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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-02-14 02:00:11 6
MEME Suite - Motif-based sequence analysis tools
 
Resource Report
Resource Website
1000+ mentions
MEME Suite - Motif-based sequence analysis tools (RRID:SCR_001783) MEME Suite data processing software, data analysis service, analysis service resource, data or information resource, production service resource, data analysis software, service resource, source code, software application, software resource, database Suite of motif-based sequence analysis tools to discover motifs using MEME, DREME (DNA only) or GLAM2 on groups of related DNA or protein sequences; search sequence databases with motifs using MAST, FIMO, MCAST or GLAM2SCAN; compare a motif to all motifs in a database of motifs; associate motifs with Gene Ontology terms via their putative target genes, and analyze motif enrichment using SpaMo or CentriMo. Source code, binaries and a web server are freely available for noncommercial use. gene ontology, motif, comparative genomics, dna regulatory motif, dna sequence, dna, gene, transcription factor, genome, protein, analysis, function analysis, comparison, cluster, enrichment analysis, sequence analysis, bio.tools, FASEB list lists: DREME
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Glam2
is related to: ANNOgesic
is related to: memesuite-lite
has parent organization: National Biomedical Computation Resource
is parent organization of: GOMO - Gene Ontology for Motifs
NCRR R01 RR021692 PMID:19458158
DOI:10.1093/nar/gkl198
Free, Freely available nif-0000-10298, biotools:meme_suite, OMICS_08103 https://bio.tools/meme_suite http://meme.sdsc.edu/meme4_6_1/intro.html, http://meme.nbcr.net/meme/, https://sources.debian.org/src/meme/ SCR_001783 The MEME Suite 2026-02-14 02:00:18 2091
pFind Studio: pLink
 
Resource Report
Resource Website
10+ mentions
pFind Studio: pLink (RRID:SCR_000084) pLink software resource Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. mass spectrometry, proteomics, pFind Studio, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:22772728 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02404, biotools:pLink-2 https://github.com/pFindStudio/pLink3/releases http://pfind.ict.ac.cn/software/pLink/index.html SCR_000084 , pLink, pLink (pFind Studio), pLink2 2026-02-14 01:59:37 15
PsyGeNET
 
Resource Report
Resource Website
10+ mentions
PsyGeNET (RRID:SCR_014406) data processing software, data or information resource, data analysis software, software application, software resource, database Knowledge platform on psychiatric disorders and their genes. Resource for exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of database and set of analysis tools and is the result of the integration of information from DisGeNET and data extracted from the literature by text mining, followed by curation by domain experts. psychiatric disease, associated gene, database, analysis tool, bio.tools is used by: DisGeNET
is listed by: Debian
is listed by: bio.tools
Psychiatric disorder DOI:10.1093/bioinformatics/btv301 Available for the research community biotools:psygenet2r https://bio.tools/psygenet2r SCR_014406 Psychiatric disorders Gene association NETwork, Psychiatric disorders Gene association Network 2026-02-14 02:02:38 11
SCRATCH
 
Resource Report
Resource Website
100+ mentions
SCRATCH (RRID:SCR_014291) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Web protein structure and structural feature prediction server.Software suite includes predictors for secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts and tertiary structure. User provides amino acid sequence and selects desired predictions, then submits to the server. Protein predictor, secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts, tertiary structure prediction, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:15980571 Free, Freely available biotools:scratch https://bio.tools/scratch http://www.igb.uci.edu/servers/psss.html SCR_014291 Scratch Protein Predictor 2026-02-14 02:02:58 136
NNcon
 
Resource Report
Resource Website
1+ mentions
NNcon (RRID:SCR_014292) prediction, software tool Protein contact map prediction is useful for protein folding rate prediction, model selection and 3D structure prediction. Here we describe NNcon, a fast and reliable contact map prediction server and software. NNcon was ranked among the most accurate residue contact predictors in the Eighth Critical Assessment of Techniques for Protein Structure Prediction (CASP8), 2008. text mining objective, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:19420062 biotools:nncon https://bio.tools/nncon http://casp.rnet.missouri.edu/nncon.html SCR_014292 2026-02-14 02:02:37 2
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) data analysis software, software resource, data processing software, software application Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-14 02:02:57 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) sequence analysis software, data processing software, data analysis software, software application, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks
https://bio.tools/cufflinks
https://sources.debian.org/src/cufflinks/
SCR_014597 2026-02-14 02:02:57 8838
RAST Server
 
Resource Report
Resource Website
500+ mentions
RAST Server (RRID:SCR_014606) RAST production service resource, service resource A SEED-quality automated service that annotates complete or nearly complete bacterial and archaeal genomes across the entire phylogenetic tree. RAST can also be used to analyze draft genomes. microbiome, seed, annotate, genome, bacteria, archaea, service, bio.tools is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
National Science Foundation 0850546;
NIAID contract HHSN272200900040C
PMID:18261238 Free for the scientific community, Login required biotools:theseed https://bio.tools/theseed SCR_014606 Rapid Annotation using Subsystem Technology, Rapid Annotation using Subsystem Technology Server 2026-02-14 02:03:01 907
RepeatScout
 
Resource Report
Resource Website
500+ mentions
RepeatScout (RRID:SCR_014653) sequence analysis software, data processing software, data analysis software, software application, software resource, algorithm resource Algorithm used to identify de novo repeat families in newly sequenced genomes. Repeat libraries for C. briggsae, M. muscles (X chromosome), R. novegicus (X chromosome), armadillo, H. sapiens (X chromosome), and various other mammals created using RepeatScout are available on the main site., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. algorithm, sequence analysis, repeat, genome sequence, de novo, repeat family, repeat library, bio.tools is used by: RepeatModeler
is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:15961478 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:RepeatScout, biotools:RepeatScout https://bio.tools/RepeatScout
https://bio.tools/RepeatScout
https://bio.tools/RepeatScout
SCR_014653 2026-02-14 02:02:42 815
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) sequence analysis software, data processing software, data analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka
https://sources.debian.org/src/prokka/
https://sources.debian.org/src/prokka/
SCR_014732 2026-02-14 02:03:02 4876
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) sequence analysis software, data processing software, data analysis software, software application, software resource Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-02-14 02:02:59 1
DOGMA
 
Resource Report
Resource Website
100+ mentions
DOGMA (RRID:SCR_015060) software resource, web application Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. chloroplast, mitochondria, genome annotation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:15180927 Freely available biotools:DOGMA https://bio.tools/DOGMA SCR_015060 Dual Organellar GenoMe Annotator, Dual Organellar GenoMe Annotator (DOGMA) 2026-02-14 02:02:48 413
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE narrative resource, data or information resource, wiki Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-02-14 02:02:45 16
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) sequence analysis software, data visualization software, data processing software, data analysis software, software application, software resource Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview
https://sources.debian.org/src/seaview/
SCR_015059 2026-02-14 02:03:01 1777
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) sequence analysis software, data processing software, data analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX
https://bio.tools/MeroX
https://bio.tools/MeroX
SCR_014956 2026-02-14 02:02:45 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) data processing software, data analysis software, software application, software resource, algorithm resource Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Swiss National Science Foundation ;
Marie Curie International Outgoing Fellowship
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco
https://bio.tools/busco
https://sources.debian.org/src/busco/
SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-02-14 02:03:04 7284
fineSTRUCTURE
 
Resource Report
Resource Website
10+ mentions
fineSTRUCTURE (RRID:SCR_018170) data analysis software, software resource, data processing software, software application Software tool as algorithm for identifying population structure using dense sequencing data. Can perform model based Bayesian clustering on large datasets, including full resequencing data. Identifying population structure, dense sequencing data, Bayesian clustering, large dataset, data, analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:finestructure https://bio.tools/finestructure SCR_018170 FineSTRUCTURE version 2 2026-02-14 02:03:28 23
ChiCMaxima
 
Resource Report
Resource Website
1+ mentions
ChiCMaxima (RRID:SCR_018178) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling. Chromatin loop, CHi-C promoter, data, Hi-C visualization, interaction calling, data, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31118054 Free, Freely available biotools:ChiCMaxima https://bio.tools/ChiCMaxima SCR_018178 2026-02-14 02:03:17 2
SnpHub
 
Resource Report
Resource Website
1+ mentions
SnpHub (RRID:SCR_018177) software resource, web application Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data. Genomic, data, data visualization, data analysis, data retrieving, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31701415;
National Key Research and Development Program of China 2018YFD0100803;
National Key Research and Development Program of China 2016YFD0100801
Free, Available for download, Freely available biotools:SnpHub http://guoweilong.github.io/SnpHub/
https://bio.tools/SnpHub
SCR_018177 2026-02-14 02:03:34 1

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