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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SALT
 
Resource Report
Resource Website
1000+ mentions
SALT (RRID:SCR_003187) SALT software resource Software that can accurately and sensitivity classify short reads of next-generation sequencing (NGS) into protein domain families. It is based on profile HMM and a supervised graph contribution algorithm. Compared to existing tools, it has high sensitivity and specificity in classifying short reads into their native domain families. next-generation sequencing, protein, protein domain, short read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23782615 Free, Available for download, Freely available OMICS_01565, biotools:salt https://bio.tools/salt SCR_003187 SALT - Protein domain classifier 2026-02-14 02:00:30 1294
XORRO
 
Resource Report
Resource Website
1+ mentions
XORRO (RRID:SCR_003181) XORRO software resource Efficient paired-read overlap software program for use with Illumina sequencing. illumina, next-generation sequencing is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_01569 SCR_003181 XORRO: Rapid Paired-End Read Overlapper 2026-02-14 02:00:41 1
NovelSeq
 
Resource Report
Resource Website
NovelSeq (RRID:SCR_003136) NovelSeq software resource Software pipeline to detect novel sequence insertions using high throughput paired-end whole genome sequencing data. sequence, insertion, genome sequencing, genome, next-generation sequencing, illumina, unix, linux, c, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:20385726 Free, Available for download, Freely available biotools:novelseq, nlx_156791, OMICS_02164 https://mybiosoftware.com/novelseq-1-0-2-sequence-insertions-detection.html#google_vignette SCR_003136 NovelSeq: Novel Sequence Insertion Detection 2026-02-14 02:00:30 0
mrCaNaVaR
 
Resource Report
Resource Website
10+ mentions
mrCaNaVaR (RRID:SCR_003135) mrCaNaVaR software resource Copy number caller that analyzes the whole-genome next-generation sequence mapping read depth to discover large segmental duplications and deletions. It also has the capability of predicting absolute copy numbers of genomic intervals. genome, next-generation sequence, duplication, deletion, copy number variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
Free, Freely available OMICS_02138, nlx_156790, biotools:mrcanavar https://bio.tools/mrcanavar SCR_003135 mrCaNaVaR - micro-read Copy Number Variant Regions, micro-read Copy Number Variant Regions 2026-02-14 02:00:40 14
SaskPrimerFS
 
Resource Report
Resource Website
SaskPrimerFS (RRID:SCR_003159) SaskPrimerFS software resource Software pipeline for designing gene family specific PCR primers. It infers intronic regions of a target species and design for them by utilizing DNA sequence information from a reference organism. gene family, pcr primer, pcr, primer, dna sequence, command-line, perl is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_02335 SCR_003159 2026-02-14 02:00:41 0
Pipeliner
 
Resource Report
Resource Website
1+ mentions
Pipeliner (RRID:SCR_003171) software resource Software for evaluating the performance of bioinformatics pipelines for Next Generation re-Sequencing. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24890372 Free, Available for download, Freely available OMICS_04844, biotools:pipeliner https://bio.tools/pipeliner SCR_003171 2026-02-14 02:00:30 6
ALDEx2
 
Resource Report
Resource Website
500+ mentions
ALDEx2 (RRID:SCR_003364) software resource Software tool to examine compositional high-throughput sequence data with Welch's t-test. A differential relative count abundance analysis for the comparison of two conditions. For example, single-organism and meta-rna-seq high-throughput sequencing assays, or of selected and unselected values from in-vitro sequence selections. Uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected Benjamini-Hochberg false discovery rate given the biological and sampling variation using several parametric and non-parametric tests. Can to glm and Kruskal-Wallace tests on one-way ANOVA style designs. standalone software, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: aldex
has parent organization: Western University; Ontario; Canada
PMID:24910773 Free, Available for download, Freely available biotools:aldex2, OMICS_04634 https://bio.tools/aldex2 SCR_003364 2026-02-14 02:00:32 529
RCircos
 
Resource Report
Resource Website
100+ mentions
RCircos (RRID:SCR_003310) software resource Software package that provides a simple and flexible way to generate Circos 2D track plot images for genomic data visualization. The types of plots include: heatmap, histogram, lines, scatterplot, tiles and plot items for further decorations include connector, link (lines and ribbons), and text (gene) label. All functions require only R graphics package that comes with R base installation. standalone software, unix/linux, mac os x, windows, r is listed by: OMICtools
is related to: shinyCircoss
has parent organization: CRAN
has parent organization: Bitbucket
PMID:23937229 Free, Available for download, Freely available OMICS_04661 https://bitbucket.org/henryhzhang/rcircos/ SCR_003310 RCircos: Circos 2D Track Plot 2026-02-14 02:00:25 245
JCVI Primer Designer
 
Resource Report
Resource Website
1+ mentions
JCVI Primer Designer (RRID:SCR_003275) JCVI Primer Designer software resource High throughput PCR primer design software. Target regions defined through a rich set of descriptors, such as Ensembl accessions and arbitrary genomic coordinates, may be specified. Primer pairs are then selected computationally to produce a minimal amplicon set capable of tiling across the specified target regions. As part of the tiling process, primer pairs are computationally screened to meet the criteria for success with one of two PCR amplification protocols. perl, command-line, pcr primer design, pcr, primer, high throughput sequencing is listed by: OMICtools
has parent organization: SourceForge
PMID:18405373 Free, Available for download, Freely available OMICS_02330 SCR_003275 2026-02-14 02:00:44 1
ddCt
 
Resource Report
Resource Website
100+ mentions
ddCt (RRID:SCR_003396) ddCt software resource Software package providing an approximation method to determine relative gene expression with quantitative real-time PCR (qRT-PCR) experiments. It requires no standard curve for each primer-target pair, therefore reducing the working load and yet returning accurate enough results as long as the assumptions of the amplification efficiency hold. The package implements a pipeline to collect, analyze and visualize qRT-PCR results, for example those from TaqMan SDM software, mainly using the ddCt method. The pipeline can be either invoked by a script in command-line or through the API consisting of S4-Classes, methods and functions. differential expression, gene expression, microtitre plate assay, q-pcr is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02312 SCR_003396 Delta-Delta-Ct 2026-02-14 02:00:48 321
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/
https://bio.tools/ggbio
SCR_003313 ggbio - Visualization tools for genomic data 2026-02-14 02:00:45 14
NormFinder
 
Resource Report
Resource Website
1000+ mentions
NormFinder (RRID:SCR_003387) NormFinder software resource Software for identifying the optimal normalization gene among a set of candidates. It ranks the set of candidate normalization genes according to their expression stability in a given sample set and given experimental design. It can analyze expression data obtained through any quantitative method e.g. real time RT-PCR and microarray based expression analysis. NormFinder.xla adds the NormFinder functionality directly to Excel. A version for R is also available. normalization, gene is used by: RefFinder
is listed by: OMICtools
PMID:15289330 Free, Available for download, Freely available OMICS_02317 https://www.moma.dk/software/normfinder SCR_003387 NormFinder software - Determine the optimal normalization gene 2026-02-14 02:00:47 2419
PrimerSeq
 
Resource Report
Resource Website
1+ mentions
PrimerSeq (RRID:SCR_003295) PrimerSeq software resource Software that designs RT-PCR primers that evaluate alternative splicing events by incorporating RNA-Seq data. It is particularly advantageous for designing a large number of primers for validating alternative splicing events found in RNA-Seq data. It incorporates RNA-Seq data in the design process to weight exons by their read counts. Essentially, the RNA-Seq data allows primers to be placed using actually expressed transcripts. This could be for a particular cell line or experimental condition, rather than using annotations that incorporate transcripts that are not expressed for the data. Alternatively, you can design primers that are always on constitutive exons. PrimerSeq does not limit the use of gene annotations and can be used for a wide array of species. primer, rna-seq, rt-pcr, windows, mac os x, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24747190 Free, Available for download, Freely available biotools:primerseq, OMICS_02328 https://bio.tools/primerseq SCR_003295 Primer Seek in RNA-Seq 2026-02-14 02:00:25 7
OmicCircos
 
Resource Report
Resource Website
50+ mentions
OmicCircos (RRID:SCR_003292) software resource An R software application and package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. standalone software, unix/linux, mac os x, windows, r, annotation, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24526832 Free, Available for download, Freely available OMICS_04659 http://www.bioconductor.org/packages/release/bioc/html/OmicCircos.html SCR_003292 OmicCircos: High-quality circular visualization of omic data 2026-02-14 02:00:31 79
MIPgen
 
Resource Report
Resource Website
10+ mentions
MIPgen (RRID:SCR_003325) software resource Software for a fast, simple way to generate designs for MIP assays targeting hundreds or thousands of genomic loci in parallel. Packaged with MIPgen are scripts that aid in visualization of MIP designs and processing of MIP sequence reads to SAM files that can then be passed through any standard variant calling pipeline. standalone software, c++, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:24867941 Free, Available for download, Freely available OMICS_04657, biotools:mipgen https://github.com/shendurelab/MIPGEN
https://bio.tools/mipgen
SCR_003325 MIPgen - One stop MIP design and analysis 2026-02-14 02:00:46 48
PoPoolation2
 
Resource Report
Resource Website
100+ mentions
PoPoolation2 (RRID:SCR_003284) software resource Software to compare allele frequencies for SNPs between two or more populations and to identify significant differences. PoPoolation2 requires next generation sequencing data of pooled genomic DNA (Pool-Seq). It may be used for measuring differentiation between populations, for genome wide association studies and for experimental evolution., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, next generation sequencing, population genetics, population genomics, statistics, toolkit, population is listed by: OMICtools
has parent organization: Google Code
PMID:22025480 Free, Available for download, Freely available OMICS_05824 SCR_003284 2026-02-14 02:00:44 242
DAFGA
 
Resource Report
Resource Website
1+ mentions
DAFGA (RRID:SCR_003319) software resource A python script package which estimates the evolutionary rate of a particular functional gene in a standardized manner by relating its sequence divergence to that of the 16S rRNA gene. It provides gene-specific parameter sets for OTU clustering and taxonomic assignment at desired rank, and it can be implemented into the diversity measurements offered by QIIME or Mothur. standalone software, python is listed by: OMICtools PMID:24939150 Free, Available for download, Freely available OMICS_04654 SCR_003319 DAFGA: Diversity Analysis of Functional Gene Amplicons, Diversity analysis of Functional Gene Amplicons 2026-02-14 02:00:46 1
Snakemake
 
Resource Report
Resource Website
100+ mentions
Snakemake (RRID:SCR_003475) Snakemake software resource A Python based language and execution environment for make-like workflows. The system supports the use of automatically inferred multiple named wildcards (or variables) in input and output filenames. python, workflow, bio.tools is used by: RiboSnake
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22908215
DOI:10.1093/bioinformatics/bts480
Free, Available for download, Freely available OMICS_02299, biotools:snakemake https://snakemake.github.io/ SCR_003475 snakemake - A Python based language and execution environment for make-like workflows 2026-02-14 02:00:49 393
PheWAS R Package
 
Resource Report
Resource Website
1+ mentions
PheWAS R Package (RRID:SCR_003512) software resource Software package contains methods for performing Phenome-Wide Association Study. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Vanderbilt University; Tennessee; USA
PMID:20335276 Free OMICS_00242, biotools:phewas https://bio.tools/phewas SCR_003512 Phenome-Wide Association Study 2026-02-14 02:00:28 6
NGSANE
 
Resource Report
Resource Website
10+ mentions
NGSANE (RRID:SCR_003478) NGSANE software resource Software providing a Linux-based High Performance Computing (HPC) enabled framework for high-throughput data analysis that minimizes overhead for set up and processing of new projects yet maintains full flexibility of custom scripting when processing raw sequence data. next generation sequencing is listed by: OMICtools PMID:24470576 BSD License, v3 OMICS_02298 SCR_003478 Next Generation Sequencing ANalysis for Enterprises 2026-02-14 02:00:27 10

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