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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
OligoPicker
 
Resource Report
Resource Website
1+ mentions
OligoPicker (RRID:SCR_008720) OligoPicker software resource Software to help selecting up to five oligo probes for each of the DNA sequences you provided for microarray spotting. is listed by: OMICtools PMID:12724288 GNU General Public License, Acknowledgement requested OMICS_00830 SCR_008720 2026-02-14 02:01:38 3
Biodoop
 
Resource Report
Resource Website
Biodoop (RRID:SCR_008711) Biodoop software resource A suite of parallel bioinformatics applications based upon a popular open-source Java implementation of MapReduce, Hadoop. mapreduce/hadoop is listed by: OMICtools OMICS_01224 SCR_008711 2026-02-14 02:01:43 0
DrGaP
 
Resource Report
Resource Website
10+ mentions
DrGaP (RRID:SCR_008670) DrGaP software resource Designed to identify Driver Genes and Pathways in cancer genome sequencing studies. is listed by: OMICtools Cancer OMICS_00149 SCR_008670 2026-02-14 02:01:43 10
InVEx
 
Resource Report
Resource Website
1+ mentions
InVEx (RRID:SCR_008734) InVEx software resource A permutation-based method (written in Python) for ascertaining genes with a somatic mutation distribution showing evidence of positive selection for non-silent mutations. is listed by: OMICtools
has parent organization: Broad Institute
OMICS_00151 SCR_008734 Introns Vs Exons 2026-02-14 02:01:44 4
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) sequence analysis software, data processing software, data analysis software, software application, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks
https://bio.tools/cufflinks
https://sources.debian.org/src/cufflinks/
SCR_014597 2026-02-14 02:02:57 8838
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) software resource, simulation software, software application Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-02-14 02:02:45 11
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) sequence analysis software, data processing software, data analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka
https://sources.debian.org/src/prokka/
https://sources.debian.org/src/prokka/
SCR_014732 2026-02-14 02:03:02 4876
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) sequence analysis software, data visualization software, data processing software, data analysis software, software application, software resource Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview
https://sources.debian.org/src/seaview/
SCR_015059 2026-02-14 02:03:01 1777
GIIRA
 
Resource Report
Resource Website
1+ mentions
GIIRA (RRID:SCR_015507) sequence analysis software, data processing software, data analysis software, software application, software resource Gene prediction method that identifies potential coding regions based on the mapping of reads from an RNA-Seq experiment. gene prediction, rna seq, coding region, potential coding region is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btt577 Available for download OMICS_07360 http://www.rki.de/EN/Content/Institute/DepartmentsUnits/JuniorGroups/JRG4.html
https://sources.debian.org/src/giira/
SCR_015507 2026-02-14 02:03:06 3
GREAT: Genomic Regions Enrichment of Annotations Tool
 
Resource Report
Resource Website
50+ mentions
GREAT: Genomic Regions Enrichment of Annotations Tool (RRID:SCR_005807) GREAT data analysis service, analysis service resource, production service resource, source code, service resource, software resource Data analysis service that predicts functions of cis-regulatory regions identified by localized measurements of DNA binding events across an entire genome. Whereas previous methods took into account only binding proximal to genes, GREAT is able to properly incorporate distal binding sites and control for false positives using a binomial test over the input genomic regions. GREAT incorporates annotations from 20 ontologies and is available as a web application. The utility of GREAT extends to data generated for transcription-associated factors, open chromatin, localized epigenomic markers and similar functional data sets, and comparative genomics sets. Platform: Online tool term enrichment, cis-regulatory region, function, gene, genomic, annotation, ontology, chromatin immunoprecipitation, sequencing, chip-seq, comparative genomics, transcription factor binding is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: PRISM (Stanford database)
is related to: Gene Ontology
has parent organization: Stanford University School of Medicine; California; USA
Bio-X ;
Howard Hughes Medical Institute ;
Stanford University; California; USA ;
Packard ;
Searle Scholar ;
Microsoft Research ;
Alfred P. Sloan Foundation ;
Edward Mallinckrodt Jr. Foundation ;
NIH ;
Human Frontier Science Program fellowship LT000896/2009-l;
NICHD 1R01HD059862;
NHGRI R01HG005058;
NSF CCF-0939370;
DFG Hi 1423/2-1
PMID:20436461
PMID:23814184
Free for academic use, Acknowledgement requested nlx_149295, OMICS_00635 SCR_005807 Genomic Regions Enrichment of Annotations Tool (GREAT), Genomic Regions Enrichment of Annotations Tool 2026-02-14 02:01:10 82
InterProScan
 
Resource Report
Resource Website
5000+ mentions
InterProScan (RRID:SCR_005829) web service, data processing software, data analysis service, analysis service resource, data analysis software, production service resource, service resource, software application, data access protocol, software resource Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service. functional, analysis, sequence, protein, nucleotide, predict, presence, domain, site, proteome, genome, metagenome, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: RARTF
is related to: InterPro
is related to: LegumeIP
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
European Union ;
Biotechnology and Biological Sciences Research Council ;
EMBL
PMID:15980438
PMID:17202162
PMID:24451626
Free, Available for download, Freely available OMICS_01479, biotools:interproscan_4, nlx_149337 https://www.ebi.ac.uk/interpro/download.html
https://bio.tools/interproscan_4
SCR_005829 InterProScan Sequence Search, InterProScan 2, InterProScan 3, InterProScan 4, InterProScan 5 2026-02-14 02:01:11 6936
Whatizit
 
Resource Report
Resource Website
1+ mentions
Whatizit (RRID:SCR_005824) Whatizit web service, data analysis service, analysis service resource, production service resource, service resource, data access protocol, software resource A text processing system that allows you to do textmining tasks on text. It is great at identifying molecular biology terms and linking them to publicly available databases. Whatizit is also a Medline abstracts retrieval/search engine. Instead of providing the text by Copy&Paste, you can launch a Medline search. The abstracts that match your search criteria are retrieved and processed by a pipeline of your choice. Whatizit is also available as 1) a webservice and as 2) a streamed servlet. The webservice allows you to enrich content within your website in a similar way as in the wikipedia. The streamed servlet allows you to process large amounts of text. textual analysis, protein, gene, gene ontology, text-mining, annotation, literature analysis is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: UniProt
is related to: MEDLINE
is related to: NCBI Taxonomy
has parent organization: European Bioinformatics Institute
Free for academic use OMICS_01200, nlx_149329 http://www.ebi.ac.uk/webservices/whatizit SCR_005824 2026-02-14 02:01:10 8
SPLINTER
 
Resource Report
Resource Website
10+ mentions
SPLINTER (RRID:SCR_005826) SPLINTER software resource Software that detects and quantifies short IN/DELs as well as single nucleotide substitutions in pooled-DNA samples. is listed by: OMICtools
has parent organization: Washington University in St. Louis; Missouri; USA
Cancer Free for academic / non-profit use, Commercial use requires license OMICS_00100 SCR_005826 Short IN/DEL Prediction by Large deviation Inference and Non-linear True frequency Estimation by Recursion 2026-02-14 02:01:01 13
UCSC Genome Browser
 
Resource Report
Resource Website
10000+ mentions
Rating or validation data
UCSC Genome Browser (RRID:SCR_005780) portal, data or information resource, service resource, database, project portal Portal to interactively visualize genomic data. Provides reference sequences and working draft assemblies for collection of genomes and access to ENCODE and Neanderthal projects. Includes collection of vertebrate and model organism assemblies and annotations, along with suite of tools for viewing, analyzing and downloading data. Reference, sequence, assembly, collection, genome, visualize, genomic, data, ENCODE, Neanderthal, project, sequencing is used by: VizHub
is used by: Blueprint Epigenome
is used by: QmRLFS-finder
is used by: International Human Epigenome Consortium Data Portal
is used by: iPiG
is listed by: re3data.org
is listed by: OMICtools
is listed by: Educational Resources in Neuroscience
is listed by: SoftCite
is related to: HEXEvent
is related to: PicTar
is related to: Phenotree
is related to: Enhancer Trap Line Browser
is related to: CistromeFinder
is related to: ENCODE
is related to: Human Epigenome Atlas
is related to: ENCODE
is related to: BigWig and BigBed
is related to: PhenCode
is related to: doRiNA
is related to: ISCA Consortium
is related to: WashU Epigenome Browser
is related to: CRISPOR
is related to: liftOver
is related to: kent
has parent organization: University of California at Santa Cruz; California; USA
works with: TarBase
UC BIOTEuropean UnionH ;
Alfred P. Sloan Foundation ;
David and Lucille Packard Foundation ;
NIH ;
HHMI ;
CISI ;
NHGRI ;
DOE ;
NSF DBI 9809007;
NIGMS GM52848
PMID:12045153
PMID:22908213
PMID:23155063
OMICS_00926, SCR_017502, nif-0000-03603, SciEx_217, SCR_012479, r3d100010243 http://genome.cse.ucsc.edu
https://doi.org/10.17616/R3RK5C
SCR_005780 The Human Genome Browser at UCSC, UCSC Genome Browser Group, University of California at Santa Cruz Genome Browser, UCSC Genome Bioinformatics 2026-02-14 02:01:11 10026
SeqGSEA
 
Resource Report
Resource Website
10+ mentions
SeqGSEA (RRID:SCR_005724) SeqGSEA data analysis software, software resource, data processing software, software application Software package that provides methods for gene set enrichment analysis of high-throughput RNA-Seq data by integrating differential expression and splicing. It uses negative binomial distribution to model read count data, which accounts for sequencing biases and biological variation. Based on permutation tests, statistical significance can also be achieved regarding each gene''s differential expression and splicing, respectively. differential expression, gene expression, gene set enrichment, rna-seq, sequencing, splicing is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v3 or newer OMICS_02251 SCR_005724 SeqGSEA - Gene Set Enrichment Analysis (GSEA) of RNA-Seq Data: integrating differential expression and splicing 2026-02-14 02:01:09 34
ESTScan
 
Resource Report
Resource Website
100+ mentions
ESTScan (RRID:SCR_005742) ESTScan data analysis software, software resource, data processing software, software application ESTScan is a program that can detect coding regions in DNA sequences, even if they are of low quality. ESTScan will also detect and correct sequencing errors that lead to frameshifts. ESTScan is not a gene prediction program , nor is it an open reading frame detector. In fact, its strength lies in the fact that it does not require an open reading frame to detect a coding region. As a result, the program may miss a few translated amino acids at either the N or the C terminus, but will detect coding regions with high selectivity and sensitivity. ESTScan takes advantages of the bias in hexanucleotide usage found in coding regions relative to non-coding regions. This bias is formalized as an inhomogeneous 3-periodic fifth-order Hidden Markov Model (HMM). Additionally, the HMM of ESTScan has been extended to allows insertions and deletions when these improve the coding region statistics. dna, dna sequence, coding region, perl module, c, btlib perl module is listed by: Debian
is listed by: OMICtools
has parent organization: SourceForge
PMID:10786296 OMICS_08423, nlx_149202 https://sources.debian.org/src/estscan/ SCR_005742 ESTScan project 2026-02-14 02:01:09 289
caArray
 
Resource Report
Resource Website
10+ mentions
caArray (RRID:SCR_006053) caArray data repository, storage service resource, data or information resource, service resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on Sep 18, 2018. Open-source, web and programmatically accessible microarray data management system. caArray guides the annotation and exchange of array data using a federated model of local installations whose results are shareable across the cancer Biomedical Informatics Grid (caBIG). caArray furthers translational cancer research through acquisition, dissemination and aggregation of semantically interoperable array data to support subsequent analysis by tools and services on and off the Grid. As array technology advances and matures, caArray will extend its logical library of assay management. microarray, gene expression, data sharing, service resource, data management, annotation, interoperability, life sciences is listed by: re3data.org
is listed by: OMICtools
is related to: Cancer Biomedical Informatics Grid
is related to: MAGE-TAB
has parent organization: National Cancer Institute
Cancer THIS RESOURCE IS NO LONGER IN SERVICE nlx_151452, OMICS_00864, r3d100010573 https://doi.org/10.17616/R33G76 SCR_006053 caArray - Array Data Management System, caArray Data Portal 2026-02-14 02:01:12 35
MetaQC
 
Resource Report
Resource Website
10+ mentions
MetaQC (RRID:SCR_006000) software resource Software for quality control and diagnosis for microarray meta-analysis. Quantitative quality control measures include: (1) internal homogeneity of co-expression structure among studies (internal quality control; IQC); (2) external consistency of co-expression structure correlating with pathway database (external quality control; EQC); (3) accuracy of differentially expressed gene detection (accuracy quality control; AQCg) or pathway identification (AQCp); (4) consistency of differential expression ranking in genes (consistency quality control; CQCg) or pathways (CQCp). For each quality control index, the p-values from statistical hypothesis testing are minus log transformed and PCA biplots were applied to assist visualization and decision. Results generate systematic suggestions to exclude problematic studies in microarray meta-analysis and potentially can be extended to GWAS or other types of genomic meta-analysis. The identified problematic studies can be scrutinized to identify technical and biological causes (e.g. sample size, platform, tissue collection, preprocessing etc) of their bad quality or irreproducibility for final inclusion / exclusion decision. standalone software, mac os x, unix/linux, windows, r, FASEB list is listed by: OMICtools
has parent organization: CRAN
PMID:22116060 GNU General Public License, v2 OMICS_04032 https://github.com/donkang34/MetaQC SCR_006000 MetaQC: Objective Quality Control and Inclusion/Exclusion Criteria for Genomic Meta-Analysis, MetaQC: Objective Quality Control and Inclusion / Exclusion Criteria for Genomic Meta-Analysis 2026-02-14 02:01:03 40
DiseaseMeth
 
Resource Report
Resource Website
10+ mentions
DiseaseMeth (RRID:SCR_005942) data repository, storage service resource, data or information resource, service resource, database Human disease methylation database. DiseaseMeth version 2.0 is focused on aberrant methylomes of human diseases. Used for understanding of DNA methylation driven human diseases. disease, methylation, dna methylation, genome, gene, epigenetics, epigenomics, methylome, bio.tools is listed by: 3DVC
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Harbin Medical University; Heilongjiang; China
National Natural Science Foundation of China ;
Natural Science Foundation of Heilongjiang Province ;
State Key Laboratory of Urban Water Resource and Environment ;
Scientific Research Fund of Heilongjiang Provincial Education Department
PMID:22135302
PMID:27899673
Free,Freely available OMICS_01838, nlx_151289, biotools:diseasemeth, SCR_017488 http://bioinfo.hrbmu.edu.cn/diseasemeth
https://bio.tools/diseasemeth
http://202.97.205.78/diseasemeth/ SCR_005942 , Disease Meth-The Human Disease Methylation Database, DiseaseMeth database, DiseaseMeth version 2.0 2026-02-14 02:01:12 34
BLESS
 
Resource Report
Resource Website
10+ mentions
BLESS (RRID:SCR_005963) BLESS sequence analysis software, data processing software, data analysis software, software application, software resource, algorithm resource Software tool for Bloom-filter-based error correction for next-generation sequencing (NGS) reads. The algorithm produces accurate correction results with much less memory. c++, next-generation sequencing, bloom-filter, error correction, ngs, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24451628 GNU General Public License v3 OMICS_02246, biotools:bless https://bio.tools/bless SCR_005963 BLoom-filter-based Error correction Solution for high-throughput Sequencing reads, BLESS - Bloom-filter-based Error Correction Tool for NGS reads 2026-02-14 02:01:03 45

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