositories. The Administrative Core coordinates the flow of information among the Domains and Cores and disseminates the information back to the U01s. A Pilot Project program will identify exciting new areas for research and the continual recruitment of new investigators to the alcohol field. The INIA program is directed by an Administrative Core in close cooperation with the Animal Models, Gene Array and Neurocircuitry Cores via a Steering Committee and with the continual advice of the Scientific Advisory Committee.
Proper citation: Integrative Neuroscience Initiative on Alcoholism (RRID:SCR_008042) Copy
http://www.nia.nih.gov/research/dn
A funding resource that supports the research and training for understanding the structure and function of the aging nervous system, with an emphasis on studies involving Alzheimer's disease and age-related dementia. There is an emphasis on brain-behavior relationships. This program is composed of three branches: Neurobiology, Neuropsychology, and Dementias of Aging. The overall aim of this program is to understand the aging nervous system to minimize mental decline and improve the lives of older patients. This resource also includes links to sites for Alzheimer's disease (AD) studies that include: specimen repositories, genetic materials, bio-markers, data, policies on NIA and AD genetics sharing plans, and additional aging or other AD related links.
Proper citation: National Institute on Aging, Division of Neuroscience (RRID:SCR_008257) Copy
http://brainconnection.positscience.com/
An educational site providing accessible information about how the brain works and how people learn
Proper citation: Brain Connection (RRID:SCR_008315) Copy
http://www.alivelearn.net/xjview8/
A viewing program for Statistical Parametric Mapping (SPM2, SPM5 and SPM8). p-value slider, displays multiple images at a time and can be used to build Region of Interest (ROI) masks. For a given region you can find the anatomical name and search the selected region in online database (wiki, Google scholar and PubMed).
Proper citation: xjView: A Viewing Program For SPM (RRID:SCR_008642) Copy
http://www.alzresearch.org/index.cfm
A Alzheimer's Disease Research Center (ADRC) whose goal is to conduct basic and clinical research aimed at understanding Alzheimer's disease. The Center enrolls a variety of individuals for clinical trials, evaluation and follow-up, including: normal control subjects, individuals with mild memory problems, and patients diagnosed with Alzheimer's Disease or related dementias. Researchers can request data and specimens obtained from ADRC subjects. These include blood or DNA, brain specimens, and cross-sectional or longitudinal clinical and cognitive data, all from ADRC subjects.
Proper citation: Johns Hopkins Alzheimer's Disease Research Center (RRID:SCR_008757) Copy
http://www.bri.ucla.edu/research/resources
Brain bank resources which include postmortem human frozen brain tissue and matched cerebrospinal fluid (CSF) and blood available for scientists to search for etiopathogeneses of human disease. The National Neurological Research Specimen Bank and the Multiple Sclerosis Human Neurospecimen Bank maintains a collection of quick frozen and formalin fixed postmortem human brain tissue and frozen cerebrospinal fluid from patients with neurological diseases, including Alzheimer's Disease, amyotrophic lateral sclerosis, depressive disorder/suicide, and epilepsy, among others. Diagnoses are documented by clinical medical records and gross/microscopic neuropathology. The Neuropathology Laboratory at the UCLA Medical Center maintains a bank of frozen, formalin and paraformaldehyde-fixed and paraffin-embedded postmortem human brain tissues and frozen cerebrospinal fluid (CSF) from patients who die with Alzheimer's disease and other dementing and degenerative illnesses, as well as control materials removed in a similar fashion from patients who are neurologically normal.
Proper citation: Brain Research Institute Biobank Resources (RRID:SCR_008756) Copy
http://mayoresearch.mayo.edu/mayo/research/dickson_lab/
A brain bank and laboratory focused on memory and motor disorders. Brains are sent to the laboratory for diagnosis and research for the State of Florida Alzheimer Disease Initiative and for the Society for Progressive Supranuclear Palsy. As part of this brain banking function, fixed and frozen brain samples are obtained at autopsy and sent to the laboratory for diagnostic evaluation and for various types of research studies. The major types of analyses performed on the brain samples include neuro-histology, immunohistochemistry, confocal microscopy, electron microscopy and image analysis, as well as immunoassays. The latter are based upon Western blotting and enzyme linked immunoassays. The laboratory has a specific interest in the interface between normal aging and Alzheimer's disease, as well as in non-Alzheimer's degenerative disorders such as Lewy body dementia, corticobasal degeneration, progressive supranuclear palsy and frontotemporal dementia. The primary focus of research on aging is neuropathologic characterization of brains of individuals who had been prospectively and longitudinally evaluated during life. These studies aim to determine differences in a range of biologic parameters in brains of people with normal cognitive, mild cognitive impairment and dementia. Their focus on Parkinson's disease is to identify preclinical Parkinson's disease in order to develop means for early diagnosis.
Proper citation: Mayo Clinic Jacksonville: Neuropathology and Microscopy (RRID:SCR_008753) Copy
https://www.humanconnectome.org/software/connectome-workbench
Software brain visualization, analysis and discovery tool for fMRI and dMRI brain imaging data, including functional and structural connectivity data generated by the Human Connectome Project. Used to map brain imaging data. Allows for visualization of outputs from HCP pipelines from single subject, or average data from group of subjects and register that data onto standard brain atlas.
Proper citation: Connectome Workbench (RRID:SCR_008750) Copy
Consortium to comprehensively map long-distance brain connections and their variability. It is acquiring data and developing analysis pipelines for several modalities of neuroimaging data plus behavioral and genetic data from healthy adults.
Proper citation: Human Connectome Coordination Facility (RRID:SCR_008749) Copy
http://www.rad.upenn.edu/sbia/braid/braid_web/index.html
Large-scale archive of normalized digital spatial and functional data with an analytical query mechanism. One of its many applications is the elucidation of brain structure-function relationships. BRAID stores spatially defined data from digital brain images which have been mapped into normalized Cartesian coordinates, allowing image data from large populations of patients to be combined and compared. The database also contains neurological data from each patient and a query mechanism that can perform statistical structure-function correlations. The project is developing database technology for the manipulation and analysis of 3-dimensional brain images derived from MRI, PET, CT, etc. BRAID is based on the PostgreSQL server, an object/relational DBMS, which allows a standard relational DBMS to be augmented with application-specific datatypes and operators. The BRAID project is adding operations and datatypes to support querying, manipulation and analysis of 3D medical images, including: * Image Datatypes: BRAID supports a family of 3D image datatypes, each having an abstract type and an implementation type. Abstract types include boolean (for regions of interest), integer, float, vector (for representing morphological changes), tensor (for representing derivatives and standard deviations of vector images) and color. Implementation types at present include line-segment format and voxel array. * Image Operators: BRAID supports addition of images, multiplication (which is interpreted as intersection for boolean images), coercion of an image''s abstract or implementation type to another value, and determination of volumes of regions of interest. * Statistical Operators: A chi-squared test has been added to SQL as an aggregate operator on pairs of boolean values. * Web Interface: A general-purpose Web gateway allows the results of queries that return computed images to be displayed. You can download the BRAID source code 2.0. This version is developed under postgreSQL 7.3.4., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: BRAID (RRID:SCR_008702) Copy
http://www.mssm.edu/research/centers/alzheimers-disease-research-center/
A research facility and clinical program that is dedicated to the study and the treatment of both normal aging and Alzheimer's disease. This facility will accommodate requests for its resources (for example, data or tissue) from investigators that are not funded by the ADRC. Their team is composed of experts in geriatrics, geriatric psychiatry and psychology, neurology, pathology, and radiology. All team members work to provide services to those with memory disorders. This center sponsors educational programs for healthcare professionals and community groups. Data from the ADRC cores are available to all ADRC investigators after approval from the PI who collected the data. Data generated by the ADRC cores are communicated to the National Alzheimer's Coordinating Center (NACC) and can be available through them. Tissue can be distributed after approval of the Tissue Allocation Committee, and can be used for further research.
Proper citation: Mount Sinai Alzheimer's Disease Research Center (RRID:SCR_008780) Copy
http://alzheimers.med.umich.edu/research/resources-for-investigators/
An organization that provides scientists with human tissue from Alzheimer's patients and patients with related brain disorders. Brain tissue is collected from research studies at the University of Michigan, as well as other research centers, and are donated by the families of the patients or the participants themselves. Tissues that are present in the Brain Bank are pre-characterized by pathologists and can be provided to researchers upon request.
Proper citation: Michigan Alzheimer's Disease Center Brain Bank (RRID:SCR_008774) Copy
http://www.opwdd.ny.gov/institute-for-basic-research/home
A research arm of the New York State Office for People with Developmental Disabilities (OPWDD), which conducts basic and clinical research into the causes, treatment, and prevention of intellectual disabilities and other developmental disabilities. The goals of the IBR's research, services and education program are designed to provide prevention, earlier detection, and improved treatment of intellectual disabilities and other developmental disabilities. This research program has a total of 46 laboratories over 7 departments. These programs include the George A. Jervis Clinic (a tertiary-level diagnostic and research clinic), the Specialty Clinical Laboratories (conduct specialty testing for genetic, metabolic, neurodegenerative disorders), and the Comprehensive Genetic Disease Program at Richmond County (provides genetics and genetic counseling services). This institute provides educational activities in the graduate studies program, and the Programs in Developmental Neuroscience and Developmental Disabilities (PDNDD). The PDNDD collaborates with the faculty from the City University of New York and the State University of New York. The IBR staff regularly conducts public education workshops and professional seminars about developmental disabilities.
Proper citation: Institute for Basic Research in Developmental Disabilities (RRID:SCR_008806) Copy
http://brainbank.med.miami.edu/
A biomaterial supply resource which collects and disseminates over 1500 brains and links tissue specimens to patient data. The Brain Endowment Bank distributes brain tissue specimens to scientists worldwide who are investigating neurodegenerative and neuropsychiatric diseases, as well as to scientists involved in ongoing studies on the affects of aging. Its overall objective is to support basic and clinical research activities by providing a systematic method for obtaining detailed pre-mortem clinical information, developing procedures for optimizing brain autopsies, cryopreserving neuropathological specimens, and obtaining neuropathological diagnoses after death.
Proper citation: UM Brain Endowment Bank (RRID:SCR_008721) Copy
https://www.uab.edu/medicine/alzheimers/
The UAB Alzheimer's Disease Center provides comprehensive treatment for Alzheimer's patients while also promoting research for the prevention and cure of Alzheimer's disease and related disorders. The ADC is an interdisciplinary program of scientists working in areas including neurology, psychiatry, genetics, and psychology. The Center provides comprehensive treatment and promotes research for the prevention and/or cure of Alzheimer's disease and other related disorders with memory loss and impaired cognition. A major emphasis of research is the maintenance of a clinical research database comprised of neurological, medical, and neuropsychological test data from participants seen in the ADRC Clinical study since 1999, many of whom have been followed for several years in the study.
Proper citation: UAB Alzheimer's Disease Center (RRID:SCR_004305) Copy
http://www.brainnet-europe.org/
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 7, 2022. Consortium of 19 brain banks across Europe with an aim to harmonize neuropathological diagnostic criteria and develop gold standards for quality, safety and ethics standards for brain banking. BrainNet Europe also contributes to research on rare diseases, such as: Pick''s disease or other rare forms of dementia, as well as to questions after the events in the aging brain. Anyone can be a donor - irrespective of disease of the central nervous system or not, because for research purposes, one does not only need tissue samples from ill donors, but also from healthy ones for comparison.
Proper citation: BrainNet Europe (RRID:SCR_004461) Copy
http://www.epilepsy.ie/index.cfm/spKey/research.html
Epilepsy Research Ireland is a non-profit organization (Charity CHY17527), run by a group of volunteers, who are dedicated to find cure for epilepsy by raising awareness and money for research. We can say cure now with much more confidence than we could even 10 years ago because recent advances in genetics, brain imaging and drug therapy, all hold out the promise of that holy grail the cure. We can also say with confidence that you can be part of that push by participating in this new foundation since we have collaborations with doctors and scientists all over Europe, the US and Australia, all of whom share the same goal. Epilepsy research, conducted by Epilepsy Research Ireland, is essential and will deliver benefits across the board. Research planned and already underway by Epilepsy Research Ireland will help develop and improve clinical skills; it will provide a knowledge base to develop new ways to manage and treat epilepsy; it will help in the evaluation of new medical advances. Ultimately we can improve the quality of care and provide greater understanding, better and more accurate diagnosis and more tailored treatments. Ireland is uniquely well-positioned, given its relatively homogenous population to make the goal, of making real discoveries in epilepsy research that will directly improve the lives of people with epilepsy, a realistic one.
Proper citation: Epilepsy Research Ireland (RRID:SCR_004448) Copy
http://caintegrator-info.nci.nih.gov/rembrandt
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 28,2023. REMBRANDT is a data repository containing diverse types of molecular research and clinical trials data related to brain cancers, including gliomas, along with a wide variety of web-based analysis tools that readily facilitate the understanding of critical correlations among the different data types. REMBRANDT aims to be the access portal for a national molecular, genetic, and clinical database of several thousand primary brain tumors that is fully open and accessible to all investigators (including intramural and extramural researchers), as well as the public at-large. The main focus is to molecularly characterize a large number of adult and pediatric primary brain tumors and to correlate those data with extensive retrospective and prospective clinical data. Specific data types hosted here are gene expression profiles, real time PCR assays, CGH and SNP array information, sequencing data, tissue array results and images, proteomic profiles, and patients'''' response to various treatments. Clinical trials'''' information and protocols are also accessible. The data can be downloaded as raw files containing all the information gathered through the primary experiments or can be mined using the informatics support provided. This comprehensive brain tumor data portal will allow for easy ad hoc querying across multiple domains, thus allowing physician-scientists to make the right decisions during patient treatments., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Repository of molecular brain neoplasia data (RRID:SCR_004704) Copy
http://www.ukmstissuebank.imperial.ac.uk/news3d.html
Procures brain, spinal cord and other tissues bequeathed by donors and makes them available to scientists investigating the cause and treatment of multiple sclerosis. The Tissue Bank achieves this aim by addressing the following objectives: # Increasing the awareness of the importance of human tissue to research amongst the MS and scientific communities. # Being sensitive to the needs of the tissue donor and responsive to the requirements of scientists when collecting and processing donated tissue. # Making available high quality, well-documented samples of tissue to research scientists working to better understand MS. There are approximately 85 000 people with multiple sclerosis in the United Kingdom. The varied symptoms experienced by all these people result from damage taking place within their brain and spinal cord. Understanding the exact nature of this damage is essential if we are to better treat the condition. Vital information about how the brain and spinal cord are damaged in multiple sclerosis can be obtained by using a multitude of experimental approaches to study the affected tissue from people with MS and ''control'' tissue from people without the disease. The donation of tissue for research is therefore fundamental to furthering our understanding of the causes of multiple sclerosis and to developing more effective treatments for the disease. The UK Multiple Sclerosis Tissue Bank welcomes requests for tissue samples for use in research into the cause and treatment of multiple sclerosis. It has available post mortem, cryopreserved brain and spinal cord tissue both fixed and unfixed, and cerebrospinal fluid from patients with and without a history of multiple sclerosis. Freshly dissected tissue samples, or those preserved using unconventional techniques may also be made available by prior arrangement.
Proper citation: UK Multiple Sclerosis Tissue Bank (RRID:SCR_004609) Copy
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