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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Research on microbial agents, which cause lethal diseases in humans and for which effective drugs or preventive vaccines are not available, must be conducted by well-trained investigators in specially built, well-maintained laboratories. Core provides the triad of service, research and development, and education and training.
Proper citation: University of Hawaii at Manoa ABSL3/BSL3 Biocontaminant Core Facility (RRID:SCR_022878) Copy
https://med.virginia.edu/biorepository-and-tissue-research-facility/
Core is involved in procurement and processing of human tissue and other biospecimens for basic, translational, and clinical research.Provides laboratory support services for clinical trials, tissue samples from remnant surgical resection and autopsy specimens linked to clinicopathologic data while maintaining patient confidentiality. Provides biorepository of human specimens.Offers advanced histology services including multi color immunohistochemistry, in situ hybridization, tissue microarrays, slide scanning, computerized image analysis, NanoString spatial profiling.
Proper citation: University of Virginia School of Medicine Biorepository and Tissue Research Core Facility (RRID:SCR_022971) Copy
https://www.janelia.org/support-team/quantitative-genomics
Provides services to anything related to genomic analysis, such as RNAseq, genome sequencing, ATACseq etc, from experiment design all the way down to data analysis.Provides expert services for cell isolation, transcriptome and epigenetic profiling, and de novo genome assembly using next generation sequencing platforms from Illumina.
Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Quantitative Genomics Core Facility (RRID:SCR_022694) Copy
https://nyumc.ilab.agilent.com/sc/5998/research_software_engineering_core
Core is resource launched by NYU Langone, based in Information Technology department in close collaboration with NYU Grossman School of Medicine.Used to design, develop, optimize, and customize software to accelerate research. Requires iLab log in.
Proper citation: New York University Langone Medical Center Research Software Engineering Core Facility (RRID:SCR_023022) Copy
Offers services to researchers looking for collaborators or contractors for their educational or training projects.Offers development tools and hosting services to educators creating their own online training resources.
Proper citation: Texas A and M University Center for Educational Technologies Core Facility (RRID:SCR_022691) Copy
https://www.chumontreal.qc.ca/crchum/plateformes-services/imagerie-cellulaire
Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.
Proper citation: University of Montreal CRCHUM Cell Imaging Core Facility (RRID:SCR_022726) Copy
Offers services in fragment based screening and drug discovery, characterization and QC of biologics and biosimilar drugs, metabolomics, protein NMR, small molecule NMR, and NMR of natural products. Offers 400-700MHz systems, many with cryogenic probes.
Proper citation: Harvard Medical School Biomolecular Nuclear Magnetic Resonance Core Facility (RRID:SCR_022967) Copy
https://drexel.edu/core-facilities/facilities/cell-imaging/
Facility housed in purpose built imaging suites in Papadakis Integrated Sciences Building and in Bossone Research Center. Serves light microscopy needs of Drexel researchers and supports teaching missions of Biology and Biomedical Engineering curricula and provides service to users from local biotech companies.Provides facility, expertise, and education in advanced quantitative light microscopy.
Proper citation: Drexel University Cell Imaging Center Core Facility (RRID:SCR_022689) Copy
https://research.utexas.edu/cbrs/cores/cbb/
Provides support for students, postdoctoral fellows, and faculty interested in the use of computational approaches to solving biological problems. Our goal is to lower as much as possible the threshold to enter the -omics area of the life sciences.
Proper citation: University of Texas at Austin Computational Biology and Bioinformatics Core Facility (RRID:SCR_022688) Copy
https://www.umassmed.edu/scope/
Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.
Proper citation: University of Massachusetts Medical School Sanderson Center for Optical Experimentation Core Facility (RRID:SCR_022721) Copy
https://ag.purdue.edu/department/arge/facilities-and-research/microscopy/index.html
Provides Purdue researchers access to electron microscopy instrumentation including scanning electron microscopes, small dual beams and transmission electron microscopes. Expert staff scientists help with training and project support.
Proper citation: Purdue Electron Microscopy Center (RRID:SCR_022687) Copy
https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php
Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.
Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy
https://irp.drugabuse.gov/organization/core-facilities/genetic-engineering/
Provides support to NIDA-IRP researchers by facilitating studies of brain function under physiological and pathological conditions through developing and producing genetic tools capable of modulating and monitoring molecules, cells and circuits in nervous system.Provided services include custom design and/or production of viral vectors/nanoparticles;in vitro molecular and cell biology services; consultation and training.
Proper citation: National Institute on Drug Abuse Genetic Engineering and Viral Vector Core Facility (RRID:SCR_022969) Copy
https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/
Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.
Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy
https://www.nebraskamed.com/neurological-care/meg-center
Equipped with magnetoencephalography (MEG) scanner to detect immediate changes in electrical brain activity. Provides 306 channel whole head MEG system (TRIUX, Neo, MEGin) and 128 channels EEG amplifier.MEG helmet does coverage for whole cortex, 1220 cm2. MEG system has three measurement positions:supine, lower and upper seated. MEG system is housed within magnetic shielded room equipped with active shielding and automated helium recycler.
Proper citation: University of Nebraska Medical Center UNMC MEG Core Facility (RRID:SCR_023033) Copy
https://www.med.unc.edu/humancellcore/
Provides services to conduct basic as well as translational research using human induced pluripotent cells. Offers Reprogramming, Genome editing and directed cell differentiation.
Proper citation: University of North Carolina at Chapel Hill Human Pluripotent Cell Core Facility (RRID:SCR_023246) Copy
Provides germ free and gnotobiotic mice, space in which investigators can complete their own studies or hire core to complete experimental manipulations.Facility includes 12 large soft sided vinyl isolators for breeding and 8 small soft sided vinyl isolators for experiments. There is option between using Allentown positive pressure racks and static cage for experimental use.
Proper citation: University of Colorado Anschutz Medical Campus Gnotobiotic Core Facility (RRID:SCR_023245) Copy
https://research.med.psu.edu/core-facilities/biomolecular-nmr/
Provides services for multiple modern NMR applications, including structure elucidation of small molecules, triple resonance experiments of biomolecules, fragment-based drug discovery, metabolomic and tissue analyses.
Proper citation: Penn State College of Medicine Biomolecular NMR Core Facility (RRID:SCR_023244) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/biomolecular-interactions-properties
Provides investigators with access to advanced tools for measuring biomolecular interactions and properties through variety of techniques from high throughput screening via automation to single reaction cuvette based methods.Facility complements technologies and techniques available through our Imaging facility and Proteomics and Metabolomics facility.
Proper citation: Cornell University Biotechnology Resource Center Biomolecular Interactions and Properties Core Facility (RRID:SCR_023117) Copy
https://chemh.stanford.edu/research/knowledge-centers
Shared resource to provide instrumentation and scientific expertise to Stanford researchers.Each Knowledge Center is organized around specific scientific area and offers services to the research community. Services, advice, training and instrument access, include area in High-Throughput Screening, Medicinal Chemistry, Crystallography, Cryo-EM, Metabolomics, Protein engineering, Protein expression.
Proper citation: Stanford Sarafan Chemistry, Engineering and Medicine for Human Health Knowledge Centers Core Facility (RRID:SCR_023238) Copy
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