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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GoPubMed
 
Resource Report
Resource Website
10+ mentions
GoPubMed (RRID:SCR_005823) GoPubMed data or information resource, database, service resource A web server which allows users to explore PubMed search results with the Gene Ontology, a hierarchically structured vocabulary for molecular biology. GoPubMed submits a user''''s keywords to PubMed, retrieves the abstracts, detects Gene Ontology terms in the abstracts, displays the subset of Gene Ontology relevant to the original query, and allows the user to browse through the ontology displaying associated papers and their GO annotation. Platform: Online tool other analysis, literature curation and exploration, gene ontology, pubmed, literature, bio.tools is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: PubMed
has parent organization: Biotechnology Center of the TU Dresden
European Union IST-2004-506779 PMID:15980585 Free for academic use biotools:gopubmed, nlx_149328, OMICS_01183 https://bio.tools/gopubmed SCR_005823 2026-02-15 09:19:03 29
Expression Profiler
 
Resource Report
Resource Website
1+ mentions
Expression Profiler (RRID:SCR_005821) Expression Profiler service resource, analysis service resource, data analysis service, production service resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The EP:GO browser is built into EBI's Expression Profiler, a set of tools for clustering, analysis and visualization of gene expression and other genomic data. With it, you can search for GO terms and identify gene associations for a node, with or without associated subnodes, for the organism of your choice. other analysis, cluster, analysis, visualization, gene expression, genomic, gene ontology, gene association, microarray, protein-protein interaction, gene, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: European Bioinformatics Institute
European Union ;
Wellcome Trust ;
Estonian Science Foundation 5724;
Estonian Science Foundation 5722
PMID:15215431 THIS RESOURCE IS NO LONGER IN SERVICE biotools:expression_profiler, nlx_149323 https://bio.tools/expression_profiler SCR_005821 Expression Profiler at the EBI 2026-02-15 09:19:13 6
PIRSF
 
Resource Report
Resource Website
10+ mentions
PIRSF (RRID:SCR_003352) PIRSF data or information resource, database, standard specification, narrative resource A SuperFamily classification system, with rules for functional site and protein name, to facilitate the sensible propagation and standardization of protein annotation and the systematic detection of annotation errors. The PIRSF concept is being used as a guiding principle to provide comprehensive and non-overlapping clustering of UniProtKB sequences into a hierarchical order to reflect their evolutionary relationships. The PIRSF classification system is based on whole proteins rather than on the component domains; therefore, it allows annotation of generic biochemical and specific biological functions, as well as classification of proteins without well-defined domains. There are different PIRSF classification levels. The primary level is the homeomorphic family, whose members are both homologous (evolved from a common ancestor) and homeomorphic (sharing full-length sequence similarity and a common domain architecture). At a lower level are the subfamilies which are clusters representing functional specialization and/or domain architecture variation within the family. Above the homeomorphic level there may be parent superfamilies that connect distantly related families and orphan proteins based on common domains. Because proteins can belong to more than one domain superfamily, the PIRSF structure is formally a network. The FTP site provides free download for PIRSF. protein annotation, classification, protein, superfamily, functional site, protein name, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
has parent organization: Protein Information Resource
NHGRI U01-HG02712;
NSF DBI-0138188;
NSF ITR-0205470
PMID:19455212
PMID:14681371
Free, Freely available biotools:pirsf, nif-0000-03294, OMICS_01697 https://bio.tools/pirsf http://pir.georgetown.edu/pirsf/ SCR_003352 PIR SuperFamily, Protein Information Resource SuperFamily 2026-02-15 09:18:32 28
Proteomics Identifications (PRIDE)
 
Resource Report
Resource Website
500+ mentions
Proteomics Identifications (PRIDE) (RRID:SCR_003411) PRIDE database, service resource, storage service resource, data repository, data or information resource Centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. Originally it was developed to provide a common data exchange format and repository to support proteomics literature publications. This remit has grown with PRIDE, with the hope that PRIDE will provide a reference set of tissue-based identifications for use by the community. The future development of PRIDE has become closely linked to HUPO PSI. PRIDE encourages and welcomes direct user submissions of protein and peptide identification data to be published in peer-reviewed publications. Users may Browse public datasets, use PRIDE BioMart for custom queries, or download the data directly from the FTP site. PRIDE has been developed through a collaboration of the EMBL-EBI, Ghent University in Belgium, and the University of Manchester. proteomics, protein, peptide, mass spectrometry, annotation, standard, spectra, protein-protein interaction, amino acid, amino acid sequence, post-translational modification, biomart, bio.tools is used by: ProteomeXchange
is used by: BioSample Database at EBI
is recommended by: NIDDK Information Network (dkNET)
is listed by: Biositemaps
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: HUPO Proteomics Standards Initiative
is related to: ProteomeXchange
has parent organization: European Bioinformatics Institute
Wellcome Trust WT085949MA;
European Union FP7 LSHG-CT-2006-036814;
European Union FP7 260558;
European Union FP7 262067;
European Union FP7 202272;
BBSRC BB/I024204/1
PMID:23203882
PMID:19662629
Free, Available for download, Freely available nif-0000-03336, biotools:pride, r3d100011515 https://www.ebi.ac.uk/pride/archive/
https://bio.tools/pride
https://doi.org/10.17616/R3F330
SCR_003411 PRoteomics IDEntifications database, PRIDE Archive - proteomics data repository, PRIDE Archive, PRIDE, Proteomics Identifications, Proteomics Identifications (PRIDE), PRoteomics IDEntifications database (PRIDE) 2026-02-15 09:18:33 642
SplicingCompass
 
Resource Report
Resource Website
1+ mentions
SplicingCompass (RRID:SCR_003249) software application, sequence analysis software, data processing software, software resource, data analysis software Software for detection of differential splicing between two different conditions using RNA-Seq data. differential splicing, splicing event, exon removal, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23449093 Free, Available for download, Freely available biotools:splicingcompass, OMICS_01340 https://github.com/KoenigLabNM/SplicingCompass SCR_003249 Splicing Compass 2026-02-15 09:18:31 2
deFuse
 
Resource Report
Resource Website
50+ mentions
deFuse (RRID:SCR_003279) software application, sequence analysis software, data processing software, software resource, software toolkit, data analysis software Software package for gene fusion discovery using RNA-Seq data. It uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. rna sequencing, gene fusion, paired end alignment, split read, fusion boundary, bio.tools uses: SAMTOOLS
uses: Bowtie
uses: BLAT
uses: GMAP
uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
British Columbia Cancer Foundation ;
Vancouver General Hospital Foundation ;
Genome Canada ;
Michael Smith Foundation for Health Research ;
Canadian Breast Cancer Foundation ;
Canadian Institutes of Health Research's Bioinformatics Training Program
PMID:21625565 Free, Available for download, Freely available biotools:defuse, OMICS_01345 https://sourceforge.net/projects/defuse/
http://compbio.bccrc.ca/software/defuse/
https://bio.tools/defuse
http://sourceforge.net/apps/mediawiki/defuse/index.php?title=Main_Page SCR_003279 2026-02-15 09:18:29 95
Cell Image Library (CIL)
 
Resource Report
Resource Website
10+ mentions
Cell Image Library (CIL) (RRID:SCR_003510) CIL database, service resource, storage service resource, data repository, data or information resource, image repository Freely accessible, public repository of vetted and annotated microscopic images, videos, and animations of cells from a variety of organisms, showcasing cell architecture, intracellular functionalities, and both normal and abnormal processes. Explore by Cell Process, Cell Component, Cell Type or Organism. The Cell includes images acquired from historical and modern collections, publications, and by recruitment. microscopic image repository, microscopic video repository, cell animation repository, bio.tools is used by: NIF Data Federation
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Cell Centered Database
is related to: Cell Centered Database
is related to: OME-TIFF Format
is related to: Integrated Manually Extracted Annotation
has parent organization: American Society for Cell Biology
has parent organization: University of California; San Diego;National Center for Microscopy and Imaging Research - NCMIR
has parent organization: University of California at San Diego; California; USA
is parent organization of: Biological Imaging Methods Ontology
NIGMS RC2 GM092708 PMID:34218671
PMID:34218673
Free, Freely available biotools:cellimagelibrary, nif-0000-37639, r3d100011601 http://www.cellimagelibrary.org/pages/about
https://bio.tools/cellimagelibrary
https://doi.org/10.17616/R3N92J
SCR_003510 Cell Image Library. CIL, Cell Image Library (CIL) 2026-02-15 09:18:34 19
Reactome
 
Resource Report
Resource Website
1000+ mentions
Reactome (RRID:SCR_003485) data analysis service, database, service resource, production service resource, data or information resource, analysis service resource Collection of pathways and pathway annotations. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways (signaling, innate and acquired immune function, transcriptional regulation, translation, apoptosis and classical intermediary metabolism) . Provides website to navigate pathway knowledge and a suite of data analysis tools to support the pathway-based analysis of complex experimental and computational data sets. pathway, interaction, reaction, nucleic acid, protein, complex, small molecule, signaling pathway, immune function, transcriptional regulation, translation, apoptosis, metabolism, ortholog, visualization, protein-protein interaction, web service, book, biomart, gold standard, bio.tools, FASEB list is used by: NIF Data Federation
is used by: DisGeNET
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: WikiPathways
is related to: Pathway Commons
is related to: ConsensusPathDB
is related to: FlyMine
is related to: AmiGO
is related to: PSICQUIC Registry
is related to: Integrated Molecular Interaction Database
is related to: NCBI BioSystems Database
is related to: MOPED - Model Organism Protein Expression Database
is related to: KOBAS
is related to: PSICQUIC Registry
is related to: Pathway Interaction Database
is related to: hiPathDB - human integrated Pathway DB with facile visualization
is related to: Algal Functional Annotation Tool
has parent organization: Ontario Institute for Cancer Research
has parent organization: Cold Spring Harbor Laboratory
has parent organization: European Bioinformatics Institute
has parent organization: New York University School of Medicine; New York; USA
works with: PathwayMatcher
Ontario Research Fund ;
European Molecular Biology Laboratory ;
NHGRI P41 HG003751;
European Union FP6 ENFIN LSHG-CT-2005-518254;
NIGMS GM080223;
NIGMS R01 GM100039
PMID:21082427
PMID:21067998
Open source, Public, Freely available r3d100010285, nif-0000-03390, biotools:reactome https://bio.tools/reactome
https://doi.org/10.17616/R3V59P
SCR_003485 Reactome Functional Interaction Network 2026-02-15 09:18:31 4282
eTRIKS
 
Resource Report
Resource Website
10+ mentions
eTRIKS (RRID:SCR_003765) eTRIKS organization portal, portal, service resource, consortium, data or information resource Research informatics and analytics platform for the IMI OncoTrack consortium. data sharing, drug discovery, translational research, informatics, knowledge management, metadata standard, platform, analytics, tool development, bio.tools uses: tranSMART
is used by: U-BIOPRED
is used by: Predict-TB
is used by: OncoTrack
is used by: ABIRISK
is used by: RA MAP
is listed by: Consortia-pedia
is listed by: Debian
is listed by: bio.tools
is related to: Roche
is related to: Janssen Research and Development
is related to: Merck
is related to: Pfizer Animal Genetics
is related to: Imperial College London; London; United Kingdom
is related to: French National Center for Scientific Research
is related to: Clinical Data Interchange Standards Consortium
is related to: University of Luxembourg; Luxembourg; Luxembourg
is related to: IDBS
is related to: BioSci Consulting
is related to: TraIT
is related to: EMIF
is related to: Open PHACTS
has parent organization: Imperial College London; London; United Kingdom
Innovative Medicines Initiative ;
EFPIA
PMID:29482119 biotools:eTRIKS, nlx_158034 https://bio.tools/eTRIKS SCR_003765 European Translational Information and Knowledge Management Services, European Translational Information & Knowledge Management Services 2026-02-15 09:18:34 10
L-Measure
 
Resource Report
Resource Website
10+ mentions
L-Measure (RRID:SCR_003487) LM software application, image processing software, data processing software, software resource, service resource, image analysis software A freely available software tool available for the Windows and Linux platform, as well as the Online version Applet, for the analysis, comparison and search of digital reconstructions of neuronal morphologies. For the quantitative characterization of neuronal morphology, LM computes a large number of neuroanatomical parameters from 3D digital reconstruction files starting from and combining a set of core metrics. After more than six years of development and use in the neuroscience community, LM enables the execution of commonly adopted analyses as well as of more advanced functions, including: (i) extraction of basic morphological parameters, (ii) computation of frequency distributions, (iii) measurements from user-specified subregions of the neuronal arbors, (iv) statistical comparison between two groups of cells and (v) filtered selections and searches from collections of neurons based on any Boolean combination of the available morphometric measures. These functionalities are easily accessed and deployed through a user-friendly graphical interface and typically execute within few minutes on a set of 20 neurons. The tool is available for either online use on any Java-enabled browser and platform or may be downloaded for local execution under Windows and Linux. neuronal morphology, neuroinformatics, branching analysis, digital reconstruction, analysis, comparison, bio.tools is listed by: 3DVC
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Computational Neuroanatomy Group
Human Brain Project ;
NINDS R01 NS39600
PMID:18451794 Public nif-0000-00003, biotools:l-measure http://www.nitrc.org/projects/lmeasure
https://bio.tools/l-measure
SCR_003487 2026-02-15 09:18:31 30
SeWeR - SEquence analysis using WEb Resources
 
Resource Report
Resource Website
SeWeR - SEquence analysis using WEb Resources (RRID:SCR_004167) portal, software resource, service resource, data or information resource, topical portal Sequence analysis using Web Resources (SeWeR) is an integrated, Dynamic HTML (DHTML) interface to commonly used bioinformatics services available on the World Wide Web. It is highly customizable, extendable, platform neutral, completely server-independent and can be hosted as a web page as well as being used as stand-alone software running within a web browser. It doesn''t require any server to host itself. The goal of SeWeR is to turn your web-browser into a powerful sequence-analysis tool. It is written entirely in JavaScript1.2. SeWeR can be downloaded and mirrored freely. The whole package is just around 300K. You can even run it from a floppy. SeWeR is not compatible with Netscape 6. SeWeR now generates graphics. Savvy is a plasmid drawing software that generates plasmid map in the revolutionary Scalable Vector Graphics format from W3C. nucleic acid, protein, pcr, alignment, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Centre for Cellular and Molecular Biology; Hyderabad; India
PMID:11395442 biotools:sewer, nlx_18981 https://bio.tools/sewer SCR_004167 SEquence analysis using WEb Resources, SeWeR 2026-02-15 09:18:38 0
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) software application, sequence analysis software, data processing software, software resource, software toolkit, data analysis software Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NSF DBI-0096033;
NSF DEB-9996118;
NIH R01 AI47745;
NIH U01 AI43638;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214;
NIGMS R01
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/
https://veg.github.io/hyphy-site/
https://github.com/veg/hyphy
https://bio.tools/HyPhy
SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-02-15 09:21:33 1497
zUMIs
 
Resource Report
Resource Website
100+ mentions
zUMIs (RRID:SCR_016139) software application, data processing software, data analysis software, software resource Software pipeline to process RNA-seq data with UMIs. The input to this pipeline is paired-end fastq files, where one read contains the cDNA sequence and the other read contains UMI and Cell Barcode information. single-cell, RNA-seq, UMI, Genomics, shell, r, perl, rna, cdna, cell, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1101/153940 Open source, Free, Available for download biotools:zumis https://bio.tools/zumis SCR_016139 zumi 2026-02-15 09:21:02 118
Fastml
 
Resource Report
Resource Website
100+ mentions
Fastml (RRID:SCR_016092) web service, data access protocol, web application, software resource Web application for the reconstruction of ancestral sequences. It computes maximum likelihood ancestral sequence reconstruction based on the phylogenetic relations between homologous sequences. ancestral, amino-acid, sequence, reconstruction, phylogenetic, relation, accurate, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Israel Science Foundation 878/09;
Bioinformatics Center at Tel-Aviv University
PMID:22661579 Free, Freely available biotools:fastml, OMICS_08650 https://bio.tools/fastml
https://sources.debian.org/src/fastml/
SCR_016092 The FastML Server 2026-02-15 09:21:01 109
BioPlex
 
Resource Report
Resource Website
1000+ mentions
BioPlex (RRID:SCR_016144) database, service resource, storage service resource, data repository, data or information resource Database of cell lines with each expressing a tagged version of a protein from the ORFeome collection. The overarching project goal is to determine protein interactions for every member of the collection. cell, line, protein, immunopurification, mass, spectrometry, interaction, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Harvard Medical School; Massachusetts; USA
NHGRI U41HG006673;
NIDDK K01 DK098285;
Canadian Institutes for Health Research
PMID:28514442 biotools:bioplex_2.0 https://bio.tools/bioplex_2.0 SCR_016144 BioPlex (biophysical interactions of ORFeome-based complexes), Harvard BioPlex, Biophysical Interactions of Orfeome-based comPLEXes (BioPLEX) 2026-02-15 09:21:48 1355
mentha
 
Resource Report
Resource Website
100+ mentions
mentha (RRID:SCR_016148) software application, data processing software, software resource, database, web application, data or information resource, data analysis software Software that archives evidence collected from different sources, then analyzes and presents these data. Its data come from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. protein, ppi, imex, interactome, archival, bio.tools, FASEB list uses: PSICQUIC Registry
is listed by: Debian
is listed by: bio.tools
is related to: IMEx - The International Molecular Exchange Consortium
PMID:23900247 biotools:mentha, r3d100011124 https://bio.tools/mentha
https://doi.org/10.17616/R3SP8V
SCR_016148 2026-02-15 09:21:32 149
DISULFIND
 
Resource Report
Resource Website
50+ mentions
DISULFIND (RRID:SCR_016072) Disulfinder software application, sequence analysis software, data processing software, software resource, data analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023, Software for predicting the disulfide bonding state of cysteines and their disulfide connectivity, starting from a protein sequence alone and may be useful in other genomic annotation tasks. predict, disulfide, bonding, state, cysteine, protein, sequence, genomic, annotation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: University of Florence; Florence; Italy
EU STREP APrIL II contract no. FP6-508861;
EU NoE BIOPATTERN contract no. FP6-508803;
Embark Fellowship from the Irish Research Council for Science ;
Engineering and Technology
PMID:16844986
DOI:10.1093/nar/gkl266
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04214, biotools:disulfind https://bio.tools/disulfind
https://sources.debian.org/src/disulfinder/
SCR_016072 Cysteines Disulfide Bonding State and Connectivity Predictor 2026-02-15 09:21:01 66
Exonerate
 
Resource Report
Resource Website
100+ mentions
Exonerate (RRID:SCR_016088) software application, data processing software, software resource, alignment software, image analysis software, software toolkit Software package for sequence alignment of pairwise sequence comparison. Exonerate can be used to align sequences using many alignment models, exhaustive dynamic programming, or a variety of heuristics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, pairwise, comparison, dynamic, programming, heuristic, bio.tools is used by: ExonerateTransferAnnotation
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:15713233 THIS RESOURCE IS NO LONGER IN SERVICE biotools:exonerate https://bio.tools/exonerate SCR_016088 2026-02-15 09:21:01 374
Necklace
 
Resource Report
Resource Website
1+ mentions
Necklace (RRID:SCR_016103) software application, data processing software, software resource, alignment software, image analysis software Software that combines reference and assembled transcriptomes for RNA-Seq analysis. It replaces many manual steps in the pipeline of RNA-Seq analyses involving species with incomplete genome or annotations. RNA, Transcriptome, Non-model species, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:28836999 Free, Available for download biotools:necklace https://bio.tools/necklace SCR_016103 Lace software 2026-02-15 09:21:31 3
Lifebit Deploit
 
Resource Report
Resource Website
1+ mentions
Lifebit Deploit (RRID:SCR_016428) data management software, software application, data analysis service, software resource, service resource, production service resource, analysis service resource Platform for computing management for data analysis on the cloud from the Lifebit company. Allows the computational analyses to be permanently linked to live analyses pipelines. Lifebit, compute, management, data, analysis, cloud, integrate, data, reproduce, transparent, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:28398311 Commercially available biotools:nextflow https://bio.tools/nextflow SCR_016428 2026-02-15 09:21:06 2

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