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Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.
Proper citation: University of Notre Dame ND Biophysics Instrumentation Core Facility (RRID:SCR_023867) Copy
https://www.uniklinik-freiburg.de/medizin1/forschung/lighthouse-core-facility.html
Core specializes in areas of flow cytometry and cell sorting; light microscopy including confocal, widefield fluorescence, high content screening, lightsheet, slide scanning, highly multiplexed microscopy; and digital PCR / QPCR. It is located at University of Freiburg Medical Center and hosts institutions including Dept. of Medicine I, Center for Chronic Immunodeficiency (CCI), CCCF / DKTK, and Medical Faculty of University of Freiburg.
Proper citation: University of Freiburg Medical Center Lighthouse Core Facility (RRID:SCR_023785) Copy
Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.
Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy
https://sciex.com/products/mass-spectrometers/qtof-systems/tripletof-systems/tripletof-5600-system
Mass spectrometry system that combines SCIEX Triple Quad technology with Accelerator TOF Analyzer, to deliver nominal mass and accurate mass benefits in single platform. Integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows.
Proper citation: SCIEX TripleTOF 5600+ Mass Spectrometer System (RRID:SCR_018053) Copy
Real-time PCR system that performs high performance, multicolor real-time PCR. Has five color platform that is calibrated for broadest range of dyes available: FAM, SYBR Green I, VIC, JOE, NED, TAMRA, Cy3, ROX, Texas Red, and Cy5 dyes. Thermal cycling block is built to reduce environmental exposure and contamination risk.
Proper citation: Applied Biosystems 7500 Real-Time PCR System (RRID:SCR_018051) Copy
Benchtop flow cytometer features reliable performance and accurate results for experiments requiring up to 10 parameters. Fixed alignment flow cell minimizes startup time and improves reproducibility. Patented optical design maximizes signal detection and increases sensitivity and resolution for each color in multicolor assay.
Proper citation: BD Scientific Canto II Flow Cytometer (RRID:SCR_018056) Copy
Multimode microplate reader that provides speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Provides higher sensitivity for time-resolved fluorescence TRF applications, and Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments GxP.
Proper citation: EnVision 2105 Multimode Plate Reader (RRID:SCR_018038) Copy
http://www.syntechinnovation.com/images/catalog/advance-analytical/8chromatography/HPLC_Brochure.pdf
Liquid chromatography analyzer that achieves high levels of sample throughput by use of either binary or quaternary pumps and interchangeable autosamplers. High pressure operation and use of short columns with small diameter media result in fast, high resolution separations. Features includedu al-lamp design and temperature control of diode array detectors.
Proper citation: Agilent 1200 High Performance Liquid Chromatography System (RRID:SCR_018037) Copy
https://www.tekyard.com/Item/inventoryId/209687
Molecular imager system for performing gel and blot analysis. This system provides both PhosphorImager capabilities along with non-radioactive fluorescent labeling techniques-direct fluorescence and chemifluorescence. It can be used for non-radioactive gel and blot analysis methods or radioisotope techniques. Storm 840 scans storage phosphor screens plus fluorescent gels and chemifluorescent blots in the 35 x 43 cm scanning area.
Proper citation: Molecular Dynamics Storm 840 Molecular Imager (RRID:SCR_018031) Copy
http://apexx-equipment.com/veterinary-mfg/agfa/agfa-cp1000-automatic-film-processor-1
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10,2024. Automatic film processor for low-volume processing or back-up purposes. Its features include fast start up (7 minutes from cold start) and 125-second cycle time. Uses simple, accessible film transport system with fewer rollers than conventional heavy roller racks, infrared dryer instead of hot-air dryer, 400 watts of power when in operation and 100 watts in standby mode, and automatic temperature control and drying.
Proper citation: AGFA CP1000 Automatic Film Processor (RRID:SCR_018030) Copy
https://www.thermofisher.com/order/catalog/product/00-0079#/00-0079
Microarray processor that washes and stains GeneChip arrays.110V and 220V compatible.
Proper citation: Affymetrix GeneChip 450 Fluidics Station Microarray Processer (RRID:SCR_018034) Copy
Microarray scanner that performs genetic and compound analysis. Coupled with GenePix ProMicroarray Image Analysis Software and Acuity Microarray Informatics Software for acquisition and analysis of data from all types of arrays, including nucleic acids, proteins, tissues, and cells. Scanner flexibility allows to configure scanning and analysis of one slide or many, whether they are all alike or each is different. Slide loader accommodates low- and high-density, opaque, mirrored, or translucent, plastic or glass, commercial or homebrew slides.
Proper citation: Molecular Devices GenePix 4000B Microarray Scanner (RRID:SCR_018049) Copy
https://www.thermofisher.com/order/catalog/product/ND-2000
Full-spectrum, UV-Vis spectrophotometer used to quantify and assess purity of DNA, RNA, Protein and more. The NanoDrop 2000 is microvolume spectrophotometer with patented sample retention technology that measure sample volumes as small as 0.5L.
Proper citation: Thermo Scientific NanoDrop 2000 Spectrophotometer (RRID:SCR_018042) Copy
Personal sized 96-well thermal cycler that performs both basic PCR and cycle-sequencing applications using 0.2 mL reaction tubes or 96-well reaction plates. Its dimensions are 21 cm (8.3 in.) wide and 36 cm (14.2 in.) deep with cooling vents.
Proper citation: Applied Biosystems 2720 Thermal Cycler (RRID:SCR_018045) Copy
https://www.labx.com/product/roche-454-gs-flx
Genetic sequencer that sequences clinically relevant exons and identifies genomic variations in solid tumors treated with antibody-based medicine. Scaled version of Genome Sequencer FLX System for use by individual labs. Features include simple sample preparation workflow, overnight sequencing and data processing, and suite of data analysis software.
Proper citation: Roche 454 GS FLX Genome Sequencer (RRID:SCR_018028) Copy
https://www.bio-rad.com/en-us/product/bio-plex-200-systems?ID=715b85f1-6a4e-41b3-b5d9-80202d779e13
Suspension array system which offers protein and nucleic acid researchers multiplex assay solution permiting analysis of up to 100 biomolecules in single sample.
Proper citation: BioRad Bio-Plex 200 System (RRID:SCR_018026) Copy
https://www.luminexcorp.com/research-luminex-100200/
Flow cytometry analyzer system for individual labs that performs up to 100 different tests in single reaction volume and can use either magnetic beads or plain polystyrene beads. Luminex 200 offers higher sample throughput with 96-well plate read time of only 45 minutes.
Proper citation: Luminex 100 or 200 Flow Cytometry Analyzer System (RRID:SCR_018025) Copy
https://www.warneronline.com/dual-channel-temperature-controller-tc-344c
Temperature controller. Each channel supplies up to 22 watts into load of 10 ohms. Heat set point is controlled automatically in Auto mode via thermistor feedback. Loop speed selector provides three feedback response times to optimize tp thermal stability of device being heated. Heat set-point may also be manually controlled in Manual mode.
Proper citation: Warner Instruments Dual Channel Temperature Controller Model TC-344C (RRID:SCR_023068) Copy
https://www.microscopyu.com/museum/eclipse-te2000-inverted-microscope
TE2000 was developed as full system with 3 models, the S, the U and the E. TE2000E is high precision Z-focus automated model that features 5 output ports and 5-way motorized light path changer. Used for advanced research that requires image capture in 3D, including confocal microscopy and deconvolution processing.TE2000U is universal model that comes with 4 output ports as standard, plus optional fifth user defined position, thereby providing unprecedented 5-way light path.The U model also features integrated magnification changer module providing 1x or 1.5x magnification to all ports.
Proper citation: Nikon Eclipse TE2000 inverted microscope system (RRID:SCR_023161) Copy
150 mm focal length monochromator/spectrograph. It features astigmatism corrected optical system, dual indexable gratings and interchangeable grating turrets.
Proper citation: Teledyne Princeton Instruments SpectraPro 2150 imaging spectrograph (RRID:SCR_023163) Copy
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