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http://bioinfo.cipf.es/isacghtrac
Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations.
Proper citation: IsaCGH (RRID:SCR_008375) Copy
Public research university in New South Wales, Australia which offers degree programs across a wide spectrum of disciplines, as well as providing research facilities to scientists
Proper citation: University of Wollongong; New South Wales; Australia (RRID:SCR_008322) Copy
http://www.agingintervention.org/
A 501(c)(3) non-profit organization that gives out grants created to develop new therapies to control and reverse the causes of aging, as well as treat and prevent the diseases of aging. The goal is to eventually control the processes of aging, reverse their effects, and stay younger longer and ultimately create indefinite youthful, happy and productive lifespan using innovative scientific methods that are under development today in biotech companies and research labs around the world. The foundation also offers education on what we can do now to stay younger, live longer and be happier while new therapies are being developed.
Proper citation: Aging Intervention Foundation (RRID:SCR_008288) Copy
http://www.strout.net/conical/
CONICAL is a C++ class library for building simulations common in computational neuroscience. Currently its focus is on compartmental modeling, with capabilities similar to GENESIS and NEURON. Future classes may support reaction-diffusion kinetics and more. A key feature of CONICAL is its cross-platform compatibility; it has been fully co-developed and tested under Unix, DOS, and Mac OS. Any C++ compiler which adheres to the emerging ANSI standard should be able to compile the CONICAL classes without modification. It is intended to encourage the rapid development of simulator software, especially on non-Unix systems where such software is sorely lacking. The present focus of the CONICAL library of C++ classes is compartmental modeling. A model neuron is built out of compartments, usually with a cylindrical shape. When small enough, these open-ended cylinders can approximate nearly any geometry, just as the stack of cylinders approximates a cone in the logo above. While any compartment has passive electrical properties (like a simple resistor-capacitor circuit), more interesting properties require the use of active ion channels whose conductance varies as a function of the time or membrane voltage. A standard Hodgkin-Huxley ion channel is included as one of the built-in CONICAL object types. Most of the voltage-gated ion channels in the literature can be directly implemented merely by setting the parameters of this class. For extensibility, this class is derived from several layers of more general classes. Connections between neurons can be implemented in several ways. For a gap junction (i.e., simple electrical connection), a passive current (or pair of currents, one in each direction) can be used. Synapses are more complex objects, but used in a similar fashion. The Alpha-function synapse is a very popular model of synaptic transmission, and is a basic CONICAL class. More complex (and realistic) synapses can be built using the Markov-model synapse. (A Markov model can be used on its own for other purposes as well.) In addition to classes directly related to neural modeling, CONICAL contains several other useful object types. These include a current injector, and a column-oriented output stream for storing data in table form.
Proper citation: Conical: The Computational Neuroscience Class Library (RRID:SCR_008318) Copy
The mission of the Institute is to discover the key principles by which brains work and to implement these in artificial systems that interact intelligently with the real world. The Institute of Neuroinformatics is built of many people covering a wide range of disciplines and research areas. The major research projects and areas are listed below. - Behavior and Cognition: At the Institute of Neuroinformatics researchers investigate in Behavior and Cognition on various levels, ranging from neuronal circuit models of learning and adaptation over psychophysical experiments for color constancy up to modeling complex behavioral tasks such as exploration and goal-directed navigation. - Computation in Neural Circuits: By examining the brains of cats, rats and monkeys, and by making simulations of the cortex, INI hopes to learn how this circuit performs such widely different tasks. This knowledge might lead to advances in how computers are designed, and will certainly lead to advances in the subtlety and power of medical neuroscience. - Neurotechnologies: INI aims to harness the principles of biological computation, which can be expected to have a major impact on the technology market as autonomous intelligence pervades equipment, vehicles, buildings, utilities and clothing. Sponsors: INI is supported by European Union (EU), Gerbert Ruf Stiftung, Neuroscience Center (ZNZ), Swiss Confederation (KTI), Swiss Federal Institute of Technology Zurich (ETH), Swiss National Science Foundation (SNF), University of Zurich (UZH), and VW Stiftung
Proper citation: Institute of Neuroinformatics (RRID:SCR_008331) Copy
http://www.embl-heidelberg.de/Services/serrano/agadir/agadir-start.html
A prediction algorithm based on the helix/coil transition theory. Agadir predicts the helical behaviour of monomeric peptides. It only considers short range interactions. Conditions such as pH, temperature and ionic strength are used in the calculation. Modifications of the termini are also allowed. To submit a job to Agadir, log in the calculation part using the login button in the right bottom. Then fill-in the input form and proceed to next page, etc. You will reach a final page that resumes all the input information and allows you to run the calculation. You can submit one or more peptide sequences in one-letter format. Sequences should be separated by one return character. Spaces and tabulations are automatically removed. Only standard amino acids are accepted. Agadir accepts two modifications at the N-terminus (acetylation or succynilation), and one at the C-terminus (amidation). Just choose the desired option in the input form. You can use only one set of parameters: temperature, ionic strength (calibrated for NaCl) and pH, or explore a particular range of conditions for one parameter. In the latter case the intervals between any two values are: Ionic strength 0.05 M Temperature 1 K pH 0.2 units When setting the conditions for these parameters please be aware that the allowed ranges are: Ionic strength between 0.001 and 1 M Temperature between 273 and 400 K pH between 1 and 14 Output of the prediction at the residue level is available only when submitting no more than ten peptide sequences, and without any screening of conditions. Hstaple is the Hydrophobic Staple motif, Schellman is the Shellman motif, CaH are the expecte chemical shifts of the Calpha proton, 13Ca are the alpha Carbon 13 chemical shifts, JaN is the Jalpha--nitrogen coupling.
Proper citation: Agadir (RRID:SCR_008402) Copy
Sustainability plan EpiData Software has since 2000 grown from securing the principles of Epi Info V6 to an independent and documentation based system with several translations and numerous downloads. To secure continued viability organisations and governments work is being done to secure for the future, see also the license principles - the ambition is to convert the programs to open-source within few years. Contributions are used for costs of development after version 1.5 (e.g. refining of programming, enhancing speed, maintenance of website, to pay for absence from paid work to do EpiData or other developmental and promotional efforts for EpiData). About the EpiData Association EpiData Software is from EpiData Entry version 2.0 and above released by the non-profit organisation The EpiData Association Odense, Denmark (In Danish: EpiData foreningen). The association receives NO baseline budget from anyone. The association has no employees Postal adress is: The EpiData Association, att. Jens Lauritsen, Enghavevej 34, DK5230 Odense M, Denmark, Europe The body of users of EpiData form the most important part of the basis of the EpiData Association. Those who choose to register as users will be asked when desicions are to made regarding additions to the program. Needs for documentation etc. Registration is done by adding your e-mail to the Information list. Supporting members or institutions adds to the foundation and development of EpiData by securing funding to pay for the associated costs. List of donors. The board of the association is made up of the core persons developing EpiData, currently Jens M.Lauritsen and Michael Bruus in collaboration with experienced users and the Friends Of EpiData group (FoED), comprising a group of international persons wishing to support the development of EpiData Sponsor. Without support from a number of NGO''s, Universities, Regional Health Authorities and other funding bodies EpiData development would have stopped
Proper citation: EpiData Software (RRID:SCR_008485) Copy
http://www.theseed.org/DinsdaleSupplementalMaterial/
his table shows the metadata and links to sources of the data and citations associated with the publicly available metagenome sequences used in the Dinsdale, Edwards, et al., analysis of 87 different metagenomes. The links will take you to the annotated sequences in the metagenomics SEED, CAMERA, and the NCBI Short Read Archve. Please note that all metagenomes are currently available to download via the ftp links, some are available in the meta-RAST, and other links will be added as soon as they become available. Citations for individual metagenomes will also be added as and when they become available. DNA sequences for all metagenomes are avaialble via anonymous FTP. Sponsor. This project was supported by the Gordon and Betty Moore Foundation Marine Microbial Initiative, National Science Foundation grants (F.R. and D.L.V.), a Department of Commerce ATP grant (F.R.), a National Research Initiative Competitive Grant from the USDA Cooperative State Research, Education and Extension Service (B.W.), the National Institute of Allergy and Infectious Diseases, the National Institutes of Health and the Department of Health and Human Services (R.S.).
Proper citation: Metagenomes Used in The Statistical Analysis (RRID:SCR_008483) Copy
http://www.flintbox.com/technology.asp?page=3716
Welcome to Flintbox, an application that revolutionizes the way the innovation community can share technologies, distribute new materials and software, and collaborate on research projects. Hundreds of research institutions are participating in the Flintbox open innovation network. Become a member to contribute and explore We are excited to present the Flintbox Application Programming Interface (API) to provide users with an easy way to upload data from any system to Flintbox. This freely available tool for synchronized information exchange will be a valuable resource to the open innovation community. The Flintbox API gives you the power to: Import existing technology postings directly into Flintbox Avoid duplicate data entry to market your technologies, ideas, and materials Create postings from any database Export project information to other websites For more information about using and implementing the Flintbox API, please see the About the Flintbox API page. Featured Project The New Flintbox offers expanded transactional capabilities: credit cards, purchase orders, purchase authorizations, donations, and much more The global Flintbox community is ideal for marketing new technologies, creative works, course materials, and innovative ideas. Flintbox enables universities to maximize their outreach to a broad spectrum of the innovation community. Plus, Wellspring provides expertise in assisting TTOs, inventors, and industrial liaison offices to promote their technologies, research programs, and partnering opportunities to Flintbox. Flintbox for Corporations Corporations turn to Flintbox to cultivate existing relationships and engage in new opportunities for collaborative research and solution sourcing from universities and other companies. For example, a pharmaceutical firm uses Flintbox to provide researchers and physicians software to assess patient outcomes. Flintbox for Technology Communities Flintbox empowers technology communities to connect effectively in a geographic region, building a Sphere of Innovation to truly recognize and capitalize on the valuable relationships and innovation assets in your community. For example, by creating or joining a community Group of members with common interests, say tissue engineering or artificial intelligence, you can link to other groups and explore common interests and complementary resources, for a dynamic collaborative effort and to efficiently share related technology projects. Flintbox is a registered trademark of Wellspring Worldwide, LLC
Proper citation: Flintbox (RRID:SCR_008519) Copy
This document defines the processes and standards that all FLTK developers must follow when developing and documenting FLTK, and how trouble reports are handled and releases are generated. The purpose of defining formal processes and standards is to organize and focus our development efforts, ensure that all developers communicate and develop software with a common vocabulary/style, and make it possible for us to generate and release a high-quality GUI toolkit which can be used with a high degree of confidence. Much of this file describes the existing practices that have been used up through FLTK 1.1.x, however I have also added some new processes/standards to use for future code and releases. The fltk-dev mailing list and fltk.development newsgroup are the primary means of communication between developers. All major design changes must be discussed prior to implementation. Specific Goals The specific goals of the FLTK are as follows: Develop a C++ GUI toolkit based upon sound object-oriented design principles and experience. (*) Minimize CPU usage (fast). (*) Minimize memory usage (light). (*) Support multiple operating systems and windowing environments, including UNIX/Linux, MacOS X, Microsoft Windows, and X11, using the native graphics interfaces. (*) Support OpenGL rendering in environments that provide it. (*) Provide a graphical development environment for designing GUI interfaces, classes, and simple programs. (*) Support UTF-8 text. Support printer rendering in environments that provide it. Support schemes, styles, themes, skinning, etc. to alter the appearance of widgets in the toolkit easily and efficiently. The purpose is to allow applications to tailor their appearance to the underlying OS or based upon personal/user preferences. Support newer C++ language features, such as templating via the Standard Template Library (STL), and certain Standard C++ library interfaces, such as streams. However, FLTK will not depend upon such features and interfaces to minimize portability issues. Support intelligent layout of widgets. Many of these goals are satisfied by FLTK 1.1.x (*), and many complex applications have been written using FLTK on a wide range of platforms and devices. Development of the remaining features is proceding for FLTK 2.0 with a new, namespace-based API. While 2.0 offers some limited 1.x source compatibility, the changes to the underlying widget classes are significant enough to prevent full compatibility. Software Development Practices Documentation All widgets are documented using the Doxygen software; Doxygen comments are placed in the header file for the class comments and any inline methods, while non-inline methods should have their comments placed in the corresponding source file. The purpose of this separation is to place the comments near the implementation to reduce the possibility of the documentation getting out of sync with the code. All widgets must have a corresponding test program which exercises all widget functionality and can be used to generate image(s) for the documentation. Complex widgets must have a written tutorial, either as full text or an outline for later publication The final manuals are formatted using the HTMLDOC software. Sponsor. Easy Software Products
Proper citation: Fast Light Toolkit (RRID:SCR_008514) Copy
http://fluxus-technology.com/sharenet.htm
DNA software and consultancy: The DNA Alignment software and Network software is used by biologists, anthropologists, medical researchers and students world wide. We carry out phylogeographic consultancy for US, UK and German clients, including legal medical work. We were involved in the tv projects The Real Eve (Discovery Channel) and Motherland (BBC). Our biotechnological director Dr Peter Forster is on the editorial board of the International Journal of Legal Medicine since 1999. Technology and sales consultancy: Clients include multinational corporations, research institutions, and medium to small businesses. Client quotes: Vorbildlicher Einsatz (Dr Stephan Hitzel, EADS, in CADplus 1/2003 journal, Cover Story). We have had an effective business relationship with Fluxus Technology since 1999, and their experience of the German market has proved to be invaluable as part of our operations supplying high end engineering software and consultancy services right across the engineering supply chain (Andy Chinn, Business Development Manager, ITI TranscenData, February 2006). Abstract. Indo-European is the largest and best-documented language family in the world, yet the reconstruction of the Indo-European tree, first proposed in 1863, has remained controversial. Complications may include ascertainment bias when choosing the linguistic data, and disregard for the wave model of 1872 when attempting to reconstruct the tree. Essentially analogous problems were solved in evolutionary genetics by DNA sequencing and phylogenetic network methods, respectively. We now adapt these tools to linguistics, and analyze Indo-European language data, focusing on Celtic and in particular on the ancient Celtic language of Gaul (modern France), by using bilingual GaulishLatin inscriptions. Our phylogenetic network reveals an early split of Celtic within Indo-European. Interestingly, the next branching event separates Gaulish (Continental Celtic) from the British (Insular Celtic) languages, with Insular Celtic subsequently splitting into Brythonic (Welsh, Breton) and Goidelic (Irish and Scottish Gaelic). Taken together, the network thus suggests that the Celtic language arrived in the British Isles as a single wave (and then differentiated locally), rather than in the traditional two-wave scenario (P-Celtic to Britain and Q-Celtic to Ireland). The phylogenetic network furthermore permits the estimation of time in analogy to genetics, and we obtain tentative dates for Indo-European at 8100 BC 1,900 years, and for the arrival of Celtic in Britain at 3200 BC 1,500 years. The phylogenetic method is easily executed by hand and promises to be an informative approach for many problems in historical linguistics.
Proper citation: Fluxus (RRID:SCR_008517) Copy
http://www.daylight.com/dayhtml/doc/theory/
Daylight provides enterprise-level cheminformatics software technologies to life science companies. Our superior chemistry, high performance, and open architecture have earned Daylight a reputation for delivering the state-of-the-art in chemical information processing since 1987. Daylight Chemical Information Systems, Inc. is a privately held company with corporate offices in Aliso Viejo, CA and research offices in Santa Fe, NM and Cambridge, England. Support At Daylight, support means a wide array of services that are designed to empower users to make the most of Daylight software. We offer detailed administration documentation and guides through this website. Our User Group Meetings allow in-depth exploration of our technology. And, of course, our support staff is available to assist you whenever the need occurs. Download - Downloading current releases as well as contributed code, system requirements, installation directions, and release information Reference Guides - List of available documentation such as programming guides and user manuals. Cheminformatics - List of additional general resources including introductory materials, theory manual, tutorials and user meeting archives. Sponsor. Daylight
Proper citation: Daylight (RRID:SCR_008474) Copy
http://helixweb.nih.gov/dnaworks
DNAWorks automates the design of oligonucleotides for gene synthesis by PCR-based methods. The availability of sequences of entire genomes has dramatically increased the number of protein targets, many of which will need to be overexpressed in cells other than the original source of DNA. Gene synthesis often provides a fast and economically efficient approach. The synthetic gene can be optimized for expression and constructed for easy mutational manipulation without regard to the parent genome. DNAWorks accesses a computer program that automates the design of oligonucleotides for gene synthesis. The website provides forms for simple input information, i.e. amino acid sequence of the target protein and melting temperature (needed for the gene assembly) of synthetic oligonucleotides. The program outputs a series of oligonucleotide sequences with codons optimized for expression in an organism of choice. Those oligonucleotides are characterized by highly homogeneous melting temperatures and a minimized tendency for hairpin formation. The approach presented here simplifies the production of proteins from a wide variety of organisms for genomics-based studies.
Proper citation: DNAWorks at Helix Systems (RRID:SCR_008470) Copy
http://seqpig.sourceforge.net/
A software library for Apache Pig for the distributed analysis of large sequencing datasets on Hadoop clusters.
Proper citation: SeqPig (RRID:SCR_008548) Copy
http://rmaexpress.bmbolstad.com
RMAExpress is a standalone GUI program for Windows (and Linux) to compute gene expression summary values for Affymetrix Genechip data using the Robust Multichip Average expression summary and to carry out quality assessment using probe-level metrics. It does not require R nor is it dependent on any component of the BioConductor project. If focuses on processing 3'' IVT expression arrays, exon and WT gene arrays. What is RMA? RMA is the Robust Multichip Average. It consists of three steps: a background adjustment, quantile normalization (see the Bolstad et al reference) and finally summarization. Some references (currently published) for the RMA methodology are: Bolstad, B.M., Irizarry R. A., Astrand, M., and Speed, T.P. (2003), A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Bias and Variance. Bioinformatics 19(2):185-193 Supplemental information Rafael. A. Irizarry, Benjamin M. Bolstad, Francois Collin, Leslie M. Cope, Bridget Hobbs and Terence P. Speed (2003), Summaries of Affymetrix GeneChip probe level data Nucleic Acids Research 31(4):e15 Irizarry, RA, Hobbs, B, Collin, F, Beazer-Barclay, YD, Antonellis, KJ, Scherf, U, Speed, TP (2002) Exploration, Normalization, and Summaries of High Density Oligonucleotide Array Probe Level Data. Accepted for publication in Biostatistics. [Abstract, PDF, PS, Complementary Color Figures-PDF, Software] What do I need? You will need the appropriate CDF and CEL files for your dataset. For Exon and WT Gene arrays, the PGF and CLF should be used instead of the CDF file to build a CDFRME file. The process for doing this is explained in the user manual. Some pre-built CDFRME files are also available. CDFRME files HuEx_CDFRME.zip (95.9MB) HuGene_CDFRME.zip (5.5MB) MoEx_CDFRME.zip (79.6MB) MoGene_CDFRME.zip (6.3MB) RaEx_CDFRME.zip (48.4MB) RaGene_CDFRME.zip (5.7MB) Can I use affy/BioConductor instead? Of course. Hypothetically you will get the same results from both places, provided you have consistent settings in affy/BioConductor and RMAExpress. Some people prefer the power and flexibility of R and others like the point and click simplicity of a GUI. RMAExpress caters to the second option. Since RMAExpress outputs the computed expression values to a text file, you may of course load the expression measures into R and use features of Bioconductor for the analysis of your gene expression values. You can of course open the results file in any other application that supports importing plain text files. Will I get the same results as I would using affy/Bioconductor? Yes. The results from RMAExpress should be consistent. What are the machine requirements? A good rule of thumb is the more RAM you have the better. I would recommend at least 1GB, though 512MB will work in most situations. At this point the program has been tested using Windows 2000, Windows XP, Windows Vista and Linux. Most recently I have had a report of over 10,000 arrays processed in a single session. Can I do any quality assessment? Yes, store the residuals when you compute the expression values. Then you may examine chip pseudo-images of the residuals. Note that high positive residuals are colored increasingly read and low negative residuals are colored increasingly blue. To better interpret these images and gain a better feel for what is typical you may visit the PLM Image Gallery where images for a number of different datasets are shown. Access to the NUSE and RLE quality assessment metrics is also provided. How do I download and install it? Click here for the current release Windows version. Use the installer to install the program. The current release version number is 1.0 (released June 29, 2008). A pre-built linux version is not currently available, but you may build it using the source code. You can download pre-release versions from the following table (the release versions will be more stable, the development versions may have features that are incomplete or will be removed or altered before the next release was supported by the PGA U01 HL66583.
Proper citation: RMA Express (RRID:SCR_008549) Copy
http://statgen.ncsu.edu/qtlcart/
QTL Cartographer is a suite of programs to map quantitative traits using a map of molecular markers. The programs are available via an anonymous ftp server. See the README for more information. You will also want a copy of Gnuplot to display plots made by QTL Cartographer. Gnuplot is freely available on the web. Do a search to find the latest version for your operating system. Windows QTL Cartographer Windows QTL Cartographer is a user friendly version of QTL Cartographer. It has a GUI interface and runs under Microsoft Windows. Manual The manual for QTL Cartographer is written in LaTeX2e. An Adobe Portable document format (pdf) version is available with the distribution of the programs. Look in the doc/pdf folder for the manual.pdf file. This file can be printed or viewed using Acrobat Reader, available through the Adobe website. The manual has also been translated into html. It is available through the following link. Please note that the translator is not perfect: The pdf form of the manual is much more accurate. Specifically, latex2html failed to translate figure 2.4 and simply printed 2.3 twice. Man Pages In the UNIX world, it is comman to have man pages for programs. We have written such a set of man pages, and these are available with the UNIX distribution. The man pages are also a part of the manual.pdf file. Here is a list of the man pages. 1. Emap 2. Rmap 3. Rqtl 4. Rcross 5. Qstats 6. LRmapqtl 7. SRmapqtl 8. Zmapqtl 9. JZmapqtl 10. MImapqtl 11. MultiRegress 12. Prune 13. Preplot 14. Eqtl 15. QTLcart Perl scripts QTL Cartographer comes with some perl scripts to automate repetitive tasks and reformat output files. They are available in the doc/scripts subdirectory of the distribution. Here are the man pages that explain what the scripts can do. 1. Bootstrap.pl is a script for running a bootstrap analysis. 2. CWTupdate.pl is used with Permute.pl for the comparison-wise thresholds. 3. EWThreshold.pl is used with Permute.pl for the experiment-wise thresholds. 4. GetMaxLR.pl is used with Permute.pl for the experiment-wise thresholds. 5. Model8.pl iterates Zmapqtl to find a stable set of cofactors for composite interval mapping. 6. Permute.pl is a script for running a permutation test. 7. Prepraw.pl allows you to reformat and check a Mapmaker data file. 8. SRcompare.pl will compare the set of cofactors in two SRmapqtl output files. 9. SSupdate.pl is used with Bootstrap.pl to update the sum and sum of squares for the likelihoods and parameter estimates. 10. Vert.pl converts text file line endings between Unix, Macintosh and Windows. 11. Ztrim.pl redisplays Zmapqtl output so that it fits in a terminal window. Data We are now posting published data sets to our web site. A list of links to the ftp subdirectories follows. Each directory contains a set of text files of data. Please read the Readme file in the directory for information on the data. 1. Zeng et al provide data for their paper Genetic architecture of a morphological shape difference between two Drosophila species. If you have any data that you would like to make available via our server, contact Chris Basten. Presentations From time to time, Chris Basten gives presentations on how to use QTL Cartographer. These presentations are created in Microsoft Powerpoint. The source file for the presentation is available with the distribution of the programs. Look in the doc subdirectory. Binary Traits See this for more information on the BTmapqtl module. This is an add-on written in LaurenMcIntyre''s lab. BTmapqtl is in the binary directory of the distribution (and is created with a make for the UNIX version).
Proper citation: Bionformatics Research Center (RRID:SCR_008540) Copy
http://mothra.ornl.gov/cgi-bin/cat/cat.cgi
A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CAT (RRID:SCR_008421) Copy
A commercial organization which provides assay technologies to isolate DNA, RNA, and proteins from any biological sample. Assay technologies are then used to make specific target biomolecules, such as the DNA of a specific virus, visible for subsequent analysis.
Proper citation: QIAGEN (RRID:SCR_008539) Copy
Features: * This software takes a list of p-values resulting from the simultaneous testing of many hypotheses and estimates their q-values. A point-and-click interface is now available! * The q-value of a test measures the proportion of false positives incurred (called the false discovery rate) when that particular test is called significant. * A short tutorial on q-values and false discovery rates is provided with the manual. * Various plots are automatically generated, allowing one to make sensible significance cut-offs. * Several mathematical results have recently been shown on the conservative accuracy of the estimated q-values from this software. * The software can be applied to problems in genomics, brain imaging, astrophysics, and data mining. This research was supported in part by a National Science Foundation graduate research fellowship.
Proper citation: Q-Value Software (RRID:SCR_008538) Copy
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