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http://sph.unc.edu/norc/administrative/

Core facility that is responsible for managing and organizing the activities of the internal governance committee and the external advisory board, promoting the techniques, methodologies, instrumentation, and resources offered by the core facilities, and supporting the integration of bioinformatics, biostatistics, clinical research, and metabolomics into clinical and translational research.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Administrative Core (RRID:SCR_015439) Copy   

•   Source: SciCrunch Registry

https://nyonrc.cumc.columbia.edu/content/human-phenotyping-core

Core which provides obesity and other medical eating disorder researchers with specialized measurements in body composition, energy expenditure, imaging analysis, and adipose tissue analysis in human subjects.

Proper citation: New York Obesity Nutrition Research Center Human Phenotyping Core (RRID:SCR_015437) Copy   

•   Source: SciCrunch Registry

http://norc.ucsf.edu/genetics-and-genomics-core-c

Core that provides services for genetic and genomic research, including DNA extraction, SNP genotyping, and gene expression, ES cell services with a high probability of germline transmission, microinjection of DNA for producing transgenic mice, microinjection of ES cells for producing gene knock-out mice, and 8 cell microinjection, and collection in vitro maturation and embryo transplant.

Proper citation: University of California San Francisco Nutrition and Obesity Research Center Genetics and Genomics Core (RRID:SCR_015447) Copy   

•   Source: SciCrunch Registry

http://www.norc.uab.edu/corefacilities/metabolism

Core whose services include energy expenditure, substrate metabolism and body composition analysis to provide assessments of human energy expenditure, substrate metabolism, body composition, body fat distribution, and bone quality.

Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Metabolism Core (RRID:SCR_015445) Copy   

•   Source: SciCrunch Registry

http://norc.ucsf.edu/human-metabolism-core

Core that renders services that provide consulting with study design, subject recruitment, and statistical analyses, conducting clinical research, and an array of specialized NORC-focused methods, instruments, and facilities for human body composition/metabolism, radiologic imaging and biobehavioral measurements for human nutrition, obesity and metabolism research.

Proper citation: University of California San Francisco Nutrition and Obesity Research Center Human Metabolism Core (RRID:SCR_015448) Copy   

•   Source: SciCrunch Registry

http://bnorc.org/cores/adipose.html

Core that facilitates and fosters research on mechanisms regulating white, brite or beige and brown adipose tissue mass, distribution, nutrient signaling and depot-specific metabolic and endocrine functions in health and disease.

Proper citation: Boston Nutrition and Obesity Research Centers Adipose Biology and Nutrient Metabolism Core (RRID:SCR_015419) Copy   

•   Source: SciCrunch Registry

http://bnorc.org/cores/epidemiology.html

Core that provides a central focus to translate the findings from clinical and cellular studies to applications in ongoing epidemiologic studies.

Proper citation: Boston Nutrition and Obesity Research Centers Epidemiology and Genetics Core (RRID:SCR_015421) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/administrative-core/

Core that supports and coordinates the NORCH and all the components of the center. It provides insight into the processes that govern the center, to recruit and vet new members, and to communicate with all our members about center happenings.

Proper citation: Nutrition and Obesity Research Centers at Harvard Administrative Core (RRID:SCR_015424) Copy   

•   Source: SciCrunch Registry

http://bnorc.org/cores/fgb.html

Core provides services to investigators within BNORC and the Boston area looking to expand their research using state-of-the-art genomic applications. This core utilizes technologies and sequencing platforms to help identify the complex molecular mechanisms underlying human disease.

Proper citation: Boston Nutrition and Obesity Research Centers Functional Genomics and Bioinformatics Core (RRID:SCR_015423) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/statistical-consultation/

Core that provides consultations for study design and analysis, preparation of grant applications, preparation of statistical methods and results for manuscripts on completed studies, responses to reviewer comments for manuscript resubmissions, identification of possible long term statistical collaborators for grants.

Proper citation: Nutrition and Obesity Research Centers at Harvard Statistical Consultation (RRID:SCR_015428) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/metabolic-phenotyping-core/

Core that provides NORCH investigators with access to model creation and detailed metabolic phenotyping. Its services include: model generation, including genomic targeting and production of metabolically relevant cell types; metabolic characterization of patient-derived, user-provided, or model generated samples; consultation on model development and metabolic characterization projects; and training for Core techniques in model generation and detailed metabolic characterization.

Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Phenotyping Core (RRID:SCR_015429) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/metabolic-imaging-core/

Core that links a variety of imaging facilities providing services to NORCH investigators who currently require or plan to conduct human studies using imaging research instrumentation and expertise. Its goal is to provide users with access to imaging technology for in-vivo phenotyping of human tissues for nutrition, obesity and metabolism studies.

Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Imaging Core (RRID:SCR_015426) Copy   

•   Source: SciCrunch Registry

https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core

Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.

Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/adipose-tissue-and-obesity-core/

Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research.

Proper citation: University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) Copy   

•   Source: SciCrunch Registry

https://nyonrc.cumc.columbia.edu/content/animal-phenotyping-core

Core that allows investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. Its services range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue.

Proper citation: New York Obesity Nutrition Research Center Animal Phenotyping Core (RRID:SCR_015414) Copy   

•   Source: SciCrunch Registry

http://www.medtronic.com/

Medical technology company that develops and manufactures devices and therapies to treat more than 30 chronic diseases, including heart failure, Parkinson's disease, urinary incontinence, Down syndrome, obesity, chronic pain, spinal disorders, and diabetes. A Commercial healthcare organization for both patients and healthcare professionals. For professionals, it provides products, therapy and procedure solutions, and services.

Proper citation: Medtronic (RRID:SCR_003988) Copy   

•   Source: SciCrunch Registry

http://psychology-tools.com/binge-eating-scale/

A 16 item questionnaire used to assess the presence of binge eating behavior indicative of an eating disorder that was devised specifically for use with obese individuals. The questions are based upon both behavioral characteristics (e.g., amount of food consumed) and the emotional, cognitive response, guilt or shame. Each question has 3-4 separate responses assigned a numerical value. The score range is from 0-46: * < 17 Non-Binging * 18-26 Moderate Binging * 27 and greater Severe Binging (Adapted from Wikipedia)

Proper citation: Binge Eating Scale (RRID:SCR_003694) Copy   

•   Source: SciCrunch Registry

http://www.geisinger.org/research/centers_departments/genomics/mycode/mycode.html

By collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.

Proper citation: Geisinger Biobank (RRID:SCR_005652) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/nia/

A cell repository containing cells and DNA for studies of aging and the degenerative processes associated with it. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer's disease, progeria, Parkinson's disease, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders, as well as DNA from individuals of advanced age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center and other Longevity Collections. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging, and both human and animal differentiated cell types. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research.

Proper citation: Aging Cell Repository (RRID:SCR_007320) Copy   

•   Source: SciCrunch Registry

http://coordinatingcenter.ucsf.edu/pride/

Randomized controlled trial being conducted at two clinical centers in the United States to learn more about the effects of weight loss on urinary incontinence. About 330 overweight women aged 30 or older will participate and will be followed for 18 months. Efficacy of weight reduction as a treatment for urinary incontinence will be examined at 6 months following the intensive weight control program, and the sustained impact of the intervention will be examined at 18 months. To increase the maintenance of weight reduction and facilitate evaluation of the enduring impact of weight loss on urinary incontinence, they propose to study a motivation-based weight maintenance program. At the end of the intensive weight control program, women randomized to the weight loss program will be randomized to either a 12-month skill-based maintenance intervention or to a motivation-based maintenance intervention. The maintenance interventions maximize the potential for sustained weight loss and will allow them to determine if long-term weight reduction will produce continued improvement in urinary incontinence.

Proper citation: Program to Reduce Incontinence by Diet and Exercise (RRID:SCR_009018) Copy   

•   Source: SciCrunch Registry