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https://github.com/compbiolabucf/TEDDY

Software package to impute gene expression for all participants, whether they have partially or completely missing gene expression.

Proper citation: Teddy study IA prediction (RRID:SCR_023303) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/community/profile/id/2228

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 13,2025.Core facility that provides access to isolated pancreatic islets from normal and diabetic models and performs islet functional analysis. The IPA Core also provides solutions for high-resolution whole slide imaging and access to image analysis tools for quantitative assessment of pancreatic islet morphology.

Proper citation: Vanderbilt Diabetes Research and Training Center Islet Procurement and Analysis Core (RRID:SCR_000896) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/mouse.html

Core which provides researchers with resources for performing metabolic studies in mice. It also provides services, innovative techniques, and helpful consultation to both experienced and novice investigators with regards to metabolic questions.

Proper citation: Penn Diabetes Research Center Mouse Phenotyping Physiology and Metabolism Core (RRID:SCR_000888) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/cellbio.html

Core that gives support including experimental design, islet isolation, and performance of and training in an expansive range of assays for physiological and morphometric assessment of pancreatic islet function and growth. It contributes to the basic and translational research activities of the Institute of Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine of the University of Pennsylvania. Its services include perform individual islet and single cell fluorescence imaging, respirometry with islet batches using a Seahorse Extracellular Flux Analyzer, perifusion coupled with respirometry, and closed respirometry experiments for our investigators.

Proper citation: University of Pennsylvania School of Medicine Penn Diabetes Research Center Pancreatic Islet Cell Biology Core Facility (RRID:SCR_008265) Copy   

•   Source: SciCrunch Registry

http://amp.pharm.mssm.edu/X2K/

Software tool to produce inferred networks of transcription factors, proteins, and kinases predicted to regulate the expression of the inputted gene list by combining transcription factor enrichment analysis, protein-protein interaction network expansion, with kinase enrichment analysis. It provides the results as tables and interactive vector graphic figures.

Proper citation: eXpression2Kinases (RRID:SCR_016307) Copy   

•   Source: SciCrunch Registry

https://psbweb05.psb.ugent.be/conet/microbialnetworks/spieceasi.php

Software R package estimates inverse covariance matrix from sequencing data.Statistical method for inference of microbial ecological networks from amplicon sequencing datasets.

Proper citation: Sparse Inverse Covariance Estimation for Ecological Association Inference (RRID:SCR_022646) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/community/profile/id/1133

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.

Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/microbiome

Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) Copy   

•   Source: SciCrunch Registry

https://einsteinmed.edu/centers/diabetes-research/human-Islet-and-adenovirus-core/

Core which provides methodologies, technology and infrastructure to support investigators in the use of human islets for research studies for the Einstein-Mount Sinai Diabetes Research Center. It isolates and prepares human and rodent islets/beta cells and cell lines for investigator-initiated research and generates specific viral vectors (adenovirus and lentivirus) for gene delivery of cDNAs and shRNAs of interest to beta cells and other islet cell types.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core Facility (RRID:SCR_015066) Copy   

•   Source: SciCrunch Registry

https://einsteinmed.edu/research/shared-facilities/barc/

Core provides information and tools for Einstein and Montefiore investigators from initial study planning stage through analysis and data output. Facility services include: mass spectrometry analysis, including stable isotopes, as well as research-grade determination of lipids, and metabolic markers for human subjects and animal model projects; High-throughput robotics for semi-automated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS); Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays; Research quality analysis of metabolites for human and animal samples using Olympus AU400 autoanalyzer; Advanced training in analytical chemistry.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility (RRID:SCR_015067) Copy   

•   Source: SciCrunch Registry

https://www.derc.cuimc.columbia.edu/services/translational-biomarker-analytical-core

Core makes available to Diabetes Research Center investigators variety of high quality radio-immunoassay, ELISA, and other analytical methods, and facilitates access of DRC investigators to measurement of small molecules by targeted and untargeted metabolomics/lipidomics with the Irving Institute Biomarkers Core. TBAC also provides consultations and services for in vivo methods to measure insulin secretion and sensitivity.

Proper citation: Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility (RRID:SCR_015077) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-research/diabetes.aspx?id=1566&ekmensel=15074e5e_4046_4048_28715_1

Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) Copy   

•   Source: SciCrunch Registry

https://einsteinmed.edu/centers/diabetes-research/biomedical-cores/animal-physiology/

Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) Copy   

•   Source: SciCrunch Registry

http://www.baderc.org/cores/transgenicCore.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice.

Proper citation: Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) Copy   

•   Source: SciCrunch Registry

http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/administrative.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that typically organizes a meeting with the investigator/user and relevant core directors to discuss the different services and tests that the Diabetes Research Center would recommend to the investigator. It also provides support letters for grant proposals submitted by investigators.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Administrative Core (RRID:SCR_015087) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-translational-research/latino-network/

Research network dedicated to supporting translation research in diabetes prevention and control. The core has a strong emphasis on sociocultural adaption for Latinos in the U.S and can provide expertise in Latino biopsychosocial research.

Proper citation: New York Regional Center for Diabetes Translation Research Latino Network for Diabetes Translational Research (RRID:SCR_015189) Copy   

•   Source: SciCrunch Registry

http://diabetesresearch.med.umich.edu/Core_MCDTR_Methods.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Research core that works to assist investigators in designing studies, collecting data, and analyzing data to examine questions related to the causes, prevention, and control of diabetes, its complications, and comorbidities.

Proper citation: Michigan Center for Diabetes Translational Research Methods and Measurements Core (RRID:SCR_015188) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/liver-research/research-cores/special-animals-core.aspx

Core that provides resources, technologies and scientific expertise to advance translational applications of animal and human liver cells. It also provides bred animals for research, isolation and culture of animal and human liver cells, as well as provision of cell culture additives and materials.

Proper citation: Marion Bessin Liver Research Center Animal Models Stem Cells and Cell Therapy (RRID:SCR_015181) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/liver-research/research-cores/imaging-and-cell-structure-core.aspx

Core that supports and assists with use of specialized instrumentation, including laser scanning confocal microscopy, deconvolution microscopy, multi-photon microscopy, cryo-electron microscopy (cryo-EM) and correlative light electron microscopy (CLEM). It also provides expertise in and assistance with specialized imaging techniques such as correlative microscopy, vesicle tracking, volumetric measurements, ultrastructural sample preparation, super resolution fluorescence microscopy (STORM/SIM), Fluorescence Recovery After Photobleaching (FRAP), Fluorescence Resonance Energy Transfer (FRET) and Total Internal Reflection Microscopy (TIRF).

Proper citation: Marion Bessin Liver Research Center Imaging and Cell Structure (RRID:SCR_015182) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-translational-research/timc/

Core facility that supports research that addresses the prevention and control of diabetes using a social-ecological approach to address the dynamic interrelations of biological, psychological and social factor at a personal and environmental level.

Proper citation: New York Regional Center for Diabetes Translation Research Translational Intervention Methodology Core (RRID:SCR_015180) Copy   

•   Source: SciCrunch Registry