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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Center that includes over seventy investigators engaged in basic and translational research in diabetes and related metabolic disorders, and their complications. It contains four Research Cores that serve for innovative and translational research.
Proper citation: Indiana Diabetes Research Center (RRID:SCR_015080) Copy
Network helps to organize and support collaborative research related to loss of functional beta cell mass in Type 1 Diabetes (T1D). Project consists of four independent research initiatives: Consortium on Beta Cell Death and Survival (CBDS), Consortium on Human Islet Biomimetics (CHIB), Consortium on Modeling Autoimmune Interactions (CMAI), Consortium on Targeting and Regeneration (CTAR), and Human Pancreas Analysis Program (HPAP).
Proper citation: Human Islet Research Network (HIRN) (RRID:SCR_014393) Copy
https://github.com/compbiolabucf/APA-Scan
Software Python tool for detection and visualization of annotated and potential alternative polyadenylation events in downstream 3'-UTR of gene among two different biological conditions. Used for detection and visualization of 3'-UTR alternative polyadenylation with RNA-seq and 3'-end-seq data.
Proper citation: APA-Scan (RRID:SCR_022974) Copy
https://generanger.maayanlab.cloud/gene/A2M?database=ARCHS4
Web server application that provides access to processed data about expression of human genes and proteins across human cell types, tissues, and cell lines from several atlases. Used to explore single gene expression across tissues and cell types.
Proper citation: GeneRanger (RRID:SCR_023622) Copy
https://targetranger.maayanlab.cloud/
Web server application that identifies targets from user inputted RNA-seq samples collected from cells we wish to target. By comparing inputted samples with processed RNA-seq and proteomics data from several atlases, TargetRanger identifies genes that are highly expressed in target cells while lowly expressed across normal human cell types, tissues, and cell lines.
Proper citation: TargetRanger (RRID:SCR_023621) Copy
http://www.med.upenn.edu/molecular/core_culture.shtml
Core facility that maintains a centralized repository of cells and reagents pertinent to digestive, liver and pancreatic disease research. It also provides training for labs in new cell culture (2D and 3D) techniques.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Cell Culture Core (RRID:SCR_015621) Copy
https://assess-aki.hmc.psu.edu/
A study which recruits patients with and without an episode of acute kidney injury during a hospitalization, and follows them longitudinally for major cardiac, renal and mortality events. An important aspect of the study is the prospective evaluation of potential biomarkers for renal and cardiac outcomes.
Proper citation: Assessment Serial Evaluation and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) (RRID:SCR_014386) Copy
Center whose goal is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.
Proper citation: UCSF Liver Center (RRID:SCR_015595) Copy
A study to determine whether vitamin D supplementation is safe and effective in delaying the onset of type 2 diabetes in people at risk for the disease and to gain a better understanding of how vitamin D affects glucose metabolism.
Proper citation: Vitamin D to Prevent Type 2 Diabetes (D2d) (RRID:SCR_014382) Copy
http://livercenter.ucsf.edu/cell-biology-core
Core whose purpose is providing primary and immortalized liver cells for experimental use as well as other material such as human liver cells, primary hepatocytes, and immortalized cell lines.
Proper citation: UCSF Liver Center Cell Biology Core (RRID:SCR_015600) Copy
http://www.uchicagoddrcc.org/research-cores/integrated-translational-research-core
Core that serves as both a central repository for all the samples and data shared by the other cores and a catalyst for interdisciplinary research.
Proper citation: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core (RRID:SCR_015606) Copy
Encyclopedia of white and brown adipocyte secretome in mouse models and humans as key prerequisite to elucidating role of these mediators in normal physiology and disease.
Proper citation: Secrepedia (RRID:SCR_022590) Copy
https://labnodes.vanderbilt.edu/community/profile/id/1133
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.
Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy
Provides services including sequencing library preparation and sequencing on Illumina MiSeq and NovaSeq 6000 platforms. Supports single cell sequencing on 10X Genomics Chromium Controller. Provides Illumina Infinium Beadchips, which includes variety of whole genome genotyping arrays as well as Infinium MethylationEPIC BeadChip.
Proper citation: University of California at San Diego Institute for Genomic Medicine Genomics Center Core Facilitiy (RRID:SCR_022740) Copy
https://ncdiabetesresearch.org/metabolomics
Provides platform for quantitative targeted metabolic profiling by MS/MS and GC/MS, supported by library of stable isotope labeled standards as well as extensive scientific expertise to help researchers navigate core resources and use of services.
Proper citation: North Carolina Diabetes Research Center Metabolomics Core Facility (RRID:SCR_022909) Copy
https://ncdiabetesresearch.org/genomics
Provides resources and expertise in genomics and mass spectrometry at Wake Forest Center for Precision Medicine. Provides unique access to instrumentation and analytical expertise to NCDRC faculty in support of advancement of diabetes research.Overlooks the use of existing resources at NCDRC partner institutions (UNC, NC A&T, and Duke University) to coordinate work and data analysis with Metabolomics Core to provide omics analyses.Offers analytic services, expertise, and tools to integrate data to better understand interactive systems at play in disease processes.
Proper citation: North Carolina Diabetes Research Center Genomics and Proteomics Core Facility (RRID:SCR_022907) Copy
Core facilitates access and usage of tissues and services to meet specialized needs of diabetes research community to expedite and catalyze innovative diabetes research at UC AMC. Provides resources to assist DRC investigators with acquisition and processing of rodent and human tissue, and specialized cell lines that are broadly required for diabetes research.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Tissue Procurement and Processing Core Facility (RRID:SCR_022904) Copy
http://www.med.unc.edu/microbiome
Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) Copy
https://einsteinmed.edu/centers/diabetes-research/human-Islet-and-adenovirus-core/
Core which provides methodologies, technology and infrastructure to support investigators in the use of human islets for research studies for the Einstein-Mount Sinai Diabetes Research Center. It isolates and prepares human and rodent islets/beta cells and cell lines for investigator-initiated research and generates specific viral vectors (adenovirus and lentivirus) for gene delivery of cDNAs and shRNAs of interest to beta cells and other islet cell types.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core Facility (RRID:SCR_015066) Copy
https://einsteinmed.edu/research/shared-facilities/barc/
Core provides information and tools for Einstein and Montefiore investigators from initial study planning stage through analysis and data output. Facility services include: mass spectrometry analysis, including stable isotopes, as well as research-grade determination of lipids, and metabolic markers for human subjects and animal model projects; High-throughput robotics for semi-automated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS); Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays; Research quality analysis of metabolites for human and animal samples using Olympus AU400 autoanalyzer; Advanced training in analytical chemistry.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility (RRID:SCR_015067) Copy
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