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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
LegumeIP
 
Resource Report
Resource Website
10+ mentions
LegumeIP (RRID:SCR_008906) LegumeIP analysis service resource, service resource, production service resource, database, data analysis service, data or information resource LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression. gene function, genome evolution, legume, gene, genome, plant, genomics, transcriptomic, gene annotation, gene family, synteny, gene expression, blast, genomic sequence, microarray, rna-seq, comparative genomics, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: UniProt
is related to: InterProScan
is related to: Gene Ontology
is related to: KEGG
has parent organization: Samuel Roberts Noble Foundation
Samuel Roberts Noble Foundation ;
NSF ABI-0960897
PMID:22110036 biotools:legumeip, nlx_151455 https://bio.tools/legumeip SCR_008906 LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes, LegumeIP - An Integrative Platform to Study Gene Function and Genome Evolution in Legumes 2026-02-12 09:44:43 19
WikiPathways
 
Resource Report
Resource Website
1000+ mentions
WikiPathways (RRID:SCR_002134) data or information resource, database, service resource Open and collaborative platform dedicated to curation of biological pathways. Each pathway has dedicated wiki page, displaying current diagram, description, references, download options, version history, and component gene and protein lists. Database of biological pathways maintained by and for scientific community. database, knowledge environment resource, image, web service, biological pathway, diagram description, reference, pathway, FASEB list is used by: NIF Data Federation
is used by: Open PHACTS
is related to: PharmGKB
is related to: Reactome
is related to: NetPath
is related to: ConsensusPathDB
is related to: NCBI BioSystems Database
is related to: WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
has parent organization: University of California at San Francisco; California; USA
has parent organization: Maastricht University; Maastricht; Netherlands
NIH ;
Netherlands Bioinformatics Centre ;
Google Summer of Code program ;
NWO - Netherlands Organization for Scientific Research ;
NIGMS GM080223;
NIGMS R01 GM100039
PMID:22096230
PMID:18651794
Free, Freely available nif-0000-20925 SCR_002134 Wiki Pathways 2026-02-12 09:43:18 1696
RootTrace
 
Resource Report
Resource Website
1+ mentions
RootTrace (RRID:SCR_015585) software resource, software application, data analysis software, data processing software Software tool which allows the automatic and high throughput measure of root length, as well as extra associated measures such as curvature. The user must supply start points for each root, and exemplar patches of nearby background. The software will then trace the main root to the tip, in every image in a timeseries, and record the results. root length, root measurement, plant root, root bioinformatics Available for download SCR_015585 2026-02-12 09:46:16 3
GeneMANIA
 
Resource Report
Resource Website
1000+ mentions
GeneMANIA (RRID:SCR_005709) GeneMANIA analysis service resource, software resource, service resource, production service resource, database, data analysis service, data or information resource Data analysis service to predict the function of your favorite genes and gene sets. Indexing 1,421 association networks containing 266,984,699 interactions mapped to 155,238 genes from 7 organisms. GeneMANIA interaction networks are available for download in plain text format. GeneMANIA finds other genes that are related to a set of input genes, using a very large set of functional association data. Association data include protein and genetic interactions, pathways, co-expression, co-localization and protein domain similarity. You can use GeneMANIA to find new members of a pathway or complex, find additional genes you may have missed in your screen or find new genes with a specific function, such as protein kinases. Your question is defined by the set of genes you input. If members of your gene list make up a protein complex, GeneMANIA will return more potential members of the protein complex. If you enter a gene list, GeneMANIA will return connections between your genes, within the selected datasets. GeneMANIA suggests annotations for genes based on Gene Ontology term enrichment of highly interacting genes with the gene of interest. GeneMANIA is also a gene recommendation system. GeneMANIA is also accessible via a Cytoscape plugin, designed for power users. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, association data, protein interaction, genetic interaction, pathway, co-expression, co-localization, protein, software library, statistical analysis, term enrichment, analysis, browser, gene ontology, gene predicting, gene prioritization, database or data warehouse, other analysis, interaction browser, protein-protein interaction, interaction, FASEB list is listed by: Gene Ontology Tools
is related to: Cytoscape
is related to: Gene Ontology
is related to: PSICQUIC Registry
has parent organization: University of Toronto; Ontario; Canada
Genome Canada ;
Ontario Ministry of Research and Innovation 2007-OGI-TD-05
PMID:20576703
PMID:18613948
PMID:20926419
Open unspecified license, Free for academic use nlx_149159, r3d100013978 https://doi.org/10.17616/R31NJNA2 SCR_005709 2026-02-12 09:44:13 3358
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
 
Resource Report
Resource Website
100+ mentions
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool (RRID:SCR_006848) GOrilla service resource, analysis service resource, production service resource, data analysis service A tool for identifying and visualizing enriched GO terms in ranked lists of genes. It can be run in one of two modes: * Searching for enriched GO terms that appear densely at the top of a ranked list of genes or * Searching for enriched GO terms in a target list of genes compared to a background list of genes. gene, genetic, ontology, ontology or annotation visualization, statistical analysis, term enrichment, visualization, analysis, protein is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
European Union FP6 ;
Yeshaya Horowitz Association
PMID:19192299 Acknowledgement requested, Free, Public nlx_80425, OMICS_02282 SCR_006848 Gene Ontology enRIchment anaLysis and visuaLizAtion tool, GOrilla: Gene Ontology Enrichment Analysis Visualization Tool 2026-02-12 09:44:28 492
GeneTrail
 
Resource Report
Resource Website
100+ mentions
GeneTrail (RRID:SCR_006250) GeneTrail service resource, analysis service resource, production service resource, data analysis service A web-based application that analyzes gene sets for statistically significant accumulations of genes that belong to some functional category. Considered category types are: KEGG Pathways, TRANSPATH Pathways, TRANSFAC Transcription Factor, GeneOntology Categories, Genomic Localization, Protein-Protein Interactions, Coiled-coil domains, Granzyme-B clevage sites, and ELR/RGD motifs. The web server provides two statistical approaches, "Over-Representation Analysis" (ORA) comparing a reference set of genes to a test set, and "Gene Set Enrichment Analysis" (GSEA) scoring sorted lists of genes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. pathway, microarray, enrichment, genomic, proteomic, function, transcription factor, genomic localization, protein-protein interaction, coiled-coil domain, granzyme-b clevage site, motif, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
is related to: TRANSPATH
is related to: TRANSFAC
is related to: Gene Ontology
has parent organization: Saarland University; Saarbrucken; Germany
PMID:17526521 THIS RESOURCE IS NO LONGER IN SERVICE biotools:genetrail, OMICS_02236 https://bio.tools/genetrail SCR_006250 2026-02-12 09:44:12 106
AthaMap
 
Resource Report
Resource Website
10+ mentions
AthaMap (RRID:SCR_006717) data or information resource, database Genome wide map of putative transcription factor binding sites in Arabidopsis thaliana genome.Data in AthaMap is based on published transcription factor (TF) binding specificities available as alignment matrices or experimentally determined single binding sites.Integrated transcriptional and post transcriptional data.Provides web tools for analysis and identification of co-regulated genes. Provides web tools for database assisted identification of combinatorial cis-regulatory elements and the display of highly conserved transcription factor binding sites in Arabidopsis thaliana. gene, arabidopsis thaliana, binding site, genome, transcription factor, small rna binding site, small rna, rna, microrna, cis-regulatory element, post-transcriptional regulation, FASEB list is listed by: OMICtools
is listed by: bio.tools
has parent organization: Technical University of Braunschweig; Braunschweig; Germany
PMID:22800758
PMID:21177332
PMID:18842622
PMID:17148485
PMID:16922688
PMID:15980498
PMID:14681436
Free, Freely available nif-0000-02583, biotools:athamap, OMICS_00549, nif-0000-20814, SCR_013106 https://bio.tools/athamap SCR_006717 Arabidopsis thaliana Map 2026-02-12 09:44:18 48
PlantCyc
 
Resource Report
Resource Website
1000+ mentions
PlantCyc (RRID:SCR_002110) PMN data or information resource, portal, project portal, database Multi species reference database. Comprehensive plant biochemical pathway database, containing curated information from literature and computational analyses about genes, enzymes, compounds, reactions, and pathways involved in primary and secondary metabolism. enzyme, gene, biochemical pathway, compound, metabolism, plant metabolic, reaction, database is listed by: Plant Metabolic Network
has parent organization: Carnegie Institution for Science
NSF 1026003;
NSF 0640769
PMID:20522724 Free, Available for download, Freely available , nif-0000-20890, nlx_15806 plant http://www.plantcyc.org/ SCR_002110 2026-02-12 09:43:18 3633
Mikado
 
Resource Report
Resource Website
50+ mentions
Mikado (RRID:SCR_016159) source code, software resource Mikado is a lightweight Python3 pipeline whose purpose is to facilitate the identification of expressed loci from RNA-Seq data * and to select the best models in each locus. annotation, rna-seq, genomics, transcriptomics is related to: Portcullis BBSRC BB/J004669/1;
BBSRC BB/J010375/1;
BBSRC BB/CSP17270/1;
BBSRC BB/CCG1720/1
DOI:10.1101/216994 Free, Available for download http://mikado.readthedocs.io/ SCR_016159 2026-02-12 09:46:44 82
PLAN2L
 
Resource Report
Resource Website
PLAN2L (RRID:SCR_013346) PLAN2L data or information resource, database, service resource A web-based online search system that integrates text mining and information extraction techniques to access systematically information useful for analyzing genetic, cellular and molecular aspects of the plant model organism Arabidopsis thaliana. The system facilitates a more efficient retrieval of information relevant to heterogeneous biological topics, from implications in biological relationships at the level of protein interactions and gene regulation, to sub-cellular locations of gene products and associations to cellular and developmental processes, i.e. cell cycle, flowering, root, leaf and seed development. Beyond single entities, also predefined pairs of entities can be provided as queries for which literature-derived relations together with textual evidences are returned. text mining, bio-entity relation extraction, literature, information extraction, cell cycle, regulation, protein interaction, cellular location, flowering, leave, root, seed, gene, normalization, interaction, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Spanish National Cancer Research Center
PMID:19520768 OMICS_01192, biotools:plan2l https://bio.tools/plan2l SCR_013346 PLAN2L: Plant Annotation to Literature, Plant annotation to literature 2026-02-12 09:45:49 0
TAIR
 
Resource Report
Resource Website
5000+ mentions
TAIR (RRID:SCR_004618) TAIR, AGI LocusCode data or information resource, database Database of genetic and molecular biology data for the model higher plant Arabidopsis thaliana. Data available includes the complete genome sequence along with gene structure, gene product information, metabolism, gene expression, DNA and seed stocks, genome maps, genetic and physical markers, publications, and information about the Arabidopsis research community. Gene product function data is updated every two weeks from the latest published research literature and community data submissions. Gene structures are updated 1-2 times per year using computational and manual methods as well as community submissions of new and updated genes. TAIR also provides extensive linkouts from data pages to other Arabidopsis resources. The data can be searched, viewed and analyzed. Datasets can also be downloaded. Pages on news, job postings, conference announcements, Arabidopsis lab protocols, and useful links are provided. genetic, molecular biology, gene, genome, structure, product, metabolism, gene expression, dna, seed stock, genome map, genetic marker, physical marker, genome sequence, gene product, blast, experimental protocol, gold standard is used by: NIF Data Federation
is listed by: OMICtools
is listed by: re3data.org
is listed by: DataCite
is related to: AmiGO
is related to: Saskatoon Arabidopsis T-DNA mutant population SK Collection
is related to: CLENCH
has parent organization: Carnegie Institution for Science
is parent organization of: TAIR Keyword Browser
is parent organization of: PubSearch
NSF DBI-0850219;
corporate and nonprofit organizations
PMID:22140109
PMID:17986450
PMID:12444417
PMID:12519987
PMID:18287693
r3d100010185, nlx_61477, OMICS_01662 https://doi.org/10.17616/R3QW21 SCR_004618 AGI LocusCode, The Arabidopsis Information Resource 2026-02-11 10:57:00 7421
Organelle DB
 
Resource Report
Resource Website
1+ mentions
Organelle DB (RRID:SCR_007837) Organelle DB data repository, service resource, d spatial image, storage service resource, database, data or information resource, image collection Database of organelle proteins, and subcellular structures / complexes from compiled protein localization data from organisms spanning the eukaryotic kingdom. All data may be downloaded as a tab-delimited text file and new localization data (and localization images, etc) for any organism relevant to the data sets currently contained in Organelle DB is welcomed. The data sets in Organelle DB encompass 138 organisms with emphasis on the major model systems: S. cerevisiae, A. thaliana, D. melanogaster, C. elegans, M. musculus, and human proteins as well. In particular, Organelle DB is a central repository of yeast protein localization data, incorporating results from both previous and current (ongoing) large-scale studies of protein localization in Saccharomyces cerevisiae. In addition, we have manually curated several recent subcellular proteomic studies for incorporation in Organelle DB. In total, Organelle DB is a singular resource consolidating our knowledge of the protein composition of eukaryotic organelles and subcellular structures. When available, we have included terms from the Gene Ontologies: the cellular component, molecular function, and biological process fields are discussed more fully in GO. Additionally, when available, we have included fluorescent micrographs (principally of yeast cells) visualizing the described protein localization. Organelle View is a visualization tool for yeast protein localization. It is a visually engaging way for high school and undergraduate students to learn about genetics or for visually-inclined researchers to explore Organelle DB. By revealing the data through a colorful, dimensional model, we believe that different kinds of information will come to light. gene, fly, vertebrate, human, mouse, plant, worm, yeast, protein, k-12, organelle, protein localization, function, subcellular structure, protein complex, sequence, annotation, micrograph, visualization, data analysis service is related to: Gene Ontology
has parent organization: University of Michigan; Ann Arbor; USA
American Cancer Society Research Scholar Grant RSG-06-179-01-MBC;
March of Dimes Basil O'Connor Starter Scholar Research award 5-FY05-1224;
NSF DBI-0543017
PMID:17130152
PMID:15608270
Free, Acknowledgement requested nif-0000-03226 SCR_007837 Organelle DB: A Database of Organelles and Protein Complexes 2026-02-12 09:44:36 7
MitoMiner
 
Resource Report
Resource Website
50+ mentions
MitoMiner (RRID:SCR_001368) data or information resource, database A database of mitochondrial proteomics data. It includes two sets of proteins: the MitoMiner Reference Set, which has 10477 proteins from 12 species; and MitoCarta, which has 2909 proteins from mouse and human mitochondrial proteins. MitoMiner provides annotation from the Gene Ontology (GO) and UniProt databases. This reference set contains all proteins that are annotated by either of these resources as mitochondrial in any of the species included in MitoMiner. MitoMiner data via is available via Application Programming Interface (API). The client libraries are provided in Perl, Python, Ruby and Java. mitochondrion, proteomics, function, homolog, proteome, protein expression, mass-spectrometry, protein, metabolism, green fluorescent protein tag, ortholog, FASEB list uses: HomoloGene
uses: UniProt
uses: KEGG
uses: OMIM
uses: The Human Protein Atlas
uses: Gene Ontology
MRC PMID:22121219
PMID:19208617
Public, Acknowledgement requested, Code: nlx_152504 SCR_001368 MitoMiner - A database of the mitochondrial proteome 2026-02-11 10:56:12 76
Spliceosome Database
 
Resource Report
Resource Website
10+ mentions
Spliceosome Database (RRID:SCR_002097) Spliceosome Database data or information resource, database A database of proteins and RNAs that have been identified in various purified splicing complexes. Various names, orthologs and gene identifiers of spliceosome proteins have been cataloged to navigate the complex nomenclature of spliceosome proteins. Links to gene and protein records are also provided for the spliceosome components in other databases. To navigate spliceosome assembly dynamics, tools were created to compare the association of spliceosome proteins with complexes that form at specific stages of spliceosome assembly based on a compendium of mass spectrometry experiments that identified proteins in purified splicing complexes. splicing, mass spectrometry, protein, rna, complex, spliceosome, small nuclear rna, structure, dynamics, ortholog, gene is listed by: OMICtools
has parent organization: University of California at Santa Cruz; California; USA
PMID:23118483 Free, Freely available OMICS_01891 SCR_002097 Spliceosome Database - A source of information for the SLPICEOSOME: The large ribonucleoprotein complex responsible for pre-mRNA splicing, Spliceosome Component Database 2026-02-11 10:56:23 11
GermOnline
 
Resource Report
Resource Website
10+ mentions
GermOnline (RRID:SCR_002807) GermOnline data or information resource, database Cross-species microarray expression database focusing on high-throughput expression data relevant for germline development, meiosis and gametogenesis as well as the mitotic cell cycle. The database contains a unique combination of information: 1) High-throughput expression data obtained with whole-genome high-density oligonucleotide microarrays (GeneChips). 2) Sample annotation (mouse over the sample name and click on it) using the Multiomics Information Management and Annotation System (MIMAS 3.0). 3) In vivo protein-DNA binding data and protein-protein interaction data (available for selected species). 4) Genome annotation information from Ensembl version 50. 5) Orthologs are identified using data from Ensembl and OMA and linked to each other via a section in the report pages. The portal provides access to the Saccharomyces Genomics Viewer (SGV) which facilitates online interpretation of complex data from experiments with high-density oligonucleotide tiling microarrays that cover the entire yeast genome. The database displays only expression data obtained with high-density oligonucleotide microarrays (GeneChips)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. fertility, development, germline, microarray, annotation, in vivo, protein-dna binding, protein-protein interaction, genome, ortholog, high-density oligonucleotide microarray, gene expression, genome annotation, gene orthology, genechip, tiling array, development, meiosis, gametogenesis, mitotic cell cycle, data set, data repository, bio.tools is listed by: 3DVC
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Ensembl
is related to: OMA Browser
has parent organization: National Institute of Health and Medical Research; Rennes; France
Swiss Institute of Bioinformatics ;
bioinformatics platform of Biogenouest ;
National Institute of Health and Medical Research; Rennes; France ;
University of Rennes 1; Rennes; France
PMID:21149299 THIS RESOURCE IS NO LONGER IN SERVICE biotools:germonline, nif-0000-02906, r3d100010248 https://bio.tools/germonline
https://doi.org/10.17616/R37K5Q
SCR_002807 2026-02-11 10:56:35 17
MIPS Arabidopsis thaliana Database
 
Resource Report
Resource Website
1+ mentions
MIPS Arabidopsis thaliana Database (RRID:SCR_003088) data or information resource, database Repository for genome sequence data in the European Scientists Sequencing Arabidopsis (ESSA) project, part of the Arabidopsis Genome Initiative. It is moving towards becoming an integrated biological knowledge resource by integrating diverse data, tools, query and visualization capabilities. The aim is to create a comprehensive resource for Arabidopsis as a model that can then be used to transfer knowledge onto sequences from other species, including crop plants. plant genome, plant database, plant genome database PMID:11752263 Free, Available for download, Freely available nif-0000-03104 https://pmc.ncbi.nlm.nih.gov/articles/PMC99069/ SCR_003088 MAtDB 2026-02-11 10:56:37 1
HINT
 
Resource Report
Resource Website
100+ mentions
HINT (RRID:SCR_002762) HINT data or information resource, database A database of high-quality protein-protein interactions in different organisms. protein-protein interaction, bio.tools, FASEB list is used by: Mutation Annotation and Genomic Interpretation
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Cornell University; New York; USA
PMID:22846459 Free, Freely available, Available for download OMICS_02898, biotools:hint https://bio.tools/hint SCR_002762 High-quality INTeractomes 2026-02-11 10:56:32 306
PPDB: Plant Promoter Database
 
Resource Report
Resource Website
PPDB: Plant Promoter Database (RRID:SCR_003395) PPDB data or information resource, database A plant promoter database that provides information on transcription start sites (TSSs), core promoter structure and regulatory element groups (REGs) as putative and comprehensive transcriptional regulatory elements. Microarray data-based predictions have been appended as REG annotations which inform their putative physiological roles. gene, transcription start site, promoter structure, promoter, regulatory element group, homolog is listed by: OMICtools
has parent organization: Gifu University; Gifu; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:24194597
PMID:17947329
Free, Available for download, Freely available nif-0000-03329, OMICS_01874 http://ppdb.gene.nagoya-u.ac.jp/cgi-bin/index.cgi SCR_003395 Plant Promoter Database 2026-02-11 10:56:40 0
CSHL - Hannon Lab
 
Resource Report
Resource Website
50+ mentions
CSHL - Hannon Lab (RRID:SCR_005982) Hannon Lab data or information resource, portal, laboratory portal, organization portal The Hannon laboratory comprises a broad spectrum of programs in small RNA biology, mammalian genetics and genomics. We study RNAi and related pathways in a wide variety of organisms to extract common themes that define both the mechanisms by which small RNAs act and the biological processes which they impact. Currently, we focus on microRNAs, endogenous siRNAs and piRNAs and their roles in gene regulation, cancer biology, stem cell biology and in defense of the genome against transposons. In collaboration with Steve Elledge (Harvard) and Scott Lowe (CSHL), we develop genome-wide shRNA tools for RNAi-based genetics in mammalian cells, and we are now producing similar collections of artificial microRNAs for Arabidopsis with Detlef Weigel (MPI), Dick McCombie (CSHL) and Rob Martienssen (CSHL) as part of the 2010 project (see 2010.cshl.edu). Our genomic efforts include the application of RNAi-based genetic screens to cancer biology and stem cells. We also make heavy use of next generation sequencing methodologies for probing small RNA populations, in part as a member of the ENCODE consortium (with Tom Gingeras, CSHL). Finally, we develop (with Dick McCombie) and apply focal re-sequencing methods for identifying disease relevant mutations, for probing the epigenetic landscape and for the study of human evolution. rnai, rna, mammal, genetics, genomics, microrna, sirna, pirna, gene regulation, cancer biology, stem cell biology, defense, genome, transposon, cancer, stem cell has parent organization: Cold Spring Harbor Laboratory nlx_151354 SCR_005982 Cold Spring Harbor Laboratory - Hannon Lab 2026-02-12 09:44:09 66
EGAN: Exploratory Gene Association Networks
 
Resource Report
Resource Website
1+ mentions
EGAN: Exploratory Gene Association Networks (RRID:SCR_008856) EGAN software resource, software application, data analysis software, data processing software Exploratory Gene Association Networks (EGAN) is a software tool that allows a bench biologist to visualize and interpret the results of high-throughput exploratory assays in an interactive hypergraph of genes, relationships (protein-protein interactions, literature co-occurrence, etc.) and meta-data (annotation, signaling pathways, etc.). EGAN provides comprehensive, automated calculation of meta-data coincidence (over-representation, enrichment) for user- and assay-defined gene lists, and provides direct links to web resources and literature (NCBI Entrez Gene, PubMed, KEGG, Gene Ontology, iHOP, Google, etc.). EGAN functions as a module for exploratory investigation of analysis results from multiple high-throughput assay technologies, including but not limited to: * Transcriptomics via expression microarrays or RNA-Seq * Genomics via SNP GWAS or array CGH * Proteomics via MS/MS peptide identifications * Epigenomics via DNA methylation, ChIP-on-Chip or ChIP-Seq * In-silico analysis of sequences or literature EGAN has been built using Cytoscape libraries for graph visualization and layout, and is comparable to DAVID, GSEA, Ingenuity IPA and Ariadne Pathway Studio. There are pre-collated EGAN networks available for human (Homo sapiens), mouse (Mus musculus), rat (Rattus norvegicus), chicken (Gallus gallus), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), nematode (Caenorhabditis elegans), mouse-ear cress (Arabidopsis thaliana), rice (Oryza sativa) and brewer's yeast (Saccharomyces cerevisiae). There is now an EGAN module available for GenePattern (human-only). Platform: Windows compatible, Mac OS X compatible, Linux compatible gene, gene association, network, protein-protein interaction, pathway, interaction, annotation, signaling pathway, enrichment, cytoscape, visualization is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: UCSF Helen Diller Family Comprehensive Cancer Center Biostatistics Core
NCI P30 CA92103 PMID:19933825 Free for academic use nlx_149222 SCR_008856 Exploratory Gene Association Networks, Exploratory Gene Association Networks (EGAN) 2026-02-12 09:44:42 8

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