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Provides microscopes and imaging stations. Expert staff offers guide to non-expert users. Facility offers imaging expertise in Electron Microscopy, Optical Microscopy, In Vivo Imaging, and Histology.
Proper citation: University of Notre Dame Integrated Imaging Core Facility (RRID:SCR_022743) Copy
http://www.ohsu.edu/xd/research/research-cores/small-animal-research-imaging-core/
Provides in vivo imaging technology to evaluate anatomy, tissue function, cellular and molecular phenotype, blood/fluid flow, metabolism and to assess pharmacokinetics and stem cell function in small animal models.Offers spatial resolution, temporal resolution, tissue differentiation, sensitivity for contrast agent, and performance of contrast agents. Services include MicroPET/SPECT/CT imaging,Ultra-high frequency small animal ultrasound imaging,Biophotonics imaging.
Proper citation: Oregon Health and Science University Small Animal Research Imaging Core Facility (RRID:SCR_022742) Copy
https://ncdiabetesresearch.org/acsmc
Core to leverage data, patient populations and investigators at each NCDRC institution, including accessing expertise and resources of regional Clinical and Translational Science Institute hubs (Duke, UNC, and Wake Forest). Research navigators in ACSMC provides input and navigation of clinical research resources available to diabetes investigators based on extensive experience in diabetes specific studies and methodology and deep knowledge of NCDRC resources available at each institution.
Proper citation: North Carolina Diabetes Research Center Advanced Clinical Study Methods Core Facility (RRID:SCR_022908) Copy
Provides diabetes researchers at University of Colorado with access to microscopy and mass cytometry systems. Provides expertise and training to use equipment effectively for diabetes related tissues; expertise and validated diabetes related resources to prepare samples appropriately; guidance to design experiments; resources to analyze data; assistance with data interpretation.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Cell and Tissue Analysis Core Facility (RRID:SCR_022906) Copy
Provides diabetes researchers with access to novel human stem cell-derived in vitro cell models for investigating cellular and molecular features of both Type 1 and Type 2 diabetes. Recent progress in stem cell, organoid culture, gene editing and directed differentiation technologies has afforded opportunities to develop pre-clinical human models.Provides expertise, infrastructure and access to novel human model systems and technologies to DRC investigators. Provides expertise, resources and training in stem cell technologies together with quality control testing, validation standardization and authentication all model platforms and reagents.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Disease Modeling Core Facility (RRID:SCR_022905) Copy
Core leverages current clinical research facilities and equipment available at Barbara Davis Center for Childhood Diabetes, UC AMC Clinical Translational Research Center, University of Colorado Hospital, Denver Veteran Administration Medical Center and Children Hospital Colorado.Core integrates diabetes research across these institutions through communication and distribution of resources available, and creates shared sample and data biobanks and recruiting database of mothers, infants, children, adolescents and adults with diabetes, diabetes risk and controls.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Clinical Resource Core Facility (RRID:SCR_022903) Copy
Research facility for studying paramagnetic centers by continuous wave and pulsed EPR techniques to obtain information on electronic, chemical, and geometric molecular structures.
Proper citation: University of Arizona Electron Paramagnetic Resonance Core Facility (RRID:SCR_022883) Copy
Provides services including Next Generation Sequencing, single cell Genomics, and Spatial Transcriptomics facility. Provides experimental design support, library generation, and Illumina and Nanopore Sequencing.
Proper citation: Van Andel Institute Genomics Core Facility (RRID:SCR_022913) Copy
Pathology and Biorepository Core (PBC) integrates anatomic pathology expertise with biorepository and biospecimen science. It provides emphasis on high-quality biospecimens and interpretable results to validate experimental models and extend them to clinical samples. The PBC offers a comprehensive range of biospecimen services, including histology, pathology, and biospecimen processing and storage.
Proper citation: Van Andel Institute Pathology and Biorepository Core Facility (RRID:SCR_022912) Copy
Research on microbial agents, which cause lethal diseases in humans and for which effective drugs or preventive vaccines are not available, must be conducted by well-trained investigators in specially built, well-maintained laboratories. Core provides the triad of service, research and development, and education and training.
Proper citation: University of Hawaii at Manoa ABSL3/BSL3 Biocontaminant Core Facility (RRID:SCR_022878) Copy
Offers services to researchers looking for collaborators or contractors for their educational or training projects.Offers development tools and hosting services to educators creating their own online training resources.
Proper citation: Texas A and M University Center for Educational Technologies Core Facility (RRID:SCR_022691) Copy
https://www.chumontreal.qc.ca/crchum/plateformes-services/imagerie-cellulaire
Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.
Proper citation: University of Montreal CRCHUM Cell Imaging Core Facility (RRID:SCR_022726) Copy
Offers services in fragment based screening and drug discovery, characterization and QC of biologics and biosimilar drugs, metabolomics, protein NMR, small molecule NMR, and NMR of natural products. Offers 400-700MHz systems, many with cryogenic probes.
Proper citation: Harvard Medical School Biomolecular Nuclear Magnetic Resonance Core Facility (RRID:SCR_022967) Copy
https://drexel.edu/core-facilities/facilities/cell-imaging/
Facility housed in purpose built imaging suites in Papadakis Integrated Sciences Building and in Bossone Research Center. Serves light microscopy needs of Drexel researchers and supports teaching missions of Biology and Biomedical Engineering curricula and provides service to users from local biotech companies.Provides facility, expertise, and education in advanced quantitative light microscopy.
Proper citation: Drexel University Cell Imaging Center Core Facility (RRID:SCR_022689) Copy
https://research.utexas.edu/cbrs/cores/cbb/
Provides support for students, postdoctoral fellows, and faculty interested in the use of computational approaches to solving biological problems. Our goal is to lower as much as possible the threshold to enter the -omics area of the life sciences.
Proper citation: University of Texas at Austin Computational Biology and Bioinformatics Core Facility (RRID:SCR_022688) Copy
https://www.umassmed.edu/scope/
Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.
Proper citation: University of Massachusetts Medical School Sanderson Center for Optical Experimentation Core Facility (RRID:SCR_022721) Copy
https://ag.purdue.edu/department/arge/facilities-and-research/microscopy/index.html
Provides Purdue researchers access to electron microscopy instrumentation including scanning electron microscopes, small dual beams and transmission electron microscopes. Expert staff scientists help with training and project support.
Proper citation: Purdue Electron Microscopy Center (RRID:SCR_022687) Copy
https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php
Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.
Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy
https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/
Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.
Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy
https://www.med.unc.edu/humancellcore/
Provides services to conduct basic as well as translational research using human induced pluripotent cells. Offers Reprogramming, Genome editing and directed cell differentiation.
Proper citation: University of North Carolina at Chapel Hill Human Pluripotent Cell Core Facility (RRID:SCR_023246) Copy
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