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https://drexel.edu/core-facilities/facilities/cell-imaging/

Facility housed in purpose built imaging suites in Papadakis Integrated Sciences Building and in Bossone Research Center. Serves light microscopy needs of Drexel researchers and supports teaching missions of Biology and Biomedical Engineering curricula and provides service to users from local biotech companies.Provides facility, expertise, and education in advanced quantitative light microscopy.

Proper citation: Drexel University Cell Imaging Center Core Facility (RRID:SCR_022689) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/cbb/

Provides support for students, postdoctoral fellows, and faculty interested in the use of computational approaches to solving biological problems. Our goal is to lower as much as possible the threshold to enter the -omics area of the life sciences.

Proper citation: University of Texas at Austin Computational Biology and Bioinformatics Core Facility (RRID:SCR_022688) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/scope/

Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.

Proper citation: University of Massachusetts Medical School Sanderson Center for Optical Experimentation Core Facility (RRID:SCR_022721) Copy   

•   Source: SciCrunch Registry

https://ag.purdue.edu/department/arge/facilities-and-research/microscopy/index.html

Provides Purdue researchers access to electron microscopy instrumentation including scanning electron microscopes, small dual beams and transmission electron microscopes. Expert staff scientists help with training and project support.

Proper citation: Purdue Electron Microscopy Center (RRID:SCR_022687) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php

Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.

Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy   

•   Source: SciCrunch Registry

https://irp.drugabuse.gov/organization/core-facilities/genetic-engineering/

Provides support to NIDA-IRP researchers by facilitating studies of brain function under physiological and pathological conditions through developing and producing genetic tools capable of modulating and monitoring molecules, cells and circuits in nervous system.Provided services include custom design and/or production of viral vectors/nanoparticles;in vitro molecular and cell biology services; consultation and training.

Proper citation: National Institute on Drug Abuse Genetic Engineering and Viral Vector Core Facility (RRID:SCR_022969) Copy   

•   Source: SciCrunch Registry

https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/

Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.

Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy   

•   Source: SciCrunch Registry

https://www.nebraskamed.com/neurological-care/meg-center

Equipped with magnetoencephalography (MEG) scanner to detect immediate changes in electrical brain activity. Provides 306 channel whole head MEG system (TRIUX, Neo, MEGin) and 128 channels EEG amplifier.MEG helmet does coverage for whole cortex, 1220 cm2. MEG system has three measurement positions:supine, lower and upper seated. MEG system is housed within magnetic shielded room equipped with active shielding and automated helium recycler.

Proper citation: University of Nebraska Medical Center UNMC MEG Core Facility (RRID:SCR_023033) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/humancellcore/

Provides services to conduct basic as well as translational research using human induced pluripotent cells. Offers Reprogramming, Genome editing and directed cell differentiation.

Proper citation: University of North Carolina at Chapel Hill Human Pluripotent Cell Core Facility (RRID:SCR_023246) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/rheumatology/research/research-services/gnotobiotic-core-service-center

Provides germ free and gnotobiotic mice, space in which investigators can complete their own studies or hire core to complete experimental manipulations.Facility includes 12 large soft sided vinyl isolators for breeding and 8 small soft sided vinyl isolators for experiments. There is option between using Allentown positive pressure racks and static cage for experimental use.

Proper citation: University of Colorado Anschutz Medical Campus Gnotobiotic Core Facility (RRID:SCR_023245) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/biomolecular-nmr/

Provides services for multiple modern NMR applications, including structure elucidation of small molecules, triple resonance experiments of biomolecules, fragment-based drug discovery, metabolomic and tissue analyses.

Proper citation: Penn State College of Medicine Biomolecular NMR Core Facility (RRID:SCR_023244) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/biomolecular-interactions-properties

Provides investigators with access to advanced tools for measuring biomolecular interactions and properties through variety of techniques from high throughput screening via automation to single reaction cuvette based methods.Facility complements technologies and techniques available through our Imaging facility and Proteomics and Metabolomics facility.

Proper citation: Cornell University Biotechnology Resource Center Biomolecular Interactions and Properties Core Facility (RRID:SCR_023117) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers

Shared resource to provide instrumentation and scientific expertise to Stanford researchers.Each Knowledge Center is organized around specific scientific area and offers services to the research community. Services, advice, training and instrument access, include area in High-Throughput Screening, Medicinal Chemistry, Crystallography, Cryo-EM, Metabolomics, Protein engineering, Protein expression.

Proper citation: Stanford Sarafan Chemistry, Engineering and Medicine for Human Health Knowledge Centers Core Facility (RRID:SCR_023238) Copy   

•   Source: SciCrunch Registry

http://www.nextgen.pitt.edu

Sequencing Core offers Illumina next generation sequencing services to University of Pittsburgh research community. Offers expertise in next generation sequencing technologies. Encourages to contact Assistant Director to arrange for consultation.Staff is available to share their experience and expertise to assist with development of projects of all sizes, standard or custom assay design, and other specialized application needs.

Proper citation: University of Pittsburgh Medical Center Children Hospital of Pittsburgh Health Sciences Sequencing Core Facility (RRID:SCR_023116) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/protein-engineering

MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.

Proper citation: Stanford Sarafan Protein Engineering Knowledge Center Core Facility (RRID:SCR_023237) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/metabolomics

Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.

Proper citation: Stanford Sarafan Metabolomics Knowledge Center Core Facility (RRID:SCR_023236) Copy   

•   Source: SciCrunch Registry

https://ua.ilab.agilent.com/service_center/show_external/4535?name=analytical-and-biological-mass-spectrometry

Provides equipment and expertise for analysis of variety of biological and small molecules.Services include protein analysis encompassing protein identification, protein and peptide sequence confirmation, intact protein molecular weight determination, complex protein sample analysis, and protein/antibody drug interactions.Developed metabolomics library to support metabolomic and lipidomics analysis. Can identify range of post-translational modifications, determining their presence or absence, as well as quantitating PTMs.Proteomics and small molecule services include workflows for label free,chemical labeling (iTRAQ/TMT) and metabolic labeling (SILAC).Service for molecular synthesis, with monitoring reaction steps,calculating percentage of product, testing for purity, and molecule characterization with high resolution and high mass accuracy.Provides molecular weight and chemical composition determinations, structure elucidations and compound identification analysis or confirmation and accurate mass measurements of synthetic products, measurement of polymers, nucleic acids (DNA/RNA), peptides, proteins, natural products, and assistance with determination of unknowns.

Proper citation: University of Arizona Analytical and Biological Mass Spectrometry Core Facility (RRID:SCR_023370) Copy   

•   Source: SciCrunch Registry

http://www.arpege.cnrs.frCore FacilityArpege

Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).

Proper citation: Arpege Core Facility (RRID:SCR_023092) Copy   

•   Source: SciCrunch Registry

http://www.mgx.cnrs.fr

Offers genomic technologies to academic laboratories and biotechnology companies.Application portfolio includes Whole genome (re)sequencing, including the identification of variants (SNVs, mutations, indels, CNVs);Targeted sequencing, for instance exomes; Transcriptome analyses (RNA-Seq, small RNA-Seq, microarrays), including in single cells (single-cell 3 RNA-seq); Determination of chromatin structure and dynamics (ChIP-Seq, FAIRE-Seq, Hi-C); Epigenetic analyses (ChIP-Seq, RRBS, Bisulphite-Seq);Genotyping (RAD-Seq, GBS, microarrays).

Proper citation: Montpellier GenomiX Core Facility (RRID:SCR_023091) Copy   

•   Source: SciCrunch Registry

https://neuroscience.stanford.edu/research/neuroscience-community-labs/neuroscience-microscopy-service

Provides microscopy expertise and access to high resolution, state-of-the-art imaging technologies to Stanford University and surrounding academic and biotech researchers. Core provides training, design, implementation, and analysis assistance.

Proper citation: Stanford Neuroscience Microscopy Service Core Facility (RRID:SCR_023257) Copy   

•   Source: SciCrunch Registry