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http://code.google.com/p/crop-tingchenlab/

A clustering tool designed mainly for Metagenomics studies, which clusters 16S rRNA sequences into Operational Taxonomic Units (OTU). By using a Gaussian Mixture model, CROP can automatically determine the best clustering result for 16S rRNA sequences at different phylogenetic levels without setting a hard cutoff threshold as hierarchical clustering does. Yet, at the same time, it is able to manage large datasets and to overcome sequencing errors.

Proper citation: CROP (RRID:SCR_006916) Copy   

•   Source: SciCrunch Registry

http://math.mcb.berkeley.edu/~meromit/MetMap/

A computational pipeline for the analysis of MethylSeq experiments., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: MetMap (RRID:SCR_006954) Copy   

•   Source: SciCrunch Registry

http://bowtie-bio.sourceforge.net/myrna/index.shtml

A cloud computing tool for calculating differential gene expression in large RNA-seq datasets. It uses Bowtie for short read alignment and R/Bioconductor for interval calculations, normalization, and statistical testing. These tools are combined in an automatic, parallel pipeline that runs in the cloud (Elastic MapReduce in this case) on a local Hadoop cluster, or on a single computer, exploiting multiple computers and CPUs wherever possible.

Proper citation: Myrna (RRID:SCR_006951) Copy   

•   Source: SciCrunch Registry

https://code.google.com/p/swdmr/

A free software using a sliding-window approach to identify differentially methylated regions (DMR) from whole-genome bisulfite sequencing.

Proper citation: swDMR (RRID:SCR_007316) Copy   

•   Source: SciCrunch Registry

http://web.bioinformatics.ic.ac.uk/geb/

A Java application developed to visualise distribution of genomic features in high resolution.

Proper citation: GEB (RRID:SCR_007395) Copy   

•   Source: SciCrunch Registry

http://www.thebiogrid.org/

Curated protein-protein and genetic interaction repository of raw protein and genetic interactions from major model organism species, with data compiled through comprehensive curation efforts.

Proper citation: Biological General Repository for Interaction Datasets (BioGRID) (RRID:SCR_007393) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/taipan/

A fast hybrid short-read assembly tool.

Proper citation: Taipan (RRID:SCR_007330) Copy   

•   Source: SciCrunch Registry

http://bmserver.sce.ntu.edu.sg/INVERTER/

Software for a de novo exact match tandem repeat finder which main advantage is without the need to specify either the pattern or a particular pattern size, integrated with a data visualization tool and has a built-in user-friendly Graphical User Interface.

Proper citation: INVERTER (RRID:SCR_007956) Copy   

•   Source: SciCrunch Registry

http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/

Allow the high-performance display of next-generation sequencing experiment results in the UCSC Genome Browser.

Proper citation: BigWig and BigBed (RRID:SCR_007708) Copy   

•   Source: SciCrunch Registry

https://code.google.com/p/highssr/

Software that predicts microsatellites with Tandem Repeats Finder (TRF).

Proper citation: HighSSR (RRID:SCR_007949) Copy   

•   Source: SciCrunch Registry

http://genotan.sourceforge.net/

A free software tool to identify length variation of microsatellites from short sequence reads.

Proper citation: GenoTan (RRID:SCR_007935) Copy   

•   Source: SciCrunch Registry

http://smithlab.usc.edu/histone/rseg/

Software package aimed to analyze ChIP-Seq data, especially for identifying genomic regions and their boundaries marked by diffusive histone modification markers, such as H3K36me3 and H3K27me3.

Proper citation: RSEG (RRID:SCR_007695) Copy   

•   Source: SciCrunch Registry

http://www.ebi.ac.uk/huber-srv/hilbert/

Software tool that allows to display very long data vectors in a space-efficient manner, allowing the user to visually judge the large scale structure and distribution of features simultaneously with the rough shape and intensity of individual features.

Proper citation: HilbertVis (RRID:SCR_007862) Copy   

•   Source: SciCrunch Registry

http://brig.sourceforge.net/

A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data.

Proper citation: BRIG (RRID:SCR_007802) Copy   

•   Source: SciCrunch Registry

http://web.bioinformatics.cicbiogune.es/AM/AnnotationModules.php

A tool for finding significant combinations of multisource annotations in gene lists.

Proper citation: Annotation-Modules (RRID:SCR_008025) Copy   

•   Source: SciCrunch Registry

http://biq-analyzer-ht.bioinf.mpi-inf.mpg.de/

Software that currently allows to process an amount of bisulfite sequencing reads obtained in one or several bisulfite sequencing experiments.

Proper citation: BiQAnalyzer HT (RRID:SCR_008045) Copy   

•   Source: SciCrunch Registry

http://erlichlab.wi.mit.edu/lobSTR/

A software tool for profiling Short Tandem Repeats (STRs) from high throughput sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: lobSTR (RRID:SCR_008030) Copy   

•   Source: SciCrunch Registry

http://drive5.com/usearch/manual/uchime_algo.html

An algorithm for detecting chimeric sequences.

Proper citation: UCHIME (RRID:SCR_008057) Copy   

•   Source: SciCrunch Registry

http://cran.r-project.org/web/packages/MetaQC/

Software for quality control and diagnosis for microarray meta-analysis. Quantitative quality control measures include: (1) internal homogeneity of co-expression structure among studies (internal quality control; IQC); (2) external consistency of co-expression structure correlating with pathway database (external quality control; EQC); (3) accuracy of differentially expressed gene detection (accuracy quality control; AQCg) or pathway identification (AQCp); (4) consistency of differential expression ranking in genes (consistency quality control; CQCg) or pathways (CQCp). For each quality control index, the p-values from statistical hypothesis testing are minus log transformed and PCA biplots were applied to assist visualization and decision. Results generate systematic suggestions to exclude problematic studies in microarray meta-analysis and potentially can be extended to GWAS or other types of genomic meta-analysis. The identified problematic studies can be scrutinized to identify technical and biological causes (e.g. sample size, platform, tissue collection, preprocessing etc) of their bad quality or irreproducibility for final inclusion / exclusion decision.

Proper citation: MetaQC (RRID:SCR_006000) Copy   

•   Source: SciCrunch Registry

http://www.bioconductor.org/packages/devel/bioc/html/deepSNV.html

Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants).

Proper citation: deepSNV (RRID:SCR_006214) Copy   

•   Source: SciCrunch Registry