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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.med.unc.edu/microbiome
Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) Copy
https://einsteinmed.edu/centers/diabetes-research/human-Islet-and-adenovirus-core/
Core which provides methodologies, technology and infrastructure to support investigators in the use of human islets for research studies for the Einstein-Mount Sinai Diabetes Research Center. It isolates and prepares human and rodent islets/beta cells and cell lines for investigator-initiated research and generates specific viral vectors (adenovirus and lentivirus) for gene delivery of cDNAs and shRNAs of interest to beta cells and other islet cell types.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core Facility (RRID:SCR_015066) Copy
https://einsteinmed.edu/research/shared-facilities/barc/
Core provides information and tools for Einstein and Montefiore investigators from initial study planning stage through analysis and data output. Facility services include: mass spectrometry analysis, including stable isotopes, as well as research-grade determination of lipids, and metabolic markers for human subjects and animal model projects; High-throughput robotics for semi-automated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS); Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays; Research quality analysis of metabolites for human and animal samples using Olympus AU400 autoanalyzer; Advanced training in analytical chemistry.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility (RRID:SCR_015067) Copy
https://www.derc.cuimc.columbia.edu/services/translational-biomarker-analytical-core
Core makes available to Diabetes Research Center investigators variety of high quality radio-immunoassay, ELISA, and other analytical methods, and facilitates access of DRC investigators to measurement of small molecules by targeted and untargeted metabolomics/lipidomics with the Irving Institute Biomarkers Core. TBAC also provides consultations and services for in vivo methods to measure insulin secretion and sensitivity.
Proper citation: Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility (RRID:SCR_015077) Copy
Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) Copy
https://einsteinmed.edu/centers/diabetes-research/biomedical-cores/animal-physiology/
Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) Copy
http://www.baderc.org/cores/transgenicCore.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice.
Proper citation: Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/administrative.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that typically organizes a meeting with the investigator/user and relevant core directors to discuss the different services and tests that the Diabetes Research Center would recommend to the investigator. It also provides support letters for grant proposals submitted by investigators.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Administrative Core (RRID:SCR_015087) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/latino-network/
Research network dedicated to supporting translation research in diabetes prevention and control. The core has a strong emphasis on sociocultural adaption for Latinos in the U.S and can provide expertise in Latino biopsychosocial research.
Proper citation: New York Regional Center for Diabetes Translation Research Latino Network for Diabetes Translational Research (RRID:SCR_015189) Copy
http://diabetesresearch.med.umich.edu/Core_MCDTR_Methods.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Research core that works to assist investigators in designing studies, collecting data, and analyzing data to examine questions related to the causes, prevention, and control of diabetes, its complications, and comorbidities.
Proper citation: Michigan Center for Diabetes Translational Research Methods and Measurements Core (RRID:SCR_015188) Copy
http://www.einstein.yu.edu/centers/liver-research/research-cores/special-animals-core.aspx
Core that provides resources, technologies and scientific expertise to advance translational applications of animal and human liver cells. It also provides bred animals for research, isolation and culture of animal and human liver cells, as well as provision of cell culture additives and materials.
Proper citation: Marion Bessin Liver Research Center Animal Models Stem Cells and Cell Therapy (RRID:SCR_015181) Copy
Core that supports and assists with use of specialized instrumentation, including laser scanning confocal microscopy, deconvolution microscopy, multi-photon microscopy, cryo-electron microscopy (cryo-EM) and correlative light electron microscopy (CLEM). It also provides expertise in and assistance with specialized imaging techniques such as correlative microscopy, vesicle tracking, volumetric measurements, ultrastructural sample preparation, super resolution fluorescence microscopy (STORM/SIM), Fluorescence Recovery After Photobleaching (FRAP), Fluorescence Resonance Energy Transfer (FRET) and Total Internal Reflection Microscopy (TIRF).
Proper citation: Marion Bessin Liver Research Center Imaging and Cell Structure (RRID:SCR_015182) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/timc/
Core facility that supports research that addresses the prevention and control of diabetes using a social-ecological approach to address the dynamic interrelations of biological, psychological and social factor at a personal and environmental level.
Proper citation: New York Regional Center for Diabetes Translation Research Translational Intervention Methodology Core (RRID:SCR_015180) Copy
Core that provides Liver Research Center investigators an extensive array of customized viral and non-viral vectors, viral and non-viral vectors for reprogramming somatic cells, generating special non-viral vectors, consultation for study design and, if appropriate, data analysis.
Proper citation: Marion Bessin Liver Research Center Genetic Engineering and Gene Therapy (RRID:SCR_015186) Copy
Core that provides services ranging from classical qPCR and RT-qPCR plus specialized preparation of miRNA and development of targeted genotyping assays.
Proper citation: Molecular Biology and Next Generation Technology (RRID:SCR_015184) Copy
http://drc.ucsf.edu/mouse-genetics-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 5,2024. Core that provides a shared resource for the establishment of mutant mouse models for DRC research. It coordinates DRC members with contacts to a number of UCSF-wide facilities for knock-out/knock-in and transgenic mouse generation.
Proper citation: University of California San Francisco Diabetes Research Center Mouse Genetics Core Facility (RRID:SCR_015109) Copy
http://www.uab.edu/shp/drc/administrative-core-links
Core responsible for the scientific, education/enrichment, and fiscal operations of the DRC. Their goal is to assure the growing vitality of an intellectual community and a highly productive research program in diabetes by effective deployment of DRC resources for the benefit of our investigators, patients, and trainees.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Administrative Core Facility (RRID:SCR_015108) Copy
http://www.uab.edu/shp/drc/bioanalytical-redox-biology-core-barb-links
Core which promotes redox biology in diabetes-related research. It promotes research in areas common to the metabolic and vascular aspects of diabetes and cardiovascular disease. The core provides services in mitochondrial damage, function, proteomics, and oxidative stress assessment support for investigators carrying out diabetes mellitus (DM) and cardiometabolic disease (CMD) research at UAB.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Bioanalytical REDOX Biology Core Facility (RRID:SCR_015113) Copy
https://cdtr.wustl.edu/our-cores/communication-and-literacy/
Core facility whose services include assisting with outreach and recruitment to various populations, developing strategic community partnerships, and developing materials and methods for effective health education within the community.
Proper citation: Washington University Center for Diabetes Translation Research Health Communication and Health Literacy Core (RRID:SCR_015198) Copy
http://www.uab.edu/shp/drc/human-physiology-core-links
Core which incorporates and combines expertise and technology for assessment of hormones and other analytes in both humans and animal models; body composition and fat distribution; insulin sensitivity and substrate metabolism; energy expenditure; and cardiovascular function.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Human Physiology Core Facility (RRID:SCR_015111) Copy
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