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http://www.norch.org/administrative-core/

Core that supports and coordinates the NORCH and all the components of the center. It provides insight into the processes that govern the center, to recruit and vet new members, and to communicate with all our members about center happenings.

Proper citation: Nutrition and Obesity Research Centers at Harvard Administrative Core (RRID:SCR_015424) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/marsicolunginstitute/core-facilities/mousemodelscore

Core that provides support and expertise for mouse colony maintenance, breeding strategies, mouse lung phenotyping protocols, and submission of live-animal applications to maintain compliance with IACUC guidelines.

Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core (RRID:SCR_015389) Copy   

•   Source: SciCrunch Registry

http://bnorc.org/cores/fgb.html

Core provides services to investigators within BNORC and the Boston area looking to expand their research using state-of-the-art genomic applications. This core utilizes technologies and sequencing platforms to help identify the complex molecular mechanisms underlying human disease.

Proper citation: Boston Nutrition and Obesity Research Centers Functional Genomics and Bioinformatics Core (RRID:SCR_015423) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10822/community_id/1418

Core that ensures the health and welfare of mouse models by assuring that mice admitted to the MMPC meet defined health criteria and that post-quarantine protocol assignment. It diagnoses disease and identifies unique metabolic or cardiovascular phenotypes of mice through interaction with the Comparative Pathology Subcore.

Proper citation: MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core (RRID:SCR_015380) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/statistical-consultation/

Core that provides consultations for study design and analysis, preparation of grant applications, preparation of statistical methods and results for manuscripts on completed studies, responses to reviewer comments for manuscript resubmissions, identification of possible long term statistical collaborators for grants.

Proper citation: Nutrition and Obesity Research Centers at Harvard Statistical Consultation (RRID:SCR_015428) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/metabolic-phenotyping-core/

Core that provides NORCH investigators with access to model creation and detailed metabolic phenotyping. Its services include: model generation, including genomic targeting and production of metabolically relevant cell types; metabolic characterization of patient-derived, user-provided, or model generated samples; consultation on model development and metabolic characterization projects; and training for Core techniques in model generation and detailed metabolic characterization.

Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Phenotyping Core (RRID:SCR_015429) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/metabolic-imaging-core/

Core that links a variety of imaging facilities providing services to NORCH investigators who currently require or plan to conduct human studies using imaging research instrumentation and expertise. Its goal is to provide users with access to imaging technology for in-vivo phenotyping of human tissues for nutrition, obesity and metabolism studies.

Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Imaging Core (RRID:SCR_015426) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/translational-core

Core that provides human primary nasal airway epithelial cells and bronchial airway epithelial cells, expertise in the nasal potential difference measurement, and a means to understand pathogenesis of cystic fibrosis and other metabolic diseases.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Clinical and Translational Core (RRID:SCR_015399) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/animal-core

Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core (RRID:SCR_015396) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/cftr-expression-core

Core that maintains a repository of reagents for studying CFTR and assists with expression technologies using vaccinia, adenovirus and other methodologies and antibody based detection of cystic fibrosis related gene products.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Transmembrane Conductance Regulator Expression Core (RRID:SCR_015397) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=30

Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure.

Proper citation: MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc/cores/metabolism/

Core that conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic beta-cell function, body composition and energy balance. Its services include access to hyperglycemic clamps to assess insulin secretion and pancreatic beta cell function in awake mice and exercise studiesl with acute, chronic endurance, and exhaustive exercise protocols and using in-house cage wheels.

Proper citation: MMPC-University of Massachusetts Medical School Metabolism Core (RRID:SCR_015369) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/cfrtc/microbiology/

Core facility which provides tools, reagents, and training for microbiological researchers investigating cystic fibrosis. They specifically provide resources for research in anti-bacterial therapies,

Proper citation: Cystic Fibrosis Center - University of Washington Microbiology Core (RRID:SCR_015403) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=37

Core that offers measurement of gut permeability, plasma lipopolysaccharide binding protein (LBP) assay, and inflammatory profiling.

Proper citation: MMPC-University of California Davis Microbiome and Host Response Core (RRID:SCR_015361) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/adipose-tissue-and-obesity-core/

Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research.

Proper citation: University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/cfrtc/genomics/

Core provides genomics-based tools, data management and analysis tools, and creates platforms that integrate data from the Clinical and Immunology Cores for human samples and bacterial isolates. Services include consultation and experimental design assistance for using new-generation sequencing technology, data analysis, bioinformatic support, data access and storage, high throughput and new-generation whole-genome sequencing, and RNA-seq analysis of transcriptomes.

Proper citation: University of Washington Genomics Core Cystic Fibrosis Research Translation Center and Research Development Program (RRID:SCR_015404) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/gtp/immunology.shtml

Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies.

Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=48

Core which provides a complete range of microvascular phenotyping of murine models of diabetes, obesity and metabolic disease, including validated, reproducible and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy and retinopathy.

Proper citation: MMPC-University of Michigan Medical School Microvascular Complications Core (RRID:SCR_015376) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10810/community_id/1418

Core whose services include determining the components of energy balance with high precision and time resolution, providing robust imaging technology to monitor the dynamics of cellular process, and providing innovative mouse bariatric surgery models with application to basic and translational research.

Proper citation: MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core (RRID:SCR_015377) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/cells-and-tissue-core

Core that provides centralized access to non-cystic fibrosis and cystic fibrosis tissue specimens and airway cells used for model systems to assess gene transfer to the airway and pathophysiology in cystic fibrosis.

Proper citation: University of Iowa Center for Gene Therapy Cell Tissue Core (RRID:SCR_015410) Copy   

•   Source: SciCrunch Registry