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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://bmslab.sitehost.iu.edu/index.html
Core uses mass spectrometry to characterize proteins as well as other biologically-derived molecules. Specializes in characterization of protein post-translational modifications, including glycosylation, phosphorylation, acetylation and persulfidation.Provides identification of protein-interactions including determination of protein-protein crosslinks and quantitative comparisons of complex samples.
Proper citation: Indiana University Bloomington Laboratory for Biological Mass Spectrometry Core Facility (RRID:SCR_025591) Copy
https://medicine.iu.edu/service-cores/facilities/imaging-flow-cytometry
Provides standard confocal or multiphoton resources for imaging live or fixed samples and a 5 color flow cytometric analyzer are available. Data analysis software for each resource is also available on site.
Proper citation: Indiana University School of Medicine South Bend Imaging and Flow Cytometry Core Facility (RRID:SCR_025560) Copy
https://medicine.iu.edu/radiology/research/imaging-core
Core provides imaging services for clinical trials, observational, and preclinical studies. Provides radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities.
Proper citation: Indiana University School of Medicine In-Vivo Imaging Core Facility (RRID:SCR_025567) Copy
https://www.purdue.edu/discoverypark/bioscience/facilities/core/genomics/index.php
Core provides both next generation Illumina NovaSeq and MiSeq and Sanger sequencing with additional method to provide entire plasmid sequences via service called WideSeq.
Proper citation: Purdue University Bindley Genomics Core Facility (RRID:SCR_025557) Copy
https://cncm.som.uci.edu/viral-core/
Viral production facility aims at development and production of viral vectors for in-vivo and in-vitro experimentation purposes. Equipment coupled with our expertise allows use to ensure high quality products. Provides all related sequence data, vector maps, plasmids and ready-to-use viruses once your orders are completed.
Proper citation: University of California Irvine Center for Neural Circuit Mapping Viral Core Facility (RRID:SCR_025573) Copy
https://www.pedsresearch.org/research/cores/biomarkers-core
Biomarkers Core offers high quality analysis of biological samples to support pediatric research. Provides equipment and technical expertise to assay samples using methods that combine the features of gas-liquid chromatography and mass spectrometry.
Proper citation: Emory University Pediatric Biomarkers Core Facility (RRID:SCR_025574) Copy
https://cancer.iu.edu/research/shared-facilities/pmtc/ivt.html
Core supports research and development of safe and more efficacious drug treatment. Provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as in vivo pharmacology models to facilitate development and testing of novel pharmacological and cellular therapies.
Proper citation: Indiana University School of Medicine In Vivo Therapeutics Core Facility (RRID:SCR_025569) Copy
http://www.uab.edu/shp/drc/animal-physiology-core-links
Core that provides diabetes researches with diabetes related phenotyping in small animal models. Their services offered include the assessment of body composition, energy balance, glucose homeostasis, cardiovascular assessment, imaging, and transgenic animals models.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015110) Copy
https://tools.neurophotonics.ca/
Core facility responsible for custom adeno-associated virus (AAV) and lentivirus production available through Canadian Neurophotonics Platform. Services include design, cloning and production of molecular constructions in order to produce plasmid expression vectors or to generate transgenic animals and design, including advice and assistance for choice of suitable vectors required by investigators.
Proper citation: CERVO Canadian Optogenetics and Vectorology Foundry Core Facility (RRID:SCR_016477) Copy
https://core.bioinformatics.udel.edu
CBCB Bioinformatics Data Science Core builds upon infrastructure of the Center for Bioinformatics and Computational Biology. Delaware Biotechnology Institute , Delaware Data Science Institute, and Protein Information Resource. Core helps with planning your research or analyzing your current data. Services:Consultation and Collaboration, Proposal Assistance,Training, Bioinformatics Software, Computational Hardware, Database and Web Services, Next Gen Analysis, Custom Analysis.
Proper citation: University of Delaware CBCB Bioinformatics Data Science Core Facility (RRID:SCR_017696) Copy
https://molbio.princeton.edu/core-facilities/confocal-microscopy
Core provides researchers with ability to visualize samples, from monolayers and small organisms, such as developing fly and fish embryos, to very thick sections from brain and other organ tissues by using instruments including laser point (LSCM) and field scanning confocal (CSU), Total Internal Reflectance Fluorescence (TIRF), Multi Photon (MP), and Widefield (WF). Services in imaging in mammalian cells, yeast cells, Drosophila and Zebrafish embryos and ovaries, bacteria, sections of brain and other tissues, in both fixed and live specimens, Quantitative imaging methods such as FRAP, FLIP, and FRET, software packages for image processing, analysis, and 3D image reconstruction.
Proper citation: Princeton University Confocal Microscopy Core Facility (RRID:SCR_017812) Copy
Genomics and transcriptomics core at the UCD Genome Center provides high throughput sequencing, genotyping, single-cell multi-omics and spatial transcriptomics services, training and consultation. Initial consultations are free. The lab uses liquid handling robots to minimize sample handling variation and to provide fast turnaround times.
Proper citation: University of California Davis DNA Technologies and Expression Analysis Core Facility (RRID:SCR_017740) Copy
Core provides services and houses samples collected over the last 30 years. Biorepository processes, archives, and retrieves biological samples for genomic research. Offers variety of sample processing options including but not limited to automated DNA extraction using Autogen FLEXSTAR+ instrument, automated DNA/RNA extraction using Qiagen QIASymphony, peripheral blood mononuclear cell (PBMC) isolation, serum, plasma and buffy coat isolation, creation of blood cards, DNA/RNA quantitation and qualitation, whole genome amplification, cell-line lymphoblast immortalization and primary fibroblast tissue culture. Offers sample solutions tos uit customized needs.Services also include DNA/RNA Extraction,Sample archiving, retrieval and allocation,Unique and custom labels printing,DNA/RNA quantitation and qualitation,Tissue culture,Whole genome amplification.
Proper citation: University of Miami Hussman Institute for Human Genomics Biorepository Core Facility (RRID:SCR_017816) Copy
https://chemistry.as.miami.edu/research-facilities/mass-spectrometry-laboratory/index.html
Core provides two mass spectrometers at UM Department of Chemistry, Bruker MicroQ-TOF ESI, and Agilent Technologies 5975C GC/MS with autosampler.
Proper citation: Miami University Mass Spectroscopy Laboratory Core Facility (RRID:SCR_017819) Copy
http://www.kumc.edu/mspc.html/
Core provides access to mass spectrometry based proteomics applications, customizes mass spectrometry designs that fit individual needs. Used for general proteomics evaluations and protein identification designs, quantitation techniques, hydrogen/deuterium exchange, and oxidative footprinting. Equipment includes Orbitrap Fusion Lumos.
Proper citation: Kansas University Medical Center Mass Spectrometry/Proteomics Core Facility (RRID:SCR_017818) Copy
https://www.aicjanelia.org/about
Facility provides imaging methods and instruments, microscopes that reveal biological processes in three-dimensional detail and behavior of single molecules in high resolution. Welcomes proposals with high-risk/high-gain projects. AIC will cover lodging and basic experimental cost for scientists whose proposals have been accepted to come to Janelia to perform their experiments.
Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Advanced Imaging Center Core Facility (RRID:SCR_017823) Copy
http://cpl.med.miami.edu/services/
Full service veterinary reference laboratory directed by members of faculty of University of Miami Miller School of Medicine. Offers clinical pathology and histopathology services to meet needs of avian, exotic, lab animal, and wildlife veterinarians. Services include Acute Phase Protein Laboratory. Provides recent diagnostic testing developments which may not yet be available in other veterinary diagnostic testing environments.
Proper citation: Miami University Veterinary Clinical Pathology Laboratory Core Facility (RRID:SCR_017822) Copy
http://hihg.med.miami.edu/cgt/genotyping
Core provides services in analyzing genetic variation, performing genome-wide association studies, conducting non-human genotyping. Offers flexible platforms from low to high throughput, tailored to research needs. Specializes in Illumina Genotyping Arrays and TaqMan Allelic Discrimination Assays, with fully automated processing using Tecan EVOs and BioMek liquid handlers and Genologics LIMS for reliable data tracking.Applications include: GWAS – Identify genetic variants linked to traits and diseases; PRS Analysis – Assess genetic risk for complex diseases; Pharmacogenomics – Study genetic factors in drug response; Population Genetics – Explore ancestry and genetic diversity; CNV Analysis – Detect large-scale genomic variations; Methylation Analysis.
Proper citation: University of Miami Hussman Institute for Human Genomics Genotyping Core Facility (RRID:SCR_017820) Copy
https://wertheim.scripps.ufl.edu/cores-and-technologies/genomics-core/
Core provides services in Next Generation Sequencing (NGS), library preparation, consultation on sample preparation and procedures.
Proper citation: Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology Genomics Core Facility (RRID:SCR_017827) Copy
Core Facility offers services utilizing Illumina Novaseq X Plus, Pacific Biosciences Revio, ONT Promethion, and 10x Genomics platforms. The core has extensive knowledge of DNA/RNA library preparation for short-read, long-read and single cell sequencing. Sample preparation is fully automated on Perkin Elmer robotic workstations and tracked via the Clarity LIMS. Services include, but are not limited to, whole genome, exome and custom capture protocols, as well as, bulk RNAseq, small RNAseq, and single cell RNA sequencing.
Proper citation: University of Miami Hussman Institute for Human Genomics Sequencing Core Facility (RRID:SCR_017828) Copy
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