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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb data repository, storage service resource, data analysis service, portal, analysis service resource, data or information resource, production service resource, service resource, topical portal, database PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb
https://doi.org/10.17616/R39D13
SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-02-14 02:04:53 21
PASA
 
Resource Report
Resource Website
500+ mentions
PASA (RRID:SCR_014656) sequence analysis software, data processing software, data analysis software, software application, software resource Gene structure annotation and analysis tool that uses spliced alignments of expressed transcript sequences to automatically model gene structures. It also incorporates gene structures based on transcript alignments into existing gene structure annotations. It is one component of a larger eukayotic annotation pipeline implemented at the Broad Institute. gene structure, annotation, gene structure analysis tool, spliced alignment, transcript sequence, bio.tools is used by: BRO_annotation
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/nar/gkg770 Available for download biotools:PASA https://bio.tools/PASA SCR_014656 Program to Assemble Spliced Alignments (PASA), Program to Assemble Spliced Alignments 2026-02-14 02:04:50 999
Molecular Dynamics Workflow (BioKepler)
 
Resource Report
Resource Website
1+ mentions
Molecular Dynamics Workflow (BioKepler) (RRID:SCR_014389) software resource, workflow software, data processing software, software application A workflow for running molecular dynamics simulations. It can be used for all-atom molecular dynamic simulations, which involve five steps of minimization, one step of heating, three steps of equilibration, and one or more instances of production. The input is a set of directories that include the MD simulation input scripts, system topology and coordinate files. Output files are list of plots, simulation trajectories, intermediate files, restart files, and the like. workflow, MD, molecular dynamics, simulation, software, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: bioKepler
has parent organization: University of California at San Diego; California; USA
NIGMS P41GM103426 Requires Linux biotools:ambergpumdsimulation http://nbcr.ucsd.edu/data/downloads/workflows/
https://bio.tools/ambergpumdsimulation
SCR_014389 Molecular Dynamics Workflow, AmberGPUMDSimulation, Molecular Dynamics Workflow Software, Amber GPUMD Simulation 2026-02-14 02:04:50 1
PLINK/SEQ
 
Resource Report
Resource Website
50+ mentions
PLINK/SEQ (RRID:SCR_013193) software resource, software library, software toolkit, software application An open-source C/C++ library for working with human genetic variation data. The specific focus is to provide a platform for analytic tool development for variation data from large-scale resequencing projects, particularly whole-exome and whole-genome studies. However, the library could in principle be applied to other types of genetic studies, including whole-genome association studies of common SNPs. (entry from Genetic Analysis Software) gene, genetic, genomic, c/c++, r, macos, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: PLINK
has parent organization: Harvard University; Cambridge; United States
Open unspecified license nlx_154213, biotools:plink-seq https://bio.tools/plink-seq SCR_013193 2026-02-14 02:04:35 77
fineSTRUCTURE
 
Resource Report
Resource Website
10+ mentions
fineSTRUCTURE (RRID:SCR_018170) data analysis software, software resource, data processing software, software application Software tool as algorithm for identifying population structure using dense sequencing data. Can perform model based Bayesian clustering on large datasets, including full resequencing data. Identifying population structure, dense sequencing data, Bayesian clustering, large dataset, data, analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:finestructure https://bio.tools/finestructure SCR_018170 FineSTRUCTURE version 2 2026-02-14 02:03:28 23
ChiCMaxima
 
Resource Report
Resource Website
1+ mentions
ChiCMaxima (RRID:SCR_018178) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling. Chromatin loop, CHi-C promoter, data, Hi-C visualization, interaction calling, data, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31118054 Free, Freely available biotools:ChiCMaxima https://bio.tools/ChiCMaxima SCR_018178 2026-02-14 02:03:17 2
SnpHub
 
Resource Report
Resource Website
1+ mentions
SnpHub (RRID:SCR_018177) software resource, web application Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data. Genomic, data, data visualization, data analysis, data retrieving, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31701415;
National Key Research and Development Program of China 2018YFD0100803;
National Key Research and Development Program of China 2016YFD0100801
Free, Available for download, Freely available biotools:SnpHub http://guoweilong.github.io/SnpHub/
https://bio.tools/SnpHub
SCR_018177 2026-02-14 02:03:34 1
SpydrPick
 
Resource Report
Resource Website
1+ mentions
SpydrPick (RRID:SCR_018176) data analysis software, software resource, data processing software, software application Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree. Direct coupling analysis, aligned categorical datasets, analysis, genome, bacteria, phylogenetic signal, correction, phylogenetic tree, data, bio.tools is listed by: Debian
is listed by: bio.tools
COIN Center of Excellence ;
Academy of Finland ;
Wellcome Trust ;
European Research Council
PMID:31361894 Free, Available for download, Freely available biotools:SpydrPick https://anaconda.org/bioconda/spydrpick
https://bio.tools/SpydrPick
SCR_018176 2026-02-14 02:03:28 2
CRISPRdirect
 
Resource Report
Resource Website
100+ mentions
CRISPRdirect (RRID:SCR_018186) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Software for designing CRISPR/Cas guide RNA with reduced off target sites. Used for rational design of CRISPR/Cas target. Web server for selecting rational CRISPR/Cas targets from input sequence. Server currently incorporates genomic sequences of human, mouse, rat, marmoset, pig, chicken, frog, zebrafish, Ciona, fruit fly, silkworm, Caenorhabditis elegans, Arabidopsis, rice, Sorghum and budding yeast. CRISP/Cas guide RNA, reduced off target site, design of CRISP/Cas target, selecting rational target, sequence, genomic sequence, RNA, bio.tools is listed by: Debian
is listed by: bio.tools
Japan Science and Technology Agency ;
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan
PMID:25414360 Free, Freely available biotools:CRISPRdirect https://bio.tools/CRISPRdirect SCR_018186 2026-02-14 02:03:28 452
Fcirc
 
Resource Report
Resource Website
1+ mentions
Fcirc (RRID:SCR_018090) Fcirc software resource, workflow software, data processing software, software application Software Python pipeline for linear and circular RNAs of known fusions exploration. Pipeline for exploring linear transcripts and circRNAs of known fusions based on RNA-Seq data. Known fusion genes are from multiple databases like COSMIC, ChimerDB, TicDB, FARE-CAFE and FusionCancer or user-added gene-pairs. Fusion gene, linear and circular RNA, fusion exploration, RNAseq data, linear transcript, circRNA, gene, data, pipeline, bio.tools uses: HISAT2
uses: SAMTOOLS
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31771469 ;
National Natural Science Foundation of China 31571363 ;
National Natural Science Foundation of China 81573023 ;
National Key Research and Development Program 2017YFC0908500
Free, Available for download, Freely available biotools:Fcirc https://bio.tools/Fcirc SCR_018090 Comprehensive Pipeline for Exploration of Fusion Linear and Circular RNAs 2026-02-14 02:03:30 2
HingeProt
 
Resource Report
Resource Website
1+ mentions
HingeProt (RRID:SCR_018136) data access protocol, software resource, web service, service resource Web server for predicting rigid protein parts and flexible hinge regions connecting them in native topology of protein chains by employing elastic network (EN) models. Automated prediction of hinges in protein structures. Predicting protein hinges, flexible hinge region, native topology, rigid protein part, elastic network model, protein structure, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:17847101 Free, Available for download, Freely available biotools:hingeprot https://bio.tools/hingeprot SCR_018136 2026-02-14 02:03:17 4
Warp
 
Resource Report
Resource Website
1+ mentions
Warp (RRID:SCR_018071) data processing software, data acquisition software, data analysis software, software application, software resource Software tool that automates all preprocessing steps of cryo-EM data acquisition and enables real-time evaluation. Corrects micrographs for global and local motion, estimates local defocus and monitors key parameters for each recorded micrograph or tomographic tilt series in real time. Software includes deep-learning-based models for accurate particle picking and image denoising. Automating preprocessing step, cryo EM data acquisition, micrograph correction, particle picking, image denoising, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/s41592-019-0580-y Free, Available for download, Freely available BioTools:Warp, biotools:Warp https://bio.tools/Warp
https://bio.tools/Warp
https://bio.tools/Warp
SCR_018071 2026-02-14 02:03:16 7
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) web service, software application, data access protocol, software resource, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-14 02:03:27 149
CLIP-Explorer
 
Resource Report
Resource Website
1+ mentions
CLIP-Explorer (RRID:SCR_018128) data visualization software, data processing software, data analysis software, service resource, software application, software resource Webserver to process, analyse and visualise CLIP-Seq data. Software tools to process and visualise RNA protein interactions. CLIP-Seq data analysis in Galaxy. Galaxy CLIP-Explorer can process large CLIP-Seq data of eCLIP, iCLIP, and with simple changes to iCLIP workflows also FLASH, and uvCLAP. CLIP-seq data, RNA protein interaction, Galaxy, data analysis, eCLIP, iCLIP, FLASH, uvCLAP, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
is related to: FLASH
Restricted SCR_018130, biotools:CLIP-Explorer https://bio.tools/CLIP-Explorer SCR_018128 2026-02-14 02:03:31 2
PlotTwist
 
Resource Report
Resource Website
10+ mentions
PlotTwist (RRID:SCR_018331) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Web application for plotting and annotating continuous data. Open source web app for plotting and annotating time series data. Used to inspect data and generate publication quality visualizations. Available options for plotting include lineplot, small multiples and heatmap, summary statistics and inferential statistics. Plotting continuous data, annotating continuous data, data visualization, time series data, line plot, small multiples, heatmap, statistic, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31929523 Free, Freely available biotools:Plottwist, BioTools:PlotTwist https://github.com/JoachimGoedhart/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
SCR_018331 PlotTwist Shiny 2026-02-14 02:03:19 10
CRISPRcasIdentifier
 
Resource Report
Resource Website
1+ mentions
CRISPRcasIdentifier (RRID:SCR_018296) data analysis software, software resource, data processing software, software application Software tool providing machine learning approach for identification and classification of CRISPR-Cas systems. Combines regression and classification approaches for improving quality of input protein cassettes and predicting their subtypes. CRISPR-Cas, Machine Learning, Cas genes, Cas proteins, input protein cassette, predicting subtype, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/817619 Free, Available for download, Freely available biotools:crisprcasidentifier https://bio.tools/crisprcasidentifier SCR_018296 2026-02-14 02:03:19 4
SymPy
 
Resource Report
Resource Website
1+ mentions
SymPy (RRID:SCR_018417) software resource, software library, software toolkit Software Python library for symbolic mathematics. It aims to become full featured computer algebra system (CAS) while keeping code as simple as possible in order to be comprehensible and easily extensible. Python, Python library, symbolic mathematics, computer algebra system, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:SymPy https://bio.tools/SymPy SCR_018417 2026-02-14 02:03:20 9
smashpp
 
Resource Report
Resource Website
1+ mentions
smashpp (RRID:SCR_018307) data visualization software, data processing software, data analysis software, software application, software resource Software tool to find and visualize rearrangements in DNA sequences. Find sequence rearrangement, visualize sequence rearrangement, DNA, DNA sequence, DNA sequence rearrangement, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:smashpp, BioTools:smashpp https://bio.tools/smashpp
https://bio.tools/smashpp
https://bio.tools/smashpp
SCR_018307 Smash++ 2026-02-14 02:03:33 2
GPS-SUMO
 
Resource Report
Resource Website
1+ mentions
GPS-SUMO (RRID:SCR_018261) web service, portal, data or information resource, service resource, data access protocol, software resource Web service for prediction of SUMOylation sites and SUMO-interaction motifs in proteins by CUCKOO Workgroup. Small ubiquitin like modifier, SUMOs, sumoylation, covalently modified protein, group prediction system, site prediction, interaction motif in protein, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
National Basic Research Program ;
Guangdong Natural Science Funds for Distinguished Young Scholar ;
Zhujiang Nova Program of Guangzhou ;
International Science and Technology Cooperation Program of China
PMID:24880689 Restricted biotools:gps-sumo http://sumosp.biocuckoo.org/online.php
https://bio.tools/gps-sumo
SCR_018261 Group-based Prediction System -Small Ubiquitin-like MOdifiers, Small Ubiquitin-like MOdifiers sp, GPS-SUMO 2.0, SUMOsp, GPS Small Ubiquitin-like MOdifiers, Group-based Prediction System-SUMO 2026-02-14 02:03:33 2
NanoSim
 
Resource Report
Resource Website
10+ mentions
NanoSim (RRID:SCR_018243) software resource, simulation software, software application Software tool as Nanopore sequence read simulator based on statistical characterization. Oxford Nanopore Technology sequence simulator written in Python and R. Benefits development of scalable next generation sequencing technologies for long nanopore reads, including genome assembly, mutation detection, and metagenomic analysis software. Nanopore sequence read, sequence simulator, Oxford Nanopore Technology, next generation sequencing, long nanopore read, genome assembly, mutation detection, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
NHGRI R01 HG007182;
Genome Canada ;
Genome British Columbia ;
British Columbia Cancer Foundation ;
University of British Columbia
DOI:10.1093/gigascience/gix010 Free, Available for download, Freely available biotools:trans-nanosim, biotools:nanosim https://www.bcgsc.ca/resources/software/nanosim
https://bio.tools/nanosim
https://bio.tools/Trans-NanoSim
SCR_018243 2026-02-14 02:03:32 18

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