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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ACCORD
 
Resource Report
Resource Website
100+ mentions
ACCORD (RRID:SCR_009015) ACCORD clinical trial, resource Study testing whether strict glucose control lowers the risk of heart disease and stroke in adults with type 2 diabetes. In addition the study is exploring: 1) Whether in the context of good glycemic control the use of different lowering lipid drugs will further improve these outcomes and 2) If strict control of blood pressure will also have additional beneficial effects on reducing cardiovascular disease. The design was a randomized, multicenter, double 2 X 2 factorial trial in 10,251 patients with type 2 diabetes mellitus. It was designed to test the effects on major CVD events of intensive glycemia control, of fibrate treatment to increase HDL-cholesterol and lower triglycerides (in the context of good LDL-C and glycemia control), and of intensive blood pressure control (in the context of good glycemia control), each compared to an appropriate control. All 10,251 participants were in an overarching glycemia trial. In addition, one 2 X 2 trial addressed the lipid question in 5,518 of the participants and the other 2 X 2 trial addressed the blood pressure question in 4,733 of the participants. The glycemia trial was terminated early due to higher mortality in the intensive compared with the standard glycemia treatment strategies. The results were published in June 2008 (N Eng J Med 2008;358:2545-59). Study-delivered treatment for all ACCORD participants was stopped on June 30, 2009, and the participants were assisted as needed in transferring their care to a personal physician. The lipid and blood pressure results (as well as the microvascular outcomes and eye substudy results) were published in 2010. All participants are continuing to be followed in a non-treatment observational study. middle adult human, late adult human, glycemic control, lowering lipid drug, blood pressure, lipid, clinical is related to: NIDDK Information Network (dkNET)
has parent organization: National Heart Lung and Blood Institute
Cardiovascular disease, Stroke, Type 2 diabetes, Diabetes, Aging NHLBI ;
NIDDK ;
NEI ;
CDC ;
NIA
PMID:23490598
PMID:23253271
PMID:23238658
PMID:22723583
PMID:22646230
nlx_152746 SCR_009015 Action to Control Cardiovascular Disease Risk in Diabetes 2026-02-14 02:07:33 173
ReBATE
 
Resource Report
Resource Website
ReBATE (RRID:SCR_017139) software resource, software toolkit Open source software Python package to compare relief based feature selection algorithms used in data mining. Used for feature selection in any bioinformatics problem with potentially predictive features and target outcome variable, to detect feature interactions without examination of all feature combinations, to detect features involved in heterogeneous patterns of association such as genetic heterogeneity . compare, relief, feature, algorithm, data, mining, variable, heterogeneous, pattern, genetic has parent organization: University of Pennsylvania; Philadelphia; USA NIAID AI116794;
NIDDK DK112217;
NIEHS ES013508;
NEI EY022300;
NHLBI HL134015;
NLM LM009012;
NLM LM010098;
NLM LM011360;
NCATS TR001263;
Warren Center for Network and Data Science
PMID:30030120 Free, Available for download, Freely available https://epistasislab.github.io/ReBATE/ SCR_017139 Relief Based Algorithm Training Environment 2026-02-14 02:07:01 0
nbdocker
 
Resource Report
Resource Website
nbdocker (RRID:SCR_017159) software resource, software application Software tool as Jupyter Notebook extension for Docker. Each Docker container encapsulates its individual computing environment to allow different programming languages and computing environments to be included in one single notebook, provides user to document code as well as computing environment. Jupyter, notebook, extension, docker, container, code, computing, environment, data is related to: University of Washington; Seattle; USA NHLBI U54 HL127624;
NIGMS R01 GM126019;
Institute of Technology at University of Washington Tacoma
DOI:10.1101/309567 Free, Available for download, Freely available https://hub.docker.com/r/biodepot/nbdocker/ SCR_017159 2026-02-14 02:07:24 0
National Gene Vector Biorepository
 
Resource Report
Resource Website
10+ mentions
National Gene Vector Biorepository (RRID:SCR_004760) NGVB core facility, access service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Archiving services, insertional site analysis, pharmacology and toxicology resources, and reagent repository for academic investigators and others conducting gene therapy research. Databases and educational resources are open to everyone. Other services are limited to gene therapy investigators working in academic or other non-profit organizations. Stores reserve or back-up clinical grade vector and master cell banks. Maintains samples from any gene therapy related Pharmacology or Toxicology study that has been submitted to FDA by U.S. academic investigator that require storage under Good Laboratory Practices. For certain gene therapy clinical trials, FDA has required post-trial monitoring of patients, evaluating clinical samples for evidence of clonal expansion of cells. To help academic investigators comply with this FDA recommendation, the NGVB offers assistance with clonal analysis using LAM-PCR and LM-PCR technology. gene therapy, clinical trial, testing, insertion site, gene, clinical, vector, cell line, pharmacology, toxicology, clonal analysis, FASEB list is related to: NIDDK Information Network (dkNET)
is related to: Phoenix
has parent organization: Indiana University School of Medicine; Indiana; USA
is parent organization of: NGVB SeqMap Database
is parent organization of: NGVB Toxicology Database
NHLBI ;
NCRR
PMID:31910049 THIS RESOURCE IS NO LONGER IN SERVICE nlx_76398 http://www.ngvl.org/
https://www.ngvbcc.org/Home.action
SCR_004760 2026-02-14 02:07:54 33
Penn machine learning benchmark repository
 
Resource Report
Resource Website
Penn machine learning benchmark repository (RRID:SCR_017138) PMLB data or information resource, data set Python wrapper for Penn Machine Learning Benchmark data repository. Large, curated repository of benchmark datasets for evaluating supervised machine learning algorithms. Part of PyPI https://pypi.org/ benchmark, suite, machine, learning, evaluation, comparison, repository, curated, dataset NIAID AI116794;
NIDDK DK112217;
NIEHS ES013508;
NEI EY022300;
NHLBI HL134015;
NLM LM009012;
NLM LM010098;
NLM LM011360;
NCATS TR001263;
Warren Center for Network and Data Science
PMID:29238404 Free, Restricted https://github.com/EpistasisLab/penn-ml-benchmarks SCR_017138 Penn Machine Learning Benchmark 2026-02-14 02:08:01 0
Human Reference Protein Interactome Project
 
Resource Report
Resource Website
10+ mentions
Human Reference Protein Interactome Project (RRID:SCR_015670) HuRI web application, portal, data or information resource, software resource, database, project portal Project portal for the Human Reference Protein Interactome Project, which aims generate a first reference map of the human protein-protein interactome network by identifying binary protein-protein interactions (PPIs). It achieves this by systematically interrogating all pairwise combinations of predicted human protein-coding genes using proteome-scale technologies. protein interactome, protein-protein interaction, ppi, pairwise combination, proteome, human reference NHGRI R01/U01HG001715;
NHGRI P50HG004233;
NHLBI U01HL098166;
NHLBI U01HL108630;
NCI U54CA112962;
NCI R33CA132073;
NIH RC4HG006066;
NICHD ARRA R01HD065288;
NICHD ARRA R21MH104766;
NICHD ARRA R01MH105524;
NIMH R01MH091350;
NSF CCF-1219007;
NSERC RGPIN-2014-03892
PMID:25416956 Freely Available, Free, Available for download SCR_015670 HuRI: The Human Reference Protein Interactome Mapping Project 2026-02-14 02:04:37 20
xHLA
 
Resource Report
Resource Website
1+ mentions
xHLA (RRID:SCR_022277) software resource, data processing software, software application Software tool for fast and accurate HLA typing from short read sequence data. Iteratively refines mapping results at amino acid level to achieve four digit typing accuracy for both class I and II HLA genes, taking only 3 min to process 30× whole genome BAM file on desktop computer. HLA typing, short read sequence data, refines mapping results, amino acid level, four digit typing accuracy NCI 5U24CA076518;
NHLBI 5U10HL069294;
Health Resources and Services Administration ;
Office of Naval Research Grants
PMID:28674023 Free, Available for download, Freely available SCR_022277 2026-02-14 02:05:22 2
LINCS Data Portal 2.0
 
Resource Report
Resource Website
1+ mentions
LINCS Data Portal 2.0 (RRID:SCR_022566) LDP v2 data or information resource, portal Primary access point for compendium of LINCS data with substantial changes in data architecture and APIs, completely redesigned user interface, and enhanced curated metadata annotations to support more advanced, intuitive and deeper querying, exploration and analysis capabilities. LINCS datasets are accessible at data point level enabling users to directly access and download any subset of signatures across entire library independent from originating source, project or assay. Newly designed query interface enables global metadata search with autosuggest across all annotations associated with perturbations, model systems, and signatures. LINCS Data Portal, Cell, molecules, drug is related to: LINCS Data Portal NHLBI U54HL127624;
BD2K-LINCS Data Coordination and Integration Center ;
NCATS U24TR002278;
NLM U01LM012630
PMID:31701147 Free, Freely available SCR_022566 Library of Integrated Network Based Cellular Signatures 2.0 2026-02-14 02:05:49 2
Body Mass Index Calculator
 
Resource Report
Resource Website
Body Mass Index Calculator (RRID:SCR_000122) BMI Calculator data analysis service, production service resource, service resource, analysis service resource Body Mass Index (BMI) for adults can be calculated using only height and weight. Body mass index (BMI) is a measure of body fat based on height and weight that applies to adult men and women. adult human, body mass, male, female is listed by: NIDDK Information Network (dkNET)
is listed by: Genetic Analysis Software
has parent organization: National Heart Lung and Blood Institute
NHLBI Free, Public nlx_152731 SCR_000122 Calculate Your Body Mass Index 2026-02-14 02:05:31 0
NeuroPedia
 
Resource Report
Resource Website
10+ mentions
NeuroPedia (RRID:SCR_001551) NeuroPedia data or information resource, database A neuropeptide encyclopedia of peptide sequences (including genomic and taxonomic information) and spectral libraries of identified MS/MS spectra of homolog neuropeptides from multiple species. proteomics, peptide, neuropeptide, mass spectrometry assay, peptide sequence, spectrum, homolog has parent organization: Center for Computational Mass Spectrometry NCRR P41-RR024851;
NIDA 5K01DA23065;
NINDS R01 NS24553;
NIDA R01 DA04271;
NIMH R01 MH077305;
NHLBI P01 HL58120
PMID:21821666 Free, Freely available nlx_152894 SCR_001551 NeuroPedia: Neuropeptide database and spectra library 2026-02-14 02:05:35 12
Nuclear Receptor Signaling Atlas
 
Resource Report
Resource Website
100+ mentions
Nuclear Receptor Signaling Atlas (RRID:SCR_003287) NURSA biomaterial supply resource, material resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on February 25, 2022.Software tool as knowledge environment resource that accrues, develops, and communicates information that advances understanding of structure, function, and role in disease of nuclear receptors (NRs) and coregulators. It specifically seeks to elucidate roles played by NRs and coregulators in metabolism and development of metabolic disorders. Includes large validated data sets, access to reagents, new findings, library of annotated prior publications in field, and journal covering reviews and techniques.As of March 20, 2020, NURSA is succeeded by the Signaling Pathways Project (SPP). nuclear receptor, coregulator, metabolism, metabolic disorder, type 2 diabetes, obesity, osteoporosis, lipid dysregulation, cardiovascular disease, oncology, regenerative medicine, environmental agent, genomics, proteomics, reagent, ligand, microarray, gene expression, data set, data analysis service, nuclear receptor signaling, signaling, high through put screening, receptor, ligand, journal, molecule, affinity purification, q-pcr, chip-chip, animal model, antibody, cell line, primer, transcriptomine, clinical trial, disease, drug, data set is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
lists: NURSA Transcriptomine
lists: STRING
lists: Nuclear Receptor Cistrome
is listed by: NIH Data Sharing Repositories
is listed by: NIDDK Research Resources
is listed by: NIDDK Information Network (dkNET)
is related to: dkCOIN
is related to: Integrated Manually Extracted Annotation
has parent organization: Baylor College of Medicine; Houston; Texas
Metabolic disorder, Type 2 diabetes mellitus, Obesity, Osteoporosis, Lipid dysregulation, Cardiovascular disease, Diabetes, Cancer NHLBI ;
NIEHS ;
NICHD ;
NIDDK DK097748
DOI:10.1101/401729 Free, Freely available nif-0000-03208 https://dknet.org/about/NURSA_Archive http://www.nursa.org SCR_003287 NURSA - Nuclear Receptor Signaling Atlas, NURSA - The Nuclear Receptor Signaling Atlas 2026-02-14 02:06:56 135
PhenoExplorer
 
Resource Report
Resource Website
PhenoExplorer (RRID:SCR_008980) PhenoExplorer data analysis service, production service resource, service resource, analysis service resource A tool for finding dbGaP studies containing phenotype variables of interest. Lack of standardization makes locating and categorizing previously measured variables difficult. This query tool for biomedical researchers is to identify studies and phenotype variables of interest. phenotype is related to: NCBI database of Genotypes and Phenotypes (dbGap)
has parent organization: University of Southern California; Los Angeles; USA
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
NHLBI 1UH2HL108780 Public, Registration required nlx_152227 SCR_008980 2026-02-14 02:06:37 0
NHLBI Exome Sequencing Project (ESP)
 
Resource Report
Resource Website
1000+ mentions
NHLBI Exome Sequencing Project (ESP) (RRID:SCR_012761) EVS data or information resource, database The goal of the project is to discover novel genes and mechanisms contributing to heart, lung and blood disorders by pioneering the application of next-generation sequencing of the protein coding regions of the human genome across diverse, richly-phenotyped populations and to share these datasets and findings with the scientific community to extend and enrich the diagnosis, management and treatment of heart, lung and blood disorders. The groups participating and collaborating in the NHLBI GO ESP include: Seattle GO - University of Washington, Seattle, WA Broad GO - Broad Institute of MIT and Harvard, Cambridge, MA WHISP GO - Ohio State University Medical Center, Columbus, OH Lung GO - University of Washington, Seattle, WA WashU GO - Washington University, St. Louis, MO Heart GO - University of Virginia Health System, Charlottesville, VA ChargeS GO - University of Texas Health Sciences Center at Houston bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University of Washington; Seattle; USA
NHLBI nlx_156901, biotools:esp, biotools:exome_variant_server https://bio.tools/esp
https://bio.tools/exome_variant_server
SCR_012761 Exome Variant Server, NHLBI GO Exome Sequencing Project (ESP) 2026-02-14 02:06:16 2137
LINCS Data Portal
 
Resource Report
Resource Website
10+ mentions
LINCS Data Portal (RRID:SCR_014939) data or information resource, portal Portal which provides a unified interface for searching LINCS dataset packages and reagents. Users can use the portal to access datasets, small molecules, cells, genes, proteins and peptides, and antibodies. portal, assay, lincs, kinome, dataset, small molecule, cell, gene, protein, peptide, and antibodies. is related to: LINCS Data Portal 2.0
has parent organization: University of Miami; Florida; USA
is parent organization of: CycIF.org
NIH Common Fund ;
NHLBI 1U01HL111561;
NHLBI 3U01HL111561-01S1;
NHLBI 3U01HL111561-02S1;
NHGRI U54HG006097;
NHGRI U54 HG006093
Freely available SCR_014939 2026-02-14 02:05:13 13
HMS LINCS Center
 
Resource Report
Resource Website
10+ mentions
HMS LINCS Center (RRID:SCR_016370) HMS LINCS data or information resource, organization portal, portal Center that is part of the NIH Library of Integrated Network-based Cellular Signatures (LINCS) Program. Its goals are to collect and disseminate data and analytical tools needed to understand how human cells respond to perturbation by drugs, the environment, and mutation. LINCS, Program, library, network, cell, signature, analysis, drugs, human, research is related to: HMS LINCS Database
has parent organization: Harvard Medical School; Massachusetts; USA
NHLBI U54 HL127365 PMID:29199020 SCR_016370 LINCS Center, Harvard Medical School LINCS Center, Harvard Medical School LINCS, Harvard Medical School (HMS) LINCS Center 2026-02-14 02:05:40 15
mgatk
 
Resource Report
Resource Website
1+ mentions
mgatk (RRID:SCR_021159) data processing software, software resource, software toolkit, software application Software python-based command line interface for processing .bam files with mitochondrial reads and generating high-quality heteroplasmy estimation from sequencing data. This package places a special emphasis on mitochondrial genotypes generated from single-cell genomics data, primarily mtscATAC-seq, but is generally applicable across other assays. processing .bam files, mitochondrial reads, heteroplasmy estimation, sequencing data, mitochondrial genotypes, mtscATAC-seq NCI F31 CA232670;
NCI R01 CA208756;
NCI P01 CA206978;
NCI U10 CA180861;
NIDDK R01 DK103794;
NHLBI R33 HL120791
DOI:10.1038/s41587-020-0645-6 Free, Available for download, Freely available SCR_021159 mitochondrial genome analysis toolkit 2026-02-14 02:05:42 2
X2K Web
 
Resource Report
Resource Website
10+ mentions
X2K Web (RRID:SCR_023624) X2K data access protocol, software resource, web service Web service to predict involvement of upstream cell signaling pathways, given signature of differentially expressed genes. Used to linking expression signatures to upstream cell signaling networks. predicts involvement of upstream cell signaling pathways, differentially expressed genes, linking expression signatures, upstream cell signaling networks, has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA NHLBI U54 HL127624;
NCI U24 CA224260;
NIH Office of the Director OT3 OD025467
PMID:29800326 Free, Freely available https://github.com/MaayanLab/x2k_web SCR_023624 eXpression2Kinases (X2K) Web 2026-02-14 02:04:58 10
Poly Peak Parser
 
Resource Report
Resource Website
1+ mentions
Poly Peak Parser (RRID:SCR_023776) data access protocol, software resource, web service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 25,2025. Web tool to parse Sanger sequencing chromatograms with double peaks into wildtype and alternative allele sequences. Used to separate chromatogram data containing ambiguous base calls into wildtype and mutant allele sequences.Used for identification of unknown indels using sanger sequencing of polymerase chain reaction products. unknown indels identification, parse Sanger sequencing chromatograms, chromatograms with double peaks, separate chromatogram data, ambiguous base calls, wildtype sequences, mutant allele sequences, alternative allele sequences, NHLBI U01HL0981;
NHLBI U01HL098188;
NHLBI 1F32HL115881
PMID:25160973 THIS RESOURCE IS NO LONGER IN SERVICE http://yosttools.genetics.utah.edu/PolyPeakParser/ SCR_023776 2026-02-14 02:05:00 5
Atherosclerosis Risk in Communities
 
Resource Report
Resource Website
10+ mentions
Atherosclerosis Risk in Communities (RRID:SCR_021769) ARIC disease-related portal, data or information resource, portal, topical portal Platform for prospective epidemiologic study conducted in four U.S. communities. One of most significant and longest running heart health studies and is the largest study of heart health in African Americans. ARIC investigates risk factors for heart disease and stroke, and connections between cardiovascular and cognitive health. ARIC includes two parts: Cohort Component and Community Surveillance Component. Cohort Component began in 1987, and each ARIC field center randomly selected and recruited cohort sample of individuals aged 45-64 from defined population in their community, to receive extensive examinations, including medical, social, and demographic data. In Community Surveillance Component, four communities are investigated to determine long term trends in hospitalized myocardial infarction and coronary heart disease deaths in men and women aged 35-84 years. Heart health studies, epidemiologic study, heart disease risk factors, stroke risk factors, cardiovascular and cognitive health connection, atherosclerosis risk coronary heart disease, stroke, myocardial infarction, atherosclerosis NHLBI PMID:2646917
PMID:34112321
Free, Freely available SCR_021769 The Atherosclerosis Risk in Communities (ARIC) Study 2026-02-14 02:04:21 35
Motif Mutation Analysis for Regulatory Genomic Elements
 
Resource Report
Resource Website
500+ mentions
Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) MMARGE data processing software, data analysis software, software toolkit, software application, software resource Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation. genome wide genetic variation, epigenetic data, identify collaborative transcription factor pairs, interpreting functional effects, non-coding genetic variation NCI CA173903;
NIGMS GM085764;
NIDDK DK091183;
NHLBI R00 123485
PMID:29893919 Free, Available for download, Freely available SCR_021902 2026-02-14 02:04:24 608

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