Tools   Select Another Resource Report Type

https://www.wistar.org/resources/flow-cytometry-facility/

Core facility that provides the following services: Immunophenotyping, Fluorescent protein expression analysis, Cell-cycle analysis, Functional assay service, Non-infectious cell sorting, BSL2+ biohazardous cell sorting, Flow cytometry consultation service, Flow cytometry training and ongoing advice, Flow cytometry data management service, Flow cytometry collaboration facilitation, Flow cytometer access. The Wistar Institute Flow Cytometry Shared Resource provides flow cytometric services, training, advice, and support for the use of flow cytometric techniques by Wistar Cancer Center investigators, as well as the greater basic research community.

Proper citation: Wistar Flow Cytometry Core Facility (RRID:SCR_010195) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-1120-feb3-dacb-da6080000000

The Rat Neurobehavioral Core provides equipment, training and consulting for Vanderbilt personnel who are interested in studying rat models of both neurological and psychiatric disorders. Examples of assays available for research in rats include models of anxiety, depression, drug abuse, learning and memory, cognition, attention, social interaction, pain, motor activity and coordination. Investigators can employ the latest technology in video capture and software-based analysis of behavior. Additionally, the facility offers a 24 hr/day home cage monitoring system that includes measurement of sleep EEG and core body temperature. A surgical suite is available, outfitted with a wide variety of equipment such as standard rat stereotaxic frames and a stereo-microscope, as well as various perfusion tables. Housing takes place inside the facility?s vivarium, which is Virus-Antibody free.

Proper citation: Vanderbilt Rat Neurobehavioral Laboratory (RRID:SCR_010196) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a23d-093e-b4bd-8a1180000000

The Tissue Core laboratory provides direct proteome profiling and protein imaging of intact tissues by MALDI-MS. The Core also provides proteome profiling of biofluids by MALDI-MS as they pertain to a specific disease.

Proper citation: Vanderbilt Tissue Core Laboratory (RRID:SCR_010199) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-10e8-f177-dacb-da6080000000

Core facility that provides the following services: Simple Protein Identification, Multidimensional Protein Identification Technology, 2D Difference Gel Electrophoresis (2D-DIGE). The Proteomics Laboratory provides state-of the-art MS instrumentation and analytical methods to analyze proteins and proteomes.

Proper citation: Vanderbilt Mass Spectrometry Research Center Proteomics Laboratory (RRID:SCR_010190) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/community/profile/id/1133

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.

Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-2ffc-7399-dacb-da6080000000

The overall goal of the Histology and Morphometry Core is 1) to provide a common facility and expertise for the broad spectrum of morphologic studies that may be required for interpretation of studies of various models of kidney disease and their response to interventions; 2) to provide tissue samples from existing archival specimens from various mouse and rat kidney disease models that may be used for exploration and characterization of expression patterns of various novel target molecules; and 3) to develop and enhance existing morphologic techniques to improve the ability of center investigators to localize specific molecules and tissue sections, and to interpret their significance based on the spatial localization and relationship to patterns of injury.

Proper citation: Vanderbilt Mouse Kidney Histology and Morphometry Core (RRID:SCR_010192) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/genetics/dnaseq/index.shtml

Core facility that provides the following services: Large sequencing project support, Sanger sequencing service, High throughput DNA sequencing, Ion Torrent Personal Genome Machine sequencing, Template preparation and purification, Roche 454 sequencing, Sequence analysis and database search support, Construction of targeting vector for gene targeting, Genotyping and Fragment Analysis service, Molecular biology services, Mouse genotyping, and Ion Personal Genome Machine sequencing data analysis. The DNA Sequencing Facility provides long read, automated Sanger sequencing; microsatellite-based genotyping and fragment analysis; plasmid and BAC DNA preparation and purification; and related molecular biological services including PCR, cloning, sub-cloning, site-directed mutagenesis, and preparation of targeting vectors for gene targeting in mice. Core also provides services and support for analysis and interpretation of sequence data as well as the design of approaches to complex sequencing projects. For the last four years the facility has been providing Roche 454 sequencing service that includes library preparation, emulsion PCR and pyrosequencing for both genomic DNA and amplicons.

Proper citation: University of Pennsylvania Genomics Analysis Core (RRID:SCR_011061) Copy   

•   Source: SciCrunch Registry

http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html

Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.

Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-dd9e-c2d6-8fa3-ce9080000000

The SYNERGY Clinical Research Unit (CRU) is an outpatient research support unit that offers investigators a full array of services for the conduct of clinical research. The CRU is available to any Dartmouth faculty or researcher wishing to access dedicated space and staff resources for the efficient conduct of clinical research.

Proper citation: Dartmouth SYNERGY Clinical Research Unit (RRID:SCR_005645) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e19f-9e69-d807-77a880000000

The molecular lab at Weld Hill is well equipped for modern molecular studies, from RNA expression studies to phylogenetic analyses.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Molecular Lab (RRID:SCR_004781) Copy   

•   Source: SciCrunch Registry

http://hunter-cuny.eagle-i.net/i/00000136-7eb5-5555-949b-425080000000

Core facility that provides the following services: Training Service, TEM Analysis Service. ?The Nanoscale Analytical Facility is equipped with Jeol 2100 EDAX operated at 200kV. Nanomaterial containing samples of inorganic as well as organic building blocks, macromolecular constructs, metallic nanoparticles, metal oxide nano-powders are often imaged.

Proper citation: Hunter Nanoscale Analytical Facility (RRID:SCR_005617) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-6e00-af62-55da-381e80000000

Core facility that provides the following services: DNA analysis - Affymetrix GeneChip arrays service, DNA analysis - Illumina infinium whole genome genotyping service, DNA analysis - custom content genotyping service, RNA Analysis - Affymetrix gene expression service, RNA Analysis - Illumina Gene Expression service, RNA Analysis - Illumina whole-genome DASL service. The Genetic Analysis Platform collaborates with scientists at the Broad and across the world to identify and characterize patterns of genetic variation and gene expression. These patterns can yield a deeper understanding of how genetic factors influence disease risk and treatment outcomes in a wide range of human diseases, including type 2 diabetes, Crohn''s disease, schizophrenia, and cancer, among many others. Over the past several years, the platform has been a leading contributor to major projects such as the International Haplotype Map Project, The Cancer Genome Atlas, the 1,000 Genomes Project, the Genes and Environment Initiative, and served as a national genotyping center under a NIH/NCRR program. Genetic Analysis Platform (GAP) scientists are experts in a wide range of genomic technologies and technology platforms, including genotyping, gene expression and directed resequencing, and routinely apply these technologies to studies of both human and non-human samples. In addition, teams of platform researchers work to test out emerging genetic technologies, develop informatics tools and infrastructure to enhance scientific research, and coordinate large-scale projects involving collaborators both within and beyond the Broad.

Proper citation: Broad Genetic Analysis Platform (RRID:SCR_009690) Copy   

•   Source: SciCrunch Registry

http://cau.eagle-i.net/i/00000135-abea-80e6-ecf8-187780000000

In CCRTD, we provide excellent support for Cell Biology research and advanced cell visualization applications. We have complete facilities for cell growth, handling, and storage. Cell Culture Facility maintains Cell Storage Cryo Tanks with uninterruptable liquid nitrogen supply and two separate Cell Culture rooms fully equipped with eight temperature and CO2-controlled Cell Growth Incubators, two Biological Safety Cabinets, Fluorescence-Activated Cell Sorter (FACS), two late model Inverted Digitized Microscope (Zeiss), one of which is fluorescence-enabled and possesses Z-stacking and live cell imaging capabilities, automated Cell Counter (Nexcelom Bioscience), and refrigerated storage for media and cell culture reagents.

Proper citation: CAU CCRTD-Cell Biology (RRID:SCR_009691) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60a7-d769-c437-ff0b80000000

The BWH-BRI Antibody Core Facility provides high quality, purified monoclonal antibodies to the BWH research community. Because the antibodies are made in-house and require no shipping, they are available at a cost substantially lower than that of commercial vendors. Antibodies are of standardized quality and are available in two convenient aliquots: 500ugs and 10mgs. The Core maintains an inventory of commonly used antibodies, which allows orders to be filled quickly.

Proper citation: BWH-BRI Antibody Core Facility (RRID:SCR_009689) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2511-e97c-5617-794280000000

Core facility that provides the following services: ES cell transfection (electroporation), Thawing/expansion of targeted ES cells, Microinjection of ES cells into blastocysts, Microinjection of DNA constructs into egg pronuclei for generating transgenic mice, Microinjection of BAC DNAs, DNA injection and microdissection, Lentiviral transgenics service, Injection of induced pluripotent stem cells for testing totipotency, Tail biopsy service, Breeding services, Mouse manipulation consultation. The Brigham & Women''s Hospital Transgenic Core Facility provides services for generating transgenic and knockout mice. Established in 1992, the BWH Core Facility has been providing gene targeting and microinjection services using state-of-the-art facilities and equipment. Dr. Lina Du, formerly a plastic surgeon in Beijing and an expert in microvascular surgery, performs both blastocyst and pronuclear injections. She has over 15 years of experience in embryo manipulation and the generation transgenic mice. The Core Facility has all of the equipment necessary for generation of transgenic mice including a Nikon Diaphot microscope equipped with Nomarski Optics and Narishige micromanipulators for microinjections, Nikon surgical microscopes for egg isolation ad transfer, a sutter needle puller and a de Fonbrune microforge. The facility maintains mice necessary for egg donors, egg recipients, and vasectomized males. This is a non-profit facility and charges are based upon anticipated mouse costs, maintenance of mice and equipment, and purchase of necessary surgical supplies and chemicals. The ES cell culture service has been offered for 6 years. Our staff carries out electroporation of targeting vectors into ES cells and provides investigators with DNA to identify ES cells carrying the desired recombination events. Then they expand the appropriate ES Cells for microinjection into blastocysts by the BWH Transgenic Core.

Proper citation: BWH Transgenic Core Facility (RRID:SCR_009688) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c4-1614-db6e-7a3f80000000

Core facility that provides the following services: Magnetic resonance spectrometer training service, Magnetic Resonance Instrument Access. Welcome to the Magnetic Resonance Facility of the Department of Chemistry and Chemical Biology, Harvard University, in the Laukien-Purcell Instrumentation Center.

Proper citation: Harvard FAS Magnetic Resonance Laboratory (RRID:SCR_008476) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-438e-1d98-3e3e-48fb80000000

Core facility that provides the following services: Sorting or analysis with operator service, Calcium flux measurements service, DNA analysis service, Cell sorting service.

This lab''s mission is to provide high standard cell sorting and analysis services to the research community at the Brigham and Women?s Hospital and the Longwood Medical area.

Proper citation: BWH Flow Cytometry Core Laboratory (RRID:SCR_009683) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-654b-2967-c437-ff0b80000000

Core facility that provides the following services: Fluorescence in situ hybridization.

The CytoGenomics Core provides an invaluable technical resource to the investigators of the BWH, MGH, and affiliated institutions. Services are also available to external academic and commercial laboratories; these should contact us via our website for sample submission and pricing. Cytogenetic studies can provide insight into regions of the genome that are pathogenetic in various neoplasms leading to an understanding of the molecular pathways participating in the biology of cancer. It is appropriate to consider cytogenetics as a fundamental adjunct to a variety of investigations underway, including basic and clinical research. For example, a rather simple cytogenetic analysis of mouse ES cells to determine ploidy prior to injections into blastulas leads to a greater success rate in establishing founders for knock-out and knock-in experiments. The primary chromosomal assignment of a gene by a FISH experiment may lead to correlation of a disease with that gene. Other cytogenetic studies may be important in establishing a diagnosis for correlation with clinical outcome. The advent of molecular probes for FISH analysis has facilitated cytogenetic studies in the mouse, and other model organisms and this Core aggressively implements such technologies. In addition to state-of-the-art analyses for human samples, the BWH CytoGenomics Core also performs routine mouse karyotyping and a variety of other molecular cytogenetic analyses, services not easily obtainable elsewhere.

Proper citation: BWH CytoGenomics (RRID:SCR_009681) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-64ed-0030-c437-ff0b80000000

Biostatistics support is available to investigators in the Brigham and Women''s and Harvard Medical research community for statistical consulting on issues such as study design and data analysis for manuscripts and grant applications. Resources are limited, so planning ahead is essential. The Biostatistics Consulting Service is part of the Biostatistics Core of the BWH Center for Clinical Investigation (CCI).

Proper citation: BWH Biostatistics Center (RRID:SCR_009680) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/cellbio.html

Core that gives support including experimental design, islet isolation, and performance of and training in an expansive range of assays for physiological and morphometric assessment of pancreatic islet function and growth. It contributes to the basic and translational research activities of the Institute of Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine of the University of Pennsylvania. Its services include perform individual islet and single cell fluorescence imaging, respirometry with islet batches using a Seahorse Extracellular Flux Analyzer, perifusion coupled with respirometry, and closed respirometry experiments for our investigators.

Proper citation: University of Pennsylvania School of Medicine Penn Diabetes Research Center Pancreatic Islet Cell Biology Core Facility (RRID:SCR_008265) Copy   

•   Source: SciCrunch Registry