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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Extending Guilt by Association by Degree
 
Resource Report
Resource Website
1+ mentions
Extending Guilt by Association by Degree (RRID:SCR_018427) EGAD data processing software, data analysis software, software toolkit, software application, software resource Software package implements series of highly efficient tools to calculate functional properties of networks based on guilt by association methods. Ultra fast functional analysis of gene networks. Extending guilt, association by degree, functional properties calculation, guilt network, association method, functional analysis, gene network is listed by: Bioconductor Free, Available for download, Freely available SCR_018427 EGAD Bioconductor, Extending guilt by association by degree 2026-02-13 10:58:21 6
EnhancedVolcano
 
Resource Report
Resource Website
100+ mentions
EnhancedVolcano (RRID:SCR_018931) data visualization software, software resource, data processing software, software application Software R package to produce publication ready volcano plots with enhanced colouring and labeling. Used to visualise results of differential expression analyses. Publication ready plot, enhanced coloring, enhanced labeling, data visualisation, differential expression analyses, plot, volcano plot uses: ggplot2
uses: ggrepel
is listed by: Bioconductor
Free, Available for download, Freely available https://github.com/kevinblighe/EnhancedVolcano SCR_018931 2026-02-13 10:58:17 469
DEGreport
 
Resource Report
Resource Website
10+ mentions
DEGreport (RRID:SCR_018941) data analysis software, software resource, data processing software, software application Software R package for creation of HTML report of differential expression analyses of count data. Integrates some of code mentioned in DESeq2 and edgeR vignettes, and reports ranked list of genes according to fold changes mean and variability for each selected gene. HTML report creation, differential expression analyses, count data, code integration, gene list report is listed by: Bioconductor Free, Available for download, Freely available http://lpantano.github.io/DEGreport SCR_018941 2026-02-13 10:58:19 16
GEO2R
 
Resource Report
Resource Website
50+ mentions
GEO2R (RRID:SCR_016569) data analysis software, software resource, data processing software, software application Software as an interactive web tool to compare two or more groups of samples in a Gene Expression Omnibus (GEO) series regardless of data type and quality. Used to identify genes that are differentially expressed across experimental conditions. Results are presented as a table of genes ordered by significance. compare, group, sample, gene, expression, omnibus, data, identify, differentially, expressed, across, condition, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
is related to: GEOquery
is related to: LIMMA
Free, Available for download, Freely available biotools:GEO2R https://bio.tools/GEO2R SCR_016569 2026-02-13 10:57:50 58
VisR
 
Resource Report
Resource Website
1+ mentions
VisR (RRID:SCR_016658) VisR data visualization software, data processing software, data analysis software, software toolkit, software application, software resource Software as an R-based visual framework for analysis of sequencing datasets. Provides a framework for integrative and interactive analyses. visual, framework, analysis, sequencing, data, dataset, integrative, interactive, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Bioconductor
Michael Smith Foundation for Health Research ;
Canadian Institutes of Health Research (CIHR) and Genome BC ;
NSERC PGS-D
PMID:26328469 Free, Available for download, Freely available biotools:VisR https://bio.tools/VisR SCR_016658 VisRseq, VisR 2026-02-13 10:57:51 5
FlowSOM
 
Resource Report
Resource Website
100+ mentions
FlowSOM (RRID:SCR_016899) data visualization software, data processing software, data analysis software, software application, software resource Software tool to analyze Flow or mass cytometry data using a Self-Organizing Map. Used to obtain an overview of how all markers are behaving on all cells, and to detect subsets that might be missed otherwise. flow, cytometry, data, analysis, self, organizing, map, marker, cell, detect, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: R Project for Statistical Computing
is a plug in for: FlowJo
PMID:25573116 Free, Available for download, Freely available biotools:flowsom https://bioconductor.org/packages/release/bioc/html/FlowSOM.html
https://www.flowjo.com/exchange/#/plugin/profile?id=7
https://bio.tools/flowsom
SCR_016899 FlowSOM, Flow Self Organizing Map 2026-02-13 10:57:48 106
ropls
 
Resource Report
Resource Website
10+ mentions
ropls (RRID:SCR_016888) R OPLS data analysis software, software resource, data processing software, software application Software R package for multivariate analysis and feature selection of omics data. Used for visualization, regression, classification, and feature selection of omics data where the number of variables exceeds the number of samples and with multicollinearity among variables. multivariate, analysis, feature, selection, omics, data, visualization, regression, classification, variable, exceedes, number, sample, multicollinearity, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
Free, Available for download, Freely available BioTools:ropls, biotools:ropls https://bio.tools/ropls
https://bio.tools/ropls
https://bio.tools/ropls
SCR_016888 R Orthogonal Partial Least Squares 2026-02-13 10:57:53 12
riboSeqR
 
Resource Report
Resource Website
1+ mentions
riboSeqR (RRID:SCR_016947) data analysis software, software resource, data processing software, software application Software tool for analysis of sequencing data from ribosome profiling experiments. Used for plotting functions, frameshift detection and parsing of sequencing data from ribosome profiling experiments. analysis, sequencing, data, ribosome, profiling, experiment, plotting, function, frameshift, detect, parsing is listed by: Bioconductor
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_016947 2026-02-13 10:57:53 4
Rsubread
 
Resource Report
Resource Website
100+ mentions
Rsubread (RRID:SCR_016945) data processing software, alignment software, data analysis software, software application, software resource, image analysis software Software R package for sequence alignment and counting for R. Used for analyses of second and third generation sequencing data, for read mapping, read counting, SNP calling, short and long read alignment, quantification and mutation discovery. Includes assessment of sequence reads, read alignment, read summarization, exon-exon junction detection, fusion detection, detection of short and long indels, absolute expression calling and SNP calling. Can be used with reads generated from any of the major sequencing platforms including Illumina GA/HiSeq/MiSeq, Roche GS-FLX, ABI SOLiD and LifeTech Ion PGM/Proton sequencers. sequence, alignment, counting, multi, seed, strategy, mapping, read, reference, genome, analysis, data, SNP, calling, mutation, discovery, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
is related to: Subread
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support ;
Australian Government
PMID:23558742 Free, Available for download, Freely available biotools:rsubread https://bio.tools/rsubread SCR_016945 2026-02-13 10:57:54 188
scran
 
Resource Report
Resource Website
50+ mentions
scran (RRID:SCR_016944) SCRAN data analysis software, software resource, data processing software, software application Software package for low-level analyses of single-cell RNA-seq data. Used for quality control, data exploration and normalization, cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection. low, level, analysis, scRNA-seq, data, normalization, cell, cycle, phase, gene, variable, correlation, cluster, subpopulation, marker, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
Cancer Research UK ;
National Health and Medical Research Council of Australia ;
EMBL
PMID:27909575 Free, Available for download, Freely available biotools:scran https://bio.tools/scran SCR_016944 Single-Cell Rna-seq data ANalysis, SCRAN 2026-02-13 10:57:51 92
Biostrings
 
Resource Report
Resource Website
100+ mentions
Biostrings (RRID:SCR_016949) sequence analysis software, data processing software, data analysis software, software application, software resource Software package for efficient manipulation of biological strings. Memory efficient string containers, string matching algorithms, and other utilities, for fast manipulation of large biological sequences or sets of sequences. manipulation, biological, string, memory, efficient, container, sequence, set, DNA, RNA, protein is used by: riboWaltz
is listed by: Bioconductor
is related to: R Project for Statistical Computing
has parent organization: Stanford University; Stanford; California
Free, Available for download, Freely available https://web.stanford.edu/class/bios221/labs/biostrings/lab_1_biostrings.html SCR_016949 2026-02-13 10:57:51 167
ConsensusClusterPlus
 
Resource Report
Resource Website
100+ mentions
ConsensusClusterPlus (RRID:SCR_016954) data analysis software, software resource, data processing software, software application Software written in R for determining cluster count and membership by stability evidence in unsupervised analysis. Provides quantitative and visual stability evidence for estimating the number of unsupervised classes in a dataset with item tracking, item consensus and cluster consensus plots. cluster, count, stability, evidence, unsupervised, analysis, , bio.tools is listed by: Bioconductor
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
NCI F32CA142039;
Thomas G. Labrecque Foundation ;
NCI U24 CA126554
PMID:20427518 Free, Available for download, Freely available biotools:consensusclusterplus https://bio.tools/consensusclusterplus SCR_016954 2026-02-13 10:57:53 160
GenomicFeatures
 
Resource Report
Resource Website
50+ mentions
GenomicFeatures (RRID:SCR_016960) data processing software, data analysis software, software toolkit, software application, software resource Software R package for making and manipulating transcript centric annotations. Used to download the genomic locations of the transcripts, exons and cds of a given organism, from either the UCSC Genome Browser or a BioMart database. making, manipulating, transcript, centric, annotation, genomic, location, exon, cds, bio.tools is used by: riboWaltz
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
NHGRI P41 HG004059;
NHGRI U41 HG004059;
NHLBI R01 HL086601;
NHLBI R01 HL093076;
NHLBI R01 HL094635
PMID:23950696 Free, Available for download, Freely available biotools:genomicfeatures https://bio.tools/genomicfeatures SCR_016960 2026-02-13 10:57:48 65
Goseq
 
Resource Report
Resource Website
100+ mentions
Goseq (RRID:SCR_017052) data analysis software, software resource, data processing software, software application Software application for performing Gene Ontology analysis on RNAseq data and other length biased data. Used to reduce complexity and highlight biological processes in genome wide expression studies. Gene, Ontology, analysis, RNAseq, data, sequencing, genome, expression, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
PMID:20132535 Free, Available for download, Freely available biotools:goseq https://bio.tools/goseq SCR_017052 2026-02-13 10:57:55 354
Genomic Ranges
 
Resource Report
Resource Website
1+ mentions
Genomic Ranges (RRID:SCR_017051) data processing software, data analysis software, software toolkit, software application, software resource Software R package for computing and annotating genomic ranges. Used for storing and manipulating genomic intervals and variables defined along genome. computing, annotating, genomic, range, storing, manipulating, interval, variable, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
NHGRI P41 HG004059;
NHGRI U41 HG004059;
NHLBI R01 HL086601;
NHLBI R01 HL093076;
NHLBI R01 HL094635
PMID:23950696 Free, Available for download, Freely available biotools:genomicranges https://bio.tools/genomicranges SCR_017051 2026-02-13 10:57:56 2
cn.FARMS
 
Resource Report
Resource Website
cn.FARMS (RRID:SCR_000289) cn.FARMS data processing software, data analysis software, software toolkit, software application, software resource Software R package for copy number variation analysis that allows analysis of the most common Affymetrix (250K-SNP6.0) array types and supports high-performance computing using snow and ff. copy number variation analysis, copy number variation, microarray, affymetrix, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:21486749 Free, Available for download, Freely available biotools:cn.farms, OMICS_02060 https://bio.tools/cn.farms SCR_000289 cn.farms - factor analysis for copy number estimation 2026-02-13 10:54:38 0
CorMut
 
Resource Report
Resource Website
CorMut (RRID:SCR_000053) sequence analysis software, data processing software, data analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16,2023. Software package for computing correlated mutations based on selection pressure. Three methods are provided for detecting correlated mutations, including conditional selection pressure, mutual information and Jaccard index. The computation consists of two steps: First, the positive selection sites are detected; second, the mutation correlations are computed among the positive selection sites. Note that the first step is optional. Meanwhile, CorMut facilitates the comparison of the correlated mutations between two conditions by the means of correlated mutation network. sequencing, correlated mutation, selection pressure, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: CRAN
has parent organization: Bioconductor
PMID:24681904 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_03636, biotools:cormut https://bio.tools/cormut SCR_000053 CorMut - Detect the correlated mutations based on selection pressure 2026-02-13 10:54:36 0
metaSeq
 
Resource Report
Resource Website
metaSeq (RRID:SCR_000056) metaSeq data analysis software, software resource, data processing software, software application Software package for meta-analysis of RNA-Seq count data in multiple studies. The probabilities by one-sided NOISeq are combined by Fisher's method or Stouffer's method. differential expression, rna-seq, sequencing is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02123 SCR_000056 2026-02-13 10:54:36 0
factDesign
 
Resource Report
Resource Website
factDesign (RRID:SCR_001330) factDesign data analysis software, software resource, data processing software, software application Software package that provides a set of tools for analyzing data from a factorial designed microarray experiment, or any microarray experiment for which a linear model is appropriate. The functions can be used to evaluate tests of contrast of biological interest and perform single outlier detection. microarray, differential expression is listed by: OMICtools
has parent organization: Bioconductor
PMID:18584033 Free, Available for download, Freely available OMICS_02008 SCR_001330 factDesign - Factorial designed microarray experiment analysis 2026-02-13 10:54:50 0
spotSegmentation
 
Resource Report
Resource Website
spotSegmentation (RRID:SCR_001298) spotSegmentation image processing software, software resource, data processing software, software application Model-based software package for processing microarray images so as to estimate foreground and background intensities. The method starts with a very simple but effective automatic gridding method, and then proceeds in two steps. The first step applies model-based clustering to the distribution of pixel intensities, using the Bayesian Information Criterion (BIC) to choose the number of groups up to a maximum of three. The second step is spatial, finding the large spatially connected components in each cluster of pixels. The method thus combines the strengths of the histogram-based and spatial approaches. It deals effectively with inner holes in spots and with artifacts. It also provides a formal inferential basis for deciding when the spot is blank, namely when the BIC favors one group over two or three. gridding, segmentation, microarray, preprocessing, quality control, two channel is listed by: OMICtools
has parent organization: Bioconductor
PMID:15845656 Free, Available for download, Freely available OMICS_02037 http://www.bioconductor.org/packages/release/bioc/html/spotSegmentation.html SCR_001298 2026-02-13 10:54:50 0

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