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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GWAMA
 
Resource Report
Resource Website
100+ mentions
GWAMA (RRID:SCR_006624) GWAMA data analysis software, software resource, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for meta analysis of whole genome association data. meta, analysis, genome, association, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:20509871
DOI:10.1186/1471-2105-11-288
THIS RESOURCE IS NO LONGER IN SERVICE biotools:gwama, OMICS_00235 https://bio.tools/gwama
https://sources.debian.org/src/gwama/
http://www.well.ox.ac.uk/GWAMA/ SCR_006624 Genome-Wide Association Meta Analysis 2026-02-14 02:01:21 175
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-02-14 02:01:19 149
SpliceTrap
 
Resource Report
Resource Website
10+ mentions
SpliceTrap (RRID:SCR_006728) SpliceTrap software resource A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Cold Spring Harbor Laboratory
PMID:21896509 biotools:splicetrap, OMICS_01292 https://bio.tools/splicetrap SCR_006728 2026-02-14 02:01:14 16
BEDTools
 
Resource Report
Resource Website
10000+ mentions
BEDTools (RRID:SCR_006646) BEDTools software resource A powerful toolset for genome arithmetic allowing one to address common genomics tasks such as finding feature overlaps and computing coverage. Bedtools allows one to intersect, merge, count, complement, and shuffle genomic intervals from multiple files in widely-used genomic file formats such as BAM, BED, GFF/GTF, VCF. While each individual tool is designed to do a relatively simple task (e.g., intersect two interval files), quite sophisticated analyses can be conducted by combining multiple bedtools operations on the UNIX command line. genomics, bed, sam, bam, overlap, sequencing, intersect, coverage, gff, vcf, bedgraph, interval, genome arithmetic, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Hydra
is related to: pybedtools
is required by: SL-quant
PMID:20110278
DOI:10.1093/bioinformatics/btq033
GNU General Public License, v2, Acknowledgement requested OMICS_01159, biotools:bedtools https://code.google.com/p/bedtools/
https://bio.tools/bedtools
https://sources.debian.org/src/bedtools/
SCR_006646 bedtools - a swiss army knife for genome arithmetic, bedtools: a flexible suite of utilities for comparing genomic features 2026-02-14 02:01:21 10394
Dictyostelium discoideum genome database
 
Resource Report
Resource Website
100+ mentions
Dictyostelium discoideum genome database (RRID:SCR_006643) dictyBase, dictyBase gene name, dictyBase REF, DictyBase biomaterial supply resource, organism supplier, material resource Model organism database for the social amoeba Dictyostelium discoideum that provides the biomedical research community with integrated, high quality data and tools for Dictyostelium discoideum and related species. dictyBase houses the complete genome sequence, ESTs, and the entire body of literature relevant to Dictyostelium. This information is curated to provide accurate gene models and functional annotations, with the goal of fully annotating the genome to provide a ''''reference genome'''' in the Amoebozoa clade. They highlight several new features in the present update: (i) new annotations; (ii) improved interface with web 2.0 functionality; (iii) the initial steps towards a genome portal for the Amoebozoa; (iv) ortholog display; and (v) the complete integration of the Dicty Stock Center with dictyBase. The Dicty Stock Center currently holds over 1500 strains targeting over 930 different genes. There are over 100 different distinct amoebozoan species. In addition, the collection contains nearly 600 plasmids and other materials such as antibodies and cDNA libraries. The strain collection includes: * strain catalog * natural isolates * MNNG chemical mutants * tester strains for parasexual genetics * auxotroph strains * null mutants * GFP-labeled strains for cell biology * plasmid catalog The Dicty Stock Center can accept Dictyostelium strains, plasmids, and other materials relevant for research using Dictyostelium such as antibodies and cDNA or genomic libraries. genome, sequence, est, literature, gene model, functional annotation, reference genome, gene, antibody, cdna, bacteria, dictyostelium discoideum, dictyostelium purpureum, dictyostelium fasciculatum, polysphondylium pallidium, bio.tools is used by: NIF Data Federation
is listed by: One Mind Biospecimen Bank Listing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: Textpresso
has parent organization: Northwestern University; Illinois; USA
has parent organization: Baylor University; Texas; USA
has parent organization: University of Cologne; Cologne; Germany
is parent organization of: Dictyostelium Discoideum Anatomy Ontology
is parent organization of: Dictyostelium Anatomy Ontology
is parent organization of: dictyBase - Teaching Tools Using Dictyostelium discoideum
NIGMS GM64426;
NIGMS GM087371;
NHGRI HG0022;
European Union
PMID:23172289
PMID:21087999
PMID:18974179
PMID:14681427
PMID:16381903
nif-0000-20974, biotools:dictybase, SCR_008149, nif-0000-02751, OMICS_03158 https://bio.tools/dictybase http://genome.imb-jena.de/dictyostelium/ SCR_006643 dictyBase gene name, dictyBase REF, Dicty, dictyBase, Dictyostelium discoideum 2026-02-14 02:01:10 306
Ribosomal Database Project
 
Resource Report
Resource Website
1000+ mentions
Ribosomal Database Project (RRID:SCR_006633) RDP data or information resource, database, resource A database which provides ribosome related data services to the scientific community, including online data analysis, rRNA derived phylogenetic trees, and aligned and annotated rRNA sequences. It specifically contains information on quality-controlled, aligned and annotated bacterial and archaean 16S rRNA sequences, fungal 28S rRNA sequences, and a suite of analysis tools for the scientific community. Most of the RDP tools are now available as open source packages for users to incorporate in their local workflow. microbiome, database, rrna gene sequence, rrna, ribosome, genome browser, high-throughput sequencing, bacteria, archaea, fungi, FASEB list is listed by: OMICtools
is listed by: Human Microbiome Project
has parent organization: Michigan State University; Michigan; USA
is parent organization of: RDPipeline
DOE DE-FG02-99ER62848;
DOE DE-SC0004601;
DOE DE-FC02-07ER64494;
NIEHS P42 ES004911;
NSF DBI-0328255;
USDA 2008-35107-04542;
NHLBI U01HL098961;
NIDDK UH3 DK083993
PMID:24288368
PMID:17586664
Open source r3d100012372, nif-0000-03404, OMICS_01513 https://doi.org/10.17616/R3C087 SCR_006633 Ribosomal Database Project 2026-02-14 02:01:20 1441
Ontology Lookup Service
 
Resource Report
Resource Website
10+ mentions
Ontology Lookup Service (RRID:SCR_006596) OLS web service, data or information resource, source code, data access protocol, software resource, database Interactive and programmatic interfaces to query, browse and navigate an increasing number of biomedical ontologies and controlled vocabularies. It provides a web service interface to query multiple ontologies from a single location with a unified output format. It can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The database can be queried to obtain information on a single term or to browse a complete ontology using AJAX. Auto-completion provides a user-friendly search mechanism. An AJAX-based ontology viewer is available to browse a complete ontology or subsets of it. A weekly MySQL database export file can be downloaded from the EBI public FTP directory. ontology, ontology or annotation browser, ontology or annotation search engine, gold standard lists: Cell Type Ontology
is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: OBO-Edit
is related to: OBO
has parent organization: European Bioinformatics Institute
BBSRC ;
iSPIDER ;
European Union FP6 Felics contract 021902 (RII3)
PMID:18467421
PMID:16507094
Apache License, v2, Acknowledgement requested OMICS_02275, nif-0000-10390, r3d100010413 https://doi.org/10.17616/R3GS9G http://www.ebi.ac.uk/ols SCR_006596 OLS - Ontology Lookup Service, Ontology Lookup Service (OLS) 2026-02-14 02:01:20 24
ALEXA-Seq
 
Resource Report
Resource Website
1+ mentions
ALEXA-Seq (RRID:SCR_006700) ALEXA-Seq software resource A method for using massively parallel paired-end transcriptome sequencing for ''alternative expression analysis''. is listed by: OMICtools OMICS_01328 SCR_006700 2026-02-14 02:01:11 6
Rice Genome Annotation
 
Resource Report
Resource Website
1000+ mentions
Rice Genome Annotation (RRID:SCR_006663) Osa1 data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Database and resource that provides sequence and annotation data for the rice genome. This website provides genome sequence from the Nipponbare subspecies of rice and annotation of the 12 rice chromosomes. All structural and functional annotation is viewable through our Rice Genome Browser which currently supports 75 tracks of annotation. Enhanced data access is available through web interfaces, FTP downloads and a Data Extractor tool developed in order to support discrete dataset downloads. Rice is a model species for the monocotyledonous plants and the cereals which are the greatest source of food for the world''s population. While rice genome sequence is available through multiple sequencing projects, high quality, uniform annotation is required in order for genome sequence data to be fully utilized by researchers. The existence of a common gene set and uniform annotation allows researchers within the rice community to work from a common resource so that their results can be more easily interpreted by other scientists. The objective of this project has always been to provide high quality annotation for the rice genome. They generated, refined and updated gene models for the estimated 40,000-60,000 total rice genes, provided standardized annotation for each model, linked each model to functional annotation including expression data, gene ontologies, and tagged lines. They have provided a resource to extend the annotation of the rice genome to other plant species by providing comparative alignments to other plant species. Analysis/Tools are available including: BLAST, Locus Name Search, Functional Term Search, Protein Domain Search, Anatomy Expression Viewer, Highly Expressed Genes rice, oryza sativa, maize, corn, zea mays, wheat, triticum aestivum, gene, genome, annotation, FASEB list is listed by: OMICtools
has parent organization: Michigan State University; Michigan; USA
NSF DBI-0321538;
NSF DBI-0834043
PMID:17145706 Acknowledgement requested OMICS_01563, nif-0000-31459 http://rice.tigr.org http://rice.plantbiology.msu.edu/pseudomolecules/info.shtml SCR_006663 Rice Genome Annotation Project, MSU Rice Genome Annotation Project Database and Resource 2026-02-14 02:01:13 1423
SpliceGrapher
 
Resource Report
Resource Website
10+ mentions
SpliceGrapher (RRID:SCR_006657) SpliceGrapher software resource Software that predicts alternative splicing patterns and produces splice graphs that capture in a single structure the ways a gene''s exons may be assembled. It enhances gene models using evidence from next-generation sequencing and EST alignments. is listed by: OMICtools
has parent organization: SourceForge
PMID:22293517 OMICS_01266 SCR_006657 2026-02-14 02:01:13 22
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2026-02-14 02:01:13 2
SoftSearch
 
Resource Report
Resource Website
1+ mentions
SoftSearch (RRID:SCR_006683) SoftSearch software resource A sensitive structural variant (SV) detection software tool for Illumina paired-end next-generation sequencing data. It simultaneously utilizes soft-clipping and read-pair strategies for detecting SVs to increase sensitivity. Soft clips are proxies for split-reads that indicate part of the read maps to the reference genome, but the other part is not localized at the same place (e.g. breakpoint spanning reads). Discordant read-pairs refer to a read and its mate, where the insert size is greater (or less than) the expected distribution of the dataset ? or ? where the mapping orientation of the reads is unexpected (e.g. both on the same strand). SoftSearch looks for areas with soft-clipping in the genome that have discordant read pairs supporting the anomaly. Once areas with both these conditions are identified, the read and mate information is extracted directly from the BAM file containing the discordant reads, obviating the need for time-consuming and error-prone complex alignment strategies. Only a small number of soft-masked bases discordant read-pairs are necessary to identify an SV, which on their own would not be sufficient to make an SV call, thus highlighting SoftSearch?s improved sensitivity. SoftSearch is well suited to be ?plugged in? to most sequence analysis workflows, since it requires standard file inputs, such as a BAM file using almost any aligner and a reference genome FASTA file. Because SoftSearch requires soft-masked bases, the only requirement is that the aligner must have this functionality, which is usually turned on by default by many standard aligners (e.g. BWA, Novoalign, etc). illumina, structural variant, next-generation sequencing, perl, academic is listed by: OMICtools
has parent organization: Google Code
GNU General Public License, v2 OMICS_00322 SCR_006683 SoftSearch - Detecting Structural Variations Using Split Reads and Discordant Read Pairs 2026-02-14 02:01:11 5
realSFS
 
Resource Report
Resource Website
10+ mentions
realSFS (RRID:SCR_002493) data analysis software, software resource, data processing software, software application Software program used to estimate allele frequency and SNP calling., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. allele frequency estimation, snp calling is listed by: OMICtools THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00071 SCR_002493 2026-02-14 02:00:25 26
ShotGun
 
Resource Report
Resource Website
10+ mentions
ShotGun (RRID:SCR_002529) sequence analysis software, data processing software, data analysis software, software application, software resource, simulation software Software for short read simulating in order to facilitate sequencing-based study designs. sequence based study design, short read stimulation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
PMID:23357921 Free, Available for download, Freely available biotools:abcd, OMICS_00255 https://bio.tools/abcd SCR_002529 ShotGun: a Flexible Short Read Simulator to Facilitate Sequencing-based Study Designs 2026-02-14 02:00:26 32
Gibbs Motif Sampler
 
Resource Report
Resource Website
1+ mentions
Gibbs Motif Sampler (RRID:SCR_002550) Gibbs Motif Sampler data analysis service, analysis service resource, production service resource, service resource, software resource Software to identify motifs, conserved regions, in DNA or protein sequences. dna, protein, motif, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:gibbs_motif_sampler, OMICS_00496 https://bio.tools/gibbs_motif_sampler SCR_002550 The Gibbs Motif Sampler 2026-02-14 02:00:17 2
MBASED
 
Resource Report
Resource Website
10+ mentions
MBASED (RRID:SCR_002584) software resource Software package containing functions for allele-specific gene expression (ASE) analysis using meta-analysis based allele-specific expression detection. software package, unix/linux, mac os x, windows, r, gene expression, sequencing, transcription is listed by: OMICtools
has parent organization: Bioconductor
PMID:25315065 Free, Available for download, Freely available OMICS_05502 http://www.bioconductor.org/packages/release/bioc/html/MBASED.html SCR_002584 Meta-analysis Based Allele-Specific Expression Detection, MBASED - Package containing functions for ASE analysis using Meta-analysis Based Allele-Specific Expression Detection 2026-02-14 02:00:17 17
pymzML
 
Resource Report
Resource Website
10+ mentions
pymzML (RRID:SCR_002500) software resource Python module to parse mzML data in Python based on cElementTree. It is an extension to Python that offers (i) an easy access to mass spectrometry (MS) data that allows the rapid development of tools, (ii) a very fast parser for mzML data and (iii) a set of functions to compare or handle spectra., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: mzML
has parent organization: University of Munster; North Rhine-Westphalia; Germany
PMID:22302572 Free, Available for download, Freely available biotools:pymzml, OMICS_03355 https://bio.tools/pymzml SCR_002500 2026-02-14 02:00:17 18
BioStar
 
Resource Report
Resource Website
50+ mentions
BioStar (RRID:SCR_002580) Biostar community building portal, portal, discussion, data or information resource, forum, narrative resource A question answer forum for scientists, focusing on methods in bioinformatics, computational genomics and biological data analysis. They welcome detailed and specific posts, written clearly and simply. bioinformatics, computational genomics, biological data analysis, data analysis, forum, question, answer is listed by: OMICtools
is related to: NeuroStars
NIH ;
Luma Education ;
NHGRI 5R25HG006243-02
PMID:22046109 Free, Freely available OMICS_01706, nlx_155982 SCR_002580 biostars.org 2026-02-14 02:00:25 84
discoSnp
 
Resource Report
Resource Website
1+ mentions
discoSnp (RRID:SCR_002612) sequence analysis software, data processing software, data analysis software, software application, software resource Software designed for discovering Single Nucleotide Polymorphism (SNP) from raw sets of reads obtained with Next Generation Sequencers (NGS). single nucleotide polymorphism, snp discovery, discover snp, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
SOFIPROTEOL under the FASO project PEAPOL ;
INRIA ANR-12-BS02-0008
PMID:25404127 Free, Freely available biotools:discosnp, OMICS_00267 https://bio.tools/discosnp
https://sources.debian.org/src/discosnp/
SCR_002612 DiscoSnp++, discovering Single Nucleotide Polymorphism, discovering Single Nucleotide Polymorphism (discoSNP) 2026-02-14 02:00:25 9
PeptideShaker
 
Resource Report
Resource Website
100+ mentions
PeptideShaker (RRID:SCR_002520) software resource Software providing a search engine independent platform for visualization of peptide and protein identification results from multiple search engines, currently supporting X!Tandem, MS-GF+, MS Amanda, OMSSA, MyriMatch, Comet, Tide, Mascot and mzIdentML. By combining the results from multiple search engines, while re-calculating PTM localization scores and redoing the protein inference, PeptideShaker attempts to give you the best possible understanding of your proteomics data. standalone software, proteomics, mass spectrometry, java, search engine, omssa, xtandem, mascot, ms-gf, msamanda, myrimatch, comet, tide is listed by: OMICtools
is related to: MS Amanda
has parent organization: Google Code
PMID:34709836 Free, Available for download, Freely available OMICS_03347 http://peptide-shaker.googlecode.com SCR_002520 2026-02-14 02:00:26 160

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