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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/2.12/bioc/html/DNAcopy.html
Software that segments DNA copy number data using circular binary segmentation to detect regions with abnormal copy number.
Proper citation: DNAcopy (RRID:SCR_012560) Copy
http://www.bioconductor.org/packages/release/bioc/html/ExiMiR.html
R functions for the normalization of Exiqon miRNA array data.
Proper citation: ExiMiR (RRID:SCR_012753) Copy
http://sourceforge.net/projects/cnv/
Software for a web-enabled platform for analyzing genome variation such as copy number variation (CNV).
Proper citation: CNV Workshop (RRID:SCR_012635) Copy
http://www.bioconductor.org/packages/release/bioc/html/motifRG.html
Software tools for discriminative motif discovery using regression methods.
Proper citation: motifRG (RRID:SCR_012602) Copy
http://www.bioconductor.org/packages/release/bioc/html/MiRaGE.html
Software package that contains functions for inference of target gene regulation by miRNA, based on only target gene expression profile.
Proper citation: MiRaGE (RRID:SCR_012738) Copy
http://www.bioconductor.org/packages/release/bioc/html/CexoR.html
Software for strand specific peak-pair calling in ChIP-exo replicates.
Proper citation: CexoR (RRID:SCR_012769) Copy
http://tare.medisin.ntnu.no/motiflab/
Software for a general workbench for analyzing regulatory sequence regions and discovering transcription factor binding sites and cis-regulatory modules.
Proper citation: MotifLab (RRID:SCR_012649) Copy
http://www.bioconductor.org/packages/release/bioc/html/tRanslatome.html
Detection of differentially expressed genes (DEGs) from the comparison of two biological conditions among different levels of gene expression, using several statistical methods: Rank Product, t-test, SAM, Limma, ANOTA, DESeq, edgeR.
Proper citation: tRanslatome (RRID:SCR_012810) Copy
https://github.com/bedops/bedops
A suite of tools to address common questions raised in genomic studies - mostly with regard to overlap and proximity relationships between data sets.
Proper citation: BEDOPS (RRID:SCR_012865) Copy
http://bioinf.wehi.edu.au/featureCounts/
A read summarization program, which counts mapped reads for the genomic features such as genes and exons.
Proper citation: featureCounts (RRID:SCR_012919) Copy
http://www.bioconductor.org/packages/release/bioc/html/BicARE.html
Biclustering Analysis and Results Exploration.
Proper citation: BicARE (RRID:SCR_012881) Copy
http://www.bioconductor.org/packages/release/bioc/html/charm.html
Function for differentially methylated regions (DMR) detection that is a part of the charm package in R/Bioconductor.
Proper citation: dmrFinder (RRID:SCR_012853) Copy
http://www.bioconductor.org/packages/release/bioc/html/ChIPpeakAnno.html
Software package that includes functions to retrieve the sequences around the peak, obtain enriched Gene Ontology terms, find the nearest gene, exon, miRNA or custom features such as most conserved elements.
Proper citation: ChIPpeakAnno (RRID:SCR_012828) Copy
http://www.bioconductor.org/packages/release/bioc/html/inSilicoMerging.html
Collection of techniques to remove inter-study bias when combining gene expression data originating from different studies.
Proper citation: inSilicoMerging (RRID:SCR_012829) Copy
http://bioconductor.org/packages/release/bioc/html/DEXSeq.html
Software package focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.
Proper citation: DEXSeq (RRID:SCR_012823) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/snapCGH.html
Software providing methods for segmenting, normalising and processing aCGH data; including plotting functions for visualising raw and segmented data for individual and multiple arrays.
Proper citation: snapCGH (RRID:SCR_012947) Copy
http://www.fda.gov/ScienceResearch/BioinformaticsTools/Arraytrack/default.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 23,2023. Provides an integrated solution for managing, analyzing, and interpreting microarray gene expression data.
Proper citation: ArrayTrack (RRID:SCR_012839) Copy
http://www.bioconductor.org/packages/release/bioc/html/miRNApath.html
Software package that provides pathway enrichment techniques for miRNA expression data.
Proper citation: miRNApath (RRID:SCR_012833) Copy
Software tool that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Currently over 56% of human genomic sequence is identified and masked by the program. Sequence comparisons in RepeatMasker are performed by one of several popular search engines including nhmmer, cross_match, ABBlast/WUBlast, RMBlast and Decypher. RepeatMasker makes use of curated libraries of repeats and currently supports Dfam ( profile HMM library ) and RepBase ( consensus sequence library ).
Proper citation: RepeatMasker (RRID:SCR_012954) Copy
http://www.bioconductor.org/packages/release/bioc/html/sva.html
Contains functions for removing batch effects and other unwanted variation in high-throughput experiment.
Proper citation: sva package (RRID:SCR_012836) Copy
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