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http://drc.ucsf.edu/mouse-genetics-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 5,2024. Core that provides a shared resource for the establishment of mutant mouse models for DRC research. It coordinates DRC members with contacts to a number of UCSF-wide facilities for knock-out/knock-in and transgenic mouse generation.
Proper citation: University of California San Francisco Diabetes Research Center Mouse Genetics Core Facility (RRID:SCR_015109) Copy
http://www.uab.edu/shp/drc/administrative-core-links
Core responsible for the scientific, education/enrichment, and fiscal operations of the DRC. Their goal is to assure the growing vitality of an intellectual community and a highly productive research program in diabetes by effective deployment of DRC resources for the benefit of our investigators, patients, and trainees.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Administrative Core Facility (RRID:SCR_015108) Copy
http://www.uab.edu/shp/drc/bioanalytical-redox-biology-core-barb-links
Core which promotes redox biology in diabetes-related research. It promotes research in areas common to the metabolic and vascular aspects of diabetes and cardiovascular disease. The core provides services in mitochondrial damage, function, proteomics, and oxidative stress assessment support for investigators carrying out diabetes mellitus (DM) and cardiometabolic disease (CMD) research at UAB.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Bioanalytical REDOX Biology Core Facility (RRID:SCR_015113) Copy
https://www.derc.cuimc.columbia.edu/services/translational-biomarker-analytical-core
Core makes available to Diabetes Research Center investigators variety of high quality radio-immunoassay, ELISA, and other analytical methods, and facilitates access of DRC investigators to measurement of small molecules by targeted and untargeted metabolomics/lipidomics with the Irving Institute Biomarkers Core. TBAC also provides consultations and services for in vivo methods to measure insulin secretion and sensitivity.
Proper citation: Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility (RRID:SCR_015077) Copy
http://www.uab.edu/shp/drc/human-physiology-core-links
Core which incorporates and combines expertise and technology for assessment of hormones and other analytes in both humans and animal models; body composition and fat distribution; insulin sensitivity and substrate metabolism; energy expenditure; and cardiovascular function.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Human Physiology Core Facility (RRID:SCR_015111) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/genomics.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that provides services in genotyping, sequencing, biobanks, and genetic epidemiology. It also offers access to the Amish exome variant database, basic molecular services, and viral vector construction and development.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Molecular and Translational Genomics Core (RRID:SCR_015116) Copy
http://diabetesresearch.med.umich.edu/Core_MDRC_OMICS.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that supports the use of the OMICS technologies by MDRC members (specifically on projects relevant to diabetes and related endocrine and metabolic disorders, including their complications) by supporting pilot studies that utilize these technologies.
Proper citation: Michigan Diabetes Research Center OMICS Core (RRID:SCR_015117) Copy
Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) Copy
https://einsteinmed.edu/centers/diabetes-research/biomedical-cores/animal-physiology/
Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) Copy
http://www.baderc.org/cores/transgenicCore.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice.
Proper citation: Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) Copy
Provides MDRC researchers with expert consultation, training and support for routine and advanced microscopy and image analysis techniques. Services include Consultation and Advice on Microscopy and Immunohistochemistry, Cryosection Service, Confocal Microscopy, Image Analysis, Widefield Light Microscopy,Live Cell Microscopy,Training and Education.
Proper citation: Michigan Diabetes Research Center Microscopy and Image Analysis Core Facility (RRID:SCR_015118) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/integrated-physiology.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core consisting of several subcores: Ligand Assay and Biomarker Subcore (offers services in Multiplex Assay Detection Systems, Comprehensive Laboratory Animal Monitoring System (CLAMS), and Body Composition), Rodent Physiology and Behavioral Analysis Subcore, and Glucose Metabolism Analysis Subcore (provides services in Dynamic Physiologic Testing).
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Integrated Physiology Core (RRID:SCR_015088) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/administrative.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that typically organizes a meeting with the investigator/user and relevant core directors to discuss the different services and tests that the Diabetes Research Center would recommend to the investigator. It also provides support letters for grant proposals submitted by investigators.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Administrative Core (RRID:SCR_015087) Copy
https://diabetescenters.org/cores/ucsd-ucla-human-genetics-core
Core provides services such as assistance in the development and successful completion of well-designed genetic studies, establishment and storage of EBV-transformed lymphoblastoid cell lines (LCLs), as well as PAXgene tubes, and specialized (e.g., the exome chip) single nucleotide polymorphism (SNP) testing, candidate gene sequencing, whole exome sequencing (WES), whole genome sequencing (WGS), and large-scale gene methylation analysis.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Human Genetics Core Facility (RRID:SCR_015099) Copy
https://joslinresearch.org/drc-cores/Enrichment-Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Six component core which facilitates the exchange of research information and discussions among investigators, fellows and students within the Joslin Diabetes Center, as well as between Joslin Staff and outside researchers with similar interests.
Proper citation: Joslin Diabetes Center Enrichment Core (RRID:SCR_015094) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/gene-editing.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in Gene Editing Expertise Using CRISPR/CAS9, Conventional Transgenic Mouse Generation, Conventional Knockout, Knock-In Mouse Generation, and Cryopereservation of Sperm, Oocytes and Embryos.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Gene Editing Core (RRID:SCR_015091) Copy
Core that offers support for data-driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.
Proper citation: Joslin Diabetes Center Bioinformatics and Biostatistics Core (RRID:SCR_015092) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8, 2024. Core with main goal to steer investigators through introductory discovery lipidomics and proteomics experiments toward statistically powered, targeted experiments aimed at measuring biological pathways relevant to diabetes and metabolism.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Targeted Pathway Analysis Core Facility (RRID:SCR_015098) Copy
https://diabetescenters.org/cores/ucsd-ucla-transgenic-and-knockout-mouse-core
Core that provides and produces transgenic mice. Services and methodologies include pronuclear microinjection and blastocyst microinjection for creation of new mouse cell lines as well as archival services like embryo and sperm freezing.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Transgenic and Knockout Mouse Core Facility (RRID:SCR_015096) Copy
http://www.cure.med.ucla.edu/cores/animal-models
Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.
Proper citation: CURE - Digestive Diseases Research Center Animal Models Core (RRID:SCR_015217) Copy
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